| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ixazomib perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Ixazomib_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EFNA5 | ephrin-A5 | 0.0954687 |
| FAM20C | family with sequence similarity 20, member C | 0.0912988 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0732548 |
| CDH13 | cadherin 13 | 0.0730439 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0708009 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0686311 |
| INTS6 | integrator complex subunit 6 | 0.0659934 |
| NAV2 | neuron navigator 2 | 0.0643891 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.0624088 |
| SMAD3 | SMAD family member 3 | 0.0592636 |
| LOXL2 | lysyl oxidase-like 2 | 0.0549337 |
| SEPTIN9 | septin 9 | 0.0542956 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0519223 |
| AADAC | arylacetamide deacetylase | 0.0513495 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0495515 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0487063 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0485519 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0455028 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0434076 |
| EGFR | epidermal growth factor receptor | 0.0412455 |
| TGFB1 | transforming growth factor, beta 1 | 0.0396584 |
| ATXN1 | ataxin 1 | 0.0395049 |
| HMGA2 | high mobility group AT-hook 2 | 0.0393429 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0391737 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0388866 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0370728 |
| ADAMTS14 | ADAM metallopeptidase with thrombospondin type 1 motif, 14 | 0.0366024 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0326132 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.0325455 |
| PRELID2 | PRELI domain containing 2 | 0.031918 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | 0.0314512 |
| TGM2 | transglutaminase 2 | 0.03142 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0308352 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0301582 |
| LOX | lysyl oxidase | 0.0301203 |
| IFI44L | interferon-induced protein 44-like | 0.0292232 |
| NPAS2 | neuronal PAS domain protein 2 | 0.028922 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.028602 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0283601 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0272363 |
| VEGFA | vascular endothelial growth factor A | 0.0269691 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0266606 |
| ASPH | aspartate beta-hydroxylase | 0.0263 |
| RPL31 | ribosomal protein L31 | 0.0260701 |
| SP100 | SP100 nuclear antigen | 0.0256547 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.025569 |
| ATG7 | autophagy related 7 | 0.0252419 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0252355 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0249151 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0247951 |
| EFCAB13 | EF-hand calcium binding domain 13 | 0.0247737 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0247405 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0247386 |
| ECE1 | endothelin converting enzyme 1 | 0.0244651 |
| SQSTM1 | sequestosome 1 | 0.0244566 |
| RPS25 | ribosomal protein S25 | 0.0240262 |
| MX1 | MX dynamin-like GTPase 1 | 0.0236404 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0233998 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | 0.0232717 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0232631 |
| VCL | vinculin | 0.0227903 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0226718 |
| GALNT18 | polypeptide N-acetylgalactosaminyltransferase 18 | 0.022585 |
| RUNX1 | runt-related transcription factor 1 | 0.021648 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0216083 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0215427 |
| HIP1 | huntingtin interacting protein 1 | 0.0214049 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0212149 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0212017 |
| CEP250 | centrosomal protein 250kDa | 0.0209112 |
| ZNF638 | zinc finger protein 638 | 0.0206113 |
| CANX | calnexin | 0.0204986 |
| PLEC | plectin | 0.0204743 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0204444 |
| RPL35A | ribosomal protein L35a | 0.0203829 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.020377 |
| SHISA5 | shisa family member 5 | 0.0203512 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0201822 |
| CCDC138 | coiled-coil domain containing 138 | 0.020172 |
| ARHGAP22 | Rho GTPase activating protein 22 | 0.0200134 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0199664 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0198536 |
| MCL1 | myeloid cell leukemia 1 | 0.0197689 |
| NDRG1 | N-myc downstream regulated 1 | 0.0197191 |
| HM13 | histocompatibility (minor) 13 | 0.019534 |
| LARP1B | La ribonucleoprotein domain family, member 1B | 0.0193425 |
| RARB | retinoic acid receptor, beta | 0.0192822 |
| ARFGEF3 | ARFGEF family member 3 | 0.019238 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.0191928 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.019018 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0188552 |
| PYGL | phosphorylase, glycogen, liver | 0.018776 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | 0.0187721 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0185174 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0184884 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | 0.0184695 |
| SMYD3 | SET and MYND domain containing 3 | 0.0183704 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0183545 |
| DENND1A | DENN/MADD domain containing 1A | 0.0183312 |
