| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ixazomib citrate perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ixazomib citrate_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SQSTM1 | sequestosome 1 | 0.165088 |
| MAP1B | microtubule-associated protein 1B | 0.136902 |
| ASPH | aspartate beta-hydroxylase | 0.0903981 |
| TUSC3 | tumor suppressor candidate 3 | 0.0576546 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0570184 |
| DLGAP3 | discs, large (Drosophila) homolog-associated protein 3 | 0.0503248 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.049279 |
| EREG | epiregulin | 0.0471221 |
| UBC | ubiquitin C | 0.0470332 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0462272 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.045833 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0427415 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.0410112 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0388559 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0385689 |
| SFTPA2 | surfactant protein A2 | 0.0358265 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0348257 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0342667 |
| DST | dystonin | 0.0326205 |
| FTL | ferritin, light polypeptide | 0.0325907 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0316269 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0315305 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0309771 |
| FAM219A | family with sequence similarity 219, member A | 0.0300717 |
| TXNRD1 | thioredoxin reductase 1 | 0.0298283 |
| TPM3 | tropomyosin 3 | 0.0296898 |
| PSMD1 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 | 0.0287562 |
| MSN | moesin | 0.0281835 |
| UBXN4 | UBX domain protein 4 | 0.0270227 |
| VMP1 | vacuole membrane protein 1 | 0.0268833 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.026532 |
| NIBAN1 | niban apoptosis regulator 1 | 0.0262036 |
| SNX29 | sorting nexin 29 | 0.025825 |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) | 0.0256265 |
| NCKAP1 | NCK-associated protein 1 | 0.0250412 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0249761 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.024805 |
| UBR3 | ubiquitin protein ligase E3 component n-recognin 3 (putative) | 0.0241921 |
| DYNC1I1 | dynein, cytoplasmic 1, intermediate chain 1 | 0.0235048 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.023157 |
| KIF1B | kinesin family member 1B | 0.0227188 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0224573 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0222903 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0222598 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0215632 |
| SMAD3 | SMAD family member 3 | 0.0214339 |
| SLMAP | sarcolemma associated protein | 0.0213471 |
| FOSL1 | FOS-like antigen 1 | 0.0210872 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0209498 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0207177 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0205573 |
| RTN4 | reticulon 4 | 0.020343 |
| ECPAS | Ecm29 proteasome adaptor and scaffold | 0.0200093 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0198466 |
| CORO1C | coronin, actin binding protein, 1C | 0.0197962 |
| SEPTIN9 | septin 9 | 0.0196112 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0193238 |
| TTC1 | tetratricopeptide repeat domain 1 | 0.0185815 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0182727 |
| KIAA1217 | KIAA1217 | 0.0181085 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0180933 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0180805 |
| CENPF | centromere protein F, 350/400kDa | 0.0180433 |
| SEL1L3 | sel-1 suppressor of lin-12-like 3 (C. elegans) | 0.0178449 |
| MKI67 | marker of proliferation Ki-67 | 0.0175587 |
| KLC1 | kinesin light chain 1 | 0.0173551 |
| BUB3 | BUB3 mitotic checkpoint protein | 0.0172748 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0170674 |
| UBE2K | ubiquitin-conjugating enzyme E2K | 0.017056 |
| VCP | valosin containing protein | 0.0170534 |
| FAT1 | FAT atypical cadherin 1 | 0.0168737 |
| PSMD11 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 | 0.0167802 |
| TAPBP | TAP binding protein (tapasin) | 0.0163559 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | 0.0163277 |
| EXOC6B | exocyst complex component 6B | 0.0163007 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0161727 |
| NPLOC4 | nuclear protein localization 4 homolog (S. cerevisiae) | 0.0157719 |
| ANXA5 | annexin A5 | 0.0155409 |
| SLC38A6 | solute carrier family 38, member 6 | 0.0154367 |
| KCMF1 | potassium channel modulatory factor 1 | 0.0149647 |
| UBQLN1 | ubiquilin 1 | 0.0149421 |
| BUB1 | BUB1 mitotic checkpoint serine/threonine kinase | 0.0147146 |
| NAA25 | N(alpha)-acetyltransferase 25, NatB auxiliary subunit | 0.0147055 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | 0.0146946 |
| BRD4 | bromodomain containing 4 | 0.0146479 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.0145961 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0142833 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | 0.0142653 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0141957 |
| SMG7 | SMG7 nonsense mediated mRNA decay factor | 0.0141536 |
| CEP290 | centrosomal protein 290kDa | 0.0141229 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.014029 |
| MGST1 | microsomal glutathione S-transferase 1 | 0.0139912 |
| AREG | amphiregulin | 0.0139657 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0139202 |
| SNX9 | sorting nexin 9 | 0.0137443 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | 0.0137373 |
