| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ixazomib citrate perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ixazomib citrate_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.158467 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.122957 |
| KRT17 | keratin 17, type I | 0.102206 |
| UBC | ubiquitin C | 0.0730411 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0636657 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0624676 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0549428 |
| PTMA | prothymosin, alpha | 0.0512639 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0504403 |
| SQLE | squalene epoxidase | 0.0498712 |
| FTL | ferritin, light polypeptide | 0.0484255 |
| RPS6 | ribosomal protein S6 | 0.0479512 |
| SQSTM1 | sequestosome 1 | 0.04396 |
| RPS3 | ribosomal protein S3 | 0.0407 |
| MSN | moesin | 0.0381328 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0376485 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0375567 |
| KRT14 | keratin 14, type I | 0.0366889 |
| ANXA1 | annexin A1 | 0.0359852 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | 0.0350651 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0342313 |
| HSPA1A | heat shock 70kDa protein 1A | 0.030886 |
| YBX1 | Y box binding protein 1 | 0.0292944 |
| KRT6A | keratin 6A, type II | 0.0287765 |
| CLU | clusterin | 0.0287531 |
| B2M | beta-2-microglobulin | 0.0282149 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0270326 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0254838 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0253986 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0251013 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0249983 |
| RPL12 | ribosomal protein L12 | 0.0238999 |
| RPS8 | ribosomal protein S8 | 0.0223087 |
| SPAG9 | sperm associated antigen 9 | 0.022185 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | 0.02148 |
| TPM3 | tropomyosin 3 | 0.0211962 |
| MT2A | metallothionein 2A | 0.0210792 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.020803 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0206661 |
| ARRDC3 | arrestin domain containing 3 | 0.0204628 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0198625 |
| SFTPA2 | surfactant protein A2 | 0.019729 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0196144 |
| POTEF | POTE ankyrin domain family, member F | 0.0194728 |
| ECPAS | Ecm29 proteasome adaptor and scaffold | 0.0189205 |
| HDGF | hepatoma-derived growth factor | 0.018899 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.018825 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0186482 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0182723 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.018252 |
| RPL11 | ribosomal protein L11 | 0.017718 |
| SLK | STE20-like kinase | 0.0174406 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0173554 |
| TAPBP | TAP binding protein (tapasin) | 0.0168786 |
| RPS12 | ribosomal protein S12 | 0.0167752 |
| RPS2 | ribosomal protein S2 | 0.0166764 |
| RPS13 | ribosomal protein S13 | 0.0166555 |
| BRD2 | bromodomain containing 2 | 0.0165696 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0162864 |
| UBQLN1 | ubiquilin 1 | 0.0161883 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0161609 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0160783 |
| ZFP36 | ZFP36 ring finger protein | 0.0159769 |
| SET | SET nuclear proto-oncogene | 0.0158881 |
| NUP58 | nucleoporin 58 | 0.0154129 |
| DLGAP3 | discs, large (Drosophila) homolog-associated protein 3 | 0.0153958 |
| RPS19 | ribosomal protein S19 | 0.0153149 |
| GOLGA4 | golgin A4 | 0.0152625 |
| PCBP2 | poly(rC) binding protein 2 | 0.0152064 |
| DSTN | destrin (actin depolymerizing factor) | 0.0152063 |
| RPL3 | ribosomal protein L3 | 0.0148671 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.0144441 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | 0.0143739 |
| SLMAP | sarcolemma associated protein | 0.0142486 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0142392 |
| CCT6A | chaperonin containing TCP1, subunit 6A (zeta 1) | 0.0142231 |
| RPL21 | ribosomal protein L21 | 0.0142223 |
| RPL7 | ribosomal protein L7 | 0.014214 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0141943 |
| HSPA4 | heat shock 70kDa protein 4 | 0.0140469 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0139126 |
| PSMB2 | proteasome (prosome, macropain) subunit, beta type, 2 | 0.0138262 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.013706 |
| NCKAP1 | NCK-associated protein 1 | 0.0136422 |
| PPME1 | protein phosphatase methylesterase 1 | 0.0135958 |
| DNAJC2 | DnaJ (Hsp40) homolog, subfamily C, member 2 | 0.0135113 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.0133331 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 | 0.0131965 |
| RBM12 | RNA binding motif protein 12 | 0.0131867 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0131373 |
| DSPP | dentin sialophosphoprotein | 0.0130731 |
| KRT5 | keratin 5, type II | 0.0129215 |
| DNTTIP2 | deoxynucleotidyltransferase, terminal, interacting protein 2 | 0.0129099 |
| RACK1 | receptor for activated C kinase 1 | 0.0128977 |
| MT1X | metallothionein 1X | 0.0128699 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | 0.0128513 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0128451 |
| RPL8 | ribosomal protein L8 | 0.0127667 |
| DPM1 | dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit | 0.0127666 |
