| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ixazomib perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ixazomib_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HMGA2 | high mobility group AT-hook 2 | 0.186034 |
| FN1 | fibronectin 1 | 0.166537 |
| NRG1 | neuregulin 1 | 0.162499 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.158273 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.10352 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0923644 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0921931 |
| ASPH | aspartate beta-hydroxylase | 0.0908501 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0905801 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0775012 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0753842 |
| TMSB10 | thymosin beta 10 | 0.0742825 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0738138 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0729651 |
| UBC | ubiquitin C | 0.0704452 |
| EFNA5 | ephrin-A5 | 0.0658311 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0657274 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0639737 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0638039 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0634223 |
| VIM | vimentin | 0.0620481 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0597129 |
| RASAL2 | RAS protein activator like 2 | 0.0581722 |
| RAI14 | retinoic acid induced 14 | 0.0581527 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.05615 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0513429 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0507844 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0496282 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0475463 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0474965 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.047252 |
| LOXL2 | lysyl oxidase-like 2 | 0.0470196 |
| TMSB4X | thymosin beta 4, X-linked | 0.0468744 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0462251 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0459934 |
| STC2 | stanniocalcin 2 | 0.0458358 |
| S100A10 | S100 calcium binding protein A10 | 0.0456252 |
| GLIS3 | GLIS family zinc finger 3 | 0.0444372 |
| CANX | calnexin | 0.0442814 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.044133 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0439707 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0437431 |
| MYOF | myoferlin | 0.0431943 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0420519 |
| PTMA | prothymosin, alpha | 0.0417246 |
| IFI44L | interferon-induced protein 44-like | 0.0411177 |
| MCL1 | myeloid cell leukemia 1 | 0.0395658 |
| RNF213 | ring finger protein 213 | 0.0391067 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0390957 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0390115 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0385031 |
| TXNIP | thioredoxin interacting protein | 0.0375135 |
| AHNAK | AHNAK nucleoprotein | 0.0374368 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0372172 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0369821 |
| AGPAT4 | 1-acylglycerol-3-phosphate O-acyltransferase 4 | 0.0362618 |
| MRPS6 | mitochondrial ribosomal protein S6 | 0.0362455 |
| CALR | calreticulin | 0.0352327 |
| S100A6 | S100 calcium binding protein A6 | 0.0344999 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0339927 |
| PLIN2 | perilipin 2 | 0.0334305 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0334153 |
| FLNA | filamin A, alpha | 0.0329356 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0323432 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0319429 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.0318501 |
| LMNA | lamin A/C | 0.0315731 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0315373 |
| LOX | lysyl oxidase | 0.0312952 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0312189 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0310018 |
| SFRP1 | secreted frizzled-related protein 1 | 0.0307339 |
| DUSP6 | dual specificity phosphatase 6 | 0.0299632 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0298833 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0296334 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.0294429 |
| NDRG1 | N-myc downstream regulated 1 | 0.02943 |
| FAT1 | FAT atypical cadherin 1 | 0.0291778 |
| EMP1 | epithelial membrane protein 1 | 0.0290761 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | 0.0289584 |
| TNS3 | tensin 3 | 0.028897 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.0288049 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0288041 |
| OXR1 | oxidation resistance 1 | 0.0285811 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | 0.0285568 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0284655 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.0280838 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0276093 |
| JUN | jun proto-oncogene | 0.0272834 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0271441 |
| MT2A | metallothionein 2A | 0.0271265 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A | 0.0269498 |
| GPATCH2L | G patch domain containing 2-like | 0.0269287 |
| SFTPA2 | surfactant protein A2 | 0.0265945 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0264269 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0262929 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0262792 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0261971 |
| SLC35F3 | solute carrier family 35, member F3 | 0.0258936 |
