| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ixazomib citrate perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Ixazomib citrate_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.183346 |
| GOLGA4 | golgin A4 | 0.131707 |
| CD44 | CD44 molecule (Indian blood group) | 0.127359 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0796023 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.076876 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0687856 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0649725 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0642141 |
| VMP1 | vacuole membrane protein 1 | 0.0609968 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0602621 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0600914 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.055537 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0500381 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.04899 |
| SIK3 | SIK family kinase 3 | 0.048252 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0465855 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.04638 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0453333 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0449441 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.044052 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0439393 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0437773 |
| VIM | vimentin | 0.0436569 |
| UBC | ubiquitin C | 0.0432077 |
| OPTN | optineurin | 0.0430505 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0426799 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0424966 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0423219 |
| SETD5 | SET domain containing 5 | 0.0420421 |
| PTMA | prothymosin, alpha | 0.0419703 |
| RIOK3 | RIO kinase 3 | 0.0409635 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0404729 |
| TPR | translocated promoter region, nuclear basket protein | 0.0404401 |
| COPA | coatomer protein complex, subunit alpha | 0.0403236 |
| FAM107B | family with sequence similarity 107, member B | 0.0382047 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0377405 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0368576 |
| OGA | O-GlcNAcase | 0.0368179 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0355177 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.034694 |
| USP47 | ubiquitin specific peptidase 47 | 0.0343962 |
| ATP13A3 | ATPase type 13A3 | 0.0338376 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0338011 |
| RPS6 | ribosomal protein S6 | 0.0333649 |
| GDI2 | GDP dissociation inhibitor 2 | 0.0329571 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0329303 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0324161 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0322809 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | 0.0319597 |
| RNF24 | ring finger protein 24 | 0.0318861 |
| NKTR | natural killer cell triggering receptor | 0.0318781 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0315697 |
| SRP54 | signal recognition particle 54kDa | 0.0310854 |
| GLG1 | golgi glycoprotein 1 | 0.0308 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0304212 |
| RBM25 | RNA binding motif protein 25 | 0.0303722 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0302401 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.030234 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0302193 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0299787 |
| ARRDC3 | arrestin domain containing 3 | 0.0299177 |
| IL1R1 | interleukin 1 receptor, type I | 0.0297092 |
| RND3 | Rho family GTPase 3 | 0.0291693 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0289001 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0287255 |
| TGM2 | transglutaminase 2 | 0.0284772 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0281676 |
| OS9 | osteosarcoma amplified 9, endoplasmic reticulum lectin | 0.0281417 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0280541 |
| SFTPA2 | surfactant protein A2 | 0.0278658 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.0273313 |
| ANKRD17 | ankyrin repeat domain 17 | 0.027224 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.0271377 |
| KYNU | kynureninase | 0.0269075 |
| TAPBP | TAP binding protein (tapasin) | 0.0269064 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0267901 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.026703 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0266294 |
| CLINT1 | clathrin interactor 1 | 0.0262678 |
| RDX | radixin | 0.0261985 |
| OXSR1 | oxidative stress responsive 1 | 0.026141 |
| MIB1 | mindbomb E3 ubiquitin protein ligase 1 | 0.0261211 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0260418 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0259681 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0257324 |
| TMEM263 | transmembrane protein 263 | 0.0256633 |
| ELP2 | elongator acetyltransferase complex subunit 2 | 0.025643 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0256048 |
| TMSB10 | thymosin beta 10 | 0.0255076 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0254422 |
| CEP350 | centrosomal protein 350kDa | 0.0254068 |
| FBXL13 | F-box and leucine-rich repeat protein 13 | 0.0250676 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | 0.0250547 |
| ECPAS | Ecm29 proteasome adaptor and scaffold | 0.0250348 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0250293 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0249984 |
| CTDSP2 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2 | 0.0249702 |
