| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ivermectin perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ivermectin_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NRG1 | neuregulin 1 | 0.166934 |
| FN1 | fibronectin 1 | 0.133102 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0983426 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.0927826 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0705522 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.0625889 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0611106 |
| HMGA2 | high mobility group AT-hook 2 | 0.0608868 |
| STC2 | stanniocalcin 2 | 0.055504 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0483908 |
| MRPS6 | mitochondrial ribosomal protein S6 | 0.0431061 |
| PKM | pyruvate kinase, muscle | 0.0421353 |
| POTEF | POTE ankyrin domain family, member F | 0.0421107 |
| VEGFA | vascular endothelial growth factor A | 0.0416712 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0404123 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0382727 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0346408 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0341485 |
| PLIN2 | perilipin 2 | 0.0324977 |
| RAI14 | retinoic acid induced 14 | 0.0309462 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0296798 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0291809 |
| EFNA5 | ephrin-A5 | 0.0289632 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0288536 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0274586 |
| AHRR | aryl-hydrocarbon receptor repressor | 0.0270578 |
| AEBP2 | AE binding protein 2 | 0.025511 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0253252 |
| CADM1 | cell adhesion molecule 1 | 0.0245397 |
| ENO1 | enolase 1, (alpha) | 0.023967 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0216492 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0210051 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0209456 |
| INTS6 | integrator complex subunit 6 | 0.0208134 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0206383 |
| CTBP2 | C-terminal binding protein 2 | 0.0205453 |
| CALR | calreticulin | 0.0197195 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0195183 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0193308 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0189298 |
| TMSB10 | thymosin beta 10 | 0.0187542 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0185951 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0184245 |
| ADIPOR2 | adiponectin receptor 2 | 0.0183078 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0182665 |
| SLC35F3 | solute carrier family 35, member F3 | 0.018062 |
| DNAH5 | dynein, axonemal, heavy chain 5 | 0.0179918 |
| TNS3 | tensin 3 | 0.0166329 |
| FBN1 | fibrillin 1 | 0.0166238 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0165506 |
| GLIS3 | GLIS family zinc finger 3 | 0.0160546 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0160505 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | 0.0159539 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.015546 |
| FAM20C | family with sequence similarity 20, member C | 0.0154455 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0147936 |
| CD46 | CD46 molecule, complement regulatory protein | 0.014396 |
| RPL3 | ribosomal protein L3 | 0.0143952 |
| TENM4 | teneurin transmembrane protein 4 | 0.0140415 |
| BRD2 | bromodomain containing 2 | 0.0137947 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0137031 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0136457 |
| HMGA1 | high mobility group AT-hook 1 | 0.0135977 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0134984 |
| PALLD | palladin, cytoskeletal associated protein | 0.0131561 |
| IL6 | interleukin 6 | 0.0130931 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0130777 |
| RPS4X | ribosomal protein S4, X-linked | 0.0128493 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A | 0.0125416 |
| PPP1R15B | protein phosphatase 1, regulatory subunit 15B | 0.0125118 |
| ANP32E | acidic (leucine-rich) nuclear phosphoprotein 32 family, member E | 0.0122373 |
| GLUL | glutamate-ammonia ligase | 0.0122081 |
| QSOX1 | quiescin Q6 sulfhydryl oxidase 1 | 0.0120948 |
| GPATCH2L | G patch domain containing 2-like | 0.0119763 |
| LOX | lysyl oxidase | 0.0119557 |
| FAM193B | family with sequence similarity 193, member B | 0.0119541 |
| HYOU1 | hypoxia up-regulated 1 | 0.0118833 |
| LRRC23 | leucine rich repeat containing 23 | 0.0117968 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | 0.0117154 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0116839 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0116487 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0114062 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0113767 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0113584 |
| SSR1 | signal sequence receptor, alpha | 0.011317 |
| TUFT1 | tuftelin 1 | 0.0112685 |
| ABR | active BCR-related | 0.0112588 |
| SCFD2 | sec1 family domain containing 2 | 0.0112033 |
| RASAL2 | RAS protein activator like 2 | 0.0111933 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | 0.011084 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0110162 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0109905 |
| EGR1 | early growth response 1 | 0.0108949 |
| CLIC4 | chloride intracellular channel 4 | 0.0108284 |
| ZHX2 | zinc fingers and homeoboxes 2 | 0.0108057 |
| POU2F2 | POU class 2 homeobox 2 | 0.0107674 |
| SHC3 | SHC (Src homology 2 domain containing) transforming protein 3 | 0.0107557 |
| GJA1 | gap junction protein, alpha 1, 43kDa | 0.0106009 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0105441 |
