| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ixazomib citrate perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ixazomib citrate_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA8 | heat shock 70kDa protein 8 | 0.0800338 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 | 0.0781246 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0677019 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0639727 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0619978 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0574694 |
| CANX | calnexin | 0.053234 |
| UBC | ubiquitin C | 0.0515082 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0494391 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0489275 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0483054 |
| RBM39 | RNA binding motif protein 39 | 0.0472766 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0455923 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | 0.0445098 |
| NKTR | natural killer cell triggering receptor | 0.0430767 |
| CLTC | clathrin, heavy chain (Hc) | 0.0416313 |
| RPS3 | ribosomal protein S3 | 0.0394993 |
| CEP295 | centrosomal protein 295kDa | 0.0388009 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.0380499 |
| GOLGA4 | golgin A4 | 0.0362428 |
| ECPAS | Ecm29 proteasome adaptor and scaffold | 0.0360777 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0354959 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0353404 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0353067 |
| TPX2 | TPX2, microtubule-associated | 0.0349397 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0348612 |
| SERINC1 | serine incorporator 1 | 0.0340617 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0339289 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0329831 |
| CEP250 | centrosomal protein 250kDa | 0.0320956 |
| CASC3 | cancer susceptibility candidate 3 | 0.0314176 |
| RRBP1 | ribosome binding protein 1 | 0.0309851 |
| ARRDC3 | arrestin domain containing 3 | 0.0309124 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0304346 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0300998 |
| OGA | O-GlcNAcase | 0.030026 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0298141 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0298033 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0293931 |
| PTPN11 | protein tyrosine phosphatase, non-receptor type 11 | 0.0293348 |
| SRP54 | signal recognition particle 54kDa | 0.0293088 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.0292245 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0291969 |
| LDHA | lactate dehydrogenase A | 0.0290491 |
| HSPA1A | heat shock 70kDa protein 1A | 0.0286999 |
| ANLN | anillin, actin binding protein | 0.0285625 |
| AFF4 | AF4/FMR2 family, member 4 | 0.028428 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0283942 |
| SCAF11 | SR-related CTD-associated factor 11 | 0.0282921 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0280409 |
| HDLBP | high density lipoprotein binding protein | 0.0276526 |
| COPB1 | coatomer protein complex, subunit beta 1 | 0.0272538 |
| DNMT1 | DNA (cytosine-5-)-methyltransferase 1 | 0.0272476 |
| RANBP2 | RAN binding protein 2 | 0.0272232 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0268576 |
| ANXA1 | annexin A1 | 0.0267348 |
| TMEM263 | transmembrane protein 263 | 0.0265763 |
| CNBP | CCHC-type zinc finger, nucleic acid binding protein | 0.0263211 |
| MAP1B | microtubule-associated protein 1B | 0.0262195 |
| ECT2 | epithelial cell transforming 2 | 0.0258051 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0257571 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0256053 |
| EMSY | EMSY transcriptional repressor, BRCA2 interacting | 0.0255658 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | 0.025565 |
| PPME1 | protein phosphatase methylesterase 1 | 0.0255271 |
| PHF20 | PHD finger protein 20 | 0.0254642 |
| RPLP0 | ribosomal protein, large, P0 | 0.0252887 |
| TNPO3 | transportin 3 | 0.0251239 |
| ANP32A | acidic (leucine-rich) nuclear phosphoprotein 32 family, member A | 0.0249549 |
| RPL14 | ribosomal protein L14 | 0.0247144 |
| BRD2 | bromodomain containing 2 | 0.0247003 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.0243774 |
| RANBP9 | RAN binding protein 9 | 0.0243587 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.024269 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | 0.0242485 |
| STRN | striatin, calmodulin binding protein | 0.0241028 |
| BTBD1 | BTB (POZ) domain containing 1 | 0.0240218 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0238416 |
| BAG3 | BCL2-associated athanogene 3 | 0.0237923 |
| DST | dystonin | 0.023788 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0236457 |
| NUP58 | nucleoporin 58 | 0.0234282 |
| FAM114A1 | family with sequence similarity 114, member A1 | 0.0234274 |
| SSH2 | slingshot protein phosphatase 2 | 0.0233068 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0231999 |
| SYNGAP1 | synaptic Ras GTPase activating protein 1 | 0.0231527 |
| UQCC1 | ubiquinol-cytochrome c reductase complex assembly factor 1 | 0.0228976 |
| UBAC2 | UBA domain containing 2 | 0.022713 |
| HMGB2 | high mobility group box 2 | 0.0226625 |
| PRC1 | protein regulator of cytokinesis 1 | 0.0226277 |
| RPL26 | ribosomal protein L26 | 0.022539 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | 0.0224271 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0222974 |
| CENPF | centromere protein F, 350/400kDa | 0.0222412 |
| TRIM23 | tripartite motif containing 23 | 0.0220012 |
| NDFIP1 | Nedd4 family interacting protein 1 | 0.0218685 |
| AHNAK | AHNAK nucleoprotein | 0.0218278 |
| MEMO1 | mediator of cell motility 1 | 0.021815 |
