| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ixazomib citrate perturbation in HT-29 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ixazomib citrate_HT-29 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0671398 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0476049 |
| TXNRD1 | thioredoxin reductase 1 | 0.0451818 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0287565 |
| RPS3 | ribosomal protein S3 | 0.0200379 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0186799 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0183235 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0172212 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0168768 |
| PCDHB16 | protocadherin beta 16 | 0.0162223 |
| RPL9 | ribosomal protein L9 | 0.0150306 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0147879 |
| HYOU1 | hypoxia up-regulated 1 | 0.0147742 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0146936 |
| PSMD1 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 | 0.0145089 |
| RPLP0 | ribosomal protein, large, P0 | 0.0144221 |
| PSMD12 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 | 0.0139485 |
| RPL35A | ribosomal protein L35a | 0.0137461 |
| TNPO1 | transportin 1 | 0.0137085 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0136591 |
| RPL12 | ribosomal protein L12 | 0.0132224 |
| RPL11 | ribosomal protein L11 | 0.0131995 |
| GCLM | glutamate-cysteine ligase, modifier subunit | 0.0129544 |
| GOLGA4 | golgin A4 | 0.0128276 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0122981 |
| ECPAS | Ecm29 proteasome adaptor and scaffold | 0.0118964 |
| AREG | amphiregulin | 0.0118601 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | 0.0116274 |
| MYL12B | myosin, light chain 12B, regulatory | 0.0112768 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0111143 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | 0.0110999 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.0110522 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | 0.0106036 |
| BAG3 | BCL2-associated athanogene 3 | 0.0103524 |
| UBQLN1 | ubiquilin 1 | 0.0102268 |
| DNAJC2 | DnaJ (Hsp40) homolog, subfamily C, member 2 | 0.0102035 |
| B2M | beta-2-microglobulin | 0.0101886 |
| BRD2 | bromodomain containing 2 | 0.00998316 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.00993397 |
| PGM3 | phosphoglucomutase 3 | 0.00963392 |
| TMF1 | TATA element modulatory factor 1 | 0.0094863 |
| ATP5F1E | ATP synthase F1 subunit epsilon | 0.00936715 |
| FAM219A | family with sequence similarity 219, member A | 0.00935164 |
| CCDC186 | coiled-coil domain containing 186 | 0.00929496 |
| PSMD11 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 | 0.0091446 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.00914176 |
| UFD1 | ubiquitin recognition factor in ER associated degradation 1 | 0.00906704 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.00899064 |
| RBM25 | RNA binding motif protein 25 | 0.00897893 |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 | 0.00890508 |
| USP47 | ubiquitin specific peptidase 47 | 0.00888485 |
| DNAJC25 | DnaJ (Hsp40) homolog, subfamily C , member 25 | 0.00871661 |
| NFXL1 | nuclear transcription factor, X-box binding-like 1 | 0.00859077 |
| POMP | proteasome maturation protein | 0.00853392 |
| COPB1 | coatomer protein complex, subunit beta 1 | 0.00836254 |
| VIM | vimentin | 0.00818699 |
| OGA | O-GlcNAcase | 0.00810667 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.00809221 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.00793733 |
| RPL7 | ribosomal protein L7 | 0.00787105 |
| RPS24 | ribosomal protein S24 | 0.00787071 |
| TMED2 | transmembrane emp24 domain trafficking protein 2 | 0.00786454 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | 0.00785801 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | 0.00784482 |
| NTN4 | netrin 4 | 0.00783651 |
| SUCO | SUN domain containing ossification factor | 0.00778076 |
| MT2A | metallothionein 2A | 0.00778012 |
| PHLDA2 | pleckstrin homology-like domain, family A, member 2 | 0.00775679 |
| CLPTM1L | CLPTM1-like | 0.00770635 |
| ZFAND5 | zinc finger, AN1-type domain 5 | 0.00769518 |
| DNTTIP2 | deoxynucleotidyltransferase, terminal, interacting protein 2 | 0.00764654 |
| KIF1B | kinesin family member 1B | 0.00764565 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.00759427 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | 0.00755674 |
| EREG | epiregulin | 0.00754539 |
| SLMAP | sarcolemma associated protein | 0.00749272 |
| PSMA4 | proteasome (prosome, macropain) subunit, alpha type, 4 | 0.00738768 |
| TXNL1 | thioredoxin-like 1 | 0.0073672 |
| EIF5B | eukaryotic translation initiation factor 5B | 0.00726222 |
| CREBRF | CREB3 regulatory factor | 0.00721766 |
| SKP1 | S-phase kinase-associated protein 1 | 0.00717362 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 | 0.00715732 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.00714694 |
| GOLT1B | golgi transport 1B | 0.00692355 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.00687865 |
| CRY1 | cryptochrome circadian clock 1 | 0.00683844 |
| DHX29 | DEAH (Asp-Glu-Ala-His) box polypeptide 29 | 0.00679186 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.00677603 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | 0.00677229 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.00664135 |
| DNAJB11 | DnaJ (Hsp40) homolog, subfamily B, member 11 | 0.00658981 |
| STK17A | serine/threonine kinase 17a | 0.00652687 |
| NCKAP1 | NCK-associated protein 1 | 0.00651577 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.00649567 |
| HSPA1A | heat shock 70kDa protein 1A | 0.00649377 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.00647595 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.00644948 |
