| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ixazomib citrate perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ixazomib citrate_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.270105 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.133982 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.115303 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0759709 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0690349 |
| UBC | ubiquitin C | 0.0674749 |
| PTMA | prothymosin, alpha | 0.0670103 |
| CD44 | CD44 molecule (Indian blood group) | 0.0542244 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0533328 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0521871 |
| FTL | ferritin, light polypeptide | 0.0484235 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0478998 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0464892 |
| B2M | beta-2-microglobulin | 0.0443644 |
| MT2A | metallothionein 2A | 0.0425124 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0399444 |
| HSPB1 | heat shock 27kDa protein 1 | 0.0398747 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0363512 |
| H3-3B | H3.3 histone B | 0.0358893 |
| SQSTM1 | sequestosome 1 | 0.0343476 |
| TAPBP | TAP binding protein (tapasin) | 0.0342809 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0330918 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0328286 |
| TXNIP | thioredoxin interacting protein | 0.0326732 |
| CTSB | cathepsin B | 0.0323495 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0322808 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0314903 |
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | 0.0312 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | 0.0307507 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0299177 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0295894 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0295287 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0293731 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0285034 |
| RYBP | RING1 and YY1 binding protein | 0.0284756 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0277302 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0277086 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0271391 |
| ANLN | anillin, actin binding protein | 0.0270511 |
| DIAPH3 | diaphanous-related formin 3 | 0.02682 |
| COL1A2 | collagen, type I, alpha 2 | 0.0267773 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | 0.0265552 |
| ARRDC3 | arrestin domain containing 3 | 0.0264848 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0261736 |
| CD109 | CD109 molecule | 0.0256525 |
| RPS6 | ribosomal protein S6 | 0.0252271 |
| CADM1 | cell adhesion molecule 1 | 0.0251021 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0247844 |
| TXNRD1 | thioredoxin reductase 1 | 0.0246514 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.024644 |
| RPS19 | ribosomal protein S19 | 0.0243306 |
| PNN | pinin, desmosome associated protein | 0.0242028 |
| KIF5B | kinesin family member 5B | 0.0241708 |
| MSN | moesin | 0.0233606 |
| RPL37A | ribosomal protein L37a | 0.0233055 |
| RPS5 | ribosomal protein S5 | 0.0231285 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0231147 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0228118 |
| RPLP0 | ribosomal protein, large, P0 | 0.0225135 |
| JUN | jun proto-oncogene | 0.0224844 |
| TUBA1B | tubulin, alpha 1b | 0.0224421 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0224282 |
| TPM3 | tropomyosin 3 | 0.0224173 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | 0.0221647 |
| IGFBP7 | insulin-like growth factor binding protein 7 | 0.0218731 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0217891 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | 0.0217792 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0216262 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0215435 |
| RNF145 | ring finger protein 145 | 0.0215138 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0213502 |
| PCM1 | pericentriolar material 1 | 0.0212685 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0209993 |
| ANXA1 | annexin A1 | 0.0209904 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0209096 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.020856 |
| SMARCA5 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 | 0.0207814 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0207309 |
| RPL32 | ribosomal protein L32 | 0.0207069 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0206444 |
| IRF1 | interferon regulatory factor 1 | 0.0206246 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0204469 |
| UBXN4 | UBX domain protein 4 | 0.0202315 |
| USP3 | ubiquitin specific peptidase 3 | 0.0202102 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0201397 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0201369 |
| CCNL1 | cyclin L1 | 0.0197463 |
| PCBP2 | poly(rC) binding protein 2 | 0.0194411 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0194328 |
| DSTN | destrin (actin depolymerizing factor) | 0.019209 |
| NCAPG2 | non-SMC condensin II complex, subunit G2 | 0.0191203 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0190622 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0189927 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0189892 |
| HMGA1 | high mobility group AT-hook 1 | 0.0188444 |
| TENT2 | terminal nucleotidyltransferase 2 | 0.0187913 |
| RPS8 | ribosomal protein S8 | 0.0187723 |
| MED10 | mediator complex subunit 10 | 0.0187441 |
