| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ixazomib citrate perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ixazomib citrate_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SQSTM1 | sequestosome 1 | 0.200373 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0844712 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0810059 |
| GNGT1 | guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 | 0.0601906 |
| TUSC3 | tumor suppressor candidate 3 | 0.0579831 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0530933 |
| DLGAP3 | discs, large (Drosophila) homolog-associated protein 3 | 0.05148 |
| MAP1B | microtubule-associated protein 1B | 0.0479367 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0448138 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0424119 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 0.0419796 |
| PSMD11 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 | 0.0417005 |
| DST | dystonin | 0.0406705 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0402955 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0385204 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0378826 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.037004 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0365883 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0348464 |
| UBR3 | ubiquitin protein ligase E3 component n-recognin 3 (putative) | 0.0347262 |
| HECW1 | HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 | 0.0341317 |
| UBXN4 | UBX domain protein 4 | 0.0337126 |
| CTSB | cathepsin B | 0.0326239 |
| SFTPA2 | surfactant protein A2 | 0.0320354 |
| KIF21A | kinesin family member 21A | 0.0309445 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0308748 |
| SNX29 | sorting nexin 29 | 0.0305263 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0296217 |
| ZFAND5 | zinc finger, AN1-type domain 5 | 0.0286087 |
| NIBAN1 | niban apoptosis regulator 1 | 0.0275068 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | 0.0274414 |
| CEP290 | centrosomal protein 290kDa | 0.0273027 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0266594 |
| DYNC1I1 | dynein, cytoplasmic 1, intermediate chain 1 | 0.0266132 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0257819 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0254333 |
| ASPH | aspartate beta-hydroxylase | 0.0252725 |
| FTL | ferritin, light polypeptide | 0.0249841 |
| TAPBP | TAP binding protein (tapasin) | 0.0247375 |
| METAP1 | methionyl aminopeptidase 1 | 0.0244846 |
| SRGN | serglycin | 0.0243958 |
| FAM219A | family with sequence similarity 219, member A | 0.0236134 |
| MSN | moesin | 0.0233355 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0231727 |
| ABHD3 | abhydrolase domain containing 3 | 0.0227989 |
| CALCOCO2 | calcium binding and coiled-coil domain 2 | 0.0223543 |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) | 0.0222049 |
| ECPAS | Ecm29 proteasome adaptor and scaffold | 0.0218053 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0216408 |
| UBQLN1 | ubiquilin 1 | 0.0215823 |
| ANXA1 | annexin A1 | 0.0211882 |
| PCYT1A | phosphate cytidylyltransferase 1, choline, alpha | 0.0204741 |
| CNBP | CCHC-type zinc finger, nucleic acid binding protein | 0.0194784 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0194097 |
| EIF2AK1 | eukaryotic translation initiation factor 2-alpha kinase 1 | 0.0191601 |
| RND3 | Rho family GTPase 3 | 0.0188527 |
| VCP | valosin containing protein | 0.0186723 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0183362 |
| KIF1B | kinesin family member 1B | 0.0180431 |
| ARPP19 | cAMP-regulated phosphoprotein, 19kDa | 0.0178773 |
| GABPB2 | GA binding protein transcription factor, beta subunit 2 | 0.0178356 |
| TXNRD1 | thioredoxin reductase 1 | 0.0176642 |
| PSMD1 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 | 0.0176518 |
| CLU | clusterin | 0.0176257 |
| PSMD2 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 | 0.0174795 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.017302 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0170284 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.0168971 |
| TPM3 | tropomyosin 3 | 0.0168586 |
| SLMAP | sarcolemma associated protein | 0.0168535 |
| NFASC | neurofascin | 0.0166815 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0166808 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0164921 |
| KIAA1217 | KIAA1217 | 0.0164584 |
| SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) | 0.0164378 |
| VMP1 | vacuole membrane protein 1 | 0.016246 |
| NCKAP1 | NCK-associated protein 1 | 0.016242 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0160995 |
| NMT1 | N-myristoyltransferase 1 | 0.0156096 |
| SPART | spartin | 0.0154084 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0153981 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0150737 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0150241 |
| RABEP1 | rabaptin, RAB GTPase binding effector protein 1 | 0.0149256 |
| CAMSAP1 | calmodulin regulated spectrin-associated protein 1 | 0.0148808 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0148734 |
| USP9Y | ubiquitin specific peptidase 9, Y-linked | 0.0145931 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0144328 |
| PIR | pirin (iron-binding nuclear protein) | 0.0143454 |
| SYT12 | synaptotagmin XII | 0.014241 |
| DNAJC2 | DnaJ (Hsp40) homolog, subfamily C, member 2 | 0.0141985 |
| MORC3 | MORC family CW-type zinc finger 3 | 0.013852 |
| DNTTIP2 | deoxynucleotidyltransferase, terminal, interacting protein 2 | 0.0138113 |
| ATP6V1A | ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A | 0.0136552 |
