| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ixazomib perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Ixazomib_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.238822 |
| EGFR | epidermal growth factor receptor | 0.0846908 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0726782 |
| VEGFA | vascular endothelial growth factor A | 0.0703205 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0627731 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0508707 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.050373 |
| FNDC3B | fibronectin type III domain containing 3B | 0.047745 |
| TNS3 | tensin 3 | 0.0471245 |
| CALD1 | caldesmon 1 | 0.0463591 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0457179 |
| CALR | calreticulin | 0.0445733 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0443955 |
| NRXN3 | neurexin 3 | 0.0438255 |
| CDH13 | cadherin 13 | 0.0434016 |
| IL6 | interleukin 6 | 0.0423631 |
| ARRDC3 | arrestin domain containing 3 | 0.041502 |
| COL6A1 | collagen, type VI, alpha 1 | 0.0403532 |
| COL5A1 | collagen, type V, alpha 1 | 0.0390625 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0367442 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0366228 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0352938 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0344476 |
| GOLGB1 | golgin B1 | 0.033632 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0328162 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0306019 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0300349 |
| RUNX1 | runt-related transcription factor 1 | 0.0300119 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0297322 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0294206 |
| CDK13 | cyclin-dependent kinase 13 | 0.0283046 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0278938 |
| HMGA2 | high mobility group AT-hook 2 | 0.0274153 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.027231 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0269378 |
| EXOC4 | exocyst complex component 4 | 0.0266909 |
| VEGFC | vascular endothelial growth factor C | 0.0261125 |
| FLNA | filamin A, alpha | 0.0260754 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0258973 |
| NBAS | neuroblastoma amplified sequence | 0.0258567 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0254904 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0252998 |
| USP34 | ubiquitin specific peptidase 34 | 0.0252256 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0250703 |
| PRELID2 | PRELI domain containing 2 | 0.0250256 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0247026 |
| NDRG1 | N-myc downstream regulated 1 | 0.0244031 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.0238798 |
| MYLK | myosin light chain kinase | 0.0238696 |
| MSN | moesin | 0.0237912 |
| SMAD3 | SMAD family member 3 | 0.023716 |
| ZNF638 | zinc finger protein 638 | 0.022981 |
| RAI14 | retinoic acid induced 14 | 0.0225917 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0225739 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0225671 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0224445 |
| RNF216 | ring finger protein 216 | 0.0222595 |
| GLIS3 | GLIS family zinc finger 3 | 0.0222143 |
| MYO10 | myosin X | 0.0221057 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0217919 |
| PLEC | plectin | 0.0215961 |
| SMYD3 | SET and MYND domain containing 3 | 0.0215274 |
| FNIP1 | folliculin interacting protein 1 | 0.0215199 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0214598 |
| HYOU1 | hypoxia up-regulated 1 | 0.0213915 |
| RIN2 | Ras and Rab interactor 2 | 0.0213742 |
| CANX | calnexin | 0.0213067 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0209259 |
| STC2 | stanniocalcin 2 | 0.0207749 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | 0.020678 |
| ZNF395 | zinc finger protein 395 | 0.0204348 |
| WNT5A | wingless-type MMTV integration site family, member 5A | 0.0201778 |
| SIL1 | SIL1 nucleotide exchange factor | 0.020102 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0200371 |
| RNF213 | ring finger protein 213 | 0.0200265 |
| ANXA5 | annexin A5 | 0.0199796 |
| PDXDC1 | pyridoxal-dependent decarboxylase domain containing 1 | 0.0197506 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0197246 |
| CADM1 | cell adhesion molecule 1 | 0.019666 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.019639 |
| KYNU | kynureninase | 0.0196129 |
| FRMD4A | FERM domain containing 4A | 0.0195865 |
| NKTR | natural killer cell triggering receptor | 0.0194858 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0193769 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0193533 |
| PRKCA | protein kinase C, alpha | 0.0192456 |
| BPTF | bromodomain PHD finger transcription factor | 0.0191672 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0189175 |
| MMP2 | matrix metallopeptidase 2 | 0.0187981 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0187894 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | 0.0187619 |
| OSMR | oncostatin M receptor | 0.0187575 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0186367 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0185835 |
| CYLD | cylindromatosis (turban tumor syndrome) | 0.0185314 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0183835 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0183628 |
| CLTC | clathrin, heavy chain (Hc) | 0.0183433 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0182971 |
