| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ixazomib citrate perturbation in CFPAC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Ixazomib citrate_CFPAC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | 0.154019 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0960861 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.077207 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0758364 |
| MT1X | metallothionein 1X | 0.0745621 |
| PTMA | prothymosin, alpha | 0.0687949 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.06447 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0583268 |
| ARRDC3 | arrestin domain containing 3 | 0.0521448 |
| BRD2 | bromodomain containing 2 | 0.0447763 |
| MAP1B | microtubule-associated protein 1B | 0.0438075 |
| TXNRD1 | thioredoxin reductase 1 | 0.0437645 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0427859 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0426845 |
| ASPH | aspartate beta-hydroxylase | 0.0422862 |
| APP | amyloid beta (A4) precursor protein | 0.0418032 |
| KLF6 | Kruppel-like factor 6 | 0.0407091 |
| SFTPA2 | surfactant protein A2 | 0.0392687 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0367799 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.036203 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0361822 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0360092 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0350135 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0332609 |
| KIF5B | kinesin family member 5B | 0.0324372 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0322288 |
| RBM25 | RNA binding motif protein 25 | 0.0313247 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0308367 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0304714 |
| SMAD3 | SMAD family member 3 | 0.0304366 |
| TMSB4X | thymosin beta 4, X-linked | 0.0302914 |
| PLAUR | plasminogen activator, urokinase receptor | 0.029768 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | 0.0294738 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0292949 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0292562 |
| VMP1 | vacuole membrane protein 1 | 0.0287916 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0285357 |
| RPS3 | ribosomal protein S3 | 0.0282288 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0277575 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0276798 |
| PSMC6 | proteasome (prosome, macropain) 26S subunit, ATPase, 6 | 0.0274336 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0269468 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0268297 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0268095 |
| MKI67 | marker of proliferation Ki-67 | 0.0258875 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0255485 |
| CORO1C | coronin, actin binding protein, 1C | 0.0254569 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0248269 |
| AREG | amphiregulin | 0.0239878 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0239003 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0238708 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0238236 |
| B2M | beta-2-microglobulin | 0.0238232 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0236762 |
| RIOK3 | RIO kinase 3 | 0.0233988 |
| ADM | adrenomedullin | 0.0228025 |
| FDPS | farnesyl diphosphate synthase | 0.0221095 |
| TUSC3 | tumor suppressor candidate 3 | 0.0218638 |
| MORC3 | MORC family CW-type zinc finger 3 | 0.0216311 |
| NCKAP1 | NCK-associated protein 1 | 0.0212486 |
| RBM39 | RNA binding motif protein 39 | 0.021205 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0211133 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0211061 |
| ANKRD11 | ankyrin repeat domain 11 | 0.02106 |
| PNN | pinin, desmosome associated protein | 0.020967 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0208824 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0207212 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0206833 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0206501 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0202824 |
| TPM3 | tropomyosin 3 | 0.0198854 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.019855 |
| FUBP1 | far upstream element (FUSE) binding protein 1 | 0.0196489 |
| LAMB3 | laminin, beta 3 | 0.0195172 |
| APOL1 | apolipoprotein L, 1 | 0.0193946 |
| ARPP19 | cAMP-regulated phosphoprotein, 19kDa | 0.0191969 |
| SERINC1 | serine incorporator 1 | 0.0191898 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0190003 |
| CCNY | cyclin Y | 0.0189992 |
| HPCAL1 | hippocalcin-like 1 | 0.0189073 |
| TPR | translocated promoter region, nuclear basket protein | 0.0188341 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0186272 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | 0.0186203 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 0.0184109 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 | 0.0183506 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0179826 |
| PSMD1 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 | 0.0175463 |
| PGK1 | phosphoglycerate kinase 1 | 0.0175057 |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 | 0.0174739 |
| EZR | ezrin | 0.017398 |
| OGA | O-GlcNAcase | 0.0173408 |
| MATR3 | matrin 3 | 0.0173306 |
| FAM110C | family with sequence similarity 110, member C | 0.017275 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0172158 |
| GOLGA4 | golgin A4 | 0.0171899 |
| ABTB3 | ankyrin repeat and BTB domain containing 3 | 0.0171211 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0167528 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0167437 |