| AVIL | advillin | 0.0183262 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.161409 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.159343 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.10571 |
| TMSB10 | thymosin beta 10 | -0.0898585 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.088512 |
| FN1 | fibronectin 1 | -0.0768179 |
| OSMR | oncostatin M receptor | -0.0666612 |
| FTL | ferritin, light polypeptide | -0.0629554 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0628516 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.0624955 |
| S100A6 | S100 calcium binding protein A6 | -0.0610466 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0607596 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0589066 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0574704 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0531615 |
| VIM | vimentin | -0.0508047 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0493085 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0470657 |
| RAB27B | RAB27B, member RAS oncogene family | -0.046115 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0443568 |
| RBM39 | RNA binding motif protein 39 | -0.0442873 |
| MEF2A | myocyte enhancer factor 2A | -0.0442562 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0436958 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0420991 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | -0.0416761 |
| NPC1 | Niemann-Pick disease, type C1 | -0.04117 |
| ATP13A3 | ATPase type 13A3 | -0.0402407 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0400691 |
| GLCCI1 | glucocorticoid induced 1 | -0.0395234 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0379693 |
| MAP1B | microtubule-associated protein 1B | -0.0375887 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0364446 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0361522 |
| JMJD1C | jumonji domain containing 1C | -0.0359046 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0350996 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0350184 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0341818 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0335614 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0335219 |
| SNX9 | sorting nexin 9 | -0.0333291 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | -0.0326419 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.031555 |
| HAS2 | hyaluronan synthase 2 | -0.0314183 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0308198 |
| RPLP1 | ribosomal protein, large, P1 | -0.0306703 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0304362 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.0298935 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0297755 |
| RNF24 | ring finger protein 24 | -0.0295681 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0293745 |
| POTEF | POTE ankyrin domain family, member F | -0.0289606 |
| SIK3 | SIK family kinase 3 | -0.0289239 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.028576 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | -0.0279749 |
| EGR1 | early growth response 1 | -0.027703 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0276445 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0274171 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0272985 |
| NRP1 | neuropilin 1 | -0.0271977 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0271669 |
| RAB1A | RAB1A, member RAS oncogene family | -0.027045 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | -0.0268703 |
| ITGAV | integrin, alpha V | -0.0267415 |
| HEG1 | heart development protein with EGF-like domains 1 | -0.0264858 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.026464 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0262444 |
| RPS21 | ribosomal protein S21 | -0.026196 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0261261 |
| USP3 | ubiquitin specific peptidase 3 | -0.0260085 |
| ADD3 | adducin 3 (gamma) | -0.0258687 |
| ARID3B | AT rich interactive domain 3B (BRIGHT-like) | -0.0258362 |
| KLF6 | Kruppel-like factor 6 | -0.0255269 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | -0.0255109 |
| MECOM | MDS1 and EVI1 complex locus | -0.025269 |
| OXSR1 | oxidative stress responsive 1 | -0.0248015 |
| TPI1 | triosephosphate isomerase 1 | -0.0247549 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0247262 |
| DAAM1 | dishevelled associated activator of morphogenesis 1 | -0.0244626 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0244571 |
| RUNX2 | runt-related transcription factor 2 | -0.0243088 |
| PTBP2 | polypyrimidine tract binding protein 2 | -0.0241641 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0240024 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0238852 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0238077 |
| SYAP1 | synapse associated protein 1 | -0.0232862 |
| TSPAN5 | tetraspanin 5 | -0.0230837 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | -0.0229234 |
| PCNX1 | pecanex 1 | -0.0227625 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | -0.0226887 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0225843 |
| PTMA | prothymosin, alpha | -0.0225339 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0224316 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.022427 |
| RPS3 | ribosomal protein S3 | -0.0223847 |
| PFN1 | profilin 1 | -0.0222915 |
| GSTP1 | glutathione S-transferase pi 1 | -0.0217492 |
| ABI1 | abl-interactor 1 | -0.0216937 |
| USP34 | ubiquitin specific peptidase 34 | -0.0215374 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0213881 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0212955 |