| ATXN1 | ataxin 1 | 0.018213 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.182455 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0938631 |
| MT2A | metallothionein 2A | -0.0922355 |
| COL1A1 | collagen, type I, alpha 1 | -0.0829615 |
| COL1A2 | collagen, type I, alpha 2 | -0.0743632 |
| TMSB10 | thymosin beta 10 | -0.0710541 |
| PTMA | prothymosin, alpha | -0.0649922 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0605644 |
| VIM | vimentin | -0.0471664 |
| CD44 | CD44 molecule (Indian blood group) | -0.044957 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0426385 |
| POTEF | POTE ankyrin domain family, member F | -0.0412576 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0394582 |
| MAP1B | microtubule-associated protein 1B | -0.0361956 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0361116 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0359119 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0354601 |
| CALU | calumenin | -0.033726 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.033245 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | -0.0323465 |
| ANXA2 | annexin A2 | -0.0306443 |
| IGFBP7 | insulin-like growth factor binding protein 7 | -0.0293326 |
| TUBB | tubulin, beta class I | -0.0287494 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0287349 |
| TFG | TRK-fused gene | -0.0282634 |
| RHEB | Ras homolog enriched in brain | -0.0280014 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0278605 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0277953 |
| MT1X | metallothionein 1X | -0.0267782 |
| OGA | O-GlcNAcase | -0.0263267 |
| CCNI | cyclin I | -0.0263235 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0263188 |
| ARF1 | ADP-ribosylation factor 1 | -0.0261276 |
| COL5A2 | collagen, type V, alpha 2 | -0.0259852 |
| HLA-C | major histocompatibility complex, class I, C | -0.0258462 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0258039 |
| THY1 | Thy-1 cell surface antigen | -0.0253039 |
| GNAS | GNAS complex locus | -0.0246344 |
| RPL28 | ribosomal protein L28 | -0.0244176 |
| WASF2 | WAS protein family, member 2 | -0.0237579 |
| CD109 | CD109 molecule | -0.023596 |
| TUBA1B | tubulin, alpha 1b | -0.023471 |
| S100A9 | S100 calcium binding protein A9 | -0.0234514 |
| S100A10 | S100 calcium binding protein A10 | -0.0234013 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0232969 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0229993 |
| HMGB1 | high mobility group box 1 | -0.022862 |
| ZNF217 | zinc finger protein 217 | -0.022682 |
| LOX | lysyl oxidase | -0.0226101 |
| KLHDC10 | kelch domain containing 10 | -0.0226009 |
| SRP54 | signal recognition particle 54kDa | -0.0224509 |
| PRSS23 | protease, serine, 23 | -0.0222536 |
| DIAPH3 | diaphanous-related formin 3 | -0.0221368 |
| TPX2 | TPX2, microtubule-associated | -0.0220849 |
| TXNIP | thioredoxin interacting protein | -0.0219888 |
| MATR3 | matrin 3 | -0.0218508 |
| CD99 | CD99 molecule | -0.0218009 |
| ANLN | anillin, actin binding protein | -0.0214572 |
| SRGN | serglycin | -0.0210365 |
| MKI67 | marker of proliferation Ki-67 | -0.0208183 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0207084 |
| FN1 | fibronectin 1 | -0.0206015 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0204918 |
| ZNF292 | zinc finger protein 292 | -0.0201984 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0200901 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | -0.0198107 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0196942 |
| H3-3B | H3.3 histone B | -0.019691 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | -0.0196675 |
| HLA-A | major histocompatibility complex, class I, A | -0.0194562 |
| RHOA | ras homolog family member A | -0.0194436 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | -0.0193045 |
| CST3 | cystatin C | -0.0190364 |
| YBX3 | Y box binding protein 3 | -0.0190106 |
| PRRC1 | proline-rich coiled-coil 1 | -0.018953 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0188922 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0187815 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0181623 |
| COL3A1 | collagen, type III, alpha 1 | -0.0179118 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | -0.0176043 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0175045 |
| RAP1A | RAP1A, member of RAS oncogene family | -0.0174726 |
| PHF20 | PHD finger protein 20 | -0.0174597 |
| RPS5 | ribosomal protein S5 | -0.0173108 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0171558 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0169038 |
| SEPTIN7 | septin 7 | -0.0168519 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0164918 |
| HBP1 | HMG-box transcription factor 1 | -0.0164238 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0162142 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0161533 |
| CENPF | centromere protein F, 350/400kDa | -0.0160519 |
| HLA-B | major histocompatibility complex, class I, B | -0.0160352 |
| GPBP1 | GC-rich promoter binding protein 1 | -0.0160154 |
| RBM39 | RNA binding motif protein 39 | -0.0159606 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0159156 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.015906 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | -0.0155843 |
| DCTN4 | dynactin 4 (p62) | -0.0153884 |
| BIRC2 | baculoviral IAP repeat containing 2 | -0.0152903 |
