| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ixazomib citrate perturbation in SW48 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ixazomib citrate_SW48 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA8 | heat shock 70kDa protein 8 | 0.0553419 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0363126 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0313382 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0308309 |
| RPL3 | ribosomal protein L3 | 0.0296638 |
| RPS2 | ribosomal protein S2 | 0.0269024 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0259607 |
| NUP58 | nucleoporin 58 | 0.025431 |
| NCKAP1 | NCK-associated protein 1 | 0.0251863 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0240109 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0219901 |
| MYO5B | myosin VB | 0.0217433 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.020975 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0209006 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0206804 |
| COPA | coatomer protein complex, subunit alpha | 0.0202586 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0197907 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0196422 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0188485 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0184724 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 0.0182991 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0178052 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.0176544 |
| HDGF | hepatoma-derived growth factor | 0.017648 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0170592 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0169929 |
| CTSB | cathepsin B | 0.0167723 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0165507 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0163851 |
| USP53 | ubiquitin specific peptidase 53 | 0.0161049 |
| BRD2 | bromodomain containing 2 | 0.0157296 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0156732 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0156365 |
| SPAG9 | sperm associated antigen 9 | 0.0155756 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0155101 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.0149271 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | 0.0149192 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0148492 |
| PSAT1 | phosphoserine aminotransferase 1 | 0.0147683 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0144783 |
| USP24 | ubiquitin specific peptidase 24 | 0.0139719 |
| TAPBP | TAP binding protein (tapasin) | 0.0139659 |
| FAR1 | fatty acyl CoA reductase 1 | 0.0137315 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0136393 |
| JMY | junction mediating and regulatory protein, p53 cofactor | 0.0133407 |
| PSMD11 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 | 0.013302 |
| PNN | pinin, desmosome associated protein | 0.0133001 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0131993 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0131426 |
| CCNL1 | cyclin L1 | 0.0130559 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0129774 |
| RPS3 | ribosomal protein S3 | 0.0128796 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.0127875 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.012695 |
| TPM3 | tropomyosin 3 | 0.012619 |
| FAM120A | family with sequence similarity 120A | 0.0124814 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0124244 |
| ZFP36 | ZFP36 ring finger protein | 0.0123619 |
| DSCAM | Down syndrome cell adhesion molecule | 0.012263 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0122535 |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 | 0.0122041 |
| UBC | ubiquitin C | 0.0120704 |
| HELZ | helicase with zinc finger | 0.012022 |
| IRS2 | insulin receptor substrate 2 | 0.0118699 |
| ECPAS | Ecm29 proteasome adaptor and scaffold | 0.0118666 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0118415 |
| SETD5 | SET domain containing 5 | 0.0118223 |
| RNF145 | ring finger protein 145 | 0.0118062 |
| RPS3A | ribosomal protein S3A | 0.0117586 |
| DIAPH1 | diaphanous-related formin 1 | 0.0116285 |
| NDRG1 | N-myc downstream regulated 1 | 0.0116197 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0115579 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | 0.0114738 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0113745 |
| MIDEAS | mitotic deacetylase associated SANT domain protein | 0.0113415 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0112971 |
| RANBP2 | RAN binding protein 2 | 0.0112834 |
| ARRDC3 | arrestin domain containing 3 | 0.0111381 |
| USP3 | ubiquitin specific peptidase 3 | 0.0110494 |
| CPOX | coproporphyrinogen oxidase | 0.01104 |
| TMF1 | TATA element modulatory factor 1 | 0.0110201 |
| VEGFA | vascular endothelial growth factor A | 0.0110148 |
| TMA7 | translation machinery associated 7 homolog (S. cerevisiae) | 0.0109783 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0109778 |
| ATF3 | activating transcription factor 3 | 0.0108495 |
| NOS1AP | nitric oxide synthase 1 (neuronal) adaptor protein | 0.0108394 |
| SFTPA2 | surfactant protein A2 | 0.0108179 |
| MKRN1 | makorin ring finger protein 1 | 0.0107672 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | 0.0106631 |
| BRD4 | bromodomain containing 4 | 0.0106134 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0105941 |
| RBM39 | RNA binding motif protein 39 | 0.0105321 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.0105305 |
| YTHDC1 | YTH domain containing 1 | 0.0105188 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0105109 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0105082 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | 0.0105057 |