| CCT5 | chaperonin containing TCP1, subunit 5 (epsilon) | 0.012755 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.240609 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.203232 |
| DPYD | dihydropyrimidine dehydrogenase | -0.11142 |
| MYOF | myoferlin | -0.10686 |
| FOXO1 | forkhead box O1 | -0.0825295 |
| MTSS1 | metastasis suppressor 1 | -0.0824748 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.081069 |
| PRELID2 | PRELI domain containing 2 | -0.0774867 |
| AHNAK | AHNAK nucleoprotein | -0.0700983 |
| OSMR | oncostatin M receptor | -0.0697412 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0696393 |
| FOXP1 | forkhead box P1 | -0.0690383 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0684217 |
| SULF1 | sulfatase 1 | -0.0637273 |
| AOPEP | aminopeptidase O (putative) | -0.0610468 |
| MECOM | MDS1 and EVI1 complex locus | -0.0607983 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0605555 |
| RIN2 | Ras and Rab interactor 2 | -0.0586892 |
| KIAA1217 | KIAA1217 | -0.0584373 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.058082 |
| CD44 | CD44 molecule (Indian blood group) | -0.0564437 |
| SMYD3 | SET and MYND domain containing 3 | -0.0561727 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0547478 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0525983 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 | -0.0523825 |
| NEK7 | NIMA-related kinase 7 | -0.052013 |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 | -0.0493083 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0483238 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0459642 |
| MEF2A | myocyte enhancer factor 2A | -0.0451649 |
| RAD51B | RAD51 paralog B | -0.044231 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.0440619 |
| EFNA5 | ephrin-A5 | -0.0431288 |
| PLEC | plectin | -0.0422388 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.0419402 |
| LMO7 | LIM domain 7 | -0.0415756 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0403553 |
| ITGA6 | integrin, alpha 6 | -0.0397902 |
| NRG1 | neuregulin 1 | -0.0396968 |
| BLCAP | bladder cancer associated protein | -0.0394295 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0390334 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | -0.0389397 |
| BCL2L1 | BCL2-like 1 | -0.0388484 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0388207 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.0378006 |
| PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) | -0.0377865 |
| ANXA2 | annexin A2 | -0.037442 |
| SULF2 | sulfatase 2 | -0.0365707 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | -0.0359625 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0358228 |
| HM13 | histocompatibility (minor) 13 | -0.0358208 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0357908 |
| PALLD | palladin, cytoskeletal associated protein | -0.0354553 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | -0.0354249 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0354021 |
| ADAMTS16 | ADAM metallopeptidase with thrombospondin type 1 motif, 16 | -0.0352828 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | -0.0349408 |
| NDRG1 | N-myc downstream regulated 1 | -0.0348779 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.0345362 |
| ACTN4 | actinin, alpha 4 | -0.0340267 |
| TMSB4X | thymosin beta 4, X-linked | -0.0338882 |
| SMAD3 | SMAD family member 3 | -0.0338452 |
| GNAS | GNAS complex locus | -0.0334184 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0333862 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0332236 |
| EXOC4 | exocyst complex component 4 | -0.0332189 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.033196 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0327848 |
| METTL15 | methyltransferase like 15 | -0.0325621 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0321258 |
| CNTNAP3 | contactin associated protein-like 3 | -0.0320815 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0318406 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | -0.0316388 |
| PRSS23 | protease, serine, 23 | -0.0313475 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0307434 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0305895 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0305442 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0304127 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0302413 |
| RIGI | RNA sensor RIG-I | -0.0302318 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0302242 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.029403 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.029248 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0292195 |
| VCL | vinculin | -0.0291132 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0289948 |
| ATXN1 | ataxin 1 | -0.0289399 |
| DOK5 | docking protein 5 | -0.0289088 |
| ASPH | aspartate beta-hydroxylase | -0.0285986 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0285796 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0276297 |
| NDE1 | nudE neurodevelopment protein 1 | -0.0274652 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0274084 |
| C4BPB | complement component 4 binding protein, beta | -0.027222 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.027182 |
| DOCK9 | dedicator of cytokinesis 9 | -0.0270763 |
| NCOA3 | nuclear receptor coactivator 3 | -0.0269252 |
| SBF2 | SET binding factor 2 | -0.0264495 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.026432 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | -0.0263297 |