| MCL1 | myeloid cell leukemia 1 | 0.0105389 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.38519 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.146437 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.116499 |
| MT2A | metallothionein 2A | -0.0722928 |
| CENPF | centromere protein F, 350/400kDa | -0.0688587 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0664981 |
| OSMR | oncostatin M receptor | -0.052431 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0506866 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0488416 |
| FNDC3B | fibronectin type III domain containing 3B | -0.048146 |
| FNBP1 | formin binding protein 1 | -0.0422788 |
| TXNIP | thioredoxin interacting protein | -0.0413011 |
| OGA | O-GlcNAcase | -0.0393293 |
| JMJD1C | jumonji domain containing 1C | -0.0390909 |
| NDRG1 | N-myc downstream regulated 1 | -0.0380372 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0372795 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.036984 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0366889 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0366837 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.0366265 |
| RBM39 | RNA binding motif protein 39 | -0.0348836 |
| CD44 | CD44 molecule (Indian blood group) | -0.0341486 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0336688 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0334099 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0331437 |
| RPS6 | ribosomal protein S6 | -0.0329047 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0318931 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0311406 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0309684 |
| SMAD3 | SMAD family member 3 | -0.0307011 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0306075 |
| IL6ST | interleukin 6 signal transducer | -0.0305404 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0295086 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0292844 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0290391 |
| NEK7 | NIMA-related kinase 7 | -0.028877 |
| TXNRD1 | thioredoxin reductase 1 | -0.0287171 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0286606 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0285909 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | -0.028094 |
| XPO1 | exportin 1 | -0.0279679 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0279456 |
| MCTP2 | multiple C2 domains, transmembrane 2 | -0.027893 |
| SMYD3 | SET and MYND domain containing 3 | -0.0277924 |
| PTK2 | protein tyrosine kinase 2 | -0.0277111 |
| PELO | pelota homolog (Drosophila) | -0.0276802 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0276708 |
| RPL38 | ribosomal protein L38 | -0.0274825 |
| SVIL | supervillin | -0.0271699 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0268756 |
| AHR | aryl hydrocarbon receptor | -0.0266969 |
| CDCP1 | CUB domain containing protein 1 | -0.0266716 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0264861 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0264421 |
| ANLN | anillin, actin binding protein | -0.0263338 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | -0.0261796 |
| MKI67 | marker of proliferation Ki-67 | -0.0261239 |
| FOXP1 | forkhead box P1 | -0.0259387 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0252966 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.025224 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0250251 |
| UBC | ubiquitin C | -0.0249206 |
| SMOX | spermine oxidase | -0.0249175 |
| DUSP5 | dual specificity phosphatase 5 | -0.0244579 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0242953 |
| RPS2 | ribosomal protein S2 | -0.0237409 |
| SPAG9 | sperm associated antigen 9 | -0.0235574 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0235537 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.023499 |
| TMEM156 | transmembrane protein 156 | -0.022874 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0227742 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0226137 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0225397 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | -0.0223919 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0216679 |
| NAV2 | neuron navigator 2 | -0.0215594 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0215149 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0215105 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0214318 |
| IER3 | immediate early response 3 | -0.0211503 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.021126 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0210761 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | -0.0207063 |
| SH3GLB1 | SH3-domain GRB2-like endophilin B1 | -0.0205349 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0204379 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0203859 |
| CAB39 | calcium binding protein 39 | -0.0202876 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0202151 |
| CLTC | clathrin, heavy chain (Hc) | -0.020124 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | -0.019859 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.01982 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0196559 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0195586 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0194641 |
| GOLT1B | golgi transport 1B | -0.0194184 |
| S100A10 | S100 calcium binding protein A10 | -0.0190828 |
| RPS24 | ribosomal protein S24 | -0.0190568 |
| RPS5 | ribosomal protein S5 | -0.0190121 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0188058 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0187592 |
