| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ixazomib perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ixazomib_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0963185 |
| FN1 | fibronectin 1 | 0.0880679 |
| KYNU | kynureninase | 0.082201 |
| TXNRD1 | thioredoxin reductase 1 | 0.0768766 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.073213 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0714984 |
| CANX | calnexin | 0.068534 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | 0.0672558 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0664144 |
| EFNA5 | ephrin-A5 | 0.063762 |
| NCAM1 | neural cell adhesion molecule 1 | 0.0632004 |
| SP100 | SP100 nuclear antigen | 0.0595862 |
| MYOF | myoferlin | 0.0578381 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0575174 |
| PDE10A | phosphodiesterase 10A | 0.0547545 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0546976 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0519268 |
| LSAMP | limbic system-associated membrane protein | 0.0514007 |
| FOXP1 | forkhead box P1 | 0.0497 |
| ASPH | aspartate beta-hydroxylase | 0.0496543 |
| S100A6 | S100 calcium binding protein A6 | 0.0492627 |
| MLEC | malectin | 0.0488981 |
| TXNIP | thioredoxin interacting protein | 0.0488354 |
| SEPTIN9 | septin 9 | 0.0486436 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.0474049 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0473595 |
| RPL32 | ribosomal protein L32 | 0.0457678 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.045026 |
| NRCAM | neuronal cell adhesion molecule | 0.0446371 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | 0.0445734 |
| EML4 | echinoderm microtubule associated protein like 4 | 0.0443596 |
| MORF4L2 | mortality factor 4 like 2 | 0.0443082 |
| SLC38A1 | solute carrier family 38, member 1 | 0.0442847 |
| ANKLE2 | ankyrin repeat and LEM domain containing 2 | 0.0442466 |
| NAV2 | neuron navigator 2 | 0.043799 |
| COL4A5 | collagen, type IV, alpha 5 | 0.0437343 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0426472 |
| TJP1 | tight junction protein 1 | 0.0426209 |
| PGK1 | phosphoglycerate kinase 1 | 0.0425661 |
| SHTN1 | shootin 1 | 0.0418663 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0417998 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | 0.0387946 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | 0.0382672 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0380907 |
| CFDP1 | craniofacial development protein 1 | 0.0380814 |
| CARD16 | caspase recruitment domain family, member 16 | 0.0379384 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0375743 |
| ENO1 | enolase 1, (alpha) | 0.0374305 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0367486 |
| PM20D1 | peptidase M20 domain containing 1 | 0.0360183 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | 0.0360161 |
| SUCO | SUN domain containing ossification factor | 0.0359789 |
| RPS3 | ribosomal protein S3 | 0.0356488 |
| SMYD3 | SET and MYND domain containing 3 | 0.0355538 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0354277 |
| SETD2 | SET domain containing 2 | 0.0348728 |
| GOLGA4 | golgin A4 | 0.0348104 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0348029 |
| MACC1 | metastasis associated in colon cancer 1 | 0.034496 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.0334774 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0333252 |
| RPL19 | ribosomal protein L19 | 0.0330702 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0329708 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | 0.0324204 |
| OLA1 | Obg-like ATPase 1 | 0.0322982 |
| SAMD12 | sterile alpha motif domain containing 12 | 0.0322746 |
| SDC4 | syndecan 4 | 0.0321401 |
| SPATA13 | spermatogenesis associated 13 | 0.0319221 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.031867 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0316494 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.0311366 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0310259 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0308785 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0307951 |
| CDC73 | cell division cycle 73 | 0.0305777 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | 0.0305447 |
| MYO6 | myosin VI | 0.0304451 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0303346 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0302212 |
| FAM107B | family with sequence similarity 107, member B | 0.0300892 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | 0.0299179 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0298155 |
| HELZ | helicase with zinc finger | 0.0295464 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0294359 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0292844 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0283464 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.0283023 |
| SETD5 | SET domain containing 5 | 0.0281641 |
| RPLP1 | ribosomal protein, large, P1 | 0.0279555 |
| RPS12 | ribosomal protein S12 | 0.0277292 |
| DSPP | dentin sialophosphoprotein | 0.0272966 |
| STK4 | serine/threonine kinase 4 | 0.027169 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0270543 |
| PRELID2 | PRELI domain containing 2 | 0.027029 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0267027 |
| PPP1R2 | protein phosphatase 1, regulatory (inhibitor) subunit 2 | 0.0264373 |
| SPIDR | scaffolding protein involved in DNA repair | 0.0261187 |
