| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ixazomib citrate perturbation in RPMI-7951 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Ixazomib citrate_RPMI-7951 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.240028 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.114147 |
| FTL | ferritin, light polypeptide | 0.109238 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0612934 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.05799 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0452731 |
| MSN | moesin | 0.0450297 |
| MT2A | metallothionein 2A | 0.0416262 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0404117 |
| UBC | ubiquitin C | 0.0364109 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0361704 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0351108 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0344927 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0330145 |
| MKI67 | marker of proliferation Ki-67 | 0.0321802 |
| CENPF | centromere protein F, 350/400kDa | 0.0310406 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0306415 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.029922 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0284561 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | 0.027964 |
| RPS6 | ribosomal protein S6 | 0.0272341 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0254485 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0241812 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0226228 |
| TAPBP | TAP binding protein (tapasin) | 0.0226152 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | 0.0224046 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0212743 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0212469 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0212085 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0210492 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0210368 |
| RPS3 | ribosomal protein S3 | 0.0209602 |
| CNBP | CCHC-type zinc finger, nucleic acid binding protein | 0.0209583 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0207002 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.020694 |
| TPM3 | tropomyosin 3 | 0.0201654 |
| VCP | valosin containing protein | 0.0201317 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0201115 |
| ARRDC3 | arrestin domain containing 3 | 0.0193121 |
| ANLN | anillin, actin binding protein | 0.0190192 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0183748 |
| SERINC1 | serine incorporator 1 | 0.0178181 |
| YBX1 | Y box binding protein 1 | 0.0177458 |
| RPL14 | ribosomal protein L14 | 0.0176238 |
| APP | amyloid beta (A4) precursor protein | 0.0172119 |
| TPX2 | TPX2, microtubule-associated | 0.0171911 |
| XPO1 | exportin 1 | 0.017 |
| TMA7 | translation machinery associated 7 homolog (S. cerevisiae) | 0.0168643 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.0168193 |
| SMAD3 | SMAD family member 3 | 0.0166581 |
| CKAP2 | cytoskeleton associated protein 2 | 0.0166547 |
| CTSB | cathepsin B | 0.0164758 |
| SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) | 0.0164282 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0161349 |
| PSMD11 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 | 0.0159264 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | 0.0155436 |
| UBXN4 | UBX domain protein 4 | 0.0154033 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0153922 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0152574 |
| UBQLN1 | ubiquilin 1 | 0.015255 |
| RPS12 | ribosomal protein S12 | 0.0152247 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0150857 |
| ARPP19 | cAMP-regulated phosphoprotein, 19kDa | 0.0150691 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0149654 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0148762 |
| BUB1B | BUB1 mitotic checkpoint serine/threonine kinase B | 0.0148373 |
| SET | SET nuclear proto-oncogene | 0.0142205 |
| SNAPC1 | small nuclear RNA activating complex, polypeptide 1, 43kDa | 0.0141413 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.014092 |
| PDAP1 | PDGFA associated protein 1 | 0.0140898 |
| H1-4 | H1.4 linker histone, cluster member | 0.0140816 |
| PSMD2 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 | 0.0140339 |
| NSFL1C | NSFL1 (p97) cofactor (p47) | 0.0138241 |
| HSPB1 | heat shock 27kDa protein 1 | 0.0137765 |
| PSMD1 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 | 0.0137459 |
| NLRP1 | NLR family, pyrin domain containing 1 | 0.013611 |
| PSMC6 | proteasome (prosome, macropain) 26S subunit, ATPase, 6 | 0.0135276 |
| ANGPTL4 | angiopoietin-like 4 | 0.0134347 |
| RPS19 | ribosomal protein S19 | 0.013406 |
| HADHA | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit | 0.0133569 |
| PSMB2 | proteasome (prosome, macropain) subunit, beta type, 2 | 0.0132119 |
| TMF1 | TATA element modulatory factor 1 | 0.0129461 |
| ZFR | zinc finger RNA binding protein | 0.0129285 |
| SFTPA2 | surfactant protein A2 | 0.0129119 |
| HSPE1 | heat shock 10kDa protein 1 | 0.012863 |
| HSPA1A | heat shock 70kDa protein 1A | 0.0128354 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0127922 |
| NONO | non-POU domain containing, octamer-binding | 0.0127835 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.012782 |
| WBP11 | WW domain binding protein 11 | 0.0127513 |
| PPME1 | protein phosphatase methylesterase 1 | 0.0127272 |
| RPL18 | ribosomal protein L18 | 0.0126949 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0125965 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.0124974 |
| RPL12 | ribosomal protein L12 | 0.012494 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0124822 |
| FYTTD1 | forty-two-three domain containing 1 | 0.0124343 |
