| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ivermectin perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ivermectin_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL6A3 | collagen, type VI, alpha 3 | 0.107521 |
| COL5A1 | collagen, type V, alpha 1 | 0.0680266 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0534555 |
| FNIP1 | folliculin interacting protein 1 | 0.0511685 |
| MSN | moesin | 0.0487149 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0432993 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.042782 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0404937 |
| ANLN | anillin, actin binding protein | 0.0391656 |
| SUCO | SUN domain containing ossification factor | 0.0380534 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0368306 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0368247 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0363414 |
| AUTS2 | autism susceptibility candidate 2 | 0.0351126 |
| MTREX | Mtr4 exosome RNA helicase | 0.0336861 |
| RINT1 | RAD50 interactor 1 | 0.0335902 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0334719 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0334209 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0331709 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0318823 |
| LAMB1 | laminin, beta 1 | 0.0317568 |
| MATR3 | matrin 3 | 0.0312042 |
| NAV2 | neuron navigator 2 | 0.0310131 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0309388 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0308989 |
| CDK13 | cyclin-dependent kinase 13 | 0.0305911 |
| XPO1 | exportin 1 | 0.0304857 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0303711 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0301658 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0301571 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0300517 |
| COPA | coatomer protein complex, subunit alpha | 0.029234 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0291553 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0290993 |
| HAPSTR1 | HUWE1 associated protein modifying stress responses | 0.0287952 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0284193 |
| APP | amyloid beta (A4) precursor protein | 0.0280726 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | 0.0272931 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0267439 |
| SON | SON DNA binding protein | 0.0266457 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0265093 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.026386 |
| DNPEP | aspartyl aminopeptidase | 0.0263581 |
| POT1 | protection of telomeres 1 | 0.0261294 |
| PMM2 | phosphomannomutase 2 | 0.0261238 |
| RBM33 | RNA binding motif protein 33 | 0.0260494 |
| BLTP1 | bridge-like lipid transfer protein family member 1 | 0.0260235 |
| IL6 | interleukin 6 | 0.0260131 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | 0.0258739 |
| COL4A2 | collagen, type IV, alpha 2 | 0.0256454 |
| TMF1 | TATA element modulatory factor 1 | 0.0254658 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0252362 |
| HYOU1 | hypoxia up-regulated 1 | 0.0251005 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0249313 |
| FMNL2 | formin-like 2 | 0.0249214 |
| EGR1 | early growth response 1 | 0.0249087 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.024623 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | 0.0246188 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0245079 |
| ARFGEF1 | ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited) | 0.0242304 |
| CUL3 | cullin 3 | 0.0241318 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0238629 |
| PTGES2 | prostaglandin E synthase 2 | 0.0238591 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0237894 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0237371 |
| FLNA | filamin A, alpha | 0.02362 |
| WTAP | Wilms tumor 1 associated protein | 0.0232829 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0232061 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0231332 |
| ARFIP1 | ADP-ribosylation factor interacting protein 1 | 0.0230544 |
| MARCHF7 | membrane associated ring-CH-type finger 7 | 0.0230544 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0230526 |
| C1D | C1D nuclear receptor corepressor | 0.022996 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | 0.0228002 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0227919 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0226565 |
| TP53BP1 | tumor protein p53 binding protein 1 | 0.0226121 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | 0.022542 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0224444 |
| RND3 | Rho family GTPase 3 | 0.0223808 |
| TM9SF2 | transmembrane 9 superfamily member 2 | 0.0223552 |
| SEC63 | SEC63 homolog (S. cerevisiae) | 0.0223367 |
| DCAF7 | DDB1 and CUL4 associated factor 7 | 0.0223248 |
| GPR107 | G protein-coupled receptor 107 | 0.0222471 |
| LYSMD3 | LysM, putative peptidoglycan-binding, domain containing 3 | 0.0222149 |
| CDK7 | cyclin-dependent kinase 7 | 0.0220771 |
| HLA-A | major histocompatibility complex, class I, A | 0.0218952 |
| NBAS | neuroblastoma amplified sequence | 0.0217869 |
| POLK | polymerase (DNA directed) kappa | 0.0216625 |
| COL6A1 | collagen, type VI, alpha 1 | 0.0216519 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0216498 |
| VMP1 | vacuole membrane protein 1 | 0.0213893 |
| HDLBP | high density lipoprotein binding protein | 0.0213157 |
| KLHL7 | kelch-like family member 7 | 0.0212617 |
| SNRNP200 | small nuclear ribonucleoprotein 200kDa (U5) | 0.0211367 |
| SLC41A2 | solute carrier family 41 (magnesium transporter), member 2 | 0.0210447 |
