| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ixazomib citrate perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ixazomib citrate_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TXNIP | thioredoxin interacting protein | 0.0679382 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0598379 |
| FAM13A | family with sequence similarity 13, member A | 0.0589443 |
| AREG | amphiregulin | 0.0558773 |
| DSPP | dentin sialophosphoprotein | 0.0539652 |
| EREG | epiregulin | 0.0523241 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0510457 |
| RPS3 | ribosomal protein S3 | 0.0490343 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0477926 |
| UBC | ubiquitin C | 0.0457937 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0452365 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0424898 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.040883 |
| NCKAP1 | NCK-associated protein 1 | 0.0396526 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0365666 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0364942 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0359225 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0340299 |
| RBM39 | RNA binding motif protein 39 | 0.033385 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0328225 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0319586 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0311522 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0298764 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0288868 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0287934 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0285084 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | 0.0280296 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0279267 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | 0.0266502 |
| TMSB4X | thymosin beta 4, X-linked | 0.026359 |
| OGA | O-GlcNAcase | 0.026311 |
| H1-0 | H1.0 linker histone | 0.0260491 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0255115 |
| TMF1 | TATA element modulatory factor 1 | 0.0253572 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0253316 |
| RNF145 | ring finger protein 145 | 0.0250874 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0249545 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0248799 |
| AFDN | afadin, adherens junction formation factor | 0.0245843 |
| EZR | ezrin | 0.0245234 |
| GOLGA4 | golgin A4 | 0.0241751 |
| NAP1L4 | nucleosome assembly protein 1-like 4 | 0.0238962 |
| TPM3 | tropomyosin 3 | 0.0232359 |
| TIAL1 | TIA1 cytotoxic granule-associated RNA binding protein-like 1 | 0.0226997 |
| USP47 | ubiquitin specific peptidase 47 | 0.0226574 |
| SERINC1 | serine incorporator 1 | 0.0221455 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0220255 |
| RAB6A | RAB6A, member RAS oncogene family | 0.021623 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0214176 |
| RPL14 | ribosomal protein L14 | 0.021335 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0208514 |
| PCBP2 | poly(rC) binding protein 2 | 0.0207378 |
| CCNY | cyclin Y | 0.0205306 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.0205022 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0204562 |
| EHF | ets homologous factor | 0.0203989 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0202542 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0198223 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0197828 |
| CD47 | CD47 molecule | 0.0197428 |
| FDPS | farnesyl diphosphate synthase | 0.019713 |
| ABI1 | abl-interactor 1 | 0.0195443 |
| PLEKHA2 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2 | 0.0195069 |
| TM9SF2 | transmembrane 9 superfamily member 2 | 0.0194317 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | 0.0192276 |
| AHNAK | AHNAK nucleoprotein | 0.0189367 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0188816 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 0.0184554 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0184477 |
| HELZ | helicase with zinc finger | 0.018372 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0183663 |
| TMA7 | translation machinery associated 7 homolog (S. cerevisiae) | 0.0183008 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | 0.0182898 |
| CDC42BPB | CDC42 binding protein kinase beta (DMPK-like) | 0.018182 |
| YME1L1 | YME1-like 1 ATPase | 0.0177812 |
| PSAT1 | phosphoserine aminotransferase 1 | 0.0177441 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.0176973 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0176796 |
| HADHA | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit | 0.0176087 |
| YTHDC1 | YTH domain containing 1 | 0.0175686 |
| LRRC1 | leucine rich repeat containing 1 | 0.0175456 |
| TPR | translocated promoter region, nuclear basket protein | 0.0175144 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0174019 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0173138 |
| CALR | calreticulin | 0.0171027 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0170242 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0169794 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0168198 |
| LMO7 | LIM domain 7 | 0.0168111 |
| TXNRD1 | thioredoxin reductase 1 | 0.0165517 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0164947 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0164412 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0164057 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0163428 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0162639 |
| WDR45B | WD repeat domain 45B | 0.0161453 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0161018 |