| BRD2 | bromodomain containing 2 | 0.0249596 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0249577 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.024948 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.144234 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.134846 |
| CDH13 | cadherin 13 | -0.113581 |
| NRG1 | neuregulin 1 | -0.108588 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.104766 |
| EFNA5 | ephrin-A5 | -0.0963489 |
| HMGA2 | high mobility group AT-hook 2 | -0.0930501 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | -0.0807927 |
| MTSS1 | metastasis suppressor 1 | -0.0745644 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0659915 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0658909 |
| LOX | lysyl oxidase | -0.0608537 |
| FAM20C | family with sequence similarity 20, member C | -0.0591152 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0551089 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0544528 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0492796 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0450901 |
| GPC6 | glypican 6 | -0.0446062 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0445112 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.0414447 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0409278 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0389149 |
| PKM | pyruvate kinase, muscle | -0.0385143 |
| GALNT18 | polypeptide N-acetylgalactosaminyltransferase 18 | -0.0382628 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0380908 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0376796 |
| EFCAB13 | EF-hand calcium binding domain 13 | -0.0374702 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0364497 |
| PRELID2 | PRELI domain containing 2 | -0.0364412 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0356142 |
| IFI44L | interferon-induced protein 44-like | -0.0354484 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0353082 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | -0.0352675 |
| INTS6 | integrator complex subunit 6 | -0.0349841 |
| FN1 | fibronectin 1 | -0.0342382 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0337311 |
| SQSTM1 | sequestosome 1 | -0.0336268 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0335212 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0335199 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0333004 |
| SP100 | SP100 nuclear antigen | -0.0330033 |
| NHSL1 | NHS-like 1 | -0.0328139 |
| MX1 | MX dynamin-like GTPase 1 | -0.0326713 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0325758 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0314162 |
| ATG7 | autophagy related 7 | -0.0311137 |
| NABP1 | nucleic acid binding protein 1 | -0.0306988 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0303448 |
| ASPH | aspartate beta-hydroxylase | -0.0300231 |
| FBN1 | fibrillin 1 | -0.029525 |
| HPCAL1 | hippocalcin-like 1 | -0.0293358 |
| RNF213 | ring finger protein 213 | -0.0286093 |
| HMGA1 | high mobility group AT-hook 1 | -0.0283409 |
| DTNA | dystrobrevin, alpha | -0.0280679 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0280013 |
| ZNF292 | zinc finger protein 292 | -0.0279275 |
| NRP1 | neuropilin 1 | -0.0277868 |
| DNER | delta/notch-like EGF repeat containing | -0.027364 |
| RAD51B | RAD51 paralog B | -0.0270907 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0269912 |
| MEF2A | myocyte enhancer factor 2A | -0.0268919 |
| GLIS3 | GLIS family zinc finger 3 | -0.0265384 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0264995 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0261645 |
| RPLP1 | ribosomal protein, large, P1 | -0.0261033 |
| NAV2 | neuron navigator 2 | -0.0259235 |
| CFAP20DC | CFAP20 domain containing | -0.0256346 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.0255941 |
| SUMF1 | sulfatase modifying factor 1 | -0.0254616 |
| NDRG1 | N-myc downstream regulated 1 | -0.0253019 |
| FRMD4A | FERM domain containing 4A | -0.0251475 |
| PNPT1 | polyribonucleotide nucleotidyltransferase 1 | -0.0250462 |
| ENOSF1 | enolase superfamily member 1 | -0.0248693 |
| SH3RF3 | SH3 domain containing ring finger 3 | -0.0247887 |
| PRKCA | protein kinase C, alpha | -0.0245171 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0244317 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0240123 |
| CDK14 | cyclin-dependent kinase 14 | -0.0235941 |
| DIAPH2 | diaphanous-related formin 2 | -0.0235913 |
| AADAC | arylacetamide deacetylase | -0.0234687 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0229119 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0219244 |
| ZNF804A | zinc finger protein 804A | -0.0218574 |
| DENND1A | DENN/MADD domain containing 1A | -0.0217632 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0217377 |
| YBX1 | Y box binding protein 1 | -0.021718 |
| HDAC4 | histone deacetylase 4 | -0.0216729 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0215142 |
| PTPRB | protein tyrosine phosphatase, receptor type, B | -0.0214587 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.0213869 |
| GNGT1 | guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 | -0.0213693 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | -0.0212942 |
| RIGI | RNA sensor RIG-I | -0.0208887 |
| ETV6 | ets variant 6 | -0.0208447 |
| TMTC1 | transmembrane and tetratricopeptide repeat containing 1 | -0.0208367 |
| DMXL1 | Dmx-like 1 | -0.0205856 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0205227 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | -0.0202413 |
| SLC41A2 | solute carrier family 41 (magnesium transporter), member 2 | -0.0202345 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0202085 |