| BRD4 | bromodomain containing 4 | 0.00643111 |
| SRP72 | signal recognition particle 72kDa | 0.0063655 |
| TBC1D23 | TBC1 domain family, member 23 | 0.00634758 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.191531 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.143202 |
| MYH14 | myosin, heavy chain 14, non-muscle | -0.131581 |
| NDRG1 | N-myc downstream regulated 1 | -0.130231 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.12391 |
| ACTN4 | actinin, alpha 4 | -0.123784 |
| AHNAK | AHNAK nucleoprotein | -0.113655 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.108781 |
| ANXA2 | annexin A2 | -0.104154 |
| SLC45A4 | solute carrier family 45, member 4 | -0.103314 |
| EZR | ezrin | -0.102422 |
| LYZ | lysozyme | -0.101222 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | -0.0998526 |
| FRY | furry homolog (Drosophila) | -0.0940688 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0924443 |
| PTK2 | protein tyrosine kinase 2 | -0.0856162 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0842503 |
| FTL | ferritin, light polypeptide | -0.081636 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.080153 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0797999 |
| ITPKC | inositol-trisphosphate 3-kinase C | -0.0769392 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0755888 |
| NECTIN2 | nectin cell adhesion molecule 2 | -0.0741937 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0728421 |
| DGKH | diacylglycerol kinase, eta | -0.0722193 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0705576 |
| STK24 | serine/threonine kinase 24 | -0.0687655 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0687379 |
| ETV6 | ets variant 6 | -0.068452 |
| KRT20 | keratin 20, type I | -0.0679456 |
| LMO7 | LIM domain 7 | -0.0672317 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0671495 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | -0.0640365 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0638641 |
| TRAPPC9 | trafficking protein particle complex 9 | -0.0630808 |
| PRELID2 | PRELI domain containing 2 | -0.0628264 |
| DIAPH2 | diaphanous-related formin 2 | -0.0627554 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0625568 |
| MYO1E | myosin IE | -0.0621693 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0616429 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | -0.058918 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0577588 |
| WASF2 | WAS protein family, member 2 | -0.0573704 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.0567808 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | -0.0563123 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.056194 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0560227 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0558774 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0556747 |
| KRT8 | keratin 8, type II | -0.0551879 |
| TJP1 | tight junction protein 1 | -0.0546592 |
| KLF3 | Kruppel-like factor 3 (basic) | -0.0542464 |
| NSMCE2 | non-SMC element 2, MMS21 homolog (S. cerevisiae) | -0.0540146 |
| CTBP2 | C-terminal binding protein 2 | -0.0536196 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.052665 |
| FAT1 | FAT atypical cadherin 1 | -0.0524528 |
| WWC1 | WW and C2 domain containing 1 | -0.0524261 |
| NF1 | neurofibromin 1 | -0.0521459 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0520118 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0518171 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0507695 |
| PCED1B | PC-esterase domain containing 1B | -0.0495135 |
| ANXA11 | annexin A11 | -0.048909 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0488256 |
| ACACA | acetyl-CoA carboxylase alpha | -0.0485533 |
| TMEM123 | transmembrane protein 123 | -0.0483297 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | -0.0479716 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0478962 |
| EXOC4 | exocyst complex component 4 | -0.0476771 |
| BPTF | bromodomain PHD finger transcription factor | -0.047605 |
| DNM2 | dynamin 2 | -0.0474305 |
| ATXN1 | ataxin 1 | -0.0473104 |
| RHPN2 | rhophilin, Rho GTPase binding protein 2 | -0.0469598 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0469521 |
| MECOM | MDS1 and EVI1 complex locus | -0.0467551 |
| NIBAN2 | niban apoptosis regulator 2 | -0.0467428 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.0464074 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0460161 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | -0.0451556 |
| SMAD3 | SMAD family member 3 | -0.0450006 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0445301 |
| PKM | pyruvate kinase, muscle | -0.0445083 |
| RNF213 | ring finger protein 213 | -0.0442482 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0437163 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | -0.0436711 |
| TMC5 | transmembrane channel-like 5 | -0.0435032 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0432444 |
| POF1B | premature ovarian failure, 1B | -0.043159 |
| JUP | junction plakoglobin | -0.0431287 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0427683 |
| UTRN | utrophin | -0.0422906 |
| CAMK2D | calcium/calmodulin-dependent protein kinase II delta | -0.0418382 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0417682 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0415868 |
| PKP4 | plakophilin 4 | -0.0415325 |
| TCF12 | transcription factor 12 | -0.0415147 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.041407 |
| BCAS1 | breast carcinoma amplified sequence 1 | -0.0410538 |
| MLLT3 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 | -0.0400928 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0398697 |