| COPA | coatomer protein complex, subunit alpha | 0.0160745 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0160191 |
| CALCOCO2 | calcium binding and coiled-coil domain 2 | 0.0160165 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NPSR1 | neuropeptide S receptor 1 | -0.154237 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.150178 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.149135 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.140468 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.136344 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.129986 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.129638 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.109675 |
| MYO1E | myosin IE | -0.10772 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0984203 |
| GPHN | gephyrin | -0.094058 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | -0.0927697 |
| TMSB10 | thymosin beta 10 | -0.0853745 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0803381 |
| ACTG1 | actin gamma 1 | -0.0785065 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | -0.076015 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0749247 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0725771 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0701557 |
| CADPS | Ca++-dependent secretion activator | -0.069837 |
| VCL | vinculin | -0.0658657 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0647844 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.064343 |
| TNS4 | tensin 4 | -0.0639789 |
| FHIT | fragile histidine triad | -0.0597655 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0589 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0582695 |
| RPLP1 | ribosomal protein, large, P1 | -0.0553072 |
| SMYD3 | SET and MYND domain containing 3 | -0.0544804 |
| HMGA1 | high mobility group AT-hook 1 | -0.0542217 |
| GREB1L | growth regulation by estrogen in breast cancer-like | -0.0537976 |
| FAT1 | FAT atypical cadherin 1 | -0.0480395 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0468361 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0458318 |
| RAD51B | RAD51 paralog B | -0.045403 |
| ANXA2 | annexin A2 | -0.0436978 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0429411 |
| FOXP1 | forkhead box P1 | -0.0424833 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0423605 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0422115 |
| FTL | ferritin, light polypeptide | -0.041841 |
| TPM4 | tropomyosin 4 | -0.0417192 |
| RPL35A | ribosomal protein L35a | -0.0414655 |
| CCND1 | cyclin D1 | -0.0414141 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0413524 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.040895 |
| MUC17 | mucin 17, cell surface associated | -0.0405534 |
| POTEF | POTE ankyrin domain family, member F | -0.0404892 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0388843 |
| EHBP1 | EH domain binding protein 1 | -0.0388245 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.037978 |
| PKP2 | plakophilin 2 | -0.0369045 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0367213 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0365271 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | -0.0363633 |
| PKM | pyruvate kinase, muscle | -0.0363129 |
| PARD3B | par-3 family cell polarity regulator beta | -0.0362454 |
| DIAPH2 | diaphanous-related formin 2 | -0.0356595 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0354263 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | -0.0352789 |
| RPS24 | ribosomal protein S24 | -0.0352559 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0350472 |
| EGFR | epidermal growth factor receptor | -0.0341973 |
| NRXN3 | neurexin 3 | -0.0341159 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0338934 |
| ACTN4 | actinin, alpha 4 | -0.0328952 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.032696 |
| POF1B | premature ovarian failure, 1B | -0.0326021 |
| TRIM2 | tripartite motif containing 2 | -0.0322495 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0320618 |
| HMGB1 | high mobility group box 1 | -0.0319105 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0318059 |
| ONECUT3 | one cut homeobox 3 | -0.0316823 |
| SAMD5 | sterile alpha motif domain containing 5 | -0.0315037 |
| IER3 | immediate early response 3 | -0.0314672 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.0311657 |
| MECOM | MDS1 and EVI1 complex locus | -0.0309802 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0308277 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.0304859 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0302928 |
| SVIL | supervillin | -0.0300553 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | -0.0300422 |
| RNF217 | ring finger protein 217 | -0.0299985 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0296233 |
| RPS25 | ribosomal protein S25 | -0.0295777 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | -0.0291016 |
| SH3D19 | SH3 domain containing 19 | -0.0290851 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0283172 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0281241 |
| MSI2 | musashi RNA-binding protein 2 | -0.0281129 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0279319 |
| EXOC4 | exocyst complex component 4 | -0.0272109 |
| KRT18 | keratin 18, type I | -0.0271319 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.027042 |
| LSAMP | limbic system-associated membrane protein | -0.0269714 |
| PKP4 | plakophilin 4 | -0.0267986 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0267535 |
| RAB10 | RAB10, member RAS oncogene family | -0.0267321 |
| MED13 | mediator complex subunit 13 | -0.0265786 |
| MUC13 | mucin 13, cell surface associated | -0.026533 |