| RFX2 | regulatory factor X, 2 (influences HLA class II expression) | 0.0258884 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FTL | ferritin, light polypeptide | -0.101231 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0980972 |
| CENPF | centromere protein F, 350/400kDa | -0.0919627 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0741374 |
| RPS6 | ribosomal protein S6 | -0.0547457 |
| RPL11 | ribosomal protein L11 | -0.0472129 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0460161 |
| RPS12 | ribosomal protein S12 | -0.0459118 |
| RBM39 | RNA binding motif protein 39 | -0.045834 |
| RPL37A | ribosomal protein L37a | -0.0432767 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.039343 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.0382439 |
| RNF145 | ring finger protein 145 | -0.0371727 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.036862 |
| SQSTM1 | sequestosome 1 | -0.0361407 |
| RPS8 | ribosomal protein S8 | -0.0351517 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0346681 |
| RPL9 | ribosomal protein L9 | -0.0345915 |
| MKI67 | marker of proliferation Ki-67 | -0.0340007 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0338302 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.033295 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0330668 |
| RPS2 | ribosomal protein S2 | -0.0330333 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0330131 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0329917 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0328471 |
| RPS3 | ribosomal protein S3 | -0.0325167 |
| RPL38 | ribosomal protein L38 | -0.0317183 |
| AHR | aryl hydrocarbon receptor | -0.0316244 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0313973 |
| NEK7 | NIMA-related kinase 7 | -0.0309084 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0304895 |
| RACK1 | receptor for activated C kinase 1 | -0.029654 |
| RPL35A | ribosomal protein L35a | -0.0291747 |
| OGA | O-GlcNAcase | -0.029084 |
| RPL12 | ribosomal protein L12 | -0.0289462 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0281075 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | -0.0277822 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.027162 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | -0.0270757 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0266542 |
| ADD3 | adducin 3 (gamma) | -0.0263088 |
| RPL26 | ribosomal protein L26 | -0.0259696 |
| SMOX | spermine oxidase | -0.0258367 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0257881 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0257741 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0256848 |
| ETNK1 | ethanolamine kinase 1 | -0.0249421 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.0249028 |
| TENT2 | terminal nucleotidyltransferase 2 | -0.0244883 |
| ANLN | anillin, actin binding protein | -0.0242856 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0239636 |
| SMIM14 | small integral membrane protein 14 | -0.0235493 |
| GOLT1B | golgi transport 1B | -0.0229548 |
| MTDH | metadherin | -0.0227226 |
| APOLD1 | apolipoprotein L domain containing 1 | -0.0227105 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.022184 |
| UBXN4 | UBX domain protein 4 | -0.0221146 |
| FBXL5 | F-box and leucine-rich repeat protein 5 | -0.0213191 |
| FAM168B | family with sequence similarity 168, member B | -0.0210623 |
| KIF5B | kinesin family member 5B | -0.0208605 |
| RPL19 | ribosomal protein L19 | -0.0206723 |
| CKAP2 | cytoskeleton associated protein 2 | -0.0204851 |
| DUSP5 | dual specificity phosphatase 5 | -0.0202096 |
| RPS23 | ribosomal protein S23 | -0.019841 |
| FNBP1 | formin binding protein 1 | -0.0198302 |
| HMGB3 | high mobility group box 3 | -0.0198198 |
| RPS16 | ribosomal protein S16 | -0.0196803 |
| BOD1L1 | biorientation of chromosomes in cell division 1-like 1 | -0.0196566 |
| FAF2 | Fas associated factor family member 2 | -0.0196443 |
| TNPO3 | transportin 3 | -0.0195727 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | -0.0195267 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0194154 |
| TMEM39A | transmembrane protein 39A | -0.0193587 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | -0.0193212 |
| RAB8B | RAB8B, member RAS oncogene family | -0.0192398 |
| FOXP1 | forkhead box P1 | -0.0191709 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0190908 |
| TXNRD1 | thioredoxin reductase 1 | -0.01873 |
| ARID4A | AT rich interactive domain 4A (RBP1-like) | -0.0185432 |
| RPS29 | ribosomal protein S29 | -0.0184801 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -0.0182689 |
| PCDH7 | protocadherin 7 | -0.0181794 |
| RO60 | Ro60, Y RNA binding protein | -0.0181713 |
| RPS27 | ribosomal protein S27 | -0.0181576 |
| RPL7 | ribosomal protein L7 | -0.0181295 |
| XPO1 | exportin 1 | -0.0180246 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.0179806 |
| CLTC | clathrin, heavy chain (Hc) | -0.0177833 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0177482 |
| RPL18 | ribosomal protein L18 | -0.0176845 |
| RPL31 | ribosomal protein L31 | -0.0175026 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0172831 |
| SH3GLB1 | SH3-domain GRB2-like endophilin B1 | -0.0172395 |
| PELO | pelota homolog (Drosophila) | -0.0170992 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | -0.0170416 |
| RPL5 | ribosomal protein L5 | -0.0170153 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | -0.0169552 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0168355 |
| BUB1 | BUB1 mitotic checkpoint serine/threonine kinase | -0.0167907 |
