| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ixazomib perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ixazomib_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.117105 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.10793 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0742012 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0658126 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0643708 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0619001 |
| SQSTM1 | sequestosome 1 | 0.057369 |
| CD44 | CD44 molecule (Indian blood group) | 0.0564546 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0545091 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.051566 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0510202 |
| GOLGA4 | golgin A4 | 0.0464025 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0463408 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0448686 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0443131 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0432713 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0413478 |
| ANXA2 | annexin A2 | 0.0411589 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.040908 |
| YBX3 | Y box binding protein 3 | 0.0406616 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0404759 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0388353 |
| SMAD3 | SMAD family member 3 | 0.0375602 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0375356 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0367163 |
| SET | SET nuclear proto-oncogene | 0.035652 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.034689 |
| ZNF292 | zinc finger protein 292 | 0.0343134 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0342104 |
| MSN | moesin | 0.0324011 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.0321909 |
| CWF19L2 | CWF19-like 2, cell cycle control (S. pombe) | 0.0318736 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0318731 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0315117 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0311197 |
| MATR3 | matrin 3 | 0.0308548 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0305907 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0305573 |
| ANXA1 | annexin A1 | 0.0304355 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0299401 |
| RASAL2 | RAS protein activator like 2 | 0.0297519 |
| FUS | FUS RNA binding protein | 0.0296686 |
| CDK6 | cyclin-dependent kinase 6 | 0.0293533 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0293476 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0291721 |
| KIF5B | kinesin family member 5B | 0.0289875 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0286815 |
| FMNL2 | formin-like 2 | 0.0284694 |
| DTNA | dystrobrevin, alpha | 0.0279192 |
| ANO6 | anoctamin 6 | 0.027423 |
| ARRDC3 | arrestin domain containing 3 | 0.0272228 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0268567 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0266555 |
| HELZ | helicase with zinc finger | 0.0266026 |
| GOLGB1 | golgin B1 | 0.0263652 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0263561 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | 0.02631 |
| QKI | QKI, KH domain containing, RNA binding | 0.0261942 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0258866 |
| ACTN1 | actinin, alpha 1 | 0.0257905 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0256005 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0255619 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0255223 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0253318 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0252224 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.025022 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0248466 |
| MYOF | myoferlin | 0.024782 |
| HIPK3 | homeodomain interacting protein kinase 3 | 0.0245478 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.024423 |
| TTC19 | tetratricopeptide repeat domain 19 | 0.0242452 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | 0.023957 |
| CDCP1 | CUB domain containing protein 1 | 0.0238199 |
| ZNF207 | zinc finger protein 207 | 0.0237382 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0235267 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0234019 |
| RNF145 | ring finger protein 145 | 0.0233959 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0233424 |
| NR1D2 | nuclear receptor subfamily 1, group D, member 2 | 0.0231128 |
| CCNL1 | cyclin L1 | 0.0229937 |
| RBM39 | RNA binding motif protein 39 | 0.0229727 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | 0.0227274 |
| TFG | TRK-fused gene | 0.0227072 |
| TXNRD1 | thioredoxin reductase 1 | 0.0226481 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0225003 |
| UBR3 | ubiquitin protein ligase E3 component n-recognin 3 (putative) | 0.0224598 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0224371 |
| PDGFA | platelet-derived growth factor alpha polypeptide | 0.0222374 |
| BSG | basigin (Ok blood group) | 0.0222331 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0219248 |
| ASXL1 | additional sex combs like transcriptional regulator 1 | 0.0218576 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0218247 |
| SPAG9 | sperm associated antigen 9 | 0.0217872 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.021609 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0214874 |
| NUP58 | nucleoporin 58 | 0.0214351 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0214222 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0212041 |
| CD59 | CD59 molecule, complement regulatory protein | 0.021069 |
