| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ixazomib perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ixazomib_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DST | dystonin | 0.113948 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0788251 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.056721 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0465298 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0441288 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0440809 |
| HDAC9 | histone deacetylase 9 | 0.0398228 |
| CANX | calnexin | 0.0397644 |
| CAPRIN2 | caprin family member 2 | 0.0386674 |
| MYOF | myoferlin | 0.0379614 |
| SQSTM1 | sequestosome 1 | 0.0363332 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0331199 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0317973 |
| INTS6 | integrator complex subunit 6 | 0.0311613 |
| RUNX1 | runt-related transcription factor 1 | 0.0291168 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0289624 |
| PRELID2 | PRELI domain containing 2 | 0.0288338 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0286107 |
| LDHA | lactate dehydrogenase A | 0.0281977 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0276803 |
| TP63 | tumor protein p63 | 0.0273765 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0268899 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 | 0.0257721 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0246096 |
| CSMD3 | CUB and Sushi multiple domains 3 | 0.0245442 |
| AEBP2 | AE binding protein 2 | 0.0244793 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0244283 |
| AHNAK | AHNAK nucleoprotein | 0.0243006 |
| HDLBP | high density lipoprotein binding protein | 0.0241225 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0237288 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0236561 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0235994 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0227183 |
| NEK10 | NIMA-related kinase 10 | 0.0225124 |
| KDM4B | lysine (K)-specific demethylase 4B | 0.0219144 |
| SPAG9 | sperm associated antigen 9 | 0.0215831 |
| RPS3 | ribosomal protein S3 | 0.0211542 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0211314 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0206121 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0200918 |
| PLK2 | polo-like kinase 2 | 0.020065 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0199812 |
| APP | amyloid beta (A4) precursor protein | 0.0198668 |
| CD44 | CD44 molecule (Indian blood group) | 0.0198537 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0198496 |
| EGFR | epidermal growth factor receptor | 0.0197846 |
| GOLGB1 | golgin B1 | 0.0192126 |
| RPS12 | ribosomal protein S12 | 0.0191724 |
| FMNL2 | formin-like 2 | 0.0191255 |
| LYST | lysosomal trafficking regulator | 0.0189861 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0189783 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0187247 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0185235 |
| TMSB4X | thymosin beta 4, X-linked | 0.0184363 |
| HOMER1 | homer scaffolding protein 1 | 0.0182453 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.018056 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0178602 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0174622 |
| CADM2 | cell adhesion molecule 2 | 0.0173865 |
| VCL | vinculin | 0.017376 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0171769 |
| FNIP1 | folliculin interacting protein 1 | 0.0171483 |
| TNS3 | tensin 3 | 0.0168629 |
| MCL1 | myeloid cell leukemia 1 | 0.0167327 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.0163897 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0161332 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.015784 |
| LOXL2 | lysyl oxidase-like 2 | 0.0157449 |
| ASPH | aspartate beta-hydroxylase | 0.0155896 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | 0.0152885 |
| PLEC | plectin | 0.0150635 |
| SP100 | SP100 nuclear antigen | 0.0149661 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0149651 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0149139 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0148131 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0147122 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0146163 |
| PHF3 | PHD finger protein 3 | 0.0142868 |
| EPHA4 | EPH receptor A4 | 0.0141938 |
| OGA | O-GlcNAcase | 0.0140705 |
| RPL13A | ribosomal protein L13a | 0.0140227 |
| SMYD3 | SET and MYND domain containing 3 | 0.0140219 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0138633 |
| GNGT1 | guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 | 0.0137307 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0135723 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0135328 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | 0.013489 |
| GYS1 | glycogen synthase 1 (muscle) | 0.0134759 |
| PODXL | podocalyxin-like | 0.0133217 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0132402 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0130835 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | 0.0129421 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0128919 |
| EFNA5 | ephrin-A5 | 0.0127951 |
| DOCK1 | dedicator of cytokinesis 1 | 0.0127091 |
| ACTN1 | actinin, alpha 1 | 0.0126376 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0122601 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0122062 |
