| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ixazomib citrate perturbation in J82 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ixazomib citrate_J82 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0750713 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0618698 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0606801 |
| HSPA1B | heat shock 70kDa protein 1B | 0.057107 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0401008 |
| UBC | ubiquitin C | 0.0301904 |
| TMF1 | TATA element modulatory factor 1 | 0.0271764 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0268162 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | 0.0262741 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0259945 |
| FAM219A | family with sequence similarity 219, member A | 0.0224478 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0223204 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0204744 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0198929 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0194627 |
| ARRDC3 | arrestin domain containing 3 | 0.0191739 |
| MSN | moesin | 0.0187098 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 | 0.018364 |
| RBM12 | RNA binding motif protein 12 | 0.0179215 |
| VMP1 | vacuole membrane protein 1 | 0.01774 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0175149 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0160291 |
| UBQLN1 | ubiquilin 1 | 0.0158447 |
| TAPBP | TAP binding protein (tapasin) | 0.0150759 |
| ABHD3 | abhydrolase domain containing 3 | 0.0150275 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0139556 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0139452 |
| CNBP | CCHC-type zinc finger, nucleic acid binding protein | 0.0138577 |
| TMA7 | translation machinery associated 7 homolog (S. cerevisiae) | 0.013721 |
| UBXN4 | UBX domain protein 4 | 0.0133855 |
| ECPAS | Ecm29 proteasome adaptor and scaffold | 0.0132784 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0131425 |
| GOLGB1 | golgin B1 | 0.0128798 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | 0.0128237 |
| CTNNBL1 | catenin, beta like 1 | 0.0124858 |
| H1-4 | H1.4 linker histone, cluster member | 0.0123696 |
| BRD2 | bromodomain containing 2 | 0.0120965 |
| BAG3 | BCL2-associated athanogene 3 | 0.0120649 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0120618 |
| EIF2AK1 | eukaryotic translation initiation factor 2-alpha kinase 1 | 0.0120357 |
| SPTY2D1 | SPT2, Suppressor of Ty, domain containing 1 (S. cerevisiae) | 0.0119658 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0118324 |
| CAMSAP1 | calmodulin regulated spectrin-associated protein 1 | 0.0117122 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.011604 |
| HSPA4 | heat shock 70kDa protein 4 | 0.0115696 |
| RND3 | Rho family GTPase 3 | 0.0115375 |
| ZFAND5 | zinc finger, AN1-type domain 5 | 0.0115349 |
| GNGT1 | guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 | 0.0112519 |
| GOLGA2 | golgin A2 | 0.0111904 |
| ZNF841 | zinc finger protein 841 | 0.0110242 |
| BOD1L1 | biorientation of chromosomes in cell division 1-like 1 | 0.010827 |
| SLFN11 | schlafen family member 11 | 0.0107714 |
| BCAP31 | B-cell receptor-associated protein 31 | 0.0106481 |
| CHORDC1 | cysteine and histidine-rich domain (CHORD) containing 1 | 0.0105331 |
| TSR1 | TSR1, 20S rRNA accumulation, homolog (S. cerevisiae) | 0.0105328 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | 0.0104208 |
| NARS1 | asparaginyl-tRNA synthetase 1 | 0.0103376 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.0103261 |
| VCP | valosin containing protein | 0.0102884 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0102725 |
| SQSTM1 | sequestosome 1 | 0.0102185 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0102133 |
| ELOVL5 | ELOVL fatty acid elongase 5 | 0.0100495 |
| PSMD11 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 | 0.0100043 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.00989391 |
| PSMD2 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 | 0.00986928 |
| SART1 | squamous cell carcinoma antigen recognized by T cells | 0.0098477 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.00981409 |
| DNAJC2 | DnaJ (Hsp40) homolog, subfamily C, member 2 | 0.00979555 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.00974095 |
| COPB1 | coatomer protein complex, subunit beta 1 | 0.00961981 |
| LSG1 | large 60S subunit nuclear export GTPase 1 | 0.00960893 |
| ZBTB11 | zinc finger and BTB domain containing 11 | 0.00959971 |
| HIBCH | 3-hydroxyisobutyryl-CoA hydrolase | 0.00956371 |
| LEMD3 | LEM domain containing 3 | 0.00952066 |
| VPS35 | vacuolar protein sorting 35 homolog (S. cerevisiae) | 0.00937897 |
| CALCOCO2 | calcium binding and coiled-coil domain 2 | 0.00931878 |
| SUCO | SUN domain containing ossification factor | 0.00931153 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.00902175 |
| SMC1A | structural maintenance of chromosomes 1A | 0.00898678 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.00880698 |
| DNTTIP2 | deoxynucleotidyltransferase, terminal, interacting protein 2 | 0.00879996 |
| NCKAP1 | NCK-associated protein 1 | 0.00878594 |
| OPTN | optineurin | 0.00878486 |
| KIF21A | kinesin family member 21A | 0.00867437 |
| CACYBP | calcyclin binding protein | 0.00865123 |
| USP14 | ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) | 0.00860825 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | 0.00852444 |
| TCP1 | t-complex 1 | 0.00852126 |
| SPICE1 | spindle and centriole associated protein 1 | 0.0084675 |
| DNAJC7 | DnaJ (Hsp40) homolog, subfamily C, member 7 | 0.00845934 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.00845624 |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) | 0.00821352 |
| SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) | 0.00816424 |
| SMARCA5 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 | 0.0081593 |
