| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ivermectin perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ivermectin_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PEG10 | paternally expressed 10 | 0.0679367 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0542713 |
| CENPF | centromere protein F, 350/400kDa | 0.0467922 |
| HMGB2 | high mobility group box 2 | 0.0402746 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0356638 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0353521 |
| PRR16 | proline rich 16 | 0.0341292 |
| POLR2B | polymerase (RNA) II (DNA directed) polypeptide B, 140kDa | 0.0328633 |
| BLTP1 | bridge-like lipid transfer protein family member 1 | 0.0312725 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0308292 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0307856 |
| ANXA5 | annexin A5 | 0.0307617 |
| CRISPLD1 | cysteine-rich secretory protein LCCL domain containing 1 | 0.0300619 |
| FUBP1 | far upstream element (FUSE) binding protein 1 | 0.0298461 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0292931 |
| RPL3 | ribosomal protein L3 | 0.0290559 |
| PRPF8 | pre-mRNA processing factor 8 | 0.0290264 |
| POTEF | POTE ankyrin domain family, member F | 0.0282465 |
| NUP58 | nucleoporin 58 | 0.0271396 |
| CCNA2 | cyclin A2 | 0.0264821 |
| PNN | pinin, desmosome associated protein | 0.0248385 |
| DST | dystonin | 0.0245406 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0245322 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0235552 |
| NCKAP1 | NCK-associated protein 1 | 0.0234969 |
| CENPE | centromere protein E, 312kDa | 0.0232844 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | 0.0231722 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0221858 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.021784 |
| CEP192 | centrosomal protein 192kDa | 0.0214711 |
| FNBP1L | formin binding protein 1-like | 0.0211966 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0203271 |
| FAT1 | FAT atypical cadherin 1 | 0.0201358 |
| CCNL1 | cyclin L1 | 0.0200305 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0200219 |
| DIDO1 | death inducer-obliterator 1 | 0.0198755 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.01947 |
| ACTN4 | actinin, alpha 4 | 0.0194198 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0193673 |
| TCP1 | t-complex 1 | 0.0192912 |
| ZNF146 | zinc finger protein 146 | 0.0192756 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0190603 |
| YAP1 | Yes-associated protein 1 | 0.0190155 |
| MKI67 | marker of proliferation Ki-67 | 0.0189425 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0187634 |
| DPY19L1 | dpy-19-like 1 (C. elegans) | 0.0185369 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0184729 |
| FIGN | fidgetin | 0.0183986 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | 0.0182834 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.018264 |
| RBM39 | RNA binding motif protein 39 | 0.0180193 |
| CPNE8 | copine VIII | 0.0179754 |
| PDS5B | PDS5 cohesin associated factor B | 0.0176333 |
| SUCO | SUN domain containing ossification factor | 0.0176241 |
| SETD5 | SET domain containing 5 | 0.017573 |
| MIER1 | mesoderm induction early response 1, transcriptional regulator | 0.0175644 |
| USP3 | ubiquitin specific peptidase 3 | 0.0175201 |
| MATR3 | matrin 3 | 0.0174546 |
| ECT2 | epithelial cell transforming 2 | 0.0173752 |
| MRE11 | MRE11 homolog, double strand break repair nuclease | 0.0173546 |
| LBR | lamin B receptor | 0.0171598 |
| USP14 | ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) | 0.0171502 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0170778 |
| ATF7IP | activating transcription factor 7 interacting protein | 0.0170349 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0169858 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0168486 |
| SRRT | serrate, RNA effector molecule | 0.0167952 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0165857 |
| SP3 | Sp3 transcription factor | 0.0165121 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0164838 |
| URI1 | URI1, prefoldin-like chaperone | 0.0164423 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0164277 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | 0.016197 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0161429 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | 0.0161191 |
| TEX11 | testis expressed 11 | 0.0160394 |
| HBS1L | HBS1-like translational GTPase | 0.0160338 |
| PPIL4 | peptidylprolyl isomerase (cyclophilin)-like 4 | 0.0160232 |
| TLK2 | tousled-like kinase 2 | 0.0160071 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0159795 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0159409 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0159383 |
| EIF5AL1 | eukaryotic translation initiation factor 5A-like 1 | 0.015608 |
| CDC27 | cell division cycle 27 | 0.0155596 |
| U2SURP | U2 snRNP-associated SURP domain containing | 0.0154953 |
| TWSG1 | twisted gastrulation BMP signaling modulator 1 | 0.0154438 |
| DHFR | dihydrofolate reductase | 0.0154351 |
| TSR1 | TSR1, 20S rRNA accumulation, homolog (S. cerevisiae) | 0.0153498 |
| WDR26 | WD repeat domain 26 | 0.015276 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0151939 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0151571 |
| ZNF292 | zinc finger protein 292 | 0.0151413 |
| ETNK1 | ethanolamine kinase 1 | 0.0150188 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0149995 |
| KCTD3 | potassium channel tetramerization domain containing 3 | 0.0149731 |
| RTTN | rotatin | 0.0149205 |
