| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ixazomib citrate perturbation in C32 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ixazomib citrate_C32 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | 0.0572895 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.040081 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0398389 |
| PI15 | peptidase inhibitor 15 | 0.0390854 |
| VMP1 | vacuole membrane protein 1 | 0.0336834 |
| TMEM178B | transmembrane protein 178B | 0.0322062 |
| RTN4 | reticulon 4 | 0.031675 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0298187 |
| MRTFA | myocardin related transcription factor A | 0.0295142 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0291817 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0284334 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0273999 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0267905 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0265677 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0247423 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0231857 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0230964 |
| RBM33 | RNA binding motif protein 33 | 0.0230638 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0229629 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0224927 |
| RNF145 | ring finger protein 145 | 0.0220641 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0219409 |
| VCL | vinculin | 0.0203595 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.0194423 |
| APP | amyloid beta (A4) precursor protein | 0.0193611 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0191722 |
| ICAM1 | intercellular adhesion molecule 1 | 0.0191655 |
| CDC73 | cell division cycle 73 | 0.018871 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0187218 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0186176 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0183904 |
| WASL | Wiskott-Aldrich syndrome-like | 0.0183174 |
| ARRDC3 | arrestin domain containing 3 | 0.0182117 |
| FBXO7 | F-box protein 7 | 0.0181371 |
| CUL3 | cullin 3 | 0.0177616 |
| CCNL1 | cyclin L1 | 0.0177062 |
| ZNF654 | zinc finger protein 654 | 0.0176073 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0176071 |
| AFDN | afadin, adherens junction formation factor | 0.0176069 |
| WDR43 | WD repeat domain 43 | 0.0175028 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0173685 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0173301 |
| MSN | moesin | 0.0169838 |
| MT1X | metallothionein 1X | 0.0169207 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0167212 |
| MED13L | mediator complex subunit 13-like | 0.0166667 |
| ZYX | zyxin | 0.0165897 |
| TAPBP | TAP binding protein (tapasin) | 0.0164882 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | 0.0162235 |
| LEF1 | lymphoid enhancer-binding factor 1 | 0.0158144 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0154495 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0154396 |
| NEK7 | NIMA-related kinase 7 | 0.0153487 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0152827 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | 0.015098 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0150629 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0149178 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.014627 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0145445 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0144503 |
| TRIB1 | tribbles pseudokinase 1 | 0.0143926 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0143098 |
| AHR | aryl hydrocarbon receptor | 0.0142583 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0142423 |
| IL6ST | interleukin 6 signal transducer | 0.013917 |
| SERINC1 | serine incorporator 1 | 0.0135579 |
| WBP11 | WW domain binding protein 11 | 0.0134289 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | 0.0132799 |
| UGP2 | UDP-glucose pyrophosphorylase 2 | 0.0132714 |
| TPR | translocated promoter region, nuclear basket protein | 0.0132514 |
| HIPK3 | homeodomain interacting protein kinase 3 | 0.0131837 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0130944 |
| RGS2 | regulator of G-protein signaling 2 | 0.0130064 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.0128459 |
| RHOJ | ras homolog family member J | 0.0127846 |
| PPME1 | protein phosphatase methylesterase 1 | 0.0126096 |
| TOP1 | topoisomerase (DNA) I | 0.0125568 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0124109 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | 0.0124106 |
| GBP2 | guanylate binding protein 2, interferon-inducible | 0.0123645 |
| BCL6 | B-cell CLL/lymphoma 6 | 0.0123426 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0123347 |
| CORO1C | coronin, actin binding protein, 1C | 0.0123035 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0122175 |
| PXMP2 | peroxisomal membrane protein 2, 22kDa | 0.0122091 |
| FAM3C | family with sequence similarity 3, member C | 0.0121373 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0121356 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0120834 |
| MATR3 | matrin 3 | 0.0120377 |
| BRD2 | bromodomain containing 2 | 0.0120072 |
| FERMT2 | fermitin family member 2 | 0.011938 |
| RYK | receptor-like tyrosine kinase | 0.0119274 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0117825 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0113318 |
| MIDEAS | mitotic deacetylase associated SANT domain protein | 0.0112655 |
| HBP1 | HMG-box transcription factor 1 | 0.0112286 |
| PUM1 | pumilio RNA-binding family member 1 | 0.011221 |
| YBX3 | Y box binding protein 3 | 0.0111991 |
