| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ixazomib perturbation in NCI-H1573 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Ixazomib_NCI-H1573 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SPAG9 | sperm associated antigen 9 | 0.0832262 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0749454 |
| FAM13A | family with sequence similarity 13, member A | 0.073116 |
| MCL1 | myeloid cell leukemia 1 | 0.07115 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.066488 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0631423 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0626551 |
| TOP1 | topoisomerase (DNA) I | 0.0610343 |
| SLTM | SAFB-like, transcription modulator | 0.0605201 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0584435 |
| RUNX1 | runt-related transcription factor 1 | 0.0572496 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0558278 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0557732 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0545486 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0540761 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0537053 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0534138 |
| ARRDC3 | arrestin domain containing 3 | 0.0530083 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0529791 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0516883 |
| NDRG1 | N-myc downstream regulated 1 | 0.0490497 |
| PCBP2 | poly(rC) binding protein 2 | 0.0471603 |
| MT2A | metallothionein 2A | 0.0454408 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0444416 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0440133 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.043662 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0429235 |
| HELZ | helicase with zinc finger | 0.0398276 |
| UVRAG | UV radiation resistance associated | 0.0384194 |
| RAB7A | RAB7A, member RAS oncogene family | 0.038321 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0362915 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0356279 |
| DTNA | dystrobrevin, alpha | 0.0356143 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0351788 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.0347049 |
| HYOU1 | hypoxia up-regulated 1 | 0.0343443 |
| BRD2 | bromodomain containing 2 | 0.0342275 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0340937 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0338903 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.03378 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0334764 |
| MKI67 | marker of proliferation Ki-67 | 0.0328756 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0324124 |
| NPTN | neuroplastin | 0.0323165 |
| CSNK1E | casein kinase 1, epsilon | 0.0322319 |
| ANKRD37 | ankyrin repeat domain 37 | 0.0313898 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0311881 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0311049 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0309996 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0302947 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0301229 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0299385 |
| WDR45B | WD repeat domain 45B | 0.0296373 |
| INTS6 | integrator complex subunit 6 | 0.0295197 |
| TMEM165 | transmembrane protein 165 | 0.0291148 |
| OGA | O-GlcNAcase | 0.0288297 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0286496 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.028405 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0283513 |
| UBC | ubiquitin C | 0.0283302 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0279041 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0275437 |
| MAP7 | microtubule-associated protein 7 | 0.0273958 |
| ATP13A3 | ATPase type 13A3 | 0.0273203 |
| NGLY1 | N-glycanase 1 | 0.0268576 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0266295 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0262829 |
| CYLD | cylindromatosis (turban tumor syndrome) | 0.0260449 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0260361 |
| MORF4L2 | mortality factor 4 like 2 | 0.0258148 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.025702 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.025679 |
| RNF145 | ring finger protein 145 | 0.0252007 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0248813 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0248692 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0244369 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0242247 |
| WASF2 | WAS protein family, member 2 | 0.0241907 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | 0.0237923 |
| HBP1 | HMG-box transcription factor 1 | 0.023778 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0236878 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.023685 |
| GPATCH2L | G patch domain containing 2-like | 0.023539 |
| AP1G1 | adaptor-related protein complex 1, gamma 1 subunit | 0.0232221 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0231108 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0230339 |
| USP34 | ubiquitin specific peptidase 34 | 0.0229642 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0223908 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0223713 |
| ECT2 | epithelial cell transforming 2 | 0.0222643 |
| PER1 | period circadian clock 1 | 0.0219649 |
| SRP54 | signal recognition particle 54kDa | 0.0218444 |
| YTHDC1 | YTH domain containing 1 | 0.0215952 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0214851 |
| ANKRD11 | ankyrin repeat domain 11 | 0.021426 |
| BMP6 | bone morphogenetic protein 6 | 0.0213958 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0213833 |