| KDM1A | lysine (K)-specific demethylase 1A | 0.0149163 |
| SET | SET nuclear proto-oncogene | 0.0148954 |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 | 0.0148212 |
| WASL | Wiskott-Aldrich syndrome-like | 0.0148106 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.168824 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.150796 |
| PCDH9 | protocadherin 9 | -0.144389 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.139765 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.131582 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.122767 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.117919 |
| CADM2 | cell adhesion molecule 2 | -0.117067 |
| VIM | vimentin | -0.115938 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.113251 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.112335 |
| TMSB10 | thymosin beta 10 | -0.108966 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | -0.0954638 |
| COL3A1 | collagen, type III, alpha 1 | -0.0934668 |
| RPS16 | ribosomal protein S16 | -0.0866062 |
| RPS8 | ribosomal protein S8 | -0.0853089 |
| PTMA | prothymosin, alpha | -0.0836295 |
| PLPP1 | phospholipid phosphatase 1 | -0.0752113 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0750869 |
| SNX6 | sorting nexin 6 | -0.0650487 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | -0.0642578 |
| COL1A2 | collagen, type I, alpha 2 | -0.0639908 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0628244 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | -0.0618687 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0617988 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0611804 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0589724 |
| PHIP | pleckstrin homology domain interacting protein | -0.0550174 |
| RPL35A | ribosomal protein L35a | -0.0545963 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0542001 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.0541799 |
| GNAS | GNAS complex locus | -0.0533819 |
| SMYD3 | SET and MYND domain containing 3 | -0.0530953 |
| RPS6 | ribosomal protein S6 | -0.0528013 |
| RPS27A | ribosomal protein S27a | -0.0525867 |
| ACTG1 | actin gamma 1 | -0.0522905 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0504803 |
| ITGAV | integrin, alpha V | -0.0500557 |
| PARD3B | par-3 family cell polarity regulator beta | -0.0498914 |
| GPC3 | glypican 3 | -0.0488626 |
| NRG1 | neuregulin 1 | -0.0485167 |
| RAD51B | RAD51 paralog B | -0.0478665 |
| RPLP1 | ribosomal protein, large, P1 | -0.0475759 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0466397 |
| AHNAK | AHNAK nucleoprotein | -0.0465515 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0463761 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0462815 |
| TUT4 | terminal uridylyl transferase 4 | -0.0440723 |
| NEBL | nebulette | -0.0439219 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0437501 |
| TNRC6B | trinucleotide repeat containing 6B | -0.0436799 |
| SOX2 | SRY (sex determining region Y)-box 2 | -0.043414 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0433589 |
| ENO1 | enolase 1, (alpha) | -0.0417556 |
| COL11A1 | collagen, type XI, alpha 1 | -0.0416181 |
| NPAS3 | neuronal PAS domain protein 3 | -0.040959 |
| SYT1 | synaptotagmin I | -0.0408042 |
| EMP1 | epithelial membrane protein 1 | -0.040049 |
| ADGRV1 | adhesion G protein-coupled receptor V1 | -0.0392628 |
| RPS12 | ribosomal protein S12 | -0.0383896 |
| NCAM2 | neural cell adhesion molecule 2 | -0.03797 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.037925 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0379038 |
| RPL37 | ribosomal protein L37 | -0.0375921 |
| PGK1 | phosphoglycerate kinase 1 | -0.0374815 |
| RAB31 | RAB31, member RAS oncogene family | -0.037227 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0368843 |
| ANKRD33B | ankyrin repeat domain 33B | -0.0368142 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | -0.0363141 |
| RPS24 | ribosomal protein S24 | -0.0362082 |
| RPS13 | ribosomal protein S13 | -0.0361496 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0359828 |
| PRELID2 | PRELI domain containing 2 | -0.0356901 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0355207 |
| RPL26 | ribosomal protein L26 | -0.0353681 |
| CALR | calreticulin | -0.0349114 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0347489 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0347459 |
| RBM20 | RNA binding motif protein 20 | -0.034725 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0346961 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0344012 |
| TENM3 | teneurin transmembrane protein 3 | -0.0342858 |
| RPS21 | ribosomal protein S21 | -0.0342293 |
| RPL23 | ribosomal protein L23 | -0.0341731 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0341484 |
| B2M | beta-2-microglobulin | -0.0340982 |
| RPL37A | ribosomal protein L37a | -0.0336843 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0330348 |
| SPAG9 | sperm associated antigen 9 | -0.0328882 |
| CDH19 | cadherin 19, type 2 | -0.0327545 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | -0.0325941 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0320848 |
| FTL | ferritin, light polypeptide | -0.0319958 |
| UPP1 | uridine phosphorylase 1 | -0.0315904 |
| MEIS2 | Meis homeobox 2 | -0.0313212 |
| RPLP2 | ribosomal protein, large, P2 | -0.0312556 |
| FOXP2 | forkhead box P2 | -0.0307879 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0307793 |
| CDK13 | cyclin-dependent kinase 13 | -0.0306905 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0306017 |
