| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ixazomib citrate perturbation in BT-474 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ixazomib citrate_BT-474 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FTH1 | ferritin, heavy polypeptide 1 | 0.0448527 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0384955 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.0372232 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0269747 |
| MT2A | metallothionein 2A | 0.0254431 |
| ACSS2 | acyl-CoA synthetase short-chain family member 2 | 0.0237694 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | 0.0231781 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0225417 |
| SERPINB3 | serpin peptidase inhibitor, clade B (ovalbumin), member 3 | 0.0217591 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0215504 |
| SERPINB4 | serpin peptidase inhibitor, clade B (ovalbumin), member 4 | 0.0201705 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.0192616 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0191192 |
| EZR | ezrin | 0.0178804 |
| SDC4 | syndecan 4 | 0.0178542 |
| TMEM45B | transmembrane protein 45B | 0.0178434 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.0174809 |
| TMEM165 | transmembrane protein 165 | 0.0174755 |
| S100A8 | S100 calcium binding protein A8 | 0.0174412 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0170005 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.0168923 |
| TAPBP | TAP binding protein (tapasin) | 0.0163278 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0161869 |
| CFB | complement factor B | 0.015673 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.015506 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0152198 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0150011 |
| SQLE | squalene epoxidase | 0.0149746 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | 0.0148052 |
| S100A14 | S100 calcium binding protein A14 | 0.0147203 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0138663 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0137446 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0135324 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0133188 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0123607 |
| MAP1B | microtubule-associated protein 1B | 0.0123299 |
| ZFP36 | ZFP36 ring finger protein | 0.0123267 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0122465 |
| CD59 | CD59 molecule, complement regulatory protein | 0.0120677 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0120422 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0119907 |
| MSMO1 | methylsterol monooxygenase 1 | 0.0117379 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0117376 |
| MLPH | melanophilin | 0.0115524 |
| VEGFA | vascular endothelial growth factor A | 0.0114509 |
| BRD2 | bromodomain containing 2 | 0.0114395 |
| PPP1R9B | protein phosphatase 1, regulatory subunit 9B | 0.011283 |
| EGFR | epidermal growth factor receptor | 0.0112316 |
| ANXA5 | annexin A5 | 0.011118 |
| TOP6BL | TOP6B like initiator of meiotic double strand breaks | 0.010983 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.0107484 |
| ABHD17C | abhydrolase domain containing 17C | 0.0104234 |
| PDCD4 | programmed cell death 4 (neoplastic transformation inhibitor) | 0.0103867 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0103703 |
| KIF16B | kinesin family member 16B | 0.0100225 |
| TAB3 | TGF-beta activated kinase 1/MAP3K7 binding protein 3 | 0.0100095 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.00986237 |
| SLK | STE20-like kinase | 0.00985275 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.00978666 |
| FBXO32 | F-box protein 32 | 0.00967511 |
| NDRG1 | N-myc downstream regulated 1 | 0.00949919 |
| FDFT1 | farnesyl-diphosphate farnesyltransferase 1 | 0.00943583 |
| SMAD3 | SMAD family member 3 | 0.00929769 |
| INSIG1 | insulin induced gene 1 | 0.00921895 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.00918483 |
| GBP2 | guanylate binding protein 2, interferon-inducible | 0.00917255 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | 0.0091147 |
| DSCAM | Down syndrome cell adhesion molecule | 0.00907286 |
| PDLIM5 | PDZ and LIM domain 5 | 0.00888892 |
| AREG | amphiregulin | 0.00883883 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.00875698 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | 0.00873921 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | 0.00871258 |
| FRY | furry homolog (Drosophila) | 0.00863529 |
| FAM13A | family with sequence similarity 13, member A | 0.00862549 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.00857502 |
| CCNG2 | cyclin G2 | 0.00851939 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.00839199 |
| SAMD5 | sterile alpha motif domain containing 5 | 0.00830731 |
| TNIK | TRAF2 and NCK interacting kinase | 0.00829942 |
| RND3 | Rho family GTPase 3 | 0.00821454 |
| RBM12 | RNA binding motif protein 12 | 0.00810863 |
| WASL | Wiskott-Aldrich syndrome-like | 0.00802111 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.00801939 |
| SLC22A23 | solute carrier family 22, member 23 | 0.00794153 |
| CNTNAP2 | contactin associated protein-like 2 | 0.00791014 |
| SFTPA2 | surfactant protein A2 | 0.00786453 |
| KDM7A | lysine (K)-specific demethylase 7A | 0.00784199 |
| IDI1 | isopentenyl-diphosphate delta isomerase 1 | 0.0077575 |
| BCL9L | B-cell CLL/lymphoma 9-like | 0.00772402 |
| ATP11B | ATPase, class VI, type 11B | 0.00761269 |
| SECISBP2L | SECIS binding protein 2-like | 0.00760725 |
| STK17A | serine/threonine kinase 17a | 0.00759452 |
| ADM | adrenomedullin | 0.00758351 |
| ANKRD36C | ankyrin repeat domain 36C | 0.0075119 |
| NIBAN2 | niban apoptosis regulator 2 | 0.00743494 |
| LMO7 | LIM domain 7 | 0.00734621 |
| PDZD8 | PDZ domain containing 8 | 0.00725569 |
