| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ixazomib citrate perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Ixazomib citrate_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.114183 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | 0.0930535 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0930158 |
| MAP1B | microtubule-associated protein 1B | 0.0750595 |
| DST | dystonin | 0.0695553 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0648901 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0615891 |
| LPIN1 | lipin 1 | 0.0609553 |
| FMN1 | formin 1 | 0.0602615 |
| CRH | corticotropin releasing hormone | 0.0535335 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0525173 |
| DLC1 | DLC1 Rho GTPase activating protein | 0.0490065 |
| NCAM2 | neural cell adhesion molecule 2 | 0.0488985 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0474884 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0459034 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | 0.0425929 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0408465 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | 0.0403559 |
| TPST1 | tyrosylprotein sulfotransferase 1 | 0.0397432 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0394369 |
| TLE4 | transducin-like enhancer of split 4 | 0.0385546 |
| SYT1 | synaptotagmin I | 0.037943 |
| PRKD1 | protein kinase D1 | 0.0363959 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | 0.0355233 |
| PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) | 0.0339738 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 | 0.0339025 |
| HMBOX1 | homeobox containing 1 | 0.0335561 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.032961 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0323633 |
| RPL19 | ribosomal protein L19 | 0.031904 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | 0.0316715 |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase | 0.0311135 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0304666 |
| COL3A1 | collagen, type III, alpha 1 | 0.0303761 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | 0.030372 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0303135 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0296561 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0291583 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0289353 |
| ANGPT1 | angiopoietin 1 | 0.0289052 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0285565 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0282557 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | 0.0276338 |
| XPR1 | xenotropic and polytropic retrovirus receptor 1 | 0.0270784 |
| KLF6 | Kruppel-like factor 6 | 0.0270073 |
| RAB21 | RAB21, member RAS oncogene family | 0.0269406 |
| PCDH9 | protocadherin 9 | 0.0266544 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.0262574 |
| CAMSAP2 | calmodulin regulated spectrin-associated protein family, member 2 | 0.0258436 |
| VMP1 | vacuole membrane protein 1 | 0.0258066 |
| TMEM108 | transmembrane protein 108 | 0.025522 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | 0.0252084 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0251853 |
| VGF | VGF nerve growth factor inducible | 0.0250241 |
| SBNO1 | strawberry notch homolog 1 (Drosophila) | 0.0247532 |
| CD46 | CD46 molecule, complement regulatory protein | 0.024662 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.0241041 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0240552 |
| MYCN | v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog | 0.0238938 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | 0.0238641 |
| SRP9 | signal recognition particle 9kDa | 0.0238115 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0238076 |
| RPS3 | ribosomal protein S3 | 0.0238049 |
| CCNG2 | cyclin G2 | 0.0235734 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.0235405 |
| ATRNL1 | attractin-like 1 | 0.0234007 |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 | 0.0231927 |
| DDX50 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 50 | 0.0231896 |
| SNRNP200 | small nuclear ribonucleoprotein 200kDa (U5) | 0.0231884 |
| ECPAS | Ecm29 proteasome adaptor and scaffold | 0.0231807 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0230546 |
| MORF4L1 | mortality factor 4 like 1 | 0.0225296 |
| UBC | ubiquitin C | 0.0224985 |
| PHOX2B | paired-like homeobox 2b | 0.0224228 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0223908 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0223699 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | 0.0222781 |
| SH3BP5 | SH3-domain binding protein 5 (BTK-associated) | 0.0222505 |
| DKK2 | dickkopf WNT signaling pathway inhibitor 2 | 0.0222387 |
| PRPF3 | pre-mRNA processing factor 3 | 0.0222313 |
| SLC2A13 | solute carrier family 2 (facilitated glucose transporter), member 13 | 0.0222274 |
| SCG2 | secretogranin II | 0.0221375 |
| CEP290 | centrosomal protein 290kDa | 0.0221313 |
| TBL1X | transducin (beta)-like 1X-linked | 0.0221281 |
| TBC1D4 | TBC1 domain family, member 4 | 0.0221147 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | 0.0220837 |
| HADHA | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit | 0.0220413 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0220232 |
| EWSR1 | EWS RNA-binding protein 1 | 0.021805 |
| SIK2 | salt-inducible kinase 2 | 0.0215766 |
| ARHGAP24 | Rho GTPase activating protein 24 | 0.0214581 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0214238 |
| PTCHD1 | patched domain containing 1 | 0.021361 |
| SET | SET nuclear proto-oncogene | 0.0211413 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.0211411 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 | 0.0209277 |
