| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ixazomib citrate perturbation in HOP62 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ixazomib citrate_HOP62 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0719538 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0641443 |
| CD44 | CD44 molecule (Indian blood group) | 0.0633173 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0629072 |
| MT2A | metallothionein 2A | 0.0556377 |
| ASPH | aspartate beta-hydroxylase | 0.0443522 |
| AHNAK | AHNAK nucleoprotein | 0.0422478 |
| VCL | vinculin | 0.0420418 |
| RFX8 | RFX family member 8, lacking RFX DNA binding domain | 0.0400033 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0350961 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0348865 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0329594 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0311483 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0307948 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0262363 |
| CAPRIN2 | caprin family member 2 | 0.024613 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0242459 |
| SEPTIN9 | septin 9 | 0.0238149 |
| MAP1B | microtubule-associated protein 1B | 0.0205034 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0200327 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0194347 |
| MKI67 | marker of proliferation Ki-67 | 0.019267 |
| NECTIN2 | nectin cell adhesion molecule 2 | 0.0192551 |
| RCOR1 | REST corepressor 1 | 0.0182481 |
| DUSP6 | dual specificity phosphatase 6 | 0.0179167 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0179053 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0178856 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0175582 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0173753 |
| CENPF | centromere protein F, 350/400kDa | 0.0172949 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0168413 |
| RRM2 | ribonucleotide reductase M2 | 0.0163755 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0162108 |
| RPL4 | ribosomal protein L4 | 0.0159715 |
| RPS3 | ribosomal protein S3 | 0.0159055 |
| DNMBP | dynamin binding protein | 0.0157666 |
| RPL14 | ribosomal protein L14 | 0.0155284 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0149996 |
| ACTN1 | actinin, alpha 1 | 0.0146059 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0141296 |
| WWOX | WW domain containing oxidoreductase | 0.0139405 |
| CD59 | CD59 molecule, complement regulatory protein | 0.0138928 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0138118 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0135612 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0135323 |
| PLEC | plectin | 0.0134881 |
| TAPBP | TAP binding protein (tapasin) | 0.0132842 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0132672 |
| ENO1 | enolase 1, (alpha) | 0.0132431 |
| TOP1 | topoisomerase (DNA) I | 0.0130779 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0130638 |
| H1-4 | H1.4 linker histone, cluster member | 0.0130597 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0130193 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0130043 |
| FHIT | fragile histidine triad | 0.0125445 |
| APP | amyloid beta (A4) precursor protein | 0.0124475 |
| CORO1C | coronin, actin binding protein, 1C | 0.012331 |
| MLPH | melanophilin | 0.0122345 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.0119962 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0119945 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0119713 |
| PDE4DIP | phosphodiesterase 4D interacting protein | 0.0119417 |
| LDHA | lactate dehydrogenase A | 0.0118629 |
| VASP | vasodilator-stimulated phosphoprotein | 0.0118553 |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) | 0.0117477 |
| BCAP31 | B-cell receptor-associated protein 31 | 0.011723 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0117169 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0116726 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0114999 |
| SET | SET nuclear proto-oncogene | 0.0113954 |
| G0S2 | G0/G1 switch 2 | 0.0113756 |
| HMGB2 | high mobility group box 2 | 0.011213 |
| YBX3 | Y box binding protein 3 | 0.011168 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0111555 |
| EZR | ezrin | 0.0110083 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0109979 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0109737 |
| KIAA1217 | KIAA1217 | 0.0109065 |
| NAV2 | neuron navigator 2 | 0.010817 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.010799 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0107824 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.010781 |
| SERINC1 | serine incorporator 1 | 0.0107777 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | 0.0107703 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0105414 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0104141 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0103828 |
| JAG1 | jagged 1 | 0.0103544 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0102671 |
| RASA2 | RAS p21 protein activator 2 | 0.0101864 |
| CLIC4 | chloride intracellular channel 4 | 0.0101598 |
| ANGPTL4 | angiopoietin-like 4 | 0.0101215 |
| GLRX | glutaredoxin (thioltransferase) | 0.0101132 |
| RBBP7 | retinoblastoma binding protein 7 | 0.0100117 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.00994112 |
| GRAMD1B | GRAM domain containing 1B | 0.00985406 |
| STX1A | syntaxin 1A (brain) | 0.00978339 |
| SMAD3 | SMAD family member 3 | 0.009484 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.00946377 |
