| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ixazomib perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ixazomib_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FLNB | filamin B, beta | 0.110463 |
| MTSS1 | metastasis suppressor 1 | 0.11007 |
| NDRG1 | N-myc downstream regulated 1 | 0.0986984 |
| LMO7 | LIM domain 7 | 0.0959036 |
| IFITM1 | interferon induced transmembrane protein 1 | 0.0781288 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0765111 |
| IFITM3 | interferon induced transmembrane protein 3 | 0.075078 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.0742876 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | 0.0716888 |
| RASAL2 | RAS protein activator like 2 | 0.0647111 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0629813 |
| S100A10 | S100 calcium binding protein A10 | 0.0569324 |
| RPS6 | ribosomal protein S6 | 0.0563669 |
| PODXL | podocalyxin-like | 0.0561002 |
| HSPG2 | heparan sulfate proteoglycan 2 | 0.0558246 |
| TMSB10 | thymosin beta 10 | 0.055326 |
| PTMA | prothymosin, alpha | 0.0546831 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0543898 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0521285 |
| TGM2 | transglutaminase 2 | 0.0515521 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0511142 |
| JMJD1C | jumonji domain containing 1C | 0.050912 |
| IFI44L | interferon-induced protein 44-like | 0.0508134 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0501982 |
| TMSB4X | thymosin beta 4, X-linked | 0.0478009 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0462023 |
| SIK3 | SIK family kinase 3 | 0.0451056 |
| STC1 | stanniocalcin 1 | 0.0447761 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0441732 |
| DOK5 | docking protein 5 | 0.0435477 |
| CD44 | CD44 molecule (Indian blood group) | 0.0434764 |
| PALLD | palladin, cytoskeletal associated protein | 0.0424227 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0422188 |
| CDCP1 | CUB domain containing protein 1 | 0.0421733 |
| CALB1 | calbindin 1, 28kDa | 0.0419778 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0411657 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0403916 |
| CDK6 | cyclin-dependent kinase 6 | 0.0401136 |
| OSMR | oncostatin M receptor | 0.0400981 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0397563 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0390524 |
| PTK2 | protein tyrosine kinase 2 | 0.0381046 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.037611 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0373655 |
| CAV2 | caveolin 2 | 0.0372696 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0362122 |
| EFHD2 | EF-hand domain family, member D2 | 0.0360549 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0356102 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.0352344 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | 0.0346354 |
| S100A9 | S100 calcium binding protein A9 | 0.0346345 |
| CMIP | c-Maf inducing protein | 0.0343286 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0339862 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0333837 |
| MX1 | MX dynamin-like GTPase 1 | 0.0333823 |
| MEF2A | myocyte enhancer factor 2A | 0.0333721 |
| EMP1 | epithelial membrane protein 1 | 0.032927 |
| DIAPH1 | diaphanous-related formin 1 | 0.0327723 |
| EFNA5 | ephrin-A5 | 0.0325857 |
| EZR | ezrin | 0.0324968 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0324666 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0324434 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.0323728 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | 0.0323151 |
| MKI67 | marker of proliferation Ki-67 | 0.0321483 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0319521 |
| MYO10 | myosin X | 0.0318192 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0316873 |
| PCDH1 | protocadherin 1 | 0.0316147 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | 0.031253 |
| LRRC8C | leucine rich repeat containing 8 family, member C | 0.0311664 |
| SP100 | SP100 nuclear antigen | 0.0308292 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0307139 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0301029 |
| ADAR | adenosine deaminase, RNA-specific | 0.0300615 |
| TPM3 | tropomyosin 3 | 0.0298407 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0297694 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.0297528 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0296454 |
| TMOD3 | tropomodulin 3 (ubiquitous) | 0.029603 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0293642 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0291503 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.028916 |
| TPM4 | tropomyosin 4 | 0.0288349 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | 0.028782 |
| TXNRD1 | thioredoxin reductase 1 | 0.0286044 |
| RNF217 | ring finger protein 217 | 0.02847 |
| RPS25 | ribosomal protein S25 | 0.028339 |
| CNTNAP3 | contactin associated protein-like 3 | 0.028227 |
| RPLP2 | ribosomal protein, large, P2 | 0.0278735 |
| RPS21 | ribosomal protein S21 | 0.0277508 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0276656 |
| SLC35F3 | solute carrier family 35, member F3 | 0.0274837 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | 0.0274451 |
| RPL8 | ribosomal protein L8 | 0.0273442 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0272387 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0269599 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.026947 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0266377 |
