| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ixazomib perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ixazomib_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VCL | vinculin | 0.178112 |
| TLE4 | transducin-like enhancer of split 4 | 0.0807683 |
| FMN1 | formin 1 | 0.0805779 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0628266 |
| TPM1 | tropomyosin 1 (alpha) | 0.0470844 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.036183 |
| EXT1 | exostosin glycosyltransferase 1 | 0.035864 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.035852 |
| STK38L | serine/threonine kinase 38 like | 0.0340627 |
| MYO1E | myosin IE | 0.0332469 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0329039 |
| FERMT2 | fermitin family member 2 | 0.0322298 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0313616 |
| GLCCI1 | glucocorticoid induced 1 | 0.0305545 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0304279 |
| INTS6 | integrator complex subunit 6 | 0.0300036 |
| PCBP2 | poly(rC) binding protein 2 | 0.0290709 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0286652 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0282156 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0279302 |
| BPTF | bromodomain PHD finger transcription factor | 0.027918 |
| VEGFA | vascular endothelial growth factor A | 0.0270737 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0269219 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0260335 |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 | 0.025774 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0257504 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0256683 |
| VMP1 | vacuole membrane protein 1 | 0.024989 |
| LSAMP | limbic system-associated membrane protein | 0.0248113 |
| AUTS2 | autism susceptibility candidate 2 | 0.0242344 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0235091 |
| HOMER1 | homer scaffolding protein 1 | 0.0231764 |
| RNF213 | ring finger protein 213 | 0.0229694 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | 0.0227255 |
| AEBP2 | AE binding protein 2 | 0.0226904 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0226014 |
| DGKH | diacylglycerol kinase, eta | 0.0223491 |
| UNC5C | unc-5 homolog C (C. elegans) | 0.0216443 |
| DPH6 | diphthamine biosynthesis 6 | 0.0214844 |
| TENM4 | teneurin transmembrane protein 4 | 0.0213668 |
| SYNPO2 | synaptopodin 2 | 0.0212912 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0211762 |
| TRIB2 | tribbles pseudokinase 2 | 0.0210668 |
| DST | dystonin | 0.0209954 |
| SIK2 | salt-inducible kinase 2 | 0.0207171 |
| MCL1 | myeloid cell leukemia 1 | 0.0205487 |
| FLT1 | fms-related tyrosine kinase 1 | 0.0203254 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0202369 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.0200238 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | 0.019854 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0198293 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0197853 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0197261 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0196611 |
| UBAP2 | ubiquitin associated protein 2 | 0.0195818 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.019497 |
| BAZ2B | bromodomain adjacent to zinc finger domain, 2B | 0.0192687 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0187571 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0182916 |
| LIMA1 | LIM domain and actin binding 1 | 0.0180694 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0180685 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0179707 |
| GREM2 | gremlin 2, DAN family BMP antagonist | 0.0177229 |
| TPST1 | tyrosylprotein sulfotransferase 1 | 0.0177022 |
| RNF150 | ring finger protein 150 | 0.0176057 |
| COL4A2 | collagen, type IV, alpha 2 | 0.0174573 |
| CYTH1 | cytohesin 1 | 0.0173515 |
| MYCN | v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog | 0.0171869 |
| FHL2 | four and a half LIM domains 2 | 0.0171594 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | 0.017112 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0170935 |
| SLITRK6 | SLIT and NTRK-like family, member 6 | 0.0170395 |
| ANKS1A | ankyrin repeat and sterile alpha motif domain containing 1A | 0.0169659 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0168929 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0168035 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.0164239 |
| SEPTIN9 | septin 9 | 0.0163181 |
| SYT1 | synaptotagmin I | 0.0161889 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0160558 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0159123 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.0157051 |
| SETBP1 | SET binding protein 1 | 0.0155461 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | 0.0154531 |
| MAPK10 | mitogen-activated protein kinase 10 | 0.0153639 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | 0.0151966 |
| ITGA1 | integrin, alpha 1 | 0.0150954 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0149293 |
| EXOC4 | exocyst complex component 4 | 0.0146196 |
| WDR1 | WD repeat domain 1 | 0.0146064 |
| STXBP4 | syntaxin binding protein 4 | 0.014534 |
| MBTD1 | mbt domain containing 1 | 0.0145293 |
| PTPRE | protein tyrosine phosphatase, receptor type, E | 0.0144771 |
| RCOR1 | REST corepressor 1 | 0.0144599 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.0143177 |
| ACTN1 | actinin, alpha 1 | 0.013951 |
| PLPP1 | phospholipid phosphatase 1 | 0.0138315 |
| ZNF638 | zinc finger protein 638 | 0.0137837 |
| DACH2 | dachshund family transcription factor 2 | 0.0135118 |
| PDE10A | phosphodiesterase 10A | 0.013479 |
| COL4A1 | collagen, type IV, alpha 1 | 0.0134419 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | -0.232639 |
| IGF2 | insulin-like growth factor 2 | -0.224724 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.20785 |
| PTMA | prothymosin, alpha | -0.124323 |
| VIM | vimentin | -0.0974633 |
| COL1A1 | collagen, type I, alpha 1 | -0.0893485 |
| RPL23 | ribosomal protein L23 | -0.0775701 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0602254 |
| RPL19 | ribosomal protein L19 | -0.055977 |
| COL3A1 | collagen, type III, alpha 1 | -0.0551144 |
| RPS24 | ribosomal protein S24 | -0.0539364 |
| TMSB10 | thymosin beta 10 | -0.0535329 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.052697 |
| RPS6 | ribosomal protein S6 | -0.051271 |
| RPL35A | ribosomal protein L35a | -0.0449658 |
| RPL34 | ribosomal protein L34 | -0.0442949 |
| RPL38 | ribosomal protein L38 | -0.0405517 |
| RPLP1 | ribosomal protein, large, P1 | -0.0397248 |
| RPS27A | ribosomal protein S27a | -0.0381565 |
| MAP1B | microtubule-associated protein 1B | -0.0344593 |
| RPL26 | ribosomal protein L26 | -0.034426 |
| B2M | beta-2-microglobulin | -0.0334713 |
| H3-3B | H3.3 histone B | -0.033153 |
| S100A9 | S100 calcium binding protein A9 | -0.0327158 |
| ACTG1 | actin gamma 1 | -0.032626 |
| RPL37A | ribosomal protein L37a | -0.031394 |
| RPL32 | ribosomal protein L32 | -0.0310284 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.030249 |
| UBC | ubiquitin C | -0.029787 |
| RPS19 | ribosomal protein S19 | -0.0295903 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0295721 |
| RPL7A | ribosomal protein L7a | -0.029473 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0292195 |
| FTL | ferritin, light polypeptide | -0.0285772 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0283605 |
| GNAS | GNAS complex locus | -0.0277846 |
| AHNAK | AHNAK nucleoprotein | -0.0276117 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | -0.0275048 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0273646 |
| ZNF292 | zinc finger protein 292 | -0.0256896 |
| ENO1 | enolase 1, (alpha) | -0.0254667 |
| SCG2 | secretogranin II | -0.0251252 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0247113 |
| POTEF | POTE ankyrin domain family, member F | -0.0245018 |
| RPL9 | ribosomal protein L9 | -0.0238899 |
| PKM | pyruvate kinase, muscle | -0.023108 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0225108 |
| CRH | corticotropin releasing hormone | -0.0222682 |
| HMGB2 | high mobility group box 2 | -0.0219151 |
| RPS8 | ribosomal protein S8 | -0.0215957 |
| RPS16 | ribosomal protein S16 | -0.0214364 |
| RPS25 | ribosomal protein S25 | -0.0211599 |
| CD36 | CD36 molecule (thrombospondin receptor) | -0.0208483 |
| RPLP2 | ribosomal protein, large, P2 | -0.0206038 |
| RPL12 | ribosomal protein L12 | -0.0204177 |
| CDC27 | cell division cycle 27 | -0.0202871 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0202511 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0199357 |
| S100A6 | S100 calcium binding protein A6 | -0.0196396 |
| LMNA | lamin A/C | -0.0196183 |
| WDR45B | WD repeat domain 45B | -0.019605 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0195769 |
| RPS29 | ribosomal protein S29 | -0.0195112 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0193101 |
| RPS14 | ribosomal protein S14 | -0.0191655 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.019037 |
| TBX2 | T-box 2 | -0.018743 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0182793 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0181127 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0179344 |
| RHOA | ras homolog family member A | -0.0179045 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0178846 |
| RPL31 | ribosomal protein L31 | -0.0178825 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0178165 |
| RPL36A | ribosomal protein L36a | -0.0175935 |
| RPS27 | ribosomal protein S27 | -0.0175644 |
| FNBP1 | formin binding protein 1 | -0.0174225 |
| RPS15 | ribosomal protein S15 | -0.0173826 |
| SEPTIN2 | septin 2 | -0.0173007 |
| RPL15 | ribosomal protein L15 | -0.0172007 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0171661 |
| RPS21 | ribosomal protein S21 | -0.0170812 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0170682 |
| RPS5 | ribosomal protein S5 | -0.0170211 |
| RPL36 | ribosomal protein L36 | -0.0169043 |
| RPL11 | ribosomal protein L11 | -0.0166226 |
| RPLP0 | ribosomal protein, large, P0 | -0.0163899 |
| UBE2Z | ubiquitin-conjugating enzyme E2Z | -0.0162912 |
| CALU | calumenin | -0.0162878 |
| GOLGA4 | golgin A4 | -0.0162145 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0159763 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.015763 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0156793 |
| UBE2D2 | ubiquitin-conjugating enzyme E2D 2 | -0.0156623 |
| GLG1 | golgi glycoprotein 1 | -0.0156542 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0155168 |
| PLAT | plasminogen activator, tissue | -0.015493 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | -0.0154763 |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase | -0.0153788 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0153586 |
