| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ixazomib citrate perturbation in H4 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ixazomib citrate_H4 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.10256 |
| INHBA | inhibin, beta A | 0.0876219 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0767442 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0522624 |
| FAM13A | family with sequence similarity 13, member A | 0.0484236 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0398788 |
| STC1 | stanniocalcin 1 | 0.0369114 |
| ZNF395 | zinc finger protein 395 | 0.0336002 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | 0.0319289 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0310698 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0303836 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0296238 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0283303 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.0278284 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0277767 |
| TPM3 | tropomyosin 3 | 0.0266602 |
| GOLGA4 | golgin A4 | 0.0253599 |
| ZNF841 | zinc finger protein 841 | 0.0242415 |
| CTSB | cathepsin B | 0.0234394 |
| MSN | moesin | 0.0232568 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0225359 |
| BOD1L1 | biorientation of chromosomes in cell division 1-like 1 | 0.0222693 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0220456 |
| ZNF160 | zinc finger protein 160 | 0.021889 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.021592 |
| SRP54 | signal recognition particle 54kDa | 0.0215031 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0213127 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0213037 |
| CAVIN1 | caveolae associated protein 1 | 0.0211327 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0208626 |
| MKI67 | marker of proliferation Ki-67 | 0.020776 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.019889 |
| PMM2 | phosphomannomutase 2 | 0.0195734 |
| HELZ | helicase with zinc finger | 0.0195544 |
| TMEM263 | transmembrane protein 263 | 0.0193221 |
| SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) | 0.0188601 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0187463 |
| GOLGB1 | golgin B1 | 0.018348 |
| GPR107 | G protein-coupled receptor 107 | 0.0183414 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0178118 |
| NGLY1 | N-glycanase 1 | 0.0175628 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.0174084 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | 0.0173619 |
| CENPF | centromere protein F, 350/400kDa | 0.017357 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.017271 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0171612 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0166239 |
| HDGF | hepatoma-derived growth factor | 0.0164926 |
| TPR | translocated promoter region, nuclear basket protein | 0.0163638 |
| SERF2 | small EDRK-rich factor 2 | 0.0162698 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0161734 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0158555 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0158219 |
| WDR36 | WD repeat domain 36 | 0.0155618 |
| NDRG1 | N-myc downstream regulated 1 | 0.0152706 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0151762 |
| SFXN1 | sideroflexin 1 | 0.0148202 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0147998 |
| FAM219A | family with sequence similarity 219, member A | 0.0147427 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0147255 |
| CCDC47 | coiled-coil domain containing 47 | 0.0146983 |
| PGRMC2 | progesterone receptor membrane component 2 | 0.0145626 |
| CALCOCO2 | calcium binding and coiled-coil domain 2 | 0.0145325 |
| TMF1 | TATA element modulatory factor 1 | 0.0142413 |
| SUCO | SUN domain containing ossification factor | 0.014121 |
| MYOF | myoferlin | 0.0140682 |
| TIAL1 | TIA1 cytotoxic granule-associated RNA binding protein-like 1 | 0.0139704 |
| ELP2 | elongator acetyltransferase complex subunit 2 | 0.013955 |
| HDLBP | high density lipoprotein binding protein | 0.0139009 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | 0.0138857 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | 0.0138055 |
| GOLGA2 | golgin A2 | 0.0138048 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.013794 |
| PGK1 | phosphoglycerate kinase 1 | 0.0137864 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0137648 |
| MKRN1 | makorin ring finger protein 1 | 0.0137272 |
| EFCAB14 | EF-hand calcium binding domain 14 | 0.0134817 |
| NAV2 | neuron navigator 2 | 0.0134268 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0133553 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0133127 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0132712 |
| TAPBP | TAP binding protein (tapasin) | 0.0132599 |
| NBEAL1 | neurobeachin-like 1 | 0.0132435 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0130844 |
| ARRDC3 | arrestin domain containing 3 | 0.0130227 |
| SDC4 | syndecan 4 | 0.0130173 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | 0.0129493 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.0129387 |
| RAB8B | RAB8B, member RAS oncogene family | 0.012905 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0128414 |
| RIOK3 | RIO kinase 3 | 0.0127313 |
| SPTY2D1 | SPT2, Suppressor of Ty, domain containing 1 (S. cerevisiae) | 0.012724 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0125851 |
| ESCO1 | establishment of sister chromatid cohesion N-acetyltransferase 1 | 0.0125298 |
| SRP9 | signal recognition particle 9kDa | 0.0124728 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0123512 |
| SFTPA2 | surfactant protein A2 | 0.0123473 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0123402 |
