| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ixazomib citrate perturbation in NCI-H2347 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Ixazomib citrate_NCI-H2347 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.124747 |
| ASPH | aspartate beta-hydroxylase | 0.0959611 |
| POTEF | POTE ankyrin domain family, member F | 0.0959081 |
| NDRG1 | N-myc downstream regulated 1 | 0.0893132 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0785583 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0774388 |
| FTL | ferritin, light polypeptide | 0.0771339 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0711026 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0707952 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0665511 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0617649 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0583873 |
| RNF145 | ring finger protein 145 | 0.0563046 |
| LAMB3 | laminin, beta 3 | 0.0551348 |
| EZR | ezrin | 0.0549994 |
| RBM25 | RNA binding motif protein 25 | 0.0533257 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0527229 |
| CTSB | cathepsin B | 0.0510777 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0508702 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0503006 |
| MSN | moesin | 0.0497856 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0496803 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0493289 |
| TXNRD1 | thioredoxin reductase 1 | 0.0488956 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0488858 |
| FAM3C | family with sequence similarity 3, member C | 0.0483931 |
| TFG | TRK-fused gene | 0.0472643 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0470085 |
| TXNIP | thioredoxin interacting protein | 0.0468958 |
| PTMA | prothymosin, alpha | 0.0468742 |
| SLMAP | sarcolemma associated protein | 0.046594 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0464913 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0463889 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0447413 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0443343 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0436894 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0428368 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0421738 |
| LAMC2 | laminin, gamma 2 | 0.0404811 |
| RBM39 | RNA binding motif protein 39 | 0.0395656 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0387404 |
| FAM162A | family with sequence similarity 162, member A | 0.0386995 |
| NCKAP1 | NCK-associated protein 1 | 0.0382744 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0377547 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0376426 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0373544 |
| MT2A | metallothionein 2A | 0.0373013 |
| PGK1 | phosphoglycerate kinase 1 | 0.037078 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0365896 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0357914 |
| RIOK3 | RIO kinase 3 | 0.0356141 |
| DSPP | dentin sialophosphoprotein | 0.0355193 |
| MATR3 | matrin 3 | 0.0354589 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0350413 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0345071 |
| TPM3 | tropomyosin 3 | 0.0342849 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0342303 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0336023 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | 0.033239 |
| MIER1 | mesoderm induction early response 1, transcriptional regulator | 0.0331776 |
| SDC4 | syndecan 4 | 0.0328715 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.032428 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0321551 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | 0.0321528 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0318895 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | 0.0312436 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0309161 |
| ATP13A3 | ATPase type 13A3 | 0.0308502 |
| UBC | ubiquitin C | 0.0308432 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | 0.0307068 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0306714 |
| SREK1IP1 | SREK1-interacting protein 1 | 0.0294773 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0293735 |
| YBX3 | Y box binding protein 3 | 0.0292458 |
| DSG2 | desmoglein 2 | 0.0289362 |
| CCNL1 | cyclin L1 | 0.0288201 |
| H1-0 | H1.0 linker histone | 0.0286559 |
| MAP1B | microtubule-associated protein 1B | 0.0285327 |
| SFTPA2 | surfactant protein A2 | 0.0282982 |
| MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | 0.0278115 |
| DUSP10 | dual specificity phosphatase 10 | 0.0276515 |
| CD47 | CD47 molecule | 0.0274717 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0271488 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0271477 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0268883 |
| FNBP1L | formin binding protein 1-like | 0.0268032 |
| USP3 | ubiquitin specific peptidase 3 | 0.0261957 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0259616 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0252716 |
| PCBP2 | poly(rC) binding protein 2 | 0.0251772 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0249681 |
| CALR | calreticulin | 0.0241515 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.024134 |
| RTN4 | reticulon 4 | 0.0239233 |
| GPX4 | glutathione peroxidase 4 | 0.0238158 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0238008 |
| WAC | WW domain containing adaptor with coiled-coil | 0.023717 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0235697 |
| CNBP | CCHC-type zinc finger, nucleic acid binding protein | 0.023513 |
