| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ivermectin perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ivermectin_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.139893 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.126282 |
| PKM | pyruvate kinase, muscle | 0.112559 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0897941 |
| NBEA | neurobeachin | 0.088512 |
| FOXP1 | forkhead box P1 | 0.0850731 |
| TJP1 | tight junction protein 1 | 0.0850287 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.084091 |
| VCL | vinculin | 0.0838288 |
| EGFR | epidermal growth factor receptor | 0.0826051 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0780513 |
| TXNRD1 | thioredoxin reductase 1 | 0.076247 |
| PYGB | phosphorylase, glycogen; brain | 0.0752429 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.073272 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0724563 |
| FLNB | filamin B, beta | 0.0709213 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0700273 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0697387 |
| HDAC9 | histone deacetylase 9 | 0.0679663 |
| RBM39 | RNA binding motif protein 39 | 0.066989 |
| EFNA5 | ephrin-A5 | 0.06683 |
| PDGFC | platelet derived growth factor C | 0.0660194 |
| PTMA | prothymosin, alpha | 0.0642562 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0640719 |
| ANK2 | ankyrin 2, neuronal | 0.0638819 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0633047 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0593357 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0576633 |
| JMJD1C | jumonji domain containing 1C | 0.0573892 |
| TMSB4X | thymosin beta 4, X-linked | 0.0573045 |
| TMEM65 | transmembrane protein 65 | 0.0563374 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0540443 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0523982 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | 0.0523904 |
| LDHA | lactate dehydrogenase A | 0.0522648 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 | 0.051706 |
| DUSP4 | dual specificity phosphatase 4 | 0.0496329 |
| RPS6 | ribosomal protein S6 | 0.0486156 |
| NF1 | neurofibromin 1 | 0.0483976 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0477267 |
| SOX6 | SRY (sex determining region Y)-box 6 | 0.0473293 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0458686 |
| DOCK3 | dedicator of cytokinesis 3 | 0.0449081 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0446777 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.0439968 |
| RHOA | ras homolog family member A | 0.0436278 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0432909 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0431432 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0427422 |
| EML4 | echinoderm microtubule associated protein like 4 | 0.0427356 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0426261 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0414119 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0406921 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0398201 |
| SMYD3 | SET and MYND domain containing 3 | 0.0396032 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.0395755 |
| TCF12 | transcription factor 12 | 0.03897 |
| GOLGA4 | golgin A4 | 0.0388693 |
| CCNL1 | cyclin L1 | 0.0388079 |
| SQSTM1 | sequestosome 1 | 0.0387207 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0373668 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0371202 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0370741 |
| VMP1 | vacuole membrane protein 1 | 0.0370452 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0368913 |
| PARD3 | par-3 family cell polarity regulator | 0.0358743 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0358233 |
| BMP2K | BMP2 inducible kinase | 0.03487 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0347236 |
| RTN4 | reticulon 4 | 0.0343534 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | 0.0339979 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0334931 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0334329 |
| DIAPH2 | diaphanous-related formin 2 | 0.0331104 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0330678 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0327469 |
| PPP1R9A | protein phosphatase 1, regulatory subunit 9A | 0.0325899 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0323817 |
| MAP4 | microtubule-associated protein 4 | 0.0322925 |
| SPIDR | scaffolding protein involved in DNA repair | 0.032007 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0317929 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | 0.0317756 |
| METTL15 | methyltransferase like 15 | 0.0314909 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.031241 |
| NBAS | neuroblastoma amplified sequence | 0.0311813 |
| XKR6 | XK, Kell blood group complex subunit-related family, member 6 | 0.031181 |
| USP34 | ubiquitin specific peptidase 34 | 0.0309534 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.030793 |
| LOXL3 | lysyl oxidase-like 3 | 0.0304809 |
| TMEM41B | transmembrane protein 41B | 0.0302716 |
| NCKAP1 | NCK-associated protein 1 | 0.0301634 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.0298155 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | 0.0296828 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0296707 |
| POTEF | POTE ankyrin domain family, member F | 0.0296614 |
| ANXA1 | annexin A1 | 0.029445 |
| OSMR | oncostatin M receptor | 0.0294448 |
| ARL4C | ADP-ribosylation factor-like 4C | 0.02924 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0291448 |
| GLI2 | GLI family zinc finger 2 | 0.029117 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0357053 |