| LRCH3 | leucine-rich repeats and calponin homology (CH) domain containing 3 | 0.0213452 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0212877 |
| ABLIM1 | actin binding LIM protein 1 | 0.021223 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ASPH | aspartate beta-hydroxylase | -0.116467 |
| TXNRD1 | thioredoxin reductase 1 | -0.0882798 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0864436 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0784399 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0735689 |
| TMSB10 | thymosin beta 10 | -0.0720597 |
| EFNA5 | ephrin-A5 | -0.0665547 |
| EGFR | epidermal growth factor receptor | -0.0658518 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0644395 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.0639981 |
| ACTG1 | actin gamma 1 | -0.0614263 |
| LRP1B | low density lipoprotein receptor-related protein 1B | -0.0603486 |
| LAMC2 | laminin, gamma 2 | -0.060311 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0584547 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0561194 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.055344 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0505537 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | -0.0497462 |
| LMO7 | LIM domain 7 | -0.0488512 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0478544 |
| AHNAK | AHNAK nucleoprotein | -0.047763 |
| CST3 | cystatin C | -0.0470402 |
| OSMR | oncostatin M receptor | -0.0469366 |
| KRT7 | keratin 7, type II | -0.0454591 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0442293 |
| CCND1 | cyclin D1 | -0.0415121 |
| KRT18 | keratin 18, type I | -0.0390379 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0387658 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0378527 |
| DSPP | dentin sialophosphoprotein | -0.0376362 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0373769 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0354204 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0348698 |
| RPS3 | ribosomal protein S3 | -0.0348052 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0347865 |
| ENO1 | enolase 1, (alpha) | -0.0340455 |
| TNS3 | tensin 3 | -0.0338844 |
| AGR2 | anterior gradient 2 | -0.0337836 |
| LDHA | lactate dehydrogenase A | -0.0322608 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0315841 |
| RAB10 | RAB10, member RAS oncogene family | -0.0313614 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0313415 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0312715 |
| RAB27B | RAB27B, member RAS oncogene family | -0.0308193 |
| RPL37A | ribosomal protein L37a | -0.0303295 |
| ANXA2 | annexin A2 | -0.0283774 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0281691 |
| KRT19 | keratin 19, type I | -0.0279205 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0278659 |
| FOXP1 | forkhead box P1 | -0.0273542 |
| TRIM56 | tripartite motif containing 56 | -0.0270698 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0268188 |
| RPS27A | ribosomal protein S27a | -0.0267138 |
| LGALS12 | lectin, galactoside-binding, soluble, 12 | -0.0266552 |
| S100A10 | S100 calcium binding protein A10 | -0.0263239 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.0259863 |
| PRDX1 | peroxiredoxin 1 | -0.0259594 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0259076 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0256499 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0254805 |
| EGR1 | early growth response 1 | -0.0254688 |
| BMP7 | bone morphogenetic protein 7 | -0.0252761 |
| CPE | carboxypeptidase E | -0.0244327 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0242007 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.0240263 |
| LAMA4 | laminin, alpha 4 | -0.024003 |
| PM20D1 | peptidase M20 domain containing 1 | -0.0236159 |
| RPL35A | ribosomal protein L35a | -0.0235728 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | -0.0230683 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0229198 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0224718 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0221748 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0220618 |
| ETV6 | ets variant 6 | -0.0217375 |
| CUX1 | cut-like homeobox 1 | -0.0216853 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | -0.0216203 |
| GNAS | GNAS complex locus | -0.0215679 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.021209 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0211673 |
| NTN4 | netrin 4 | -0.0206596 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0206578 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0205948 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0205295 |
| HLA-B | major histocompatibility complex, class I, B | -0.0205217 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0203415 |
| SCEL | sciellin | -0.0203012 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.020216 |
| RIN2 | Ras and Rab interactor 2 | -0.0201854 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.0200555 |
| AHR | aryl hydrocarbon receptor | -0.0198486 |
| PGK1 | phosphoglycerate kinase 1 | -0.0197688 |
| ADGRF1 | adhesion G protein-coupled receptor F1 | -0.0197481 |
| CHML | choroideremia-like (Rab escort protein 2) | -0.0196848 |
| S100A6 | S100 calcium binding protein A6 | -0.0195897 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0194735 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0192294 |
| NCOA3 | nuclear receptor coactivator 3 | -0.0191872 |
| NEBL | nebulette | -0.0190373 |
| RPS12 | ribosomal protein S12 | -0.0188774 |
| TPM4 | tropomyosin 4 | -0.0188593 |