| TRIM9 | tripartite motif containing 9 | 0.0208635 |
| RPL23 | ribosomal protein L23 | 0.0208171 |
| PCM1 | pericentriolar material 1 | 0.0207361 |
| FGF14 | fibroblast growth factor 14 | 0.0207044 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.164141 |
| IGF2 | insulin-like growth factor 2 | -0.159073 |
| NRG1 | neuregulin 1 | -0.142708 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.125598 |
| VIM | vimentin | -0.0953579 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.083455 |
| FN1 | fibronectin 1 | -0.0752612 |
| NDRG1 | N-myc downstream regulated 1 | -0.0736868 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0715212 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0707444 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0660402 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0647616 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.062774 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0566036 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0547742 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0541079 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0537058 |
| RPLP1 | ribosomal protein, large, P1 | -0.0535287 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.053482 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0528426 |
| USP34 | ubiquitin specific peptidase 34 | -0.0495575 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0488926 |
| MEF2A | myocyte enhancer factor 2A | -0.0485372 |
| HMGA2 | high mobility group AT-hook 2 | -0.0485193 |
| MSI2 | musashi RNA-binding protein 2 | -0.0483447 |
| KPNB1 | karyopherin (importin) beta 1 | -0.045873 |
| RPTOR | regulatory associated protein of MTOR, complex 1 | -0.0456693 |
| STC1 | stanniocalcin 1 | -0.0446368 |
| MCL1 | myeloid cell leukemia 1 | -0.0437698 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0434548 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0432879 |
| NFIB | nuclear factor I/B | -0.0432631 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0420715 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0417339 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0416364 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0413662 |
| FLT1 | fms-related tyrosine kinase 1 | -0.0409727 |
| ACTG1 | actin gamma 1 | -0.0403252 |
| CHD9 | chromodomain helicase DNA binding protein 9 | -0.0402774 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0402309 |
| RBM20 | RNA binding motif protein 20 | -0.0401361 |
| CDH13 | cadherin 13 | -0.0399397 |
| RPL38 | ribosomal protein L38 | -0.0398748 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0395121 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0392695 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.038906 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0388825 |
| ZNF638 | zinc finger protein 638 | -0.0387246 |
| TRIM24 | tripartite motif containing 24 | -0.0384543 |
| FKBP1A | FK506 binding protein 1A, 12kDa | -0.0380551 |
| SRPK2 | SRSF protein kinase 2 | -0.0373786 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0365522 |
| EXOC4 | exocyst complex component 4 | -0.035979 |
| IER3 | immediate early response 3 | -0.0356764 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0356228 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0355415 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0355356 |
| HM13 | histocompatibility (minor) 13 | -0.0351504 |
| DTNA | dystrobrevin, alpha | -0.0350288 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -0.0349491 |
| ARF4 | ADP-ribosylation factor 4 | -0.0343787 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0342379 |
| FHIT | fragile histidine triad | -0.0338506 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0337444 |
| TPM1 | tropomyosin 1 (alpha) | -0.0336364 |
| FBXO11 | F-box protein 11 | -0.0335728 |
| CCDC91 | coiled-coil domain containing 91 | -0.0331578 |
| MED13 | mediator complex subunit 13 | -0.0330426 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0329542 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0327082 |
| PHF21A | PHD finger protein 21A | -0.0323717 |
| SMYD3 | SET and MYND domain containing 3 | -0.0323044 |
| BPTF | bromodomain PHD finger transcription factor | -0.0322013 |
| B2M | beta-2-microglobulin | -0.0320682 |
| MEIS2 | Meis homeobox 2 | -0.0319241 |
| RPL9 | ribosomal protein L9 | -0.0317824 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | -0.0316005 |
| EGFR | epidermal growth factor receptor | -0.0315747 |
| TRIB2 | tribbles pseudokinase 2 | -0.0313063 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.0311553 |
| CUX1 | cut-like homeobox 1 | -0.031129 |
| TMSB10 | thymosin beta 10 | -0.031063 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0308186 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0306921 |
| GOLGA4 | golgin A4 | -0.0305217 |
| SLC39A11 | solute carrier family 39, member 11 | -0.0304976 |
| CCDC88A | coiled-coil domain containing 88A | -0.0302893 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0302446 |
| LOX | lysyl oxidase | -0.0298195 |
| RTN4 | reticulon 4 | -0.0298179 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 | -0.0291083 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0289628 |
| ZNF609 | zinc finger protein 609 | -0.0287872 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.028749 |
| JPT1 | Jupiter microtubule associated homolog 1 | -0.0286395 |
| CCNY | cyclin Y | -0.0286172 |
| SETD5 | SET domain containing 5 | -0.0285729 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0284518 |
| HIP1 | huntingtin interacting protein 1 | -0.0284305 |
| PLAT | plasminogen activator, tissue | -0.0283873 |
