| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ixazomib citrate perturbation in PANC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Ixazomib citrate_PANC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ZFP36 | ZFP36 ring finger protein | 0.226694 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.203059 |
| FTL | ferritin, light polypeptide | 0.158737 |
| PSMC4 | proteasome (prosome, macropain) 26S subunit, ATPase, 4 | 0.125212 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.119714 |
| UBC | ubiquitin C | 0.115056 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0819656 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0711281 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0565387 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0502154 |
| RPS3 | ribosomal protein S3 | 0.0496244 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0469482 |
| SAMD4B | sterile alpha motif domain containing 4B | 0.0462828 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0454745 |
| PTMA | prothymosin, alpha | 0.0453849 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.044548 |
| SFTPA2 | surfactant protein A2 | 0.0436845 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0406108 |
| SPAG9 | sperm associated antigen 9 | 0.0394497 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0380167 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0378233 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0371447 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.035927 |
| YBX1 | Y box binding protein 1 | 0.0347439 |
| UPP1 | uridine phosphorylase 1 | 0.0346326 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0334124 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.031749 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0314253 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | 0.030789 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0291384 |
| VCP | valosin containing protein | 0.0284075 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0281875 |
| PSMD2 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 | 0.0267667 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0262815 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0260296 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0253278 |
| RACK1 | receptor for activated C kinase 1 | 0.0250372 |
| ADM | adrenomedullin | 0.0242413 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0240447 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | 0.0238285 |
| TAPBP | TAP binding protein (tapasin) | 0.0238116 |
| PSMD13 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 | 0.0233949 |
| RPS2 | ribosomal protein S2 | 0.0231008 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0226314 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0225589 |
| TIAL1 | TIA1 cytotoxic granule-associated RNA binding protein-like 1 | 0.0221893 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.021991 |
| PSMD11 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 | 0.0215349 |
| MSN | moesin | 0.0213644 |
| SQSTM1 | sequestosome 1 | 0.0208798 |
| RPS12 | ribosomal protein S12 | 0.0208574 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0208186 |
| RIOK3 | RIO kinase 3 | 0.0205416 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0205015 |
| USP3 | ubiquitin specific peptidase 3 | 0.0199119 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.019378 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0193253 |
| ARRDC3 | arrestin domain containing 3 | 0.0192904 |
| TFG | TRK-fused gene | 0.0188606 |
| TMEM41B | transmembrane protein 41B | 0.0188521 |
| ATP13A3 | ATPase type 13A3 | 0.0187659 |
| PAF1 | Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) | 0.0187264 |
| NCKAP1 | NCK-associated protein 1 | 0.0186497 |
| RPS8 | ribosomal protein S8 | 0.0184265 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0184258 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0183375 |
| PSMC6 | proteasome (prosome, macropain) 26S subunit, ATPase, 6 | 0.0182193 |
| CANX | calnexin | 0.0180832 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0177292 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0176995 |
| RPL14 | ribosomal protein L14 | 0.0176409 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0175438 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0172312 |
| TPM3 | tropomyosin 3 | 0.0170973 |
| BRD2 | bromodomain containing 2 | 0.0170734 |
| RPL3 | ribosomal protein L3 | 0.0168991 |
| TXNRD1 | thioredoxin reductase 1 | 0.0168345 |
| MAP1B | microtubule-associated protein 1B | 0.0167376 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0166452 |
| UBQLN1 | ubiquilin 1 | 0.0166214 |
| SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) | 0.0165817 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | 0.0165271 |
| CNBP | CCHC-type zinc finger, nucleic acid binding protein | 0.0164711 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0164033 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0163349 |
| NOP58 | NOP58 ribonucleoprotein | 0.0162913 |
| VEZT | vezatin, adherens junctions transmembrane protein | 0.0162482 |
| DNAJC2 | DnaJ (Hsp40) homolog, subfamily C, member 2 | 0.0160923 |
| SET | SET nuclear proto-oncogene | 0.0160009 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0159526 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0158159 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | 0.01576 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.015657 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0155788 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0155604 |