| KISS1 | KiSS-1 metastasis-suppressor | 0.0265976 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CLU | clusterin | -0.189336 |
| AHNAK | AHNAK nucleoprotein | -0.0889984 |
| ENO1 | enolase 1, (alpha) | -0.064356 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0626834 |
| SQSTM1 | sequestosome 1 | -0.0552023 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0535589 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0494069 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0472959 |
| KIAA1217 | KIAA1217 | -0.0460149 |
| INTS6 | integrator complex subunit 6 | -0.04425 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0425563 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0412883 |
| UBC | ubiquitin C | -0.0412004 |
| RPS27A | ribosomal protein S27a | -0.038829 |
| OGA | O-GlcNAcase | -0.0369913 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0357783 |
| RPS3 | ribosomal protein S3 | -0.0352751 |
| MT2A | metallothionein 2A | -0.0350502 |
| RPL13A | ribosomal protein L13a | -0.0340973 |
| PRELID2 | PRELI domain containing 2 | -0.0338726 |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 | -0.0326633 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0320804 |
| RBM39 | RNA binding motif protein 39 | -0.0306833 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0289099 |
| VCL | vinculin | -0.0284089 |
| IFRD1 | interferon-related developmental regulator 1 | -0.026748 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | -0.0265204 |
| SDCBP | syndecan binding protein (syntenin) | -0.0260921 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0256724 |
| PELI2 | pellino E3 ubiquitin protein ligase family member 2 | -0.0255727 |
| LIFR | leukemia inhibitory factor receptor alpha | -0.0255148 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0254607 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0252939 |
| LDHA | lactate dehydrogenase A | -0.0252471 |
| KIF16B | kinesin family member 16B | -0.0252067 |
| KLF3 | Kruppel-like factor 3 (basic) | -0.0250776 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0250761 |
| SH3PXD2A | SH3 and PX domains 2A | -0.0249336 |
| GOLGA4 | golgin A4 | -0.024713 |
| CLIC4 | chloride intracellular channel 4 | -0.0243725 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0240963 |
| MEGF6 | multiple EGF-like-domains 6 | -0.0238577 |
| RPS12 | ribosomal protein S12 | -0.0234366 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0232832 |
| KDM4B | lysine (K)-specific demethylase 4B | -0.0230055 |
| DST | dystonin | -0.0226987 |
| NCOA3 | nuclear receptor coactivator 3 | -0.0220782 |
| ITGA10 | integrin, alpha 10 | -0.0220673 |
| CAMK2D | calcium/calmodulin-dependent protein kinase II delta | -0.0215698 |
| SHOC2 | soc-2 suppressor of clear homolog (C. elegans) | -0.0215678 |
| ADAMTS16 | ADAM metallopeptidase with thrombospondin type 1 motif, 16 | -0.0215569 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | -0.0209739 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.0208738 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | -0.020757 |
| FNIP1 | folliculin interacting protein 1 | -0.0202518 |
| PCBP2 | poly(rC) binding protein 2 | -0.019692 |
| ZNF217 | zinc finger protein 217 | -0.0195775 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | -0.0194807 |
| DENND2C | DENN/MADD domain containing 2C | -0.0190643 |
| PLXNA2 | plexin A2 | -0.018971 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0186974 |
| WLS | wntless Wnt ligand secretion mediator | -0.0185079 |
| RPL37A | ribosomal protein L37a | -0.0184702 |
| SOX13 | SRY (sex determining region Y)-box 13 | -0.0184324 |
| SPAG9 | sperm associated antigen 9 | -0.0184162 |
| RPS13 | ribosomal protein S13 | -0.0182875 |
| PHF3 | PHD finger protein 3 | -0.0180217 |
| PPP1R10 | protein phosphatase 1, regulatory subunit 10 | -0.0179709 |
| SVIL | supervillin | -0.0179608 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0178186 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0177277 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0176552 |
| RSPO2 | R-spondin 2 | -0.0175835 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | -0.0174995 |
| RALGAPB | Ral GTPase activating protein, beta subunit (non-catalytic) | -0.0174781 |
| GSN | gelsolin | -0.0174019 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | -0.0173478 |
| PKM | pyruvate kinase, muscle | -0.0172523 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | -0.0170751 |
| ERGIC3 | ERGIC and golgi 3 | -0.0169648 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.016742 |
| CAPRIN2 | caprin family member 2 | -0.0166861 |
| FLNA | filamin A, alpha | -0.0165821 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.0165661 |
| CDC73 | cell division cycle 73 | -0.0164509 |
| DMXL1 | Dmx-like 1 | -0.016338 |
| ANKH | ANKH inorganic pyrophosphate transport regulator | -0.0162738 |
| WDR26 | WD repeat domain 26 | -0.0160835 |
| ATXN1 | ataxin 1 | -0.0157899 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0157337 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0157224 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0154685 |
| LGR6 | leucine-rich repeat containing G protein-coupled receptor 6 | -0.0153538 |
| CANX | calnexin | -0.0153426 |
| RIGI | RNA sensor RIG-I | -0.0152983 |
| IER3 | immediate early response 3 | -0.0152063 |
| ADSS2 | adenylosuccinate synthase 2 | -0.0151147 |
| RPL7 | ribosomal protein L7 | -0.0150631 |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like | -0.0149717 |
| TNRC6B | trinucleotide repeat containing 6B | -0.0148828 |