| MTERF1 | mitochondrial transcription termination factor 1 | 0.0111966 |
| SLK | STE20-like kinase | 0.0111946 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.262873 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.257454 |
| FN1 | fibronectin 1 | -0.198432 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.187093 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.17328 |
| NLGN1 | neuroligin 1 | -0.168236 |
| GPC6 | glypican 6 | -0.168206 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.142775 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.100991 |
| VGF | VGF nerve growth factor inducible | -0.0891474 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0824121 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | -0.0751689 |
| NPAS2 | neuronal PAS domain protein 2 | -0.073294 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0677769 |
| NDRG1 | N-myc downstream regulated 1 | -0.0652458 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0625162 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0623803 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0621339 |
| VIM | vimentin | -0.0596418 |
| EHBP1 | EH domain binding protein 1 | -0.0595601 |
| SCFD2 | sec1 family domain containing 2 | -0.0594924 |
| NAV3 | neuron navigator 3 | -0.0593128 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0592959 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.056743 |
| MACROD2 | MACRO domain containing 2 | -0.0551722 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0550098 |
| CUX1 | cut-like homeobox 1 | -0.0529356 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0525723 |
| PTK2 | protein tyrosine kinase 2 | -0.0518253 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0516991 |
| NBAS | neuroblastoma amplified sequence | -0.050736 |
| FRMD4A | FERM domain containing 4A | -0.0491536 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0490334 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0485151 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | -0.0484416 |
| GDF15 | growth differentiation factor 15 | -0.0479528 |
| ENO1 | enolase 1, (alpha) | -0.0474696 |
| CTTNBP2 | cortactin binding protein 2 | -0.0472819 |
| RUNX1 | runt-related transcription factor 1 | -0.0465422 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0459572 |
| CALU | calumenin | -0.0456513 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0450754 |
| TMEM123 | transmembrane protein 123 | -0.0440719 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0438656 |
| CALR | calreticulin | -0.043132 |
| CDK14 | cyclin-dependent kinase 14 | -0.0431022 |
| HLA-B | major histocompatibility complex, class I, B | -0.0428702 |
| TAC4 | tachykinin 4 (hemokinin) | -0.0426563 |
| HMCN1 | hemicentin 1 | -0.0423886 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0419587 |
| TRIM2 | tripartite motif containing 2 | -0.0419381 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0412573 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0402029 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0396669 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0396333 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0394051 |
| OXR1 | oxidation resistance 1 | -0.0392672 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0390044 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0388358 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0376063 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0367677 |
| DCT | dopachrome tautomerase | -0.0366598 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | -0.0364076 |
| KIRREL1 | kirre like nephrin family adhesion molecule 1 | -0.0360794 |
| CD109 | CD109 molecule | -0.0359834 |
| HMGA2 | high mobility group AT-hook 2 | -0.0358077 |
| MMP16 | matrix metallopeptidase 16 (membrane-inserted) | -0.0357186 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.0354249 |
| COL19A1 | collagen, type XIX, alpha 1 | -0.0353277 |
| CANX | calnexin | -0.0353141 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0351997 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0350965 |
| TNFRSF19 | tumor necrosis factor receptor superfamily, member 19 | -0.0347889 |
| ZNF704 | zinc finger protein 704 | -0.0347865 |
| FHIT | fragile histidine triad | -0.0344943 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0342998 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0342629 |
| TMSB10 | thymosin beta 10 | -0.0336649 |
| NEGR1 | neuronal growth regulator 1 | -0.0334491 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0329341 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0329202 |
| S100A6 | S100 calcium binding protein A6 | -0.0324151 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0321982 |
| TULP4 | tubby like protein 4 | -0.0319955 |
| LSAMP | limbic system-associated membrane protein | -0.031774 |
| PLIN2 | perilipin 2 | -0.0314797 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0309844 |
| RNF24 | ring finger protein 24 | -0.030851 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0304911 |
| NRCAM | neuronal cell adhesion molecule | -0.0302777 |
| LARGE1 | LARGE xylosyl- and glucuronyltransferase 1 | -0.0289037 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.0283858 |
| EBF1 | early B-cell factor 1 | -0.0274883 |
| PDE10A | phosphodiesterase 10A | -0.026608 |
| FMNL2 | formin-like 2 | -0.0264281 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0263227 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0260964 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0258203 |
| AHCYL2 | adenosylhomocysteinase-like 2 | -0.0255303 |
| LAMB1 | laminin, beta 1 | -0.0255102 |
