| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ixazomib citrate perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Ixazomib citrate_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | 0.208482 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.144308 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.123371 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.10189 |
| TMSB4X | thymosin beta 4, X-linked | 0.0937593 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0924458 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0792918 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0656602 |
| RPS6 | ribosomal protein S6 | 0.0631521 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0600712 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0575247 |
| ANXA1 | annexin A1 | 0.0520093 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.049946 |
| FTL | ferritin, light polypeptide | 0.0480726 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0472513 |
| RPS8 | ribosomal protein S8 | 0.0470283 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0468071 |
| GOLGA4 | golgin A4 | 0.0465489 |
| RPS3 | ribosomal protein S3 | 0.0435671 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0426753 |
| ECT2 | epithelial cell transforming 2 | 0.0422104 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0414538 |
| B2M | beta-2-microglobulin | 0.0390257 |
| SQSTM1 | sequestosome 1 | 0.0379591 |
| PGK1 | phosphoglycerate kinase 1 | 0.0371585 |
| RACK1 | receptor for activated C kinase 1 | 0.0367401 |
| CALR | calreticulin | 0.0354668 |
| MKI67 | marker of proliferation Ki-67 | 0.0352791 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0347985 |
| LDHA | lactate dehydrogenase A | 0.0343578 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0340468 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | 0.0332841 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0328291 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.032662 |
| EZR | ezrin | 0.0326382 |
| DSTN | destrin (actin depolymerizing factor) | 0.0293093 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.029174 |
| RPS2 | ribosomal protein S2 | 0.0288904 |
| ENO1 | enolase 1, (alpha) | 0.0288407 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0287268 |
| HMGB2 | high mobility group box 2 | 0.0285884 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0283961 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0278492 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0274419 |
| SET | SET nuclear proto-oncogene | 0.0271443 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.026978 |
| RPL12 | ribosomal protein L12 | 0.0269385 |
| BRD2 | bromodomain containing 2 | 0.0266839 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0262013 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.025676 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.025312 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0248961 |
| AHNAK | AHNAK nucleoprotein | 0.0247998 |
| KIF5B | kinesin family member 5B | 0.0246513 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0246481 |
| CENPF | centromere protein F, 350/400kDa | 0.0245124 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.0241976 |
| TPX2 | TPX2, microtubule-associated | 0.0240136 |
| SFTPA2 | surfactant protein A2 | 0.0239328 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0238012 |
| TXNIP | thioredoxin interacting protein | 0.0237092 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0236621 |
| CANX | calnexin | 0.023651 |
| RPL14 | ribosomal protein L14 | 0.0235781 |
| TPM4 | tropomyosin 4 | 0.0235004 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.023409 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.022801 |
| APP | amyloid beta (A4) precursor protein | 0.0225147 |
| RPL34 | ribosomal protein L34 | 0.0224437 |
| RPS27A | ribosomal protein S27a | 0.0222347 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0222276 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0219465 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0211798 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0207737 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0207545 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0206462 |
| ASPH | aspartate beta-hydroxylase | 0.020549 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0203683 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0201637 |
| RPL19 | ribosomal protein L19 | 0.0199525 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.0198254 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.019669 |
| HDLBP | high density lipoprotein binding protein | 0.0196609 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | 0.019642 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0194479 |
| RPL7 | ribosomal protein L7 | 0.0188107 |
| RPL37 | ribosomal protein L37 | 0.0183901 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0183676 |
| TPR | translocated promoter region, nuclear basket protein | 0.0183456 |
| QKI | QKI, KH domain containing, RNA binding | 0.0182801 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0182336 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0182192 |
| RPS19 | ribosomal protein S19 | 0.0181896 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | 0.0180223 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0179852 |
| MYOF | myoferlin | 0.0179653 |
| RPL35A | ribosomal protein L35a | 0.0178942 |
| PLK2 | polo-like kinase 2 | 0.0178106 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 0.0176691 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0176668 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0677311 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0555727 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0553282 |