| MYADM | myeloid-associated differentiation marker | 0.0210254 |
| NUS1 | nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) | 0.0209745 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0209726 |
| NME7 | NME/NM23 family member 7 | 0.0209445 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.22624 |
| MT2A | metallothionein 2A | -0.161035 |
| TMSB10 | thymosin beta 10 | -0.121108 |
| VIM | vimentin | -0.114443 |
| COL1A1 | collagen, type I, alpha 1 | -0.0887055 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0799301 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0746314 |
| FTL | ferritin, light polypeptide | -0.0717846 |
| ENO1 | enolase 1, (alpha) | -0.0619627 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0579084 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0577562 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0542856 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.052947 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.0524896 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0517768 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0502195 |
| PGK1 | phosphoglycerate kinase 1 | -0.0497026 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0490529 |
| FAM13A | family with sequence similarity 13, member A | -0.048666 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0481234 |
| AHNAK | AHNAK nucleoprotein | -0.0479817 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0458388 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0456312 |
| TPM4 | tropomyosin 4 | -0.0455462 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0450235 |
| COL1A2 | collagen, type I, alpha 2 | -0.0446254 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0440737 |
| H3-3B | H3.3 histone B | -0.041465 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0413603 |
| PTK2 | protein tyrosine kinase 2 | -0.0396179 |
| HIPK2 | homeodomain interacting protein kinase 2 | -0.0395234 |
| MT1X | metallothionein 1X | -0.0385621 |
| ADM | adrenomedullin | -0.0373112 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0372246 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0361706 |
| EFNA5 | ephrin-A5 | -0.0358218 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0356003 |
| GLIS3 | GLIS family zinc finger 3 | -0.0355582 |
| LOX | lysyl oxidase | -0.0354693 |
| ANXA2 | annexin A2 | -0.0346383 |
| CD99 | CD99 molecule | -0.0342665 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.034219 |
| TXNIP | thioredoxin interacting protein | -0.033788 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0332463 |
| TUBB | tubulin, beta class I | -0.0327752 |
| STC1 | stanniocalcin 1 | -0.0326251 |
| KAZN | kazrin, periplakin interacting protein | -0.0325355 |
| RRBP1 | ribosome binding protein 1 | -0.0318589 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0314839 |
| S100A9 | S100 calcium binding protein A9 | -0.0312808 |
| RPL37A | ribosomal protein L37a | -0.0312743 |
| ACTG1 | actin gamma 1 | -0.0311546 |
| COTL1 | coactosin-like F-actin binding protein 1 | -0.0311041 |
| PDE10A | phosphodiesterase 10A | -0.0303281 |
| STC2 | stanniocalcin 2 | -0.0302465 |
| TXNRD1 | thioredoxin reductase 1 | -0.0299114 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0288735 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.028743 |
| PRSS23 | protease, serine, 23 | -0.0286718 |
| MEF2A | myocyte enhancer factor 2A | -0.0286627 |
| RAI14 | retinoic acid induced 14 | -0.0282415 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0279079 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0276934 |
| S100A6 | S100 calcium binding protein A6 | -0.0276812 |
| TMSB4X | thymosin beta 4, X-linked | -0.0269526 |
| EEA1 | early endosome antigen 1 | -0.0266509 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.02658 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0264763 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0263667 |
| ARRDC3 | arrestin domain containing 3 | -0.0262547 |
| HIP1 | huntingtin interacting protein 1 | -0.0262402 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0258399 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0255755 |
| TMOD3 | tropomodulin 3 (ubiquitous) | -0.0253587 |
| CALU | calumenin | -0.0252021 |
| WDR26 | WD repeat domain 26 | -0.0251728 |
| ADNP | activity-dependent neuroprotector homeobox | -0.0251322 |
| GNAS | GNAS complex locus | -0.0250104 |
| H1-0 | H1.0 linker histone | -0.0247955 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | -0.0246059 |
| RPL32 | ribosomal protein L32 | -0.0243713 |
| RPL15 | ribosomal protein L15 | -0.0243254 |
| RPL35A | ribosomal protein L35a | -0.0242525 |
| CA12 | carbonic anhydrase XII | -0.0238182 |
| SEPTIN7 | septin 7 | -0.0237442 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.0234678 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0234126 |
| ATXN1 | ataxin 1 | -0.0232685 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0232436 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0231924 |
| IKBIP | IKBKB interacting protein | -0.023137 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0229727 |
| RPL4 | ribosomal protein L4 | -0.022958 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0228338 |
| CD44 | CD44 molecule (Indian blood group) | -0.0228158 |
| FAM120B | family with sequence similarity 120B | -0.0228019 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0225841 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0223909 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0223859 |
| RAB31 | RAB31, member RAS oncogene family | -0.0223326 |
