| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ixazomib citrate perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ixazomib citrate_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.175189 |
| B2M | beta-2-microglobulin | 0.14017 |
| UBC | ubiquitin C | 0.0725515 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0647666 |
| ASPH | aspartate beta-hydroxylase | 0.060878 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0502272 |
| AREG | amphiregulin | 0.0501106 |
| PTMA | prothymosin, alpha | 0.0430199 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0421283 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.040152 |
| APOL1 | apolipoprotein L, 1 | 0.0372484 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0366846 |
| DST | dystonin | 0.0362996 |
| C6ORF132 | chromosome 6 open reading frame 132 | 0.0348777 |
| LIMA1 | LIM domain and actin binding 1 | 0.0345819 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0325785 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0323447 |
| PCDHB16 | protocadherin beta 16 | 0.0315452 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0309905 |
| LCN2 | lipocalin 2 | 0.03078 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0307044 |
| FAM219A | family with sequence similarity 219, member A | 0.0295978 |
| MT2A | metallothionein 2A | 0.0285665 |
| KRT19 | keratin 19, type I | 0.0275837 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0274695 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0273112 |
| FTL | ferritin, light polypeptide | 0.0270647 |
| PSMD1 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 | 0.0267874 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0267531 |
| RPS3 | ribosomal protein S3 | 0.0259394 |
| MYH14 | myosin, heavy chain 14, non-muscle | 0.025005 |
| SFTPA2 | surfactant protein A2 | 0.0246696 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | 0.0244153 |
| KIF1B | kinesin family member 1B | 0.0238501 |
| ECPAS | Ecm29 proteasome adaptor and scaffold | 0.0233822 |
| NPLOC4 | nuclear protein localization 4 homolog (S. cerevisiae) | 0.0233566 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0232572 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0231316 |
| CST3 | cystatin C | 0.022882 |
| TXNRD1 | thioredoxin reductase 1 | 0.0224828 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 | 0.0222816 |
| RPL7L1 | ribosomal protein L7-like 1 | 0.0221052 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0219796 |
| TMC5 | transmembrane channel-like 5 | 0.0213991 |
| TMSB10 | thymosin beta 10 | 0.0213282 |
| NT5C3A | 5'-nucleotidase, cytosolic IIIA | 0.0209179 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0208048 |
| SLC38A1 | solute carrier family 38, member 1 | 0.0207218 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | 0.0206358 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0201035 |
| JUN | jun proto-oncogene | 0.0199281 |
| ZFP36 | ZFP36 ring finger protein | 0.0197146 |
| MDK | midkine (neurite growth-promoting factor 2) | 0.0195444 |
| IFITM3 | interferon induced transmembrane protein 3 | 0.0193616 |
| HSPA1B | heat shock 70kDa protein 1B | 0.0190515 |
| KIF21A | kinesin family member 21A | 0.019046 |
| S100A6 | S100 calcium binding protein A6 | 0.0189268 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0187568 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0186286 |
| S100P | S100 calcium binding protein P | 0.0183122 |
| DLGAP3 | discs, large (Drosophila) homolog-associated protein 3 | 0.0182561 |
| CD44 | CD44 molecule (Indian blood group) | 0.0181379 |
| UBXN4 | UBX domain protein 4 | 0.0180477 |
| SNX29 | sorting nexin 29 | 0.0177925 |
| IFNGR1 | interferon gamma receptor 1 | 0.0177264 |
| TFF3 | trefoil factor 3 (intestinal) | 0.0176822 |
| ENO1 | enolase 1, (alpha) | 0.0176412 |
| TMPRSS4 | transmembrane protease, serine 4 | 0.0176288 |
| HLA-A | major histocompatibility complex, class I, A | 0.0175861 |
| TAPBP | TAP binding protein (tapasin) | 0.0174989 |
| S100A9 | S100 calcium binding protein A9 | 0.0174525 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.016845 |
| UBR3 | ubiquitin protein ligase E3 component n-recognin 3 (putative) | 0.0167899 |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 | 0.0167207 |
| BMP4 | bone morphogenetic protein 4 | 0.0166596 |
| POMP | proteasome maturation protein | 0.0165751 |
| TPI1 | triosephosphate isomerase 1 | 0.0165316 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.0164534 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | 0.0162635 |
| PSMD11 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 | 0.0162292 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0159498 |
| EFHD2 | EF-hand domain family, member D2 | 0.0159284 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0158862 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0158176 |
| KRT18 | keratin 18, type I | 0.0157788 |
| POTEF | POTE ankyrin domain family, member F | 0.0157102 |
| MT1X | metallothionein 1X | 0.0156982 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.0156398 |
| RPL35A | ribosomal protein L35a | 0.0155865 |
| CTSD | cathepsin D | 0.0154298 |
| ABCC2 | ATP-binding cassette, sub-family C (CFTR/MRP), member 2 | 0.0152756 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0152416 |
| SERF2 | small EDRK-rich factor 2 | 0.0149032 |
| KPNA3 | karyopherin alpha 3 (importin alpha 4) | 0.0148978 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.014887 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0148585 |
| S100A11 | S100 calcium binding protein A11 | 0.0147624 |
| RPS6 | ribosomal protein S6 | 0.0147358 |
| RPL23 | ribosomal protein L23 | 0.0147276 |