| RPL30 | ribosomal protein L30 | 0.0186787 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | 0.0185861 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.200794 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.161946 |
| FN1 | fibronectin 1 | -0.158771 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.155137 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.13668 |
| CDH13 | cadherin 13 | -0.134784 |
| COL6A3 | collagen, type VI, alpha 3 | -0.11302 |
| EGFR | epidermal growth factor receptor | -0.0949146 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0915627 |
| NRXN3 | neurexin 3 | -0.0893486 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0796965 |
| COL5A1 | collagen, type V, alpha 1 | -0.0785966 |
| TNS3 | tensin 3 | -0.075603 |
| PRSS23 | protease, serine, 23 | -0.0748096 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0701977 |
| PRELID2 | PRELI domain containing 2 | -0.069099 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0659337 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0630801 |
| RAI14 | retinoic acid induced 14 | -0.062584 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0616238 |
| AHNAK | AHNAK nucleoprotein | -0.0604692 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0604601 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0598455 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0593732 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0543274 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0513951 |
| STC1 | stanniocalcin 1 | -0.0510398 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0508862 |
| CALU | calumenin | -0.0501855 |
| LOX | lysyl oxidase | -0.0454259 |
| CANX | calnexin | -0.0450778 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0447593 |
| ATXN1 | ataxin 1 | -0.0443287 |
| NAV1 | neuron navigator 1 | -0.0441689 |
| HLA-C | major histocompatibility complex, class I, C | -0.0428093 |
| LOXL2 | lysyl oxidase-like 2 | -0.0424733 |
| CALD1 | caldesmon 1 | -0.0424643 |
| EXOC4 | exocyst complex component 4 | -0.0423896 |
| EFNA5 | ephrin-A5 | -0.0420956 |
| COG6 | component of oligomeric golgi complex 6 | -0.0415364 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0410988 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0404027 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0400844 |
| HMGA2 | high mobility group AT-hook 2 | -0.0400743 |
| CDK13 | cyclin-dependent kinase 13 | -0.0398409 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0394717 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.039358 |
| CHD9 | chromodomain helicase DNA binding protein 9 | -0.0392252 |
| PRKCA | protein kinase C, alpha | -0.0390508 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0387155 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0382985 |
| FBXO11 | F-box protein 11 | -0.0381521 |
| FNIP1 | folliculin interacting protein 1 | -0.0381261 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0374845 |
| VEGFA | vascular endothelial growth factor A | -0.0373836 |
| GLIS3 | GLIS family zinc finger 3 | -0.0372337 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0369328 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0358873 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0357641 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0352837 |
| USP34 | ubiquitin specific peptidase 34 | -0.0349481 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0348192 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | -0.0346213 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.033727 |
| IL6ST | interleukin 6 signal transducer | -0.0336463 |
| KAZN | kazrin, periplakin interacting protein | -0.0336057 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0335881 |
| TMEM165 | transmembrane protein 165 | -0.0334587 |
| HM13 | histocompatibility (minor) 13 | -0.0333047 |
| YIPF5 | Yip1 domain family, member 5 | -0.0332597 |
| FRMD4A | FERM domain containing 4A | -0.032909 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0326585 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0325933 |
| RUNX1 | runt-related transcription factor 1 | -0.0323154 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.032097 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0314819 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0314696 |
| IL6 | interleukin 6 | -0.0312193 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.031189 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0308522 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0304991 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0302364 |
| OSMR | oncostatin M receptor | -0.0301526 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0301115 |
| DNAH11 | dynein, axonemal, heavy chain 11 | -0.0299777 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0299361 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0295286 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.029043 |
| MYLK | myosin light chain kinase | -0.028647 |
| VCL | vinculin | -0.0286072 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0284079 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0283417 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0281846 |
| NCOR2 | nuclear receptor corepressor 2 | -0.0280812 |
| PMM2 | phosphomannomutase 2 | -0.0280619 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0276173 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0274601 |
| AK1 | adenylate kinase 1 | -0.0274454 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0273761 |
| PDIA5 | protein disulfide isomerase family A, member 5 | -0.0273718 |
