| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ixazomib citrate perturbation in SW480 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ixazomib citrate_SW480 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.283005 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.121828 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.101545 |
| RPS3 | ribosomal protein S3 | 0.0818375 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.076769 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0658846 |
| EZR | ezrin | 0.0610112 |
| KIZ | kizuna centrosomal protein | 0.0591697 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.05827 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0581994 |
| MSN | moesin | 0.0553698 |
| DST | dystonin | 0.055229 |
| VCL | vinculin | 0.054462 |
| ITGA6 | integrin, alpha 6 | 0.0544132 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0542973 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0535673 |
| BCL2L1 | BCL2-like 1 | 0.0527382 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.052075 |
| VMP1 | vacuole membrane protein 1 | 0.0511855 |
| ASPH | aspartate beta-hydroxylase | 0.0456751 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0449686 |
| LMO7 | LIM domain 7 | 0.0433223 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0428453 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0426434 |
| KRT5 | keratin 5, type II | 0.0380516 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0380329 |
| SEPTIN9 | septin 9 | 0.0372831 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0371818 |
| LAMA4 | laminin, alpha 4 | 0.0364366 |
| CTSB | cathepsin B | 0.0352554 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0346543 |
| FLNB | filamin B, beta | 0.0335433 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0334463 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0332037 |
| JAG1 | jagged 1 | 0.0331887 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0324031 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0320695 |
| TMF1 | TATA element modulatory factor 1 | 0.0319484 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0317973 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0315121 |
| SMAD3 | SMAD family member 3 | 0.0312028 |
| ACTN4 | actinin, alpha 4 | 0.0309025 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0301924 |
| LDHA | lactate dehydrogenase A | 0.0297917 |
| SFTPA2 | surfactant protein A2 | 0.0289338 |
| DSPP | dentin sialophosphoprotein | 0.0289278 |
| MAP1B | microtubule-associated protein 1B | 0.0288736 |
| RPL14 | ribosomal protein L14 | 0.0286288 |
| SPATA13 | spermatogenesis associated 13 | 0.027647 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0272765 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0270333 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0269582 |
| MYOF | myoferlin | 0.0266003 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0265944 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0262529 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0255459 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0252343 |
| HADHA | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit | 0.0252205 |
| MT2A | metallothionein 2A | 0.0250427 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.025029 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0249197 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0248077 |
| SET | SET nuclear proto-oncogene | 0.0246802 |
| ZNF146 | zinc finger protein 146 | 0.0246741 |
| CNBP | CCHC-type zinc finger, nucleic acid binding protein | 0.0246466 |
| PNN | pinin, desmosome associated protein | 0.0237117 |
| ANO6 | anoctamin 6 | 0.0235462 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0234481 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0233768 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0231739 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.023099 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0230853 |
| RPS2 | ribosomal protein S2 | 0.0230161 |
| TPM3 | tropomyosin 3 | 0.0229953 |
| SLC1A5 | solute carrier family 1 (neutral amino acid transporter), member 5 | 0.0226818 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0226645 |
| NEBL | nebulette | 0.0226178 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0225229 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0224221 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0222931 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 0.0222423 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0221969 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0221711 |
| BRD2 | bromodomain containing 2 | 0.0221156 |
| SLC38A1 | solute carrier family 38, member 1 | 0.0219248 |
| NUDT4 | nudix (nucleoside diphosphate linked moiety X)-type motif 4 | 0.0218571 |
| PLEC | plectin | 0.0218348 |
| TGM2 | transglutaminase 2 | 0.0217469 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | 0.0216237 |
| CORO1C | coronin, actin binding protein, 1C | 0.0215101 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0213547 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.021277 |
| UBXN4 | UBX domain protein 4 | 0.0207296 |
| VCP | valosin containing protein | 0.0207115 |
| DUSP6 | dual specificity phosphatase 6 | 0.0206455 |
| ZNF638 | zinc finger protein 638 | 0.0204143 |
| EFNB2 | ephrin-B2 | 0.0201591 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | 0.0200656 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0199665 |