| DDIT3 | DNA-damage-inducible transcript 3 | 0.0137149 |
| PLAA | phospholipase A2-activating protein | 0.0136813 |
| GPATCH2 | G patch domain containing 2 | 0.0136661 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.302903 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.268482 |
| NRG1 | neuregulin 1 | -0.196261 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.157025 |
| PTMA | prothymosin, alpha | -0.116279 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.107391 |
| HMGA2 | high mobility group AT-hook 2 | -0.103329 |
| TMSB10 | thymosin beta 10 | -0.10106 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.100384 |
| ITGA1 | integrin, alpha 1 | -0.0995691 |
| HLA-B | major histocompatibility complex, class I, B | -0.0831761 |
| GLIS3 | GLIS family zinc finger 3 | -0.0828576 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0808017 |
| EFNA5 | ephrin-A5 | -0.0744814 |
| S100A6 | S100 calcium binding protein A6 | -0.0739827 |
| TXNIP | thioredoxin interacting protein | -0.0685121 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0618848 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0602649 |
| VIM | vimentin | -0.0589377 |
| SYT1 | synaptotagmin I | -0.052798 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0512448 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0507074 |
| HIPK2 | homeodomain interacting protein kinase 2 | -0.0486375 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0471167 |
| AHR | aryl hydrocarbon receptor | -0.0470509 |
| RAI14 | retinoic acid induced 14 | -0.0466828 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0459023 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0444161 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0442955 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0437119 |
| LMNA | lamin A/C | -0.0434413 |
| ETV1 | ets variant 1 | -0.0433696 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.042821 |
| PKM | pyruvate kinase, muscle | -0.0413799 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0409792 |
| NRP1 | neuropilin 1 | -0.0408395 |
| TMSB4X | thymosin beta 4, X-linked | -0.0384569 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0383273 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.037807 |
| TNS3 | tensin 3 | -0.0374504 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0371425 |
| RPS24 | ribosomal protein S24 | -0.0361906 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0358178 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0355515 |
| GNAS | GNAS complex locus | -0.0355029 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0354873 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0353097 |
| RPLP1 | ribosomal protein, large, P1 | -0.0347559 |
| ETV6 | ets variant 6 | -0.0339409 |
| RPL35A | ribosomal protein L35a | -0.0337091 |
| TMEM165 | transmembrane protein 165 | -0.0335727 |
| B2M | beta-2-microglobulin | -0.0334049 |
| RPL31 | ribosomal protein L31 | -0.0331004 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0327647 |
| CANX | calnexin | -0.0326924 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0326068 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0325221 |
| RPS6 | ribosomal protein S6 | -0.0325077 |
| USP34 | ubiquitin specific peptidase 34 | -0.032206 |
| MT2A | metallothionein 2A | -0.0315847 |
| RUNX2 | runt-related transcription factor 2 | -0.031384 |
| AHRR | aryl-hydrocarbon receptor repressor | -0.0310614 |
| HMGA1 | high mobility group AT-hook 1 | -0.0309164 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0308604 |
| RPS25 | ribosomal protein S25 | -0.0307877 |
| RPL9 | ribosomal protein L9 | -0.0307054 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0299979 |
| RPL34 | ribosomal protein L34 | -0.0298238 |
| CALU | calumenin | -0.0295384 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0294956 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.0293127 |
| TPR | translocated promoter region, nuclear basket protein | -0.0289785 |
| AHI1 | Abelson helper integration site 1 | -0.0289648 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0287954 |
| PLIN2 | perilipin 2 | -0.0287217 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0286817 |
| FOXP1 | forkhead box P1 | -0.0282763 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0281455 |
| NDRG1 | N-myc downstream regulated 1 | -0.0276979 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.0276751 |
| HMGB3 | high mobility group box 3 | -0.0274109 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0273175 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0272282 |
| HLA-A | major histocompatibility complex, class I, A | -0.0271594 |
| S100A10 | S100 calcium binding protein A10 | -0.027131 |
| RPL28 | ribosomal protein L28 | -0.0270844 |
| TMEM156 | transmembrane protein 156 | -0.0270705 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0270665 |
| RRBP1 | ribosome binding protein 1 | -0.0270655 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0267225 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0266167 |
| NCOA7 | nuclear receptor coactivator 7 | -0.026452 |
| RPL37A | ribosomal protein L37a | -0.0263943 |
| RPS16 | ribosomal protein S16 | -0.026031 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0260099 |
| MAP4K3 | mitogen-activated protein kinase kinase kinase kinase 3 | -0.0259066 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0256811 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0256327 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.025588 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0253754 |