| SET | SET nuclear proto-oncogene | 0.0104889 |
| EWSR1 | EWS RNA-binding protein 1 | 0.0104826 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0104317 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CD36 | CD36 molecule (thrombospondin receptor) | -0.192993 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.185287 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.163188 |
| HMGA2 | high mobility group AT-hook 2 | -0.123285 |
| RAD51B | RAD51 paralog B | -0.120857 |
| FERMT1 | fermitin family member 1 | -0.106857 |
| FHIT | fragile histidine triad | -0.0911981 |
| OXR1 | oxidation resistance 1 | -0.0810454 |
| TMSB10 | thymosin beta 10 | -0.0796434 |
| RPS24 | ribosomal protein S24 | -0.0756268 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0734906 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0716918 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0715672 |
| EGFR | epidermal growth factor receptor | -0.0668787 |
| MTAP | methylthioadenosine phosphorylase | -0.0617132 |
| CD9 | CD9 molecule | -0.0605328 |
| SERINC5 | serine incorporator 5 | -0.0577671 |
| LAMB3 | laminin, beta 3 | -0.0572281 |
| FRAS1 | Fraser extracellular matrix complex subunit 1 | -0.056956 |
| HDAC2 | histone deacetylase 2 | -0.0547016 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0537412 |
| RBM25 | RNA binding motif protein 25 | -0.0534048 |
| RPLP1 | ribosomal protein, large, P1 | -0.0522809 |
| VCL | vinculin | -0.0512706 |
| LRP8 | low density lipoprotein receptor-related protein 8, apolipoprotein e receptor | -0.0511934 |
| GPHN | gephyrin | -0.0508995 |
| EXOC4 | exocyst complex component 4 | -0.0507933 |
| SMYD3 | SET and MYND domain containing 3 | -0.050307 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0497563 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.0495752 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0493099 |
| CUX1 | cut-like homeobox 1 | -0.0485826 |
| LMO7 | LIM domain 7 | -0.048575 |
| PHF14 | PHD finger protein 14 | -0.0470297 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0457688 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0455214 |
| EHBP1 | EH domain binding protein 1 | -0.0452645 |
| AOPEP | aminopeptidase O (putative) | -0.0448756 |
| PTMA | prothymosin, alpha | -0.0447048 |
| IER3 | immediate early response 3 | -0.0444861 |
| EMP1 | epithelial membrane protein 1 | -0.0441761 |
| ANXA2 | annexin A2 | -0.0436996 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.0407694 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0405271 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0399941 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0399897 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) | -0.0393633 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0389417 |
| RPL32 | ribosomal protein L32 | -0.0383605 |
| ITPKC | inositol-trisphosphate 3-kinase C | -0.0375947 |
| PATJ | PATJ crumbs cell polarity complex component | -0.037402 |
| CTDSPL | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like | -0.036712 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0364159 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0363895 |
| PERP | PERP, TP53 apoptosis effector | -0.035625 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0355743 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0355489 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | -0.0349334 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0346457 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | -0.0342414 |
| RPS19 | ribosomal protein S19 | -0.0339639 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.033441 |
| RPL23 | ribosomal protein L23 | -0.033368 |
| SKAP1 | src kinase associated phosphoprotein 1 | -0.0332826 |
| S100A10 | S100 calcium binding protein A10 | -0.0325708 |
| TPM4 | tropomyosin 4 | -0.0323317 |
| CDK13 | cyclin-dependent kinase 13 | -0.0321657 |
| RPL12 | ribosomal protein L12 | -0.0320575 |
| JMJD1C | jumonji domain containing 1C | -0.0317304 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0317173 |
| CCND1 | cyclin D1 | -0.0309374 |
| MT2A | metallothionein 2A | -0.0308052 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 | -0.0305027 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0302381 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0296543 |
| ADGRA3 | adhesion G protein-coupled receptor A3 | -0.0294387 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0291617 |
| ATXN1 | ataxin 1 | -0.0290511 |
| USP34 | ubiquitin specific peptidase 34 | -0.0289622 |
| FLOT1 | flotillin 1 | -0.0287344 |
| LAMC2 | laminin, gamma 2 | -0.0285355 |
| DIAPH2 | diaphanous-related formin 2 | -0.0283495 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0278741 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0278091 |
| TENM3 | teneurin transmembrane protein 3 | -0.0277756 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0277594 |
| LAMA4 | laminin, alpha 4 | -0.0277458 |
| ACTN4 | actinin, alpha 4 | -0.0274386 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -0.0274361 |
| TCF12 | transcription factor 12 | -0.0274359 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0273814 |
| KRT18 | keratin 18, type I | -0.0271203 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0269269 |
| ACTG1 | actin gamma 1 | -0.0268814 |
| DEK | DEK proto-oncogene | -0.0265691 |
| PARD3B | par-3 family cell polarity regulator beta | -0.0262363 |
| ZBTB7C | zinc finger and BTB domain containing 7C | -0.026231 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | -0.0256575 |
| RPS4X | ribosomal protein S4, X-linked | -0.0250994 |
| DENND1A | DENN/MADD domain containing 1A | -0.0250115 |