| NCKAP1 | NCK-associated protein 1 | 0.00725156 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0072276 |
| Symbol | Name | Standardized Value |
|---|---|---|
| RPL19 | ribosomal protein L19 | -0.237768 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.234219 |
| RPL23 | ribosomal protein L23 | -0.211942 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.120305 |
| CDK12 | cyclin-dependent kinase 12 | -0.0973004 |
| ACACA | acetyl-CoA carboxylase alpha | -0.0950645 |
| CATSPERB | catsper channel auxiliary subunit beta | -0.0652754 |
| PTK2 | protein tyrosine kinase 2 | -0.0624064 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | -0.0580657 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.055444 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0546752 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0540125 |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 | -0.0529493 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0516226 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0516065 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0512903 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0503635 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0498638 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0493026 |
| ACTG1 | actin gamma 1 | -0.0491026 |
| PRRC2B | proline-rich coiled-coil 2B | -0.0490896 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0477492 |
| NCOA3 | nuclear receptor coactivator 3 | -0.0468933 |
| ENAH | enabled homolog (Drosophila) | -0.0468403 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0464116 |
| TMEM123 | transmembrane protein 123 | -0.0451028 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0445533 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0442296 |
| NCOA6 | nuclear receptor coactivator 6 | -0.0434866 |
| SP100 | SP100 nuclear antigen | -0.0431606 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0429303 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.04266 |
| PTMA | prothymosin, alpha | -0.0420541 |
| DTNA | dystrobrevin, alpha | -0.0395218 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0393158 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0391651 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0383314 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.038025 |
| RPL35A | ribosomal protein L35a | -0.0376896 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0368467 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0366651 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0365563 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | -0.0360635 |
| LASP1 | LIM and SH3 protein 1 | -0.0357027 |
| UBC | ubiquitin C | -0.0355129 |
| RAB22A | RAB22A, member RAS oncogene family | -0.035213 |
| DENND1A | DENN/MADD domain containing 1A | -0.0351517 |
| PARD3 | par-3 family cell polarity regulator | -0.0349773 |
| CEP250 | centrosomal protein 250kDa | -0.0348913 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0348745 |
| EFNA5 | ephrin-A5 | -0.0344617 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0343408 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0336595 |
| MLLT6 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6 | -0.0336266 |
| CREB5 | cAMP responsive element binding protein 5 | -0.0325325 |
| NF1 | neurofibromin 1 | -0.0320199 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0314423 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0307084 |
| TMSB4X | thymosin beta 4, X-linked | -0.0301529 |
| ZNF207 | zinc finger protein 207 | -0.0299025 |
| JMJD1C | jumonji domain containing 1C | -0.0298909 |
| RPL37A | ribosomal protein L37a | -0.0297524 |
| RBM47 | RNA binding motif protein 47 | -0.0296552 |
| CCND1 | cyclin D1 | -0.0296402 |
| VCP | valosin containing protein | -0.0295854 |
| CUX1 | cut-like homeobox 1 | -0.0289757 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0287556 |
| RPL12 | ribosomal protein L12 | -0.0287539 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0284121 |
| PBX1 | pre-B-cell leukemia homeobox 1 | -0.0282327 |
| PLSCR1 | phospholipid scramblase 1 | -0.0281559 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.0280423 |
| RABGAP1 | RAB GTPase activating protein 1 | -0.028011 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0278657 |
| LARGE1 | LARGE xylosyl- and glucuronyltransferase 1 | -0.0274554 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0273563 |
| MIPOL1 | mirror-image polydactyly 1 | -0.0273287 |
| MBD4 | methyl-CpG binding domain protein 4 | -0.0269566 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0268158 |
| KIAA1217 | KIAA1217 | -0.0267047 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0265355 |
| MSI2 | musashi RNA-binding protein 2 | -0.0265178 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | -0.0264616 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | -0.0262595 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.026072 |
| TMSB10 | thymosin beta 10 | -0.0260047 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0259791 |
| HLA-C | major histocompatibility complex, class I, C | -0.0257955 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0256229 |
| RPS24 | ribosomal protein S24 | -0.0256029 |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) | -0.0254426 |
| UQCC1 | ubiquinol-cytochrome c reductase complex assembly factor 1 | -0.0254013 |
| EXOC4 | exocyst complex component 4 | -0.0253832 |
| SBF2 | SET binding factor 2 | -0.0253505 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0252626 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0250663 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0249435 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0248789 |
| EHMT1 | euchromatic histone-lysine N-methyltransferase 1 | -0.024816 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0247614 |
