| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ivermectin perturbation in NCI-H596 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ivermectin_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL6A3 | collagen, type VI, alpha 3 | 0.19473 |
| ENO1 | enolase 1, (alpha) | 0.132706 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.127128 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.124972 |
| DST | dystonin | 0.120126 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.108754 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.105291 |
| PDE10A | phosphodiesterase 10A | 0.104136 |
| POTEF | POTE ankyrin domain family, member F | 0.095144 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | 0.0949009 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0948587 |
| FN1 | fibronectin 1 | 0.0933429 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0911986 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0904847 |
| ASPH | aspartate beta-hydroxylase | 0.089951 |
| SLC38A1 | solute carrier family 38, member 1 | 0.0888918 |
| B2M | beta-2-microglobulin | 0.0880402 |
| SQSTM1 | sequestosome 1 | 0.0852524 |
| FTL | ferritin, light polypeptide | 0.0846632 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0844671 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0818513 |
| NDRG1 | N-myc downstream regulated 1 | 0.0803939 |
| ERBIN | erbb2 interacting protein | 0.0792053 |
| BRD2 | bromodomain containing 2 | 0.0715957 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0677587 |
| SMYD3 | SET and MYND domain containing 3 | 0.065607 |
| EXOC6B | exocyst complex component 6B | 0.0647051 |
| OXR1 | oxidation resistance 1 | 0.0635387 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0609736 |
| PGK1 | phosphoglycerate kinase 1 | 0.055374 |
| FHIT | fragile histidine triad | 0.0552714 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0543112 |
| RAPGEF6 | Rap guanine nucleotide exchange factor (GEF) 6 | 0.0539845 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0532965 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0521156 |
| AHNAK | AHNAK nucleoprotein | 0.0507278 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0505727 |
| SUCO | SUN domain containing ossification factor | 0.0496813 |
| ZNF609 | zinc finger protein 609 | 0.0496236 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | 0.0493636 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0483085 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0479201 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.0464199 |
| SPIDR | scaffolding protein involved in DNA repair | 0.0462073 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0460906 |
| ACTG1 | actin gamma 1 | 0.0460527 |
| INHBA | inhibin, beta A | 0.0456482 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0443032 |
| FAT1 | FAT atypical cadherin 1 | 0.0442446 |
| DSPP | dentin sialophosphoprotein | 0.0435025 |
| PARD3 | par-3 family cell polarity regulator | 0.0425927 |
| HDAC9 | histone deacetylase 9 | 0.0425321 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | 0.0423371 |
| AGO3 | argonaute RISC catalytic component 3 | 0.041145 |
| GOLGA4 | golgin A4 | 0.040161 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0401584 |
| MED13L | mediator complex subunit 13-like | 0.0394764 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0393433 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.038976 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0374299 |
| ZNF638 | zinc finger protein 638 | 0.0366049 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0348107 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0344498 |
| EHBP1 | EH domain binding protein 1 | 0.0338084 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0329175 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | 0.0323568 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0321089 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0320871 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0313749 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0313582 |
| RNF145 | ring finger protein 145 | 0.0309252 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0305981 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0297176 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0284522 |
| MCL1 | myeloid cell leukemia 1 | 0.0281263 |
| OSMR | oncostatin M receptor | 0.0279967 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | 0.0276468 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0259455 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0255829 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0254512 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | 0.0250485 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0249378 |
| COG5 | component of oligomeric golgi complex 5 | 0.0229071 |
| GPC6 | glypican 6 | 0.0226595 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0222754 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0222283 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0221937 |
| EGFR | epidermal growth factor receptor | 0.0215339 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0206779 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0201506 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0190832 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0188002 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0177206 |
| TNRC6B | trinucleotide repeat containing 6B | 0.0169304 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.016898 |
| NRXN3 | neurexin 3 | 0.0168336 |
| CD44 | CD44 molecule (Indian blood group) | 0.0159182 |
| RPL37 | ribosomal protein L37 | 0.015108 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0150687 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0139051 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.244936 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.211175 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.169233 |
| VIM | vimentin | -0.163677 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.163449 |
| LAMA4 | laminin, alpha 4 | -0.160404 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.134796 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.131394 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.119599 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.117184 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.105614 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.102302 |
| SPAG9 | sperm associated antigen 9 | -0.0968873 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.09547 |
| PTMA | prothymosin, alpha | -0.0915726 |
| CDH13 | cadherin 13 | -0.0881895 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0811468 |
| SLTM | SAFB-like, transcription modulator | -0.072881 |
| SMC5 | structural maintenance of chromosomes 5 | -0.0723538 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.0689318 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0688739 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0685062 |
| RPL15 | ribosomal protein L15 | -0.0664944 |
| EFNA5 | ephrin-A5 | -0.0652963 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0647926 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0643776 |
| PDLIM5 | PDZ and LIM domain 5 | -0.063922 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0638561 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0616949 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0604162 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0598129 |
| JMJD1C | jumonji domain containing 1C | -0.0578924 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0569499 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0547673 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0515079 |
| PRKCA | protein kinase C, alpha | -0.0511625 |
| RPS8 | ribosomal protein S8 | -0.050273 |
| RSF1 | remodeling and spacing factor 1 | -0.0502201 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0498108 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.0485241 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | -0.0484486 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0479352 |
| FNIP1 | folliculin interacting protein 1 | -0.0473368 |
| FNDC3B | fibronectin type III domain containing 3B | -0.046989 |
| GOLGB1 | golgin B1 | -0.0455427 |
| MYO10 | myosin X | -0.0454472 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0445284 |
| RPS13 | ribosomal protein S13 | -0.0443909 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0429199 |
| OGA | O-GlcNAcase | -0.0426291 |
| TUT7 | terminal uridylyl transferase 7 | -0.0421664 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0411024 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0403537 |
| ATXN1 | ataxin 1 | -0.0402576 |
| GPHN | gephyrin | -0.0397875 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0383821 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0373857 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0369123 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0368944 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0350607 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | -0.0349743 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0339976 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0333663 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.031417 |
| MYO1E | myosin IE | -0.0302963 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.030081 |
| TMEM165 | transmembrane protein 165 | -0.0300189 |
| USP34 | ubiquitin specific peptidase 34 | -0.0298522 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0291588 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0285311 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.028507 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0269349 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0255323 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0253815 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0243427 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0240598 |
| EGR1 | early growth response 1 | -0.0239368 |
| CANX | calnexin | -0.0237665 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0230308 |
| FNDC3A | fibronectin type III domain containing 3A | -0.02237 |
| CAMK2D | calcium/calmodulin-dependent protein kinase II delta | -0.0220244 |
| MORF4L2 | mortality factor 4 like 2 | -0.0213067 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0210682 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0209463 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0202639 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0197527 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0196476 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0196086 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | -0.0190845 |
| PRELID2 | PRELI domain containing 2 | -0.018918 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0184991 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0176731 |
| RUNX1 | runt-related transcription factor 1 | -0.0151249 |
| MYOF | myoferlin | -0.0150553 |
| SBF2 | SET binding factor 2 | -0.0145915 |
| SNX9 | sorting nexin 9 | -0.0142499 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0136963 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0135578 |
| AREG | amphiregulin | -0.013336 |
| DPP10 | dipeptidyl-peptidase 10 (non-functional) | -0.0132857 |