| RRBP1 | ribosome binding protein 1 | -0.0240728 |
| INTS6 | integrator complex subunit 6 | -0.0222107 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0194241 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 | -0.0189096 |
| GALNT5 | polypeptide N-acetylgalactosaminyltransferase 5 | -0.0175299 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | -0.0169824 |
| BMP10 | bone morphogenetic protein 10 | -0.0166108 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.0155109 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0150347 |
| FN1 | fibronectin 1 | -0.014491 |
| NAV2 | neuron navigator 2 | -0.0142986 |
| RRM2 | ribonucleotide reductase M2 | -0.0141998 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0141168 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.013866 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0138616 |
| CENPP | centromere protein P | -0.0135698 |
| FTL | ferritin, light polypeptide | -0.0133262 |
| RPLP1 | ribosomal protein, large, P1 | -0.0133249 |
| NDRG1 | N-myc downstream regulated 1 | -0.013076 |
| CENPE | centromere protein E, 312kDa | -0.0127172 |
| MYOF | myoferlin | -0.0121624 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0121162 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.0120901 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0114474 |
| MSH4 | mutS homolog 4 | -0.0114336 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.011315 |
| CFAP251 | cilia and flagella associated protein 251 | -0.0111256 |
| SCG5 | secretogranin V | -0.0109462 |
| AEBP2 | AE binding protein 2 | -0.0107229 |
| CADM1 | cell adhesion molecule 1 | -0.0105439 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0103746 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0100179 |
| ZNF106 | zinc finger protein 106 | -0.00996195 |
| FER1L6 | fer-1-like family member 6 | -0.00979713 |
| TXK | TXK tyrosine kinase | -0.00976342 |
| H1-4 | H1.4 linker histone, cluster member | -0.00965112 |
| RPL36 | ribosomal protein L36 | -0.00956699 |
| REEP3 | receptor accessory protein 3 | -0.00950267 |
| CD44 | CD44 molecule (Indian blood group) | -0.00917924 |
| GNB5 | guanine nucleotide binding protein (G protein), beta 5 | -0.00917172 |
| EED | embryonic ectoderm development | -0.00903086 |
| PAIP2 | poly(A) binding protein interacting protein 2 | -0.00899571 |
| ABCA10 | ATP-binding cassette, sub-family A (ABC1), member 10 | -0.00881918 |
| ATAD2 | ATPase family, AAA domain containing 2 | -0.00881905 |
| CDKL1 | cyclin-dependent kinase-like 1 (CDC2-related kinase) | -0.00878592 |
| FBH1 | F-box DNA helicase 1 | -0.00875983 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -0.00862641 |
| MT2A | metallothionein 2A | -0.00860468 |
| RAD18 | RAD18 E3 ubiquitin protein ligase | -0.00857156 |
| CALR | calreticulin | -0.00848317 |
| TBCA | tubulin folding cofactor A | -0.00843366 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.00840619 |
| ORAI2 | ORAI calcium release-activated calcium modulator 2 | -0.00836456 |
| MYH15 | myosin, heavy chain 15 | -0.00836066 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.00822162 |
| TOP1 | topoisomerase (DNA) I | -0.00820239 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.00818828 |
| CDH13 | cadherin 13 | -0.00807776 |
| SLC33A1 | solute carrier family 33 (acetyl-CoA transporter), member 1 | -0.00804794 |
| IGF2 | insulin-like growth factor 2 | -0.00803237 |
| HELZ | helicase with zinc finger | -0.00793236 |
| GPR75-ASB3 | GPR75-ASB3 readthrough | -0.00790157 |
| DNAJC6 | DnaJ (Hsp40) homolog, subfamily C, member 6 | -0.00784545 |
| ANXA2 | annexin A2 | -0.00782832 |
| FLCN | folliculin | -0.00780467 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0077793 |
| PTCD3 | pentatricopeptide repeat domain 3 | -0.00775916 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.00773669 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | -0.00767489 |
| UGGT1 | UDP-glucose glycoprotein glucosyltransferase 1 | -0.00764729 |
| GPC6 | glypican 6 | -0.00764387 |
| RNF169 | ring finger protein 169 | -0.00762872 |
| MED26 | mediator complex subunit 26 | -0.00762321 |
| FOXN3 | forkhead box N3 | -0.00762211 |
| FGF18 | fibroblast growth factor 18 | -0.00756164 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.00754031 |
| TNIK | TRAF2 and NCK interacting kinase | -0.00752329 |
| TNS3 | tensin 3 | -0.00751851 |
| AP3S1 | adaptor-related protein complex 3, sigma 1 subunit | -0.00751606 |
| TMSB10 | thymosin beta 10 | -0.0075156 |
| CEP128 | centrosomal protein 128kDa | -0.00750126 |
| SRP19 | signal recognition particle 19kDa | -0.00746938 |
| VIM | vimentin | -0.00746591 |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) | -0.00745394 |
| FARP2 | FERM, RhoGEF and pleckstrin domain protein 2 | -0.00739313 |
| HMMR | hyaluronan-mediated motility receptor (RHAMM) | -0.00739015 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.00737255 |
| NEK10 | NIMA-related kinase 10 | -0.00737034 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.00734007 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.00732566 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.00730606 |
| ANKDD1B | ankyrin repeat and death domain containing 1B | -0.00727437 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.00725084 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.00718599 |
| POLH | polymerase (DNA directed), eta | -0.00715467 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | -0.00711712 |
| SH3TC2 | SH3 domain and tetratricopeptide repeats 2 | -0.00711691 |
| PCNX4 | pecanex 4 | -0.00705889 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.00704424 |