| CAVIN1 | caveolae associated protein 1 | 0.00918752 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.354756 |
| VIM | vimentin | -0.31586 |
| IGF2 | insulin-like growth factor 2 | -0.188605 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.172983 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.138728 |
| CDH13 | cadherin 13 | -0.132178 |
| NDRG1 | N-myc downstream regulated 1 | -0.119799 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.119193 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.103813 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.103224 |
| COL6A1 | collagen, type VI, alpha 1 | -0.102731 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0918767 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0869629 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0803765 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0797208 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0720578 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0681257 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0665717 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0628582 |
| TMSB10 | thymosin beta 10 | -0.0621809 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0610602 |
| PDE10A | phosphodiesterase 10A | -0.0601904 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0591181 |
| HMGA2 | high mobility group AT-hook 2 | -0.0588588 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0568361 |
| FTL | ferritin, light polypeptide | -0.0552466 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0537154 |
| LOX | lysyl oxidase | -0.0530317 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0521783 |
| CD109 | CD109 molecule | -0.0514093 |
| FAM13A | family with sequence similarity 13, member A | -0.0507618 |
| MYO10 | myosin X | -0.0495666 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0485608 |
| SETD5 | SET domain containing 5 | -0.048513 |
| USP34 | ubiquitin specific peptidase 34 | -0.0477532 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0475123 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0472374 |
| TMEM165 | transmembrane protein 165 | -0.0463126 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0451424 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0433023 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0430605 |
| STC1 | stanniocalcin 1 | -0.0423679 |
| RUNX1 | runt-related transcription factor 1 | -0.0407161 |
| SBF2 | SET binding factor 2 | -0.0402513 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0394055 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.039247 |
| COL5A1 | collagen, type V, alpha 1 | -0.0389987 |
| COL6A2 | collagen, type VI, alpha 2 | -0.038456 |
| COPA | coatomer protein complex, subunit alpha | -0.0378505 |
| SEC24A | SEC24 family member A | -0.0359516 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0358207 |
| UBC | ubiquitin C | -0.0350859 |
| NF1 | neurofibromin 1 | -0.0347088 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0346442 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0341544 |
| RNF24 | ring finger protein 24 | -0.0340347 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0328785 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0323466 |
| ADM | adrenomedullin | -0.0321695 |
| MMP12 | matrix metallopeptidase 12 | -0.0321112 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0319801 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0319585 |
| VEGFA | vascular endothelial growth factor A | -0.0316354 |
| CLMP | CXADR-like membrane protein | -0.0305067 |
| NGLY1 | N-glycanase 1 | -0.0300346 |
| RAI14 | retinoic acid induced 14 | -0.030019 |
| CCND1 | cyclin D1 | -0.0296426 |
| PTK2 | protein tyrosine kinase 2 | -0.0296 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0295525 |
| FMN1 | formin 1 | -0.0294684 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0294236 |
| EXT1 | exostosin glycosyltransferase 1 | -0.029085 |
| ZNF207 | zinc finger protein 207 | -0.0290713 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | -0.0288705 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.028829 |
| MORF4L2 | mortality factor 4 like 2 | -0.0286186 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0285731 |
| PKM | pyruvate kinase, muscle | -0.028306 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0282108 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0279793 |
| WASF2 | WAS protein family, member 2 | -0.0277852 |
| CADM1 | cell adhesion molecule 1 | -0.0277072 |
| SEC24D | SEC24 family member D | -0.0276868 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0276104 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0275265 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.0273892 |
| HSPA8 | heat shock 70kDa protein 8 | -0.027128 |
| GOLGA4 | golgin A4 | -0.0270478 |
| TENM2 | teneurin transmembrane protein 2 | -0.026939 |
| CUX1 | cut-like homeobox 1 | -0.0267535 |
| HM13 | histocompatibility (minor) 13 | -0.0267449 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0264237 |
| CANX | calnexin | -0.026265 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0260116 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0259539 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0257503 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0257029 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0254431 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 | -0.025357 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0253479 |
