| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ixazomib citrate perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ixazomib citrate_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.249756 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.203764 |
| HSPA8 | heat shock 70kDa protein 8 | 0.109622 |
| UBC | ubiquitin C | 0.0738503 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0672365 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0603582 |
| HSPA1A | heat shock 70kDa protein 1A | 0.0594003 |
| RND3 | Rho family GTPase 3 | 0.0569258 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0559338 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0550988 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 | 0.0545426 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0449858 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0407784 |
| VMP1 | vacuole membrane protein 1 | 0.0384264 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0367677 |
| HSPA1B | heat shock 70kDa protein 1B | 0.03401 |
| SQSTM1 | sequestosome 1 | 0.0324566 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0320173 |
| RPS3 | ribosomal protein S3 | 0.0314193 |
| TAPBP | TAP binding protein (tapasin) | 0.0313226 |
| KIF1B | kinesin family member 1B | 0.0310745 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0304187 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0285827 |
| RPS6 | ribosomal protein S6 | 0.0278447 |
| MAP1B | microtubule-associated protein 1B | 0.0274371 |
| SFTPA2 | surfactant protein A2 | 0.0270527 |
| ARRDC3 | arrestin domain containing 3 | 0.0263555 |
| TXNRD1 | thioredoxin reductase 1 | 0.0251542 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0248427 |
| CTSB | cathepsin B | 0.0245038 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0240901 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0238463 |
| FAM219A | family with sequence similarity 219, member A | 0.0237981 |
| SLC38A1 | solute carrier family 38, member 1 | 0.0236963 |
| MSN | moesin | 0.0236671 |
| BRD2 | bromodomain containing 2 | 0.0236656 |
| TPM3 | tropomyosin 3 | 0.0234467 |
| TCP1 | t-complex 1 | 0.0228927 |
| PSMD1 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 | 0.0228903 |
| ZFAND5 | zinc finger, AN1-type domain 5 | 0.0226764 |
| RPL14 | ribosomal protein L14 | 0.0223111 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0219989 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0218745 |
| ECPAS | Ecm29 proteasome adaptor and scaffold | 0.0214917 |
| ADM | adrenomedullin | 0.0212383 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0204045 |
| BAG3 | BCL2-associated athanogene 3 | 0.0203584 |
| TUSC3 | tumor suppressor candidate 3 | 0.020034 |
| APP | amyloid beta (A4) precursor protein | 0.0197057 |
| TMF1 | TATA element modulatory factor 1 | 0.0193757 |
| B2M | beta-2-microglobulin | 0.0193151 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.019294 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0189168 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0186983 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0185484 |
| OPTN | optineurin | 0.018334 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | 0.0179953 |
| PTMA | prothymosin, alpha | 0.0179069 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0177753 |
| SERINC1 | serine incorporator 1 | 0.0176195 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | 0.0174479 |
| HSPA4 | heat shock 70kDa protein 4 | 0.017374 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0173269 |
| UBQLN1 | ubiquilin 1 | 0.01702 |
| PNN | pinin, desmosome associated protein | 0.0169889 |
| NCKAP1 | NCK-associated protein 1 | 0.0169756 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0169719 |
| OGA | O-GlcNAcase | 0.0169282 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.016925 |
| NPLOC4 | nuclear protein localization 4 homolog (S. cerevisiae) | 0.0168309 |
| RBM25 | RNA binding motif protein 25 | 0.0167346 |
| TIAL1 | TIA1 cytotoxic granule-associated RNA binding protein-like 1 | 0.016669 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.016635 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0165968 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0163057 |
| MKI67 | marker of proliferation Ki-67 | 0.0161631 |
| FNIP1 | folliculin interacting protein 1 | 0.0160977 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0160398 |
| CALCOCO2 | calcium binding and coiled-coil domain 2 | 0.0160262 |
| USP47 | ubiquitin specific peptidase 47 | 0.0157866 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0157116 |
| WAPL | WAPL cohesin release factor | 0.015529 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0155205 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0153996 |
| KIF21A | kinesin family member 21A | 0.0152189 |
| SDC4 | syndecan 4 | 0.0152185 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0151919 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0150312 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0149786 |
| DNTTIP2 | deoxynucleotidyltransferase, terminal, interacting protein 2 | 0.0145578 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0145051 |
| SLMAP | sarcolemma associated protein | 0.0144108 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0143651 |
| NAP1L4 | nucleosome assembly protein 1-like 4 | 0.0141932 |
| RPS12 | ribosomal protein S12 | 0.0141691 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0140817 |
| RBM12 | RNA binding motif protein 12 | 0.0139937 |
