| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ixazomib perturbation in NCI-H596 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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69 genes differentially expressed following the Ixazomib_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.171519 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.154531 |
| FN1 | fibronectin 1 | 0.145713 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.143648 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.112762 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.111258 |
| RPS8 | ribosomal protein S8 | 0.103136 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.100662 |
| GPC6 | glypican 6 | 0.0996124 |
| GOLGA4 | golgin A4 | 0.0985984 |
| MYO1E | myosin IE | 0.0971125 |
| LDHA | lactate dehydrogenase A | 0.0964168 |
| ENO1 | enolase 1, (alpha) | 0.0939869 |
| ASPH | aspartate beta-hydroxylase | 0.0930251 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0858611 |
| PGK1 | phosphoglycerate kinase 1 | 0.0833342 |
| ANXA2 | annexin A2 | 0.0829794 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0760213 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.0676201 |
| NDRG1 | N-myc downstream regulated 1 | 0.0637744 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0545927 |
| DST | dystonin | 0.0545554 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0446147 |
| EFNA5 | ephrin-A5 | 0.0409397 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0347481 |
| PDE10A | phosphodiesterase 10A | 0.027202 |
| HMGA2 | high mobility group AT-hook 2 | 0.0258347 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0256302 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0206636 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0199585 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0177961 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0152605 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0134818 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.00147589 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.341737 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.141418 |
| EGFR | epidermal growth factor receptor | -0.119244 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.118071 |
| PRRC2C | proline-rich coiled-coil 2C | -0.114896 |
| CDH13 | cadherin 13 | -0.0995412 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.090337 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0743187 |
| AOPEP | aminopeptidase O (putative) | -0.07112 |
| PARD3 | par-3 family cell polarity regulator | -0.0656463 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0641567 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0614472 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.061011 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0544697 |
| PTMA | prothymosin, alpha | -0.0524558 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.050493 |
| MT2A | metallothionein 2A | -0.0492733 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0466903 |
| BBX | bobby sox homolog (Drosophila) | -0.0449018 |
| SLC2A13 | solute carrier family 2 (facilitated glucose transporter), member 13 | -0.0438739 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0428147 |
| RPS6 | ribosomal protein S6 | -0.041637 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0385785 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0309409 |
| TCF12 | transcription factor 12 | -0.0242868 |
| APP | amyloid beta (A4) precursor protein | -0.0231537 |
| TMSB10 | thymosin beta 10 | -0.0224128 |
| PCBP2 | poly(rC) binding protein 2 | -0.0157082 |
| VIM | vimentin | -0.0153979 |
| RPS3 | ribosomal protein S3 | -0.0147331 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0126129 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0124612 |
| FTL | ferritin, light polypeptide | -0.0111312 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.00791139 |
| RPS12 | ribosomal protein S12 | -0.00398538 |