| ATP2C1 | ATPase, Ca++ transporting, type 2C, member 1 | 0.00813267 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.00808316 |
| SQLE | squalene epoxidase | 0.00807871 |
| RANBP2 | RAN binding protein 2 | 0.00804802 |
| DLGAP3 | discs, large (Drosophila) homolog-associated protein 3 | 0.0080315 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HLA-B | major histocompatibility complex, class I, B | -0.167196 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.166913 |
| EXT1 | exostosin glycosyltransferase 1 | -0.149434 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.143824 |
| FN1 | fibronectin 1 | -0.135956 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.133992 |
| FNDC3B | fibronectin type III domain containing 3B | -0.123501 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.10336 |
| CD44 | CD44 molecule (Indian blood group) | -0.0992711 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0837172 |
| FTL | ferritin, light polypeptide | -0.0819993 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.074361 |
| DEK | DEK proto-oncogene | -0.0736319 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0731549 |
| ANXA2 | annexin A2 | -0.0689096 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.068568 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0675306 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0658777 |
| ERBIN | erbb2 interacting protein | -0.0645626 |
| OSMR | oncostatin M receptor | -0.0620908 |
| NDRG1 | N-myc downstream regulated 1 | -0.0613063 |
| DIAPH3 | diaphanous-related formin 3 | -0.0608123 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0600208 |
| PKM | pyruvate kinase, muscle | -0.0586538 |
| TXNRD1 | thioredoxin reductase 1 | -0.0573321 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0548182 |
| LDHA | lactate dehydrogenase A | -0.0542109 |
| HLA-A | major histocompatibility complex, class I, A | -0.0539248 |
| ATP13A3 | ATPase type 13A3 | -0.0537562 |
| ACTG1 | actin gamma 1 | -0.0529316 |
| TPM1 | tropomyosin 1 (alpha) | -0.0509332 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0504249 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0490246 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0487438 |
| PTK2 | protein tyrosine kinase 2 | -0.0486402 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0485667 |
| POTEF | POTE ankyrin domain family, member F | -0.0481737 |
| ENO1 | enolase 1, (alpha) | -0.047848 |
| CCBE1 | collagen and calcium binding EGF domains 1 | -0.0473785 |
| TMSB10 | thymosin beta 10 | -0.0471354 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.047056 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0469639 |
| ZNF432 | zinc finger protein 432 | -0.0467797 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0467024 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0465738 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0464201 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0448309 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0435226 |
| SMYD3 | SET and MYND domain containing 3 | -0.0427411 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0425089 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0423154 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0418754 |
| VEGFC | vascular endothelial growth factor C | -0.0417361 |
| TUBB | tubulin, beta class I | -0.0411769 |
| ASPH | aspartate beta-hydroxylase | -0.0400101 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0381852 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0377185 |
| MT2A | metallothionein 2A | -0.0369947 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0368732 |
| GLIS3 | GLIS family zinc finger 3 | -0.0362156 |
| HMGB1 | high mobility group box 1 | -0.0361498 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0361035 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.035868 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0356915 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0353846 |
| CTSD | cathepsin D | -0.0352247 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0345633 |
| FLNB | filamin B, beta | -0.0345194 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.034454 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.034421 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0341703 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0340685 |
| VIM | vimentin | -0.0336513 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0333093 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0331574 |
| POSTN | periostin, osteoblast specific factor | -0.0330375 |
| VGLL3 | vestigial-like family member 3 | -0.0329553 |
| HEG1 | heart development protein with EGF-like domains 1 | -0.032503 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0324864 |
| CCND1 | cyclin D1 | -0.0324806 |
| SMAD3 | SMAD family member 3 | -0.0321089 |
| PLCB4 | phospholipase C, beta 4 | -0.0320463 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0312434 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.030502 |
| KRT7 | keratin 7, type II | -0.0303799 |
| NSD2 | nuclear receptor binding SET domain protein 2 | -0.0301344 |
| IL6ST | interleukin 6 signal transducer | -0.0299769 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.029975 |
| NEK7 | NIMA-related kinase 7 | -0.0296423 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0295934 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | -0.0291779 |
| GNAS | GNAS complex locus | -0.0291437 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0287735 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0287562 |
| FOXP1 | forkhead box P1 | -0.0285685 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0283975 |
| PRELID2 | PRELI domain containing 2 | -0.028348 |
| RBM39 | RNA binding motif protein 39 | -0.0282282 |
| PRRC2A | proline-rich coiled-coil 2A | -0.0282006 |
| RPLP1 | ribosomal protein, large, P1 | -0.0279956 |