| PCBP2 | poly(rC) binding protein 2 | 0.0121129 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0119668 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | -0.191519 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.161257 |
| VIM | vimentin | -0.12691 |
| TMSB10 | thymosin beta 10 | -0.0966454 |
| POTEF | POTE ankyrin domain family, member F | -0.0896009 |
| PTMA | prothymosin, alpha | -0.062893 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0510161 |
| SRGN | serglycin | -0.0446357 |
| MT1X | metallothionein 1X | -0.0443355 |
| RPS19 | ribosomal protein S19 | -0.0438127 |
| MT1E | metallothionein 1E | -0.0416259 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0404708 |
| RAI1 | retinoic acid induced 1 | -0.0404266 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0394462 |
| TXNRD1 | thioredoxin reductase 1 | -0.0382286 |
| RPL23 | ribosomal protein L23 | -0.0363016 |
| CENPF | centromere protein F, 350/400kDa | -0.0355339 |
| HMGA1 | high mobility group AT-hook 1 | -0.0335539 |
| RTN4 | reticulon 4 | -0.0325515 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0324717 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0313814 |
| TNFRSF6B | tumor necrosis factor receptor superfamily, member 6b, decoy | -0.0301864 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.0285738 |
| FOSL1 | FOS-like antigen 1 | -0.0284272 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0280868 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0280393 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0279293 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.027883 |
| RBM25 | RNA binding motif protein 25 | -0.0273263 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0264959 |
| FTL | ferritin, light polypeptide | -0.0260564 |
| PFN1 | profilin 1 | -0.0259625 |
| MKI67 | marker of proliferation Ki-67 | -0.0256373 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0245882 |
| ACTG1 | actin gamma 1 | -0.0245354 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0244064 |
| S100A9 | S100 calcium binding protein A9 | -0.0233198 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0231043 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0231007 |
| RPLP2 | ribosomal protein, large, P2 | -0.0230957 |
| RPL28 | ribosomal protein L28 | -0.0230605 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0229752 |
| RPL35 | ribosomal protein L35 | -0.0224137 |
| TMEM41B | transmembrane protein 41B | -0.0217183 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0211431 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.020827 |
| TPI1 | triosephosphate isomerase 1 | -0.0203433 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0202602 |
| S100A6 | S100 calcium binding protein A6 | -0.0202252 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.020008 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0196349 |
| YBX3 | Y box binding protein 3 | -0.0194217 |
| RPL36 | ribosomal protein L36 | -0.0193486 |
| EGR1 | early growth response 1 | -0.0192875 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | -0.0192198 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0189439 |
| SRPK2 | SRSF protein kinase 2 | -0.0188787 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | -0.0187686 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.018743 |
| XPO1 | exportin 1 | -0.0187119 |
| RPS6 | ribosomal protein S6 | -0.0182403 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0179354 |
| UBXN4 | UBX domain protein 4 | -0.0179049 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.017799 |
| RPL32 | ribosomal protein L32 | -0.0177044 |
| HLA-B | major histocompatibility complex, class I, B | -0.0172875 |
| CCNL1 | cyclin L1 | -0.017129 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | -0.0170891 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | -0.0169963 |
| YBX1 | Y box binding protein 1 | -0.0169309 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0167354 |
| MYADM | myeloid-associated differentiation marker | -0.0164969 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0164368 |
| DIAPH3 | diaphanous-related formin 3 | -0.0164346 |
| PRDX1 | peroxiredoxin 1 | -0.0164324 |
| RPS21 | ribosomal protein S21 | -0.0163615 |
| GCLM | glutamate-cysteine ligase, modifier subunit | -0.0162843 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0160792 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.016063 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.015942 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0159238 |
| GART | phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase | -0.01582 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0158002 |
| ADAM17 | ADAM metallopeptidase domain 17 | -0.0157537 |
| PPIG | peptidylprolyl isomerase G (cyclophilin G) | -0.0156367 |
| RAB27B | RAB27B, member RAS oncogene family | -0.0156065 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0155525 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | -0.0155016 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.0154222 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0152463 |
| TAPBP | TAP binding protein (tapasin) | -0.0151435 |
| RPS14 | ribosomal protein S14 | -0.0150002 |
| S100A11 | S100 calcium binding protein A11 | -0.01498 |
| CBX3 | chromobox homolog 3 | -0.0149623 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | -0.0148499 |
| RPL12 | ribosomal protein L12 | -0.014844 |
| RPS23 | ribosomal protein S23 | -0.0147565 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0145101 |
| TPM4 | tropomyosin 4 | -0.0144812 |
| RPLP1 | ribosomal protein, large, P1 | -0.01445 |