| ABHD3 | abhydrolase domain containing 3 | 0.0123087 |
| NCKAP1 | NCK-associated protein 1 | 0.0122253 |
| ZC3H3 | zinc finger CCCH-type containing 3 | 0.0122226 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.312155 |
| FN1 | fibronectin 1 | -0.30909 |
| COL1A2 | collagen, type I, alpha 2 | -0.146037 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.144144 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.133544 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0948828 |
| COL1A1 | collagen, type I, alpha 1 | -0.0942924 |
| FRMD4A | FERM domain containing 4A | -0.071261 |
| NRP1 | neuropilin 1 | -0.0659 |
| PKM | pyruvate kinase, muscle | -0.0643153 |
| TMSB10 | thymosin beta 10 | -0.0628828 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0593689 |
| CDH13 | cadherin 13 | -0.0587116 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0554631 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0539618 |
| HLA-B | major histocompatibility complex, class I, B | -0.0537532 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0527465 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.048705 |
| NDRG1 | N-myc downstream regulated 1 | -0.0478317 |
| NAV1 | neuron navigator 1 | -0.0477006 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0471142 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0470637 |
| TPM4 | tropomyosin 4 | -0.0460286 |
| EGR1 | early growth response 1 | -0.0454806 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.045371 |
| SP100 | SP100 nuclear antigen | -0.0451839 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0447943 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.04474 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0440518 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0433818 |
| HM13 | histocompatibility (minor) 13 | -0.0425588 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0421381 |
| TMEM178B | transmembrane protein 178B | -0.0416521 |
| RRBP1 | ribosome binding protein 1 | -0.0415847 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0407359 |
| TPM1 | tropomyosin 1 (alpha) | -0.040265 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0375679 |
| POTEF | POTE ankyrin domain family, member F | -0.0369984 |
| GOLGA4 | golgin A4 | -0.0369168 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0366076 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0359249 |
| CLIC4 | chloride intracellular channel 4 | -0.0351199 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0350453 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0348897 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0347868 |
| INHBA | inhibin, beta A | -0.0340209 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0336955 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0336333 |
| CALU | calumenin | -0.0332374 |
| MAP4 | microtubule-associated protein 4 | -0.0331442 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0329949 |
| SEC24D | SEC24 family member D | -0.0329861 |
| ACTG1 | actin gamma 1 | -0.032907 |
| ATXN1 | ataxin 1 | -0.0327791 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0324212 |
| IER3 | immediate early response 3 | -0.0322717 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0322494 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0318547 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0315231 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0312463 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0306586 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0305051 |
| S100A6 | S100 calcium binding protein A6 | -0.030489 |
| TNS3 | tensin 3 | -0.0303907 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0303828 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0298457 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0294237 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0289975 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0289757 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0289558 |
| GNAS | GNAS complex locus | -0.0285754 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0284989 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0284408 |
| RPLP1 | ribosomal protein, large, P1 | -0.0283247 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0281286 |
| TCF12 | transcription factor 12 | -0.0280943 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0280369 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.02802 |
| GLIS3 | GLIS family zinc finger 3 | -0.028016 |
| CHD9 | chromodomain helicase DNA binding protein 9 | -0.0278676 |
| HMGA2 | high mobility group AT-hook 2 | -0.0278548 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0278165 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0274662 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0272766 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0270234 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | -0.0267662 |
| APCDD1L | adenomatosis polyposis coli down-regulated 1-like | -0.0266901 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0265832 |
| LOX | lysyl oxidase | -0.0264432 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0262254 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0261824 |
| COL5A1 | collagen, type V, alpha 1 | -0.0260329 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0259101 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0258071 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0256986 |
| ITGA11 | integrin, alpha 11 | -0.0255163 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0254758 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0252129 |
| FBN1 | fibrillin 1 | -0.0251627 |
| COL5A2 | collagen, type V, alpha 2 | -0.025129 |