| UBB | ubiquitin B | 0.0154811 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0150359 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0148143 |
| HADHA | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit | 0.0146641 |
| WDR45B | WD repeat domain 45B | 0.0146179 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.206379 |
| VCL | vinculin | -0.100746 |
| CD44 | CD44 molecule (Indian blood group) | -0.0827146 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0634134 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0582923 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0572713 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0565509 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0559969 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0557744 |
| TMSB10 | thymosin beta 10 | -0.0553014 |
| RPS16 | ribosomal protein S16 | -0.0543874 |
| AHNAK | AHNAK nucleoprotein | -0.0543684 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0527634 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0505101 |
| DST | dystonin | -0.0491047 |
| JMJD1C | jumonji domain containing 1C | -0.0483739 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0483369 |
| CARD18 | caspase recruitment domain family, member 18 | -0.0480368 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0462768 |
| ACTN4 | actinin, alpha 4 | -0.0425691 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0425637 |
| EGFR | epidermal growth factor receptor | -0.0425063 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0413162 |
| HMGA2 | high mobility group AT-hook 2 | -0.0401323 |
| EXT1 | exostosin glycosyltransferase 1 | -0.039458 |
| TMEM123 | transmembrane protein 123 | -0.0391095 |
| NF1 | neurofibromin 1 | -0.0381373 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0376115 |
| PHF14 | PHD finger protein 14 | -0.0370074 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0364145 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.035631 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0352923 |
| ATXN1 | ataxin 1 | -0.0352644 |
| RPS24 | ribosomal protein S24 | -0.0350983 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0349438 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0345827 |
| SBF2 | SET binding factor 2 | -0.0340195 |
| TNS3 | tensin 3 | -0.0340145 |
| ACTG1 | actin gamma 1 | -0.033274 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0328883 |
| ATG7 | autophagy related 7 | -0.0328189 |
| SMYD3 | SET and MYND domain containing 3 | -0.0327078 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0326476 |
| S100A6 | S100 calcium binding protein A6 | -0.0324769 |
| PDE10A | phosphodiesterase 10A | -0.032256 |
| FBXO17 | F-box protein 17 | -0.0315584 |
| AFAP1 | actin filament associated protein 1 | -0.0314808 |
| RASAL2 | RAS protein activator like 2 | -0.0314677 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0307078 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0306024 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0302933 |
| CDK19 | cyclin-dependent kinase 19 | -0.0302778 |
| MYOF | myoferlin | -0.0300092 |
| MYO10 | myosin X | -0.0297801 |
| EHBP1 | EH domain binding protein 1 | -0.0291727 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0291337 |
| RNF220 | ring finger protein 220 | -0.0290097 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0287405 |
| USP34 | ubiquitin specific peptidase 34 | -0.0287203 |
| MED29 | mediator complex subunit 29 | -0.0283313 |
| EFNA5 | ephrin-A5 | -0.0282773 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0279723 |
| ERBIN | erbb2 interacting protein | -0.0278472 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0277115 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0272208 |
| RNF213 | ring finger protein 213 | -0.0271034 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | -0.0270589 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | -0.0267555 |
| CDK13 | cyclin-dependent kinase 13 | -0.026358 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0261374 |
| OSMR | oncostatin M receptor | -0.0261188 |
| ANXA2 | annexin A2 | -0.0260555 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0259872 |
| MT2A | metallothionein 2A | -0.0259718 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.0257314 |
| NUP98 | nucleoporin 98kDa | -0.0255871 |
| ZNF780B | zinc finger protein 780B | -0.0252354 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0251745 |
| FHL2 | four and a half LIM domains 2 | -0.0251483 |
| NHSL1 | NHS-like 1 | -0.0248898 |
| CDK6 | cyclin-dependent kinase 6 | -0.0248207 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.024687 |
| CTSD | cathepsin D | -0.0246582 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0246491 |
| RAD51B | RAD51 paralog B | -0.0246406 |
| ITGAV | integrin, alpha V | -0.0242818 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0241503 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.023401 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.0233843 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.023136 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0231021 |
| RSF1 | remodeling and spacing factor 1 | -0.0230604 |
| MED13L | mediator complex subunit 13-like | -0.0230295 |
| DIAPH2 | diaphanous-related formin 2 | -0.0230267 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0230214 |
| HMGA1 | high mobility group AT-hook 1 | -0.023 |
| PTK2 | protein tyrosine kinase 2 | -0.0228302 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0226905 |
| TPM1 | tropomyosin 1 (alpha) | -0.0224454 |
| PRSS23 | protease, serine, 23 | -0.0223971 |