| RARS1 | arginyl-tRNA synthetase 1 | 0.0217793 |
| ZBTB43 | zinc finger and BTB domain containing 43 | 0.0216229 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.141431 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0965829 |
| TMSB10 | thymosin beta 10 | -0.0790412 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0657071 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0584684 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0560574 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0559207 |
| HMGA2 | high mobility group AT-hook 2 | -0.0559129 |
| OSMR | oncostatin M receptor | -0.0469251 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0457756 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0440829 |
| VCL | vinculin | -0.0439018 |
| PKM | pyruvate kinase, muscle | -0.0427019 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0426719 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0422327 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0414182 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0403333 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0394214 |
| EGR1 | early growth response 1 | -0.0394051 |
| BPTF | bromodomain PHD finger transcription factor | -0.0389494 |
| RPLP1 | ribosomal protein, large, P1 | -0.0378905 |
| NALCN | sodium leak channel, non selective | -0.0375927 |
| GNAS | GNAS complex locus | -0.0372821 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0365646 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0359085 |
| WNK1 | WNK lysine deficient protein kinase 1 | -0.0358816 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0358643 |
| DNER | delta/notch-like EGF repeat containing | -0.0342609 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0340061 |
| USP34 | ubiquitin specific peptidase 34 | -0.0337705 |
| HDAC9 | histone deacetylase 9 | -0.0336763 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0329647 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0324998 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0321818 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0320632 |
| FLNB | filamin B, beta | -0.032002 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0319219 |
| NLK | nemo-like kinase | -0.0318282 |
| INTS6 | integrator complex subunit 6 | -0.0316841 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0300283 |
| NAV2 | neuron navigator 2 | -0.0298822 |
| ETV6 | ets variant 6 | -0.029115 |
| ATG7 | autophagy related 7 | -0.0284359 |
| MCL1 | myeloid cell leukemia 1 | -0.0280439 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0280383 |
| DPYD | dihydropyrimidine dehydrogenase | -0.027966 |
| ANXA2 | annexin A2 | -0.0272581 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0270515 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0269987 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | -0.026932 |
| BSG | basigin (Ok blood group) | -0.0267984 |
| ZNF292 | zinc finger protein 292 | -0.0266113 |
| AOPEP | aminopeptidase O (putative) | -0.0265578 |
| ATG10 | autophagy related 10 | -0.0261674 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.026063 |
| RPL31 | ribosomal protein L31 | -0.0259145 |
| MMP24OS | MMP24 opposite strand | -0.0256827 |
| PCNX4 | pecanex 4 | -0.0255059 |
| RIGI | RNA sensor RIG-I | -0.0254118 |
| ARMH4 | armadillo like helical domain containing 4 | -0.025329 |
| DDX46 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 | -0.0251983 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | -0.0251944 |
| CERT1 | ceramide transporter 1 | -0.024798 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0246104 |
| OXSR1 | oxidative stress responsive 1 | -0.0244691 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | -0.0239814 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | -0.0238899 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0237607 |
| POTEF | POTE ankyrin domain family, member F | -0.0236832 |
| HJURP | Holliday junction recognition protein | -0.0236285 |
| CUX1 | cut-like homeobox 1 | -0.0235724 |
| FOXP1 | forkhead box P1 | -0.0234595 |
| RNF213 | ring finger protein 213 | -0.0233852 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | -0.0233597 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0232429 |
| RPS17 | ribosomal protein S17 | -0.0230604 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0228614 |
| GOSR2 | golgi SNAP receptor complex member 2 | -0.0228038 |
| COLEC11 | collectin sub-family member 11 | -0.0227742 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -0.0223197 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0223178 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0221969 |
| FMNL2 | formin-like 2 | -0.0220736 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0220226 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0217678 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0217455 |
| ATF6 | activating transcription factor 6 | -0.0216234 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | -0.0216112 |
| SCAPER | S-phase cyclin A-associated protein in the ER | -0.0215319 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | -0.0214938 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | -0.0214863 |
| IL6ST | interleukin 6 signal transducer | -0.0214666 |
| FTL | ferritin, light polypeptide | -0.0213591 |
| ZNF609 | zinc finger protein 609 | -0.021163 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0211169 |
| PRR16 | proline rich 16 | -0.0210581 |
| MSANTD3 | Myb/SANT-like DNA-binding domain containing 3 | -0.0210361 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0210249 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0210013 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0207094 |