| RBM39 | RNA binding motif protein 39 | 0.0261016 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0255707 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0254949 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GRB10 | growth factor receptor-bound protein 10 | -0.174489 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.128848 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0895179 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | -0.0889345 |
| MUC16 | mucin 16, cell surface associated | -0.0863253 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0856495 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0840811 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0821951 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0764413 |
| STC1 | stanniocalcin 1 | -0.0717265 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0664156 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0636132 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0627689 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0621917 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -0.0609525 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0580189 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0570577 |
| FBXO11 | F-box protein 11 | -0.0568595 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0540431 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.0525637 |
| MYO1E | myosin IE | -0.0509192 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | -0.0505835 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0478166 |
| TUFT1 | tuftelin 1 | -0.0477923 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.047659 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0476193 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0475542 |
| NF1 | neurofibromin 1 | -0.0475076 |
| OSMR | oncostatin M receptor | -0.0462712 |
| TMSB10 | thymosin beta 10 | -0.0456218 |
| AHNAK | AHNAK nucleoprotein | -0.0454949 |
| NCOR2 | nuclear receptor corepressor 2 | -0.0454164 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0450289 |
| ATOSA | atos homolog A | -0.0442199 |
| EGFR | epidermal growth factor receptor | -0.0436137 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0434638 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0432409 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0428575 |
| EXOC6B | exocyst complex component 6B | -0.0424656 |
| MCL1 | myeloid cell leukemia 1 | -0.0422418 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0420664 |
| KIAA1217 | KIAA1217 | -0.0406647 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0401827 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0400152 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.039229 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0392154 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0385063 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0375613 |
| AK1 | adenylate kinase 1 | -0.0374842 |
| NEK7 | NIMA-related kinase 7 | -0.0373221 |
| MAP7 | microtubule-associated protein 7 | -0.0371179 |
| NDRG1 | N-myc downstream regulated 1 | -0.0364807 |
| ERBIN | erbb2 interacting protein | -0.0361277 |
| ABHD17C | abhydrolase domain containing 17C | -0.0356715 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | -0.0354419 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0351723 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0336034 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0330907 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0327761 |
| ANXA2 | annexin A2 | -0.032255 |
| LMO7 | LIM domain 7 | -0.0316343 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.031629 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0314011 |
| GPC6 | glypican 6 | -0.0307399 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0304126 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0303978 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0303774 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0301698 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0300969 |
| SBF2 | SET binding factor 2 | -0.0300699 |
| PTMA | prothymosin, alpha | -0.029566 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | -0.0295127 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0293655 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.0285993 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0284773 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0280771 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0277907 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0276681 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0276099 |
| ZFC3H1 | zinc finger, C3H1-type containing | -0.0275317 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0274529 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0274271 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | -0.0273779 |
| MYO5B | myosin VB | -0.0272355 |
| ACTG1 | actin gamma 1 | -0.0271406 |
| LOXL2 | lysyl oxidase-like 2 | -0.0270477 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0267378 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0266752 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0266529 |
| MXD1 | MAX dimerization protein 1 | -0.0264668 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0263894 |
| RAB8B | RAB8B, member RAS oncogene family | -0.026297 |
| TPM4 | tropomyosin 4 | -0.0261702 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0260298 |
| RIGI | RNA sensor RIG-I | -0.0257681 |
| JUP | junction plakoglobin | -0.0255101 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0252079 |
| MED13L | mediator complex subunit 13-like | -0.02507 |
| RNF213 | ring finger protein 213 | -0.0250404 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0248392 |
