| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ixazomib citrate perturbation in SW1417 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ixazomib citrate_SW1417 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.420671 |
| FTL | ferritin, light polypeptide | 0.290297 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.168508 |
| HSPA8 | heat shock 70kDa protein 8 | 0.14893 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.10214 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0628751 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0569809 |
| UBC | ubiquitin C | 0.0554683 |
| HSPB1 | heat shock 27kDa protein 1 | 0.0553392 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0383674 |
| UBB | ubiquitin B | 0.0363957 |
| KRT18 | keratin 18, type I | 0.0307004 |
| CRYAB | crystallin, alpha B | 0.0301881 |
| RPL14 | ribosomal protein L14 | 0.0286395 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | 0.0261389 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0243119 |
| HSPE1 | heat shock 10kDa protein 1 | 0.0221268 |
| RPS3 | ribosomal protein S3 | 0.0220015 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0214329 |
| UBQLN1 | ubiquilin 1 | 0.0208831 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 | 0.0206974 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0204994 |
| CHORDC1 | cysteine and histidine-rich domain (CHORD) containing 1 | 0.0173215 |
| HSPA1A | heat shock 70kDa protein 1A | 0.0167749 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0165327 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0160158 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.01535 |
| CACYBP | calcyclin binding protein | 0.0151542 |
| TMA7 | translation machinery associated 7 homolog (S. cerevisiae) | 0.0150155 |
| HSPA1B | heat shock 70kDa protein 1B | 0.0147695 |
| PSMD2 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 | 0.0146854 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0146497 |
| ST13 | suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) | 0.0146072 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0142872 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0140685 |
| PSMD1 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 | 0.0140064 |
| H1-0 | H1.0 linker histone | 0.0139682 |
| ACYP2 | acylphosphatase 2, muscle type | 0.0136144 |
| TCP1 | t-complex 1 | 0.0135805 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.0130926 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0129534 |
| BAG3 | BCL2-associated athanogene 3 | 0.0123789 |
| SOD1 | superoxide dismutase 1, soluble | 0.0122524 |
| VCP | valosin containing protein | 0.012169 |
| RPS2 | ribosomal protein S2 | 0.012168 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0119958 |
| TPM3 | tropomyosin 3 | 0.0117867 |
| ANXA1 | annexin A1 | 0.0117712 |
| FKBP4 | FK506 binding protein 4, 59kDa | 0.0115116 |
| UFD1 | ubiquitin recognition factor in ER associated degradation 1 | 0.011454 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | 0.0113819 |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 | 0.011051 |
| TXNL1 | thioredoxin-like 1 | 0.0109599 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0108908 |
| SET | SET nuclear proto-oncogene | 0.0105207 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0104708 |
| PNN | pinin, desmosome associated protein | 0.0104429 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.010407 |
| TIAL1 | TIA1 cytotoxic granule-associated RNA binding protein-like 1 | 0.0102351 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 | 0.0102004 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | 0.0100204 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | 0.00989388 |
| ZFAND5 | zinc finger, AN1-type domain 5 | 0.00980867 |
| RPL18 | ribosomal protein L18 | 0.00975892 |
| TMF1 | TATA element modulatory factor 1 | 0.00969629 |
| HSPA4 | heat shock 70kDa protein 4 | 0.00964793 |
| HMGB2 | high mobility group box 2 | 0.00960613 |
| APP | amyloid beta (A4) precursor protein | 0.00959089 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.00955114 |
| DDX27 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 | 0.00951339 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | 0.00948095 |
| PSMD11 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 | 0.00907774 |
| TCEA2 | transcription elongation factor A (SII), 2 | 0.00883067 |
| CCT5 | chaperonin containing TCP1, subunit 5 (epsilon) | 0.00881325 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | 0.00877712 |
| MRPL18 | mitochondrial ribosomal protein L18 | 0.00860756 |
| ARPP19 | cAMP-regulated phosphoprotein, 19kDa | 0.00854668 |
| CNBP | CCHC-type zinc finger, nucleic acid binding protein | 0.00847744 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.00842562 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.00842417 |
| SFTPA2 | surfactant protein A2 | 0.00840427 |
| PPME1 | protein phosphatase methylesterase 1 | 0.00825092 |
| CRY1 | cryptochrome circadian clock 1 | 0.008227 |
| IFRD1 | interferon-related developmental regulator 1 | 0.00822523 |
| RUVBL2 | RuvB-like AAA ATPase 2 | 0.00810966 |
| ZFAND2A | zinc finger, AN1-type domain 2A | 0.00801848 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | 0.00797645 |
| PCYT1A | phosphate cytidylyltransferase 1, choline, alpha | 0.00795955 |
| H1-4 | H1.4 linker histone, cluster member | 0.00795336 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0079272 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.00789552 |
| PLAA | phospholipase A2-activating protein | 0.00789039 |
| SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) | 0.00788537 |
| ABHD3 | abhydrolase domain containing 3 | 0.0078745 |
| HDLBP | high density lipoprotein binding protein | 0.00785627 |