| PRR11 | proline rich 11 | 0.016562 |
| CANX | calnexin | 0.0164923 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.151648 |
| FNDC3B | fibronectin type III domain containing 3B | -0.149966 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.116883 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.100062 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0984324 |
| MMP7 | matrix metallopeptidase 7 | -0.0930092 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0929939 |
| EFNA5 | ephrin-A5 | -0.0927162 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0905294 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0891977 |
| HMGA1 | high mobility group AT-hook 1 | -0.0838673 |
| LMO7 | LIM domain 7 | -0.0802214 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0799322 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0794168 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0775156 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0761561 |
| DTNA | dystrobrevin, alpha | -0.0709321 |
| FTL | ferritin, light polypeptide | -0.0651001 |
| PKM | pyruvate kinase, muscle | -0.0644602 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0596887 |
| RAD51B | RAD51 paralog B | -0.0588251 |
| OSMR | oncostatin M receptor | -0.058 |
| RNF213 | ring finger protein 213 | -0.0578902 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0571251 |
| CD2AP | CD2-associated protein | -0.0548075 |
| EHBP1 | EH domain binding protein 1 | -0.0545695 |
| MYO1E | myosin IE | -0.0539816 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0532591 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | -0.0527413 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0520618 |
| BICC1 | BicC family RNA binding protein 1 | -0.0515701 |
| CP | ceruloplasmin (ferroxidase) | -0.0494387 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0491086 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0488163 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0485303 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0483755 |
| TMSB10 | thymosin beta 10 | -0.0462053 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0458325 |
| MX1 | MX dynamin-like GTPase 1 | -0.0450441 |
| PRKCA | protein kinase C, alpha | -0.0449074 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0431003 |
| PARD3 | par-3 family cell polarity regulator | -0.0429772 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0427424 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0426879 |
| MEF2A | myocyte enhancer factor 2A | -0.0409404 |
| MUC16 | mucin 16, cell surface associated | -0.0408999 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.0408794 |
| NRP1 | neuropilin 1 | -0.0408789 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0405371 |
| RPL23 | ribosomal protein L23 | -0.0397753 |
| EGR1 | early growth response 1 | -0.0397722 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0390404 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0386735 |
| NRG3 | neuregulin 3 | -0.0383268 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0372536 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0372132 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0369644 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0366298 |
| MUC4 | mucin 4, cell surface associated | -0.0357576 |
| JUP | junction plakoglobin | -0.0355651 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0355127 |
| HLA-A | major histocompatibility complex, class I, A | -0.0352562 |
| SGMS2 | sphingomyelin synthase 2 | -0.0351688 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0349582 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0347644 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0342846 |
| MX2 | MX dynamin-like GTPase 2 | -0.0341727 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0339611 |
| TJP1 | tight junction protein 1 | -0.0334849 |
| RIN2 | Ras and Rab interactor 2 | -0.0333214 |
| ANXA2 | annexin A2 | -0.0332719 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | -0.0332385 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0329263 |
| ITGB8 | integrin, beta 8 | -0.0328851 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0327502 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0321081 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | -0.0320049 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.031768 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0317201 |
| FBXO11 | F-box protein 11 | -0.0317066 |
| S100A6 | S100 calcium binding protein A6 | -0.0315145 |
| SEC24A | SEC24 family member A | -0.0307403 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0306106 |
| ITGB4 | integrin, beta 4 | -0.0305613 |
| MACC1 | metastasis associated in colon cancer 1 | -0.0303762 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0303079 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0301256 |
| NCKAP5 | NCK-associated protein 5 | -0.0297219 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.029654 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0295896 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.029552 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0295289 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0294269 |
| LAMA5 | laminin, alpha 5 | -0.0293556 |
| TGM2 | transglutaminase 2 | -0.0293343 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0292234 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0290001 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0284338 |
| ITGA1 | integrin, alpha 1 | -0.028316 |
| NUMB | numb homolog (Drosophila) | -0.0282343 |