| MORF4L2 | mortality factor 4 like 2 | 0.0139846 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | 0.0139636 |
| PCBP2 | poly(rC) binding protein 2 | 0.0139182 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FRMD4A | FERM domain containing 4A | -0.103483 |
| BICC1 | BicC family RNA binding protein 1 | -0.0983488 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0958776 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0948018 |
| VCL | vinculin | -0.0916631 |
| VIM | vimentin | -0.0914568 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0866857 |
| GLIS3 | GLIS family zinc finger 3 | -0.0849493 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0827918 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0776954 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0766528 |
| FN1 | fibronectin 1 | -0.0761289 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.072132 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0719055 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0649443 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0632829 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0618688 |
| SMAD3 | SMAD family member 3 | -0.0560549 |
| PDE10A | phosphodiesterase 10A | -0.0544364 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0534976 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0534525 |
| HLA-B | major histocompatibility complex, class I, B | -0.0525185 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0514437 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0510109 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0503789 |
| HMGA2 | high mobility group AT-hook 2 | -0.0486569 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0479818 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0473462 |
| TNS3 | tensin 3 | -0.0463185 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0463168 |
| NDRG1 | N-myc downstream regulated 1 | -0.0444998 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0442934 |
| NABP1 | nucleic acid binding protein 1 | -0.0442712 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0439265 |
| CD44 | CD44 molecule (Indian blood group) | -0.0426759 |
| THBS1 | thrombospondin 1 | -0.0425917 |
| RIGI | RNA sensor RIG-I | -0.0414019 |
| RNF213 | ring finger protein 213 | -0.040667 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0405713 |
| KYNU | kynureninase | -0.0403497 |
| TPM1 | tropomyosin 1 (alpha) | -0.0399421 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0392555 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0388158 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0385275 |
| TMSB10 | thymosin beta 10 | -0.0384485 |
| CTSD | cathepsin D | -0.0384332 |
| MX1 | MX dynamin-like GTPase 1 | -0.0375486 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0373714 |
| ZNF292 | zinc finger protein 292 | -0.0365064 |
| OSMR | oncostatin M receptor | -0.0363065 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0361603 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0360582 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0359135 |
| SMYD3 | SET and MYND domain containing 3 | -0.0353956 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0351573 |
| EGR1 | early growth response 1 | -0.034713 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0342965 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0340099 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0338451 |
| TPM4 | tropomyosin 4 | -0.033545 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0334022 |
| ATXN1 | ataxin 1 | -0.0327572 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0316811 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0311235 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0307956 |
| LDHA | lactate dehydrogenase A | -0.0305728 |
| PLSCR1 | phospholipid scramblase 1 | -0.0305623 |
| HMGA1 | high mobility group AT-hook 1 | -0.0303704 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.030122 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0300056 |
| PGK1 | phosphoglycerate kinase 1 | -0.0297471 |
| NAV1 | neuron navigator 1 | -0.0296963 |
| DIAPH2 | diaphanous-related formin 2 | -0.029594 |
| NRP1 | neuropilin 1 | -0.0295025 |
| CLIC4 | chloride intracellular channel 4 | -0.0293445 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0292313 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0288905 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0288375 |
| VCAN | versican | -0.027624 |
| GNAS | GNAS complex locus | -0.0276002 |
| RAD51B | RAD51 paralog B | -0.0273753 |
| IER3 | immediate early response 3 | -0.0272558 |
| ADAM12 | ADAM metallopeptidase domain 12 | -0.0270323 |
| GPC6 | glypican 6 | -0.0269233 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0266998 |
| PALLD | palladin, cytoskeletal associated protein | -0.0266 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | -0.0262237 |
| CDCP1 | CUB domain containing protein 1 | -0.0260193 |
| ERBIN | erbb2 interacting protein | -0.0258603 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0256539 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0252913 |
| SFRP1 | secreted frizzled-related protein 1 | -0.0251378 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0249017 |
| CADM1 | cell adhesion molecule 1 | -0.0247594 |
| ACTG1 | actin gamma 1 | -0.0247445 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.0246109 |
| PMP22 | peripheral myelin protein 22 | -0.0244782 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0242463 |
| SP100 | SP100 nuclear antigen | -0.0239327 |
| CDH13 | cadherin 13 | -0.0238316 |