| SEPTIN7 | septin 7 | 0.023475 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SAMD4A | sterile alpha motif domain containing 4A | -0.174693 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.147323 |
| EXT1 | exostosin glycosyltransferase 1 | -0.146384 |
| EFNA5 | ephrin-A5 | -0.110817 |
| ACTG1 | actin gamma 1 | -0.0967398 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.095368 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0946352 |
| VCL | vinculin | -0.0876277 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0834201 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.081849 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.078898 |
| FNIP1 | folliculin interacting protein 1 | -0.0767944 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0762824 |
| MYO1E | myosin IE | -0.0743087 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0682752 |
| INTS6 | integrator complex subunit 6 | -0.0664568 |
| FBXO34 | F-box protein 34 | -0.0660169 |
| NAV2 | neuron navigator 2 | -0.064586 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0638669 |
| CANX | calnexin | -0.0625917 |
| PALLD | palladin, cytoskeletal associated protein | -0.0618123 |
| ARHGAP20 | Rho GTPase activating protein 20 | -0.0610451 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0593454 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.056858 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0536662 |
| RPL9 | ribosomal protein L9 | -0.0529241 |
| RPL35A | ribosomal protein L35a | -0.0525712 |
| RCOR1 | REST corepressor 1 | -0.0520788 |
| FNDC3B | fibronectin type III domain containing 3B | -0.051626 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0511039 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0488935 |
| RPS25 | ribosomal protein S25 | -0.04787 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0471075 |
| CD109 | CD109 molecule | -0.0465858 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0462719 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0460731 |
| CDK13 | cyclin-dependent kinase 13 | -0.0459022 |
| GNAS | GNAS complex locus | -0.0454985 |
| MICAL3 | microtubule associated monooxygenase, calponin and LIM domain containing 3 | -0.0439134 |
| RPS24 | ribosomal protein S24 | -0.0435186 |
| CTBP2 | C-terminal binding protein 2 | -0.0429183 |
| RPL23 | ribosomal protein L23 | -0.0427814 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0414451 |
| CERT1 | ceramide transporter 1 | -0.0407571 |
| RPL30 | ribosomal protein L30 | -0.0405424 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0403775 |
| GOLGB1 | golgin B1 | -0.0397254 |
| RPL34 | ribosomal protein L34 | -0.0391538 |
| DPYSL2 | dihydropyrimidinase-like 2 | -0.0388408 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0385782 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0385763 |
| CEP350 | centrosomal protein 350kDa | -0.0385728 |
| PPP1R13B | protein phosphatase 1, regulatory subunit 13B | -0.0385021 |
| RPLP0 | ribosomal protein, large, P0 | -0.0383634 |
| UBAP1 | ubiquitin associated protein 1 | -0.0379687 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.0376363 |
| TAOK1 | TAO kinase 1 | -0.037221 |
| OCLN | occludin | -0.0371849 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0369113 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0368705 |
| RPLP1 | ribosomal protein, large, P1 | -0.0368072 |
| RPS13 | ribosomal protein S13 | -0.0358807 |
| ARF4 | ADP-ribosylation factor 4 | -0.0357138 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0356942 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | -0.0356 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0354334 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | -0.0353772 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0347357 |
| SMAD3 | SMAD family member 3 | -0.0346954 |
| ARF1 | ADP-ribosylation factor 1 | -0.0342559 |
| TJP1 | tight junction protein 1 | -0.0341926 |
| RPS23 | ribosomal protein S23 | -0.0339069 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0337483 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0335404 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0335292 |
| LRCH3 | leucine-rich repeats and calponin homology (CH) domain containing 3 | -0.0333328 |
| FAM114A1 | family with sequence similarity 114, member A1 | -0.0332825 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0328669 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0325268 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0324897 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0320014 |
| NF1 | neurofibromin 1 | -0.0318611 |
| RAB5A | RAB5A, member RAS oncogene family | -0.031676 |
| KDM4B | lysine (K)-specific demethylase 4B | -0.031499 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0314729 |
| EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) | -0.0313969 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0312877 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0307884 |
| SCFD1 | sec1 family domain containing 1 | -0.0306461 |
| ATOSA | atos homolog A | -0.0305207 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0304698 |
| LOXL2 | lysyl oxidase-like 2 | -0.0297114 |
| ATP11A | ATPase, class VI, type 11A | -0.0293565 |
| CLIC4 | chloride intracellular channel 4 | -0.0293318 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0289404 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0283773 |
| USP53 | ubiquitin specific peptidase 53 | -0.0282413 |
| FAM193A | family with sequence similarity 193, member A | -0.0281036 |
| MAP3K13 | mitogen-activated protein kinase kinase kinase 13 | -0.0280922 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0280199 |