| NCKAP1 | NCK-associated protein 1 | 0.00785532 |
| S100A14 | S100 calcium binding protein A14 | 0.00782626 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.00780888 |
| CLU | clusterin | 0.00778186 |
| PSMB7 | proteasome (prosome, macropain) subunit, beta type, 7 | 0.00771618 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.102913 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0754018 |
| TMSB10 | thymosin beta 10 | -0.0643399 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.054171 |
| PTMA | prothymosin, alpha | -0.0537541 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.051266 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0502821 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.047257 |
| MACC1 | metastasis associated in colon cancer 1 | -0.0454262 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0414502 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0408481 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0385941 |
| GOLGA4 | golgin A4 | -0.0380158 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0376896 |
| TMEM123 | transmembrane protein 123 | -0.0355791 |
| PERP | PERP, TP53 apoptosis effector | -0.0354818 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0349391 |
| JMJD1C | jumonji domain containing 1C | -0.0343455 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0326881 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0315442 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0314633 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.030797 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0307121 |
| RPLP1 | ribosomal protein, large, P1 | -0.0306683 |
| CST3 | cystatin C | -0.0293907 |
| NEBL | nebulette | -0.0284377 |
| BCL2L1 | BCL2-like 1 | -0.0283578 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0280006 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0272431 |
| ACTN4 | actinin, alpha 4 | -0.0269456 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0264256 |
| ADNP | activity-dependent neuroprotector homeobox | -0.0262612 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0260078 |
| EGR1 | early growth response 1 | -0.0259241 |
| WWC1 | WW and C2 domain containing 1 | -0.0255701 |
| GNAS | GNAS complex locus | -0.0247426 |
| HM13 | histocompatibility (minor) 13 | -0.0247007 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0242427 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0242413 |
| COG5 | component of oligomeric golgi complex 5 | -0.0241234 |
| FOSL1 | FOS-like antigen 1 | -0.024046 |
| MED13L | mediator complex subunit 13-like | -0.0240324 |
| YAP1 | Yes-associated protein 1 | -0.0239697 |
| CTDSPL | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like | -0.0239148 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0236795 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0230497 |
| ERBIN | erbb2 interacting protein | -0.0229336 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0227465 |
| MYOF | myoferlin | -0.0227117 |
| PRELID2 | PRELI domain containing 2 | -0.0227112 |
| PKP4 | plakophilin 4 | -0.0226309 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | -0.022421 |
| NF1 | neurofibromin 1 | -0.0223925 |
| RNF43 | ring finger protein 43 | -0.022058 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0217029 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0216725 |
| B2M | beta-2-microglobulin | -0.0216247 |
| HMGA1 | high mobility group AT-hook 1 | -0.0214901 |
| PKM | pyruvate kinase, muscle | -0.0214118 |
| FAT1 | FAT atypical cadherin 1 | -0.0213049 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0213 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0211692 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0211603 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0210898 |
| NDRG1 | N-myc downstream regulated 1 | -0.0210828 |
| CCND1 | cyclin D1 | -0.0210166 |
| SETD5 | SET domain containing 5 | -0.0207312 |
| BBX | bobby sox homolog (Drosophila) | -0.0205706 |
| CALU | calumenin | -0.0204672 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.0204425 |
| XPO1 | exportin 1 | -0.0203614 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0202577 |
| RUNX1 | runt-related transcription factor 1 | -0.0201185 |
| USP34 | ubiquitin specific peptidase 34 | -0.020105 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0197279 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0197145 |
| TXNIP | thioredoxin interacting protein | -0.0197005 |
| CD46 | CD46 molecule, complement regulatory protein | -0.0193857 |
| NFIA | nuclear factor I/A | -0.0192432 |
| PCLO | piccolo presynaptic cytomatrix protein | -0.0192266 |
| SERINC5 | serine incorporator 5 | -0.019221 |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 | -0.0192051 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | -0.0191973 |
| CLDN4 | claudin 4 | -0.0191102 |
| RPS24 | ribosomal protein S24 | -0.0191039 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0190011 |
| NHSL1 | NHS-like 1 | -0.0189955 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0189383 |
| RPLP2 | ribosomal protein, large, P2 | -0.0189029 |
| PTK2 | protein tyrosine kinase 2 | -0.0188993 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0188121 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0187849 |
| SNX9 | sorting nexin 9 | -0.0186701 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.018631 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0185667 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0185278 |
| PTEN | phosphatase and tensin homolog | -0.0185059 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.018423 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0183212 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0180532 |