| LY6E | lymphocyte antigen 6 complex, locus E | 0.0146378 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | -0.1293 |
| INTS6 | integrator complex subunit 6 | -0.126444 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.123145 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.102073 |
| PHF3 | PHD finger protein 3 | -0.0983807 |
| VCL | vinculin | -0.0971961 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.096719 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0901562 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | -0.0852259 |
| RUNX1 | runt-related transcription factor 1 | -0.0815167 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0808361 |
| ANXA2 | annexin A2 | -0.0803445 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0751877 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0747463 |
| SQSTM1 | sequestosome 1 | -0.0703747 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0679727 |
| RAD51B | RAD51 paralog B | -0.0647947 |
| PLSCR2 | phospholipid scramblase 2 | -0.0634366 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0633662 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0632696 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0630892 |
| AHI1 | Abelson helper integration site 1 | -0.0594693 |
| LMO7 | LIM domain 7 | -0.0576693 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0569901 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0568538 |
| PRKCA | protein kinase C, alpha | -0.0556197 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0555818 |
| RNF213 | ring finger protein 213 | -0.0534042 |
| EPHB2 | EPH receptor B2 | -0.0528084 |
| PLSCR1 | phospholipid scramblase 1 | -0.0524222 |
| NCKAP5 | NCK-associated protein 5 | -0.047719 |
| IRF1 | interferon regulatory factor 1 | -0.0468144 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0467902 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0467407 |
| SERINC5 | serine incorporator 5 | -0.0465112 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.0456682 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | -0.0447228 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0446486 |
| RNF43 | ring finger protein 43 | -0.0445717 |
| MX1 | MX dynamin-like GTPase 1 | -0.0442801 |
| CANX | calnexin | -0.0441029 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.0438963 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0436514 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | -0.0436335 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.043551 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.04331 |
| ATXN1 | ataxin 1 | -0.0428016 |
| FNDC3B | fibronectin type III domain containing 3B | -0.042779 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.0426935 |
| RBM39 | RNA binding motif protein 39 | -0.0421718 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0420271 |
| HM13 | histocompatibility (minor) 13 | -0.0413422 |
| EZR | ezrin | -0.0409806 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0409643 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0408212 |
| ZNF292 | zinc finger protein 292 | -0.039809 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0394433 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | -0.0387527 |
| HDAC4 | histone deacetylase 4 | -0.0386464 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0377612 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0366952 |
| TUFT1 | tuftelin 1 | -0.0365712 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0365151 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | -0.0362252 |
| ATP11A | ATPase, class VI, type 11A | -0.036185 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0360179 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0349999 |
| TNRC6B | trinucleotide repeat containing 6B | -0.0348438 |
| PRELID2 | PRELI domain containing 2 | -0.0345767 |
| MSI2 | musashi RNA-binding protein 2 | -0.034231 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.0341431 |
| MORF4L2 | mortality factor 4 like 2 | -0.0332859 |
| RIGI | RNA sensor RIG-I | -0.0330629 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.032816 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0326934 |
| SMAD3 | SMAD family member 3 | -0.0326839 |
| TSC22D1 | TSC22 domain family, member 1 | -0.0324719 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | -0.0322109 |
| ARF1 | ADP-ribosylation factor 1 | -0.0319367 |
| IRS2 | insulin receptor substrate 2 | -0.0316357 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.031523 |
| PPARGC1A | peroxisome proliferator-activated receptor gamma, coactivator 1 alpha | -0.0314099 |
| RRBP1 | ribosome binding protein 1 | -0.0313994 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0311447 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.031054 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | -0.0310441 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | -0.0305412 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0303523 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | -0.0301079 |
| TNS4 | tensin 4 | -0.0298188 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0296644 |
| PKM | pyruvate kinase, muscle | -0.0294764 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 | -0.0286053 |
| WWOX | WW domain containing oxidoreductase | -0.0284225 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0283771 |
| TC2N | tandem C2 domains, nuclear | -0.0283241 |
| SEC24D | SEC24 family member D | -0.0282795 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0282414 |
| TM9SF2 | transmembrane 9 superfamily member 2 | -0.0276558 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0273373 |