| CYLD | cylindromatosis (turban tumor syndrome) | 0.0122783 |
| CLTC | clathrin, heavy chain (Hc) | 0.0122524 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NALF1 | NALCN channel auxiliary factor 1 | -0.243147 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.222021 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.218097 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.098379 |
| FTL | ferritin, light polypeptide | -0.0955252 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0950612 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0878745 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0810318 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0759895 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0734632 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0706768 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0697213 |
| ASPH | aspartate beta-hydroxylase | -0.0674236 |
| CD44 | CD44 molecule (Indian blood group) | -0.062575 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.061435 |
| FN1 | fibronectin 1 | -0.0610235 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0604733 |
| GLIS3 | GLIS family zinc finger 3 | -0.0593419 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0586255 |
| VCL | vinculin | -0.0575778 |
| KYNU | kynureninase | -0.0569979 |
| PKM | pyruvate kinase, muscle | -0.0565296 |
| RTN4 | reticulon 4 | -0.0536832 |
| HDAC9 | histone deacetylase 9 | -0.0535323 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0522358 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0511878 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0487993 |
| OSMR | oncostatin M receptor | -0.0477036 |
| TENM3 | teneurin transmembrane protein 3 | -0.0469999 |
| NLGN1 | neuroligin 1 | -0.04688 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0468719 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0467665 |
| PHF14 | PHD finger protein 14 | -0.0439142 |
| ACTN4 | actinin, alpha 4 | -0.043756 |
| NAV1 | neuron navigator 1 | -0.0436425 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | -0.0426536 |
| ATXN1 | ataxin 1 | -0.0421684 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0417539 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0394072 |
| EGR1 | early growth response 1 | -0.0393968 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0386693 |
| USP34 | ubiquitin specific peptidase 34 | -0.0374765 |
| AUTS2 | autism susceptibility candidate 2 | -0.0363458 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0358557 |
| FBXO11 | F-box protein 11 | -0.0357784 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0357564 |
| RPLP1 | ribosomal protein, large, P1 | -0.0357218 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0356042 |
| BPTF | bromodomain PHD finger transcription factor | -0.0354142 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0352092 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0350813 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.0349997 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0348714 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | -0.0345937 |
| RUNX1 | runt-related transcription factor 1 | -0.0345574 |
| BBS9 | Bardet-Biedl syndrome 9 | -0.0345251 |
| LYPD6B | LY6/PLAUR domain containing 6B | -0.0333399 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0332929 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.032485 |
| STK17A | serine/threonine kinase 17a | -0.0321812 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0312586 |
| DTNA | dystrobrevin, alpha | -0.0310502 |
| ACTN1 | actinin, alpha 1 | -0.0310365 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0304947 |
| RPL28 | ribosomal protein L28 | -0.0304454 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0302414 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | -0.0301914 |
| SMYD3 | SET and MYND domain containing 3 | -0.0300791 |
| SPAG9 | sperm associated antigen 9 | -0.0295829 |
| DST | dystonin | -0.0294605 |
| SYT1 | synaptotagmin I | -0.0293315 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.029297 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0292092 |
| PTK2 | protein tyrosine kinase 2 | -0.0289507 |
| ARHGAP24 | Rho GTPase activating protein 24 | -0.028941 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0288348 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.028759 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0284351 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0283317 |
| AHR | aryl hydrocarbon receptor | -0.0281819 |
| SBF2 | SET binding factor 2 | -0.027941 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0277473 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0276141 |
| CDK14 | cyclin-dependent kinase 14 | -0.0275923 |
| DGKI | diacylglycerol kinase, iota | -0.027512 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0272566 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | -0.0271425 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0267128 |
| ZFYVE28 | zinc finger, FYVE domain containing 28 | -0.0266779 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.026414 |
| PRELID2 | PRELI domain containing 2 | -0.0264106 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0264038 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0261797 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.026052 |
| HLA-B | major histocompatibility complex, class I, B | -0.0259099 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0257462 |
| NF1 | neurofibromin 1 | -0.0256986 |
| TNS3 | tensin 3 | -0.0255106 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.025259 |
| MYO10 | myosin X | -0.0250971 |