| EML4 | echinoderm microtubule associated protein like 4 | -0.0449672 |
| PDGFC | platelet derived growth factor C | -0.0438566 |
| EGFR | epidermal growth factor receptor | -0.0437296 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.0404079 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0366066 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0341992 |
| NBEA | neurobeachin | -0.0315053 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0306819 |
| GLI2 | GLI family zinc finger 2 | -0.029924 |
| FOXP1 | forkhead box P1 | -0.0293837 |
| TMEM65 | transmembrane protein 65 | -0.0293431 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0292991 |
| TJP1 | tight junction protein 1 | -0.0290545 |
| PKM | pyruvate kinase, muscle | -0.0279995 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0277932 |
| PYGB | phosphorylase, glycogen; brain | -0.0274185 |
| VCL | vinculin | -0.0265544 |
| ADAM10 | ADAM metallopeptidase domain 10 | -0.0253122 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0248796 |
| SOX6 | SRY (sex determining region Y)-box 6 | -0.0246357 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0246333 |
| ANK2 | ankyrin 2, neuronal | -0.0241024 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0234735 |
| SMYD3 | SET and MYND domain containing 3 | -0.0233454 |
| EFNA5 | ephrin-A5 | -0.0226069 |
| TXNRD1 | thioredoxin reductase 1 | -0.0214178 |
| CCND1 | cyclin D1 | -0.0205162 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0201504 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0197471 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 | -0.0195994 |
| GLI3 | GLI family zinc finger 3 | -0.0195683 |
| HEG1 | heart development protein with EGF-like domains 1 | -0.0189463 |
| SPRY4 | sprouty homolog 4 (Drosophila) | -0.0187718 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0185273 |
| MAP3K14 | mitogen-activated protein kinase kinase kinase 14 | -0.0185023 |
| HDAC9 | histone deacetylase 9 | -0.0178941 |
| CAMKMT | calmodulin-lysine N-methyltransferase | -0.016973 |
| PTEN | phosphatase and tensin homolog | -0.016851 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 | -0.0165275 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0164633 |
| DOCK3 | dedicator of cytokinesis 3 | -0.0160038 |
| RTN4 | reticulon 4 | -0.0158028 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0156378 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0155998 |
| PRELID2 | PRELI domain containing 2 | -0.0155905 |
| LOXL3 | lysyl oxidase-like 3 | -0.0153244 |
| ATP9B | ATPase, class II, type 9B | -0.0153109 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | -0.0152794 |
| JMJD1C | jumonji domain containing 1C | -0.0152793 |
| ADNP | activity-dependent neuroprotector homeobox | -0.0151022 |
| OSMR | oncostatin M receptor | -0.0150335 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0149608 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0149152 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | -0.0149062 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0148483 |
| RUSC2 | RUN and SH3 domain containing 2 | -0.0148008 |
| PARD3B | par-3 family cell polarity regulator beta | -0.0145943 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | -0.0145078 |
| ZNHIT6 | zinc finger, HIT-type containing 6 | -0.0144162 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0142651 |
| FHAD1 | forkhead-associated (FHA) phosphopeptide binding domain 1 | -0.0142257 |
| FLNB | filamin B, beta | -0.0140251 |
| GCNT1 | glucosaminyl (N-acetyl) transferase 1, core 2 | -0.0138856 |
| PPM1L | protein phosphatase, Mg2+/Mn2+ dependent, 1L | -0.0137995 |
| MYO5C | myosin VC | -0.0136688 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.013595 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0134103 |
| KLF3 | Kruppel-like factor 3 (basic) | -0.0133793 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0133328 |
| SPIDR | scaffolding protein involved in DNA repair | -0.0130819 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0129721 |
| ALDH3A2 | aldehyde dehydrogenase 3 family, member A2 | -0.0129683 |
| SESN2 | sestrin 2 | -0.0128939 |
| DIAPH2 | diaphanous-related formin 2 | -0.0126364 |
| WDR43 | WD repeat domain 43 | -0.0126076 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide | -0.0123551 |
| ZNF207 | zinc finger protein 207 | -0.0122908 |
| TMSB10 | thymosin beta 10 | -0.0122606 |
| MACROD2 | MACRO domain containing 2 | -0.012189 |
| PHF14 | PHD finger protein 14 | -0.0121879 |
| ARB2A | ARB2 cotranscriptional regulator A | -0.012136 |
| EXOC6B | exocyst complex component 6B | -0.0121282 |
| PIWIL1 | piwi-like RNA-mediated gene silencing 1 | -0.0119979 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0119504 |
| RAD51B | RAD51 paralog B | -0.0118565 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0117898 |
| MLIP | muscular LMNA-interacting protein | -0.0117832 |
| EVI5 | ecotropic viral integration site 5 | -0.0117608 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | -0.0117173 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0116218 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0114717 |
| PTBP2 | polypyrimidine tract binding protein 2 | -0.0114194 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.0113485 |
| PRUNE2 | prune homolog 2 (Drosophila) | -0.011293 |
| PARD3 | par-3 family cell polarity regulator | -0.0112595 |
| PNPT1 | polyribonucleotide nucleotidyltransferase 1 | -0.011259 |
| RAB27B | RAB27B, member RAS oncogene family | -0.0109326 |