| RANBP2 | RAN binding protein 2 | 0.0134918 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0134648 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0134188 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.013256 |
| NXPE3 | neurexophilin and PC-esterase domain family, member 3 | 0.0131757 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | 0.0131529 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.31884 |
| VIM | vimentin | -0.192694 |
| TMSB10 | thymosin beta 10 | -0.192468 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.1633 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.161357 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.133413 |
| MT2A | metallothionein 2A | -0.107992 |
| NAV1 | neuron navigator 1 | -0.0854176 |
| LOX | lysyl oxidase | -0.0796629 |
| S100A10 | S100 calcium binding protein A10 | -0.0777571 |
| POTEF | POTE ankyrin domain family, member F | -0.0714888 |
| PLAT | plasminogen activator, tissue | -0.0683952 |
| COL5A2 | collagen, type V, alpha 2 | -0.0681768 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0640234 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0621771 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0612226 |
| SUCNR1 | succinate receptor 1 | -0.0585401 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0567001 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | -0.0563095 |
| COL1A2 | collagen, type I, alpha 2 | -0.0500879 |
| TAGLN2 | transgelin 2 | -0.0500169 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0498785 |
| FBN1 | fibrillin 1 | -0.0487136 |
| S100A6 | S100 calcium binding protein A6 | -0.0486472 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.047802 |
| PRELID2 | PRELI domain containing 2 | -0.0465818 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0458171 |
| MEIS2 | Meis homeobox 2 | -0.045202 |
| PKM | pyruvate kinase, muscle | -0.0445631 |
| THBS2 | thrombospondin 2 | -0.0438336 |
| ANXA2 | annexin A2 | -0.0436069 |
| CDH13 | cadherin 13 | -0.0424989 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.0413169 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0410458 |
| NDRG1 | N-myc downstream regulated 1 | -0.0406671 |
| AUTS2 | autism susceptibility candidate 2 | -0.0400801 |
| LMNA | lamin A/C | -0.0400151 |
| CCND1 | cyclin D1 | -0.0392885 |
| HLA-C | major histocompatibility complex, class I, C | -0.0389902 |
| MX2 | MX dynamin-like GTPase 2 | -0.0389559 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0375923 |
| ACTG1 | actin gamma 1 | -0.0369518 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0368625 |
| PTMA | prothymosin, alpha | -0.0360233 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0358523 |
| PODXL | podocalyxin-like | -0.0354684 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0347117 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0345599 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.034327 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0338476 |
| SMYD3 | SET and MYND domain containing 3 | -0.033597 |
| MYOF | myoferlin | -0.033542 |
| HLA-B | major histocompatibility complex, class I, B | -0.0334937 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0334503 |
| DCLK2 | doublecortin-like kinase 2 | -0.033282 |
| LOXL2 | lysyl oxidase-like 2 | -0.0327118 |
| GNAS | GNAS complex locus | -0.032398 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0314454 |
| DPYSL3 | dihydropyrimidinase-like 3 | -0.0314087 |
| TPM1 | tropomyosin 1 (alpha) | -0.0313446 |
| SP3 | Sp3 transcription factor | -0.031275 |
| RNF213 | ring finger protein 213 | -0.0310906 |
| CUX1 | cut-like homeobox 1 | -0.0310443 |
| RRBP1 | ribosome binding protein 1 | -0.0307859 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0305059 |
| MYADM | myeloid-associated differentiation marker | -0.0302287 |
| COL5A1 | collagen, type V, alpha 1 | -0.0295684 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0294641 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0292153 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0290693 |
| RUNX1 | runt-related transcription factor 1 | -0.0288685 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.0288411 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0287407 |
| MSI2 | musashi RNA-binding protein 2 | -0.0285227 |
| GNB4 | guanine nucleotide binding protein (G protein), beta polypeptide 4 | -0.0282855 |
| KIFAP3 | kinesin-associated protein 3 | -0.0282825 |
| FRMD4A | FERM domain containing 4A | -0.0282805 |
| S100A4 | S100 calcium binding protein A4 | -0.0282185 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0282134 |
| HS3ST3A1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 | -0.0271975 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | -0.0269272 |
| PARD3 | par-3 family cell polarity regulator | -0.0268569 |
| CAVIN1 | caveolae associated protein 1 | -0.0267835 |
| DPYSL2 | dihydropyrimidinase-like 2 | -0.0267208 |
| RPS24 | ribosomal protein S24 | -0.0264939 |
| ZNF207 | zinc finger protein 207 | -0.026397 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0263965 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0260262 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0259767 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0258509 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0258216 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0256431 |
| OGA | O-GlcNAcase | -0.0256124 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0256081 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.0255558 |
| RPL28 | ribosomal protein L28 | -0.0255256 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0254094 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | -0.0253929 |
| GLIS3 | GLIS family zinc finger 3 | -0.0252961 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0249415 |
