JAK2 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description Janus kinase 2|This gene product is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 3717)
External Link https://ncbi.nlm.nih.gov/gene/3717
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Genes

498 genes differentially expressed following the JAK2 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
XIC X chromosome inactivation center 0.030104
HSPB1 heat shock 27kDa protein 1 0.0130776
MMP1 matrix metallopeptidase 1 0.0118544
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) 0.0113548
MT1E metallothionein 1E 0.0111317
RRAGA Ras-related GTP binding A 0.0103515
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 0.0102918
BASP1 brain abundant, membrane attached signal protein 1 0.0101633
POU2AF1 POU class 2 associating factor 1 0.00995983
MT1H metallothionein 1H 0.00965246
TFPI2 tissue factor pathway inhibitor 2 0.00943025
HTRA1 HtrA serine peptidase 1 0.00908153
MT1X metallothionein 1X 0.00902491
PLIN2 perilipin 2 0.00887848
PTK2B protein tyrosine kinase 2 beta 0.00882287
SLC38A1 solute carrier family 38, member 1 0.00880098
PEG10 paternally expressed 10 0.00859236
SCGB2A1 secretoglobin, family 2A, member 1 0.00853042
GABRP gamma-aminobutyric acid (GABA) A receptor, pi 0.00850843
MT1G metallothionein 1G 0.00848397
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae) 0.00818678
ACAA2 acetyl-CoA acyltransferase 2 0.00816459
PITX3 paired-like homeodomain 3 0.00816053
CD79A CD79a molecule, immunoglobulin-associated alpha 0.00805697
MT1HL1 metallothionein 1H-like 1 0.00801447
HK2 hexokinