| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ixazomib perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ixazomib_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | 0.253649 |
| RNF213 | ring finger protein 213 | 0.130208 |
| B2M | beta-2-microglobulin | 0.114353 |
| INTS6 | integrator complex subunit 6 | 0.111554 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.105049 |
| EGR1 | early growth response 1 | 0.104561 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0927544 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0926149 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.090557 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0864399 |
| RAB7A | RAB7A, member RAS oncogene family | 0.078101 |
| EZR | ezrin | 0.0758718 |
| ANXA2 | annexin A2 | 0.0696386 |
| SMAD3 | SMAD family member 3 | 0.0690172 |
| LCN2 | lipocalin 2 | 0.0681662 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0670731 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | 0.0669283 |
| MYO1E | myosin IE | 0.0666938 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.0659323 |
| TMC5 | transmembrane channel-like 5 | 0.0651888 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0640907 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.0630865 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0624438 |
| VMP1 | vacuole membrane protein 1 | 0.0605629 |
| AREG | amphiregulin | 0.0585461 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0541238 |
| SPAG9 | sperm associated antigen 9 | 0.0533433 |
| PLSCR2 | phospholipid scramblase 2 | 0.0516207 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0510338 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | 0.0509316 |
| MCL1 | myeloid cell leukemia 1 | 0.0505583 |
| ASPH | aspartate beta-hydroxylase | 0.0504219 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0490399 |
| NDRG1 | N-myc downstream regulated 1 | 0.0484119 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.046946 |
| TJP1 | tight junction protein 1 | 0.0459682 |
| HKDC1 | hexokinase domain containing 1 | 0.0459081 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0458977 |
| STS | steroid sulfatase (microsomal), isozyme S | 0.0446451 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.044438 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.0444209 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0438798 |
| KYNU | kynureninase | 0.0435105 |
| MORF4L2 | mortality factor 4 like 2 | 0.042729 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0426503 |
| DUSP10 | dual specificity phosphatase 10 | 0.041625 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0415249 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0414291 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0412688 |
| IRF1 | interferon regulatory factor 1 | 0.0409427 |
| SIK3 | SIK family kinase 3 | 0.0407347 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0397716 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0394237 |
| VEGFA | vascular endothelial growth factor A | 0.0394045 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.0388199 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.038466 |
| RBM47 | RNA binding motif protein 47 | 0.0379233 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0378291 |
| MCU | mitochondrial calcium uniporter | 0.0375684 |
| BLZF1 | basic leucine zipper nuclear factor 1 | 0.0375555 |
| UBAP2 | ubiquitin associated protein 2 | 0.0367481 |
| RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | 0.0365829 |
| CATSPERB | catsper channel auxiliary subunit beta | 0.0364556 |
| DIAPH1 | diaphanous-related formin 1 | 0.0359298 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0357497 |
| TM4SF19 | transmembrane 4 L six family member 19 | 0.0356157 |
| UBC | ubiquitin C | 0.0353482 |
| ZNF292 | zinc finger protein 292 | 0.0342109 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0341422 |
| TRIM2 | tripartite motif containing 2 | 0.0339285 |
| ATF6 | activating transcription factor 6 | 0.0337602 |
| SP100 | SP100 nuclear antigen | 0.0334387 |
| PKM | pyruvate kinase, muscle | 0.0334171 |
| CCNL1 | cyclin L1 | 0.0327932 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.0325079 |
| ERBIN | erbb2 interacting protein | 0.032053 |
| MX1 | MX dynamin-like GTPase 1 | 0.0319581 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0316815 |
| PHACTR4 | phosphatase and actin regulator 4 | 0.0315883 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0312608 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0310657 |
| ANXA1 | annexin A1 | 0.0308992 |
| GK | glycerol kinase | 0.0308403 |
| RND3 | Rho family GTPase 3 | 0.0307308 |
| SEPTIN9 | septin 9 | 0.0306965 |
| CDHR2 | cadherin-related family member 2 | 0.0301349 |
| CALR | calreticulin | 0.0301117 |
| MT2A | metallothionein 2A | 0.029984 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0295537 |
| TMEM65 | transmembrane protein 65 | 0.0294321 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0293113 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0292923 |
| PRKCA | protein kinase C, alpha | 0.0291854 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0289223 |
| SIPA1L2 | signal-induced proliferation-associated 1 like 2 | 0.0285987 |
| TOP1 | topoisomerase (DNA) I | 0.0285528 |
| JUN | jun proto-oncogene | 0.0284535 |
| NABP1 | nucleic acid binding protein 1 | 0.0283205 |
| ZBTB43 | zinc finger and BTB domain containing 43 | 0.0282405 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0282154 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0703778 |
| RNF43 | ring finger protein 43 | -0.0637265 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0621044 |
| RUNX1 | runt-related transcription factor 1 | -0.057595 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0505558 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0490233 |
| RPS6 | ribosomal protein S6 | -0.0481849 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.04431 |
| PERP | PERP, TP53 apoptosis effector | -0.0382048 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0381643 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0369456 |
| TMEM62 | transmembrane protein 62 | -0.0364968 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0362895 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0362487 |
| PRELID2 | PRELI domain containing 2 | -0.035088 |
| NCKAP5 | NCK-associated protein 5 | -0.0350169 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0341565 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0338076 |
| MECOM | MDS1 and EVI1 complex locus | -0.0321707 |
| BICRAL | BICRA like chromatin remodeling complex associated protein | -0.0318551 |
| FOXP1 | forkhead box P1 | -0.0315948 |
| NPSR1 | neuropeptide S receptor 1 | -0.0312152 |
| AOPEP | aminopeptidase O (putative) | -0.0311851 |
| DIAPH3 | diaphanous-related formin 3 | -0.0311312 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0307943 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | -0.0305476 |
| SERINC5 | serine incorporator 5 | -0.0303449 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.029302 |
| RPS3 | ribosomal protein S3 | -0.0291184 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.028909 |
| RPL35A | ribosomal protein L35a | -0.0287247 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0280686 |
| MKI67 | marker of proliferation Ki-67 | -0.0278194 |
| BRCA2 | breast cancer 2, early onset | -0.0272768 |
| H1-0 | H1.0 linker histone | -0.0271135 |
| AHNAK | AHNAK nucleoprotein | -0.0266686 |
| ZDHHC20 | zinc finger, DHHC-type containing 20 | -0.0263985 |
| RASSF6 | Ras association (RalGDS/AF-6) domain family member 6 | -0.0262105 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0253956 |
| TNRC6B | trinucleotide repeat containing 6B | -0.0253586 |
| FMN1 | formin 1 | -0.0249195 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | -0.0249189 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0248671 |
| ADD3 | adducin 3 (gamma) | -0.024829 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0244818 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.023736 |
| CENPF | centromere protein F, 350/400kDa | -0.0236615 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | -0.0236495 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0235566 |
| EPHB2 | EPH receptor B2 | -0.0235367 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0228954 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0228756 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | -0.0228403 |
| TFF3 | trefoil factor 3 (intestinal) | -0.0225798 |
| ARHGEF38 | Rho guanine nucleotide exchange factor (GEF) 38 | -0.0224967 |
| WWOX | WW domain containing oxidoreductase | -0.0223881 |
| EHF | ets homologous factor | -0.0222262 |
| PTMA | prothymosin, alpha | -0.0220998 |
| RBM26 | RNA binding motif protein 26 | -0.0219108 |
| RPLP1 | ribosomal protein, large, P1 | -0.0218971 |
| RPL7L1 | ribosomal protein L7-like 1 | -0.0216997 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0216711 |
| PHF3 | PHD finger protein 3 | -0.0215505 |
| CLYBL | citrate lyase beta like | -0.0215138 |
| NEBL | nebulette | -0.0211215 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -0.021109 |
| HDAC4 | histone deacetylase 4 | -0.0210057 |
| KLF3 | Kruppel-like factor 3 (basic) | -0.0208793 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0208718 |
| RBM39 | RNA binding motif protein 39 | -0.0205642 |
| RPLP0 | ribosomal protein, large, P0 | -0.020499 |
| UBAC2 | UBA domain containing 2 | -0.0204971 |
| TNS4 | tensin 4 | -0.0202837 |
| SMYD3 | SET and MYND domain containing 3 | -0.0202539 |
| MPHOSPH8 | M-phase phosphoprotein 8 | -0.0202123 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0201837 |
| RACK1 | receptor for activated C kinase 1 | -0.0200788 |
| GNAS | GNAS complex locus | -0.0199865 |
| RPL13A | ribosomal protein L13a | -0.0196841 |
| UTY | ubiquitously transcribed tetratricopeptide repeat containing, Y-linked | -0.0195103 |
| CSTPP1 | centriolar satellite-associated tubulin polyglutamylase complex regulator 1 | -0.0194845 |
| RPL7 | ribosomal protein L7 | -0.0194366 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | -0.0193566 |
| RPL34 | ribosomal protein L34 | -0.019328 |
| SLC2A12 | solute carrier family 2 (facilitated glucose transporter), member 12 | -0.0192865 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.019137 |
| RPL11 | ribosomal protein L11 | -0.0188833 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0187732 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | -0.0187432 |
| MEIS2 | Meis homeobox 2 | -0.0186433 |
| RPS24 | ribosomal protein S24 | -0.0186102 |
| XAF1 | XIAP associated factor 1 | -0.0184998 |
| ABHD2 | abhydrolase domain containing 2 | -0.0184709 |
| CD164 | CD164 molecule, sialomucin | -0.0184676 |
| ZBTB7C | zinc finger and BTB domain containing 7C | -0.0183621 |
| RPL26 | ribosomal protein L26 | -0.0182987 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0182643 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.0182525 |
| MICU2 | mitochondrial calcium uptake 2 | -0.018215 |
| RPS8 | ribosomal protein S8 | -0.0180307 |