| PGK1 | phosphoglycerate kinase 1 | 0.0208495 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.104069 |
| VIM | vimentin | -0.0805124 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0781876 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0727224 |
| TMSB10 | thymosin beta 10 | -0.0411673 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0368251 |
| GNAS | GNAS complex locus | -0.0347351 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0342957 |
| HMGA2 | high mobility group AT-hook 2 | -0.0340978 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.0336315 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0334418 |
| IGF2 | insulin-like growth factor 2 | -0.0334074 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0331288 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0329426 |
| RPS23 | ribosomal protein S23 | -0.0320938 |
| AOPEP | aminopeptidase O (putative) | -0.0312486 |
| ST3GAL3 | ST3 beta-galactoside alpha-2,3-sialyltransferase 3 | -0.0311877 |
| VCL | vinculin | -0.0308898 |
| RAI14 | retinoic acid induced 14 | -0.0306302 |
| RPL37A | ribosomal protein L37a | -0.0290611 |
| RPL37 | ribosomal protein L37 | -0.0283069 |
| MAPKAP1 | mitogen-activated protein kinase associated protein 1 | -0.027649 |
| FMN1 | formin 1 | -0.0274207 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0269802 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0269737 |
| RPL15 | ribosomal protein L15 | -0.0268931 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.026882 |
| ZNF609 | zinc finger protein 609 | -0.0267851 |
| CDH4 | cadherin 4, type 1, R-cadherin (retinal) | -0.0261232 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0255325 |
| SRSF9 | serine/arginine-rich splicing factor 9 | -0.025 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0246295 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0245549 |
| ACTG1 | actin gamma 1 | -0.0245109 |
| RPS29 | ribosomal protein S29 | -0.024294 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0239403 |
| HJURP | Holliday junction recognition protein | -0.0239196 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | -0.0239139 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0236287 |
| CELF1 | CUGBP, Elav-like family member 1 | -0.0232939 |
| ERCC6L2 | excision repair cross-complementation group 6-like 2 | -0.023267 |
| TPX2 | TPX2, microtubule-associated | -0.0231707 |
| ETV6 | ets variant 6 | -0.0229746 |
| RPS8 | ribosomal protein S8 | -0.0229417 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | -0.0228574 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0221659 |
| RPS3 | ribosomal protein S3 | -0.0219277 |
| ZMYM4 | zinc finger, MYM-type 4 | -0.0215488 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0214654 |
| CD2AP | CD2-associated protein | -0.02091 |
| APOLD1 | apolipoprotein L domain containing 1 | -0.0208507 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.020815 |
| FN1 | fibronectin 1 | -0.0207822 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0207468 |
| SPDL1 | spindle apparatus coiled-coil protein 1 | -0.0205724 |
| TPST1 | tyrosylprotein sulfotransferase 1 | -0.0205234 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0204478 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0203026 |
| EGR1 | early growth response 1 | -0.0201915 |
| DNER | delta/notch-like EGF repeat containing | -0.0201907 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | -0.0200747 |
| SGO2 | shugoshin 2 | -0.0199635 |
| AGO2 | argonaute RISC catalytic component 2 | -0.0196886 |
| SRPK1 | SRSF protein kinase 1 | -0.0195976 |
| TMEM168 | transmembrane protein 168 | -0.0195198 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.019501 |
| MKI67 | marker of proliferation Ki-67 | -0.0194995 |
| CDK12 | cyclin-dependent kinase 12 | -0.0194841 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0192925 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0192489 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | -0.0192265 |
| PYGL | phosphorylase, glycogen, liver | -0.0192063 |
| CDK13 | cyclin-dependent kinase 13 | -0.0192043 |
| NOL7 | nucleolar protein 7, 27kDa | -0.0192001 |
| CLNS1A | chloride channel, nucleotide-sensitive, 1A | -0.0191864 |
| RPS24 | ribosomal protein S24 | -0.0189896 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | -0.0189351 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0188033 |
| S100A9 | S100 calcium binding protein A9 | -0.018668 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0185557 |
| RPS27A | ribosomal protein S27a | -0.0182508 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0182164 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0181948 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0181548 |
| RPS21 | ribosomal protein S21 | -0.0181069 |
| TRMT11 | tRNA methyltransferase 11 homolog (S. cerevisiae) | -0.0179919 |
| RAI1 | retinoic acid induced 1 | -0.0177747 |
| STK4 | serine/threonine kinase 4 | -0.0177556 |
| TAOK3 | TAO kinase 3 | -0.0177307 |
| KIF4A | kinesin family member 4A | -0.017537 |
| CTBP2 | C-terminal binding protein 2 | -0.0174281 |
| CD63 | CD63 molecule | -0.0172548 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.017023 |
| YEATS2 | YEATS domain containing 2 | -0.0169325 |
| BPTF | bromodomain PHD finger transcription factor | -0.0167844 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | -0.0167791 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0164876 |
| FAM120A | family with sequence similarity 120A | -0.0162333 |
| PARD3 | par-3 family cell polarity regulator | -0.0162212 |
| RPS15 | ribosomal protein S15 | -0.0161375 |