| GOLGB1 | golgin B1 | 0.019868 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.130545 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.107013 |
| RPS24 | ribosomal protein S24 | -0.0782054 |
| HMGA1 | high mobility group AT-hook 1 | -0.0763835 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0738174 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0700817 |
| RPLP1 | ribosomal protein, large, P1 | -0.0617931 |
| RPL35A | ribosomal protein L35a | -0.0615542 |
| TMSB10 | thymosin beta 10 | -0.0584844 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0581697 |
| PTMA | prothymosin, alpha | -0.0576035 |
| WWOX | WW domain containing oxidoreductase | -0.0523399 |
| RPL23 | ribosomal protein L23 | -0.0498529 |
| TMEM123 | transmembrane protein 123 | -0.0486229 |
| CDH13 | cadherin 13 | -0.0485315 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0471804 |
| HMGB1 | high mobility group box 1 | -0.0454147 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0432327 |
| NAV2 | neuron navigator 2 | -0.0415633 |
| SYT1 | synaptotagmin I | -0.0411885 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | -0.0406417 |
| PERP | PERP, TP53 apoptosis effector | -0.0406291 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0398328 |
| DIAPH3 | diaphanous-related formin 3 | -0.0394881 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0382206 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0371302 |
| RUNX1 | runt-related transcription factor 1 | -0.0360648 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0350888 |
| ZNF292 | zinc finger protein 292 | -0.0340386 |
| RPLP0 | ribosomal protein, large, P0 | -0.0335423 |
| CDK8 | cyclin-dependent kinase 8 | -0.0333593 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.0329232 |
| ZNRF3 | zinc and ring finger 3 | -0.0327781 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0326433 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0323853 |
| SKAP1 | src kinase associated phosphoprotein 1 | -0.0318049 |
| COG5 | component of oligomeric golgi complex 5 | -0.0315671 |
| GNAS | GNAS complex locus | -0.0314633 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0311633 |
| RPS25 | ribosomal protein S25 | -0.0310663 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0310246 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0308884 |
| NF1 | neurofibromin 1 | -0.0300521 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | -0.0299136 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | -0.02968 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0296546 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0290383 |
| ETNK1 | ethanolamine kinase 1 | -0.0289059 |
| TUBA1B | tubulin, alpha 1b | -0.028772 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0283923 |
| ZNF207 | zinc finger protein 207 | -0.0276386 |
| PKM | pyruvate kinase, muscle | -0.0274705 |
| S100A10 | S100 calcium binding protein A10 | -0.0274252 |
| RPL36A | ribosomal protein L36a | -0.0271483 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0270291 |
| VOPP1 | vesicular, overexpressed in cancer, prosurvival protein 1 | -0.0267062 |
| DEK | DEK proto-oncogene | -0.026663 |
| CBFB | core-binding factor, beta subunit | -0.0266439 |
| HS3ST5 | heparan sulfate (glucosamine) 3-O-sulfotransferase 5 | -0.0263466 |
| TUBB | tubulin, beta class I | -0.026225 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0257417 |
| RPLP2 | ribosomal protein, large, P2 | -0.0256834 |
| OXR1 | oxidation resistance 1 | -0.0255506 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.025286 |
| SMYD3 | SET and MYND domain containing 3 | -0.0250638 |
| ACTG1 | actin gamma 1 | -0.0246925 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0245132 |
| USP34 | ubiquitin specific peptidase 34 | -0.0244201 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | -0.0243751 |
| RBM39 | RNA binding motif protein 39 | -0.0243285 |
| RPL28 | ribosomal protein L28 | -0.0243229 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0242112 |
| UBE2V1 | ubiquitin-conjugating enzyme E2 variant 1 | -0.0241783 |
| TRA2B | transformer 2 beta homolog (Drosophila) | -0.0240027 |
| ATXN1 | ataxin 1 | -0.0239194 |
| RPS5 | ribosomal protein S5 | -0.0236192 |
| MATR3 | matrin 3 | -0.0235104 |
| RPL12 | ribosomal protein L12 | -0.0233548 |
| RPS15 | ribosomal protein S15 | -0.0231756 |
| ARHGAP12 | Rho GTPase activating protein 12 | -0.0228829 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0227147 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.022651 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0225578 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0222307 |
| OSBPL3 | oxysterol binding protein-like 3 | -0.0219446 |
| AK1 | adenylate kinase 1 | -0.0219252 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.021904 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | -0.021874 |
| OLA1 | Obg-like ATPase 1 | -0.0218548 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0217299 |
| RPS19 | ribosomal protein S19 | -0.0216111 |
| RPL35 | ribosomal protein L35 | -0.0215752 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0210582 |
| RPL27A | ribosomal protein L27a | -0.0208035 |
| PCDH9 | protocadherin 9 | -0.0205607 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0203076 |
| RAB22A | RAB22A, member RAS oncogene family | -0.0202592 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | -0.0202193 |
| GORASP2 | golgi reassembly stacking protein 2, 55kDa | -0.0202002 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0201109 |
