| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ixazomib citrate perturbation in NCI-H596 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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118 genes differentially expressed following the Ixazomib citrate_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.406048 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.147444 |
| GPC6 | glypican 6 | 0.1351 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | 0.132013 |
| HSPA8 | heat shock 70kDa protein 8 | 0.128516 |
| UBC | ubiquitin C | 0.115426 |
| SYT1 | synaptotagmin I | 0.0932591 |
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | 0.0911986 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0881654 |
| VMP1 | vacuole membrane protein 1 | 0.087833 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0872912 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0833536 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0822694 |
| ZNF292 | zinc finger protein 292 | 0.0814215 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0765776 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0712472 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0697972 |
| MEIS2 | Meis homeobox 2 | 0.065805 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0647143 |
| RPS4X | ribosomal protein S4, X-linked | 0.0642953 |
| ANO6 | anoctamin 6 | 0.0633407 |
| PAPOLA | poly(A) polymerase alpha | 0.0618028 |
| RBM39 | RNA binding motif protein 39 | 0.0609002 |
| RPS27 | ribosomal protein S27 | 0.0599471 |
| RPL7 | ribosomal protein L7 | 0.0568156 |
| JMJD1C | jumonji domain containing 1C | 0.0545037 |
| PRRC2C | proline-rich coiled-coil 2C | 0.054407 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.0535451 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0522408 |
| PTK2 | protein tyrosine kinase 2 | 0.0495711 |
| RUNX1 | runt-related transcription factor 1 | 0.0484182 |
| AGFG1 | ArfGAP with FG repeats 1 | 0.0480617 |
| SPAG9 | sperm associated antigen 9 | 0.0443798 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0430111 |
| GOLGB1 | golgin B1 | 0.0402071 |
| ARRDC3 | arrestin domain containing 3 | 0.0400255 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0397218 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0388568 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0332766 |
| RPS3 | ribosomal protein S3 | 0.0329523 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0317457 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0312886 |
| FTL | ferritin, light polypeptide | 0.0309408 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0304807 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0296467 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0279706 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0267888 |
| POTEF | POTE ankyrin domain family, member F | 0.023949 |
| PGK1 | phosphoglycerate kinase 1 | 0.0216403 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0186213 |
| GOLGA4 | golgin A4 | 0.0181392 |
| RPL11 | ribosomal protein L11 | 0.0158995 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0131782 |
| CADM2 | cell adhesion molecule 2 | 0.0105507 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | 0.00695192 |
| RPL12 | ribosomal protein L12 | 0.00542194 |
| PEG10 | paternally expressed 10 | 0.00375069 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.002473 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TRIO | trio Rho guanine nucleotide exchange factor | -0.263136 |
| EXT1 | exostosin glycosyltransferase 1 | -0.246886 |
| HMGA2 | high mobility group AT-hook 2 | -0.18366 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.160816 |
| MT2A | metallothionein 2A | -0.150683 |
| VIM | vimentin | -0.142226 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.133801 |
| NDRG1 | N-myc downstream regulated 1 | -0.128163 |
| PDE10A | phosphodiesterase 10A | -0.122818 |
| TMSB10 | thymosin beta 10 | -0.116842 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.114679 |
| STC1 | stanniocalcin 1 | -0.113128 |
| FN1 | fibronectin 1 | -0.110504 |
| CDH13 | cadherin 13 | -0.106153 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.100556 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0897095 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.080084 |
| MYO1E | myosin IE | -0.0800529 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0780305 |
| EFNA5 | ephrin-A5 | -0.0762695 |
| LDHA | lactate dehydrogenase A | -0.0754083 |
| MCL1 | myeloid cell leukemia 1 | -0.0700152 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0680431 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0661324 |
| RPS25 | ribosomal protein S25 | -0.0628549 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0582673 |
| SMYD3 | SET and MYND domain containing 3 | -0.0557102 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0551106 |
| NAV2 | neuron navigator 2 | -0.0507204 |
| VCL | vinculin | -0.0480113 |
| RORA | RAR-related orphan receptor A | -0.0435046 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0403563 |
| DST | dystonin | -0.0368785 |
| PTMA | prothymosin, alpha | -0.0344073 |
| RPS8 | ribosomal protein S8 | -0.0318891 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0318783 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0304993 |
| RPLP1 | ribosomal protein, large, P1 | -0.0292559 |
| RPS6 | ribosomal protein S6 | -0.0284972 |
| RPS19 | ribosomal protein S19 | -0.0279347 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0263554 |
| RPS12 | ribosomal protein S12 | -0.0262831 |
| ENO1 | enolase 1, (alpha) | -0.0261603 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.024106 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0219361 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0204842 |
| RPL23 | ribosomal protein L23 | -0.0189948 |
| ATP11A | ATPase, class VI, type 11A | -0.0180754 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0179447 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0176601 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0152354 |
| ASPH | aspartate beta-hydroxylase | -0.0136199 |
| ATXN1 | ataxin 1 | -0.0114914 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0107536 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.00548296 |
| ANXA2 | annexin A2 | -0.00540465 |
| EGFR | epidermal growth factor receptor | -0.00387201 |
| CANX | calnexin | -0.00379888 |
| IGF2 | insulin-like growth factor 2 | -0.00226404 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.00126597 |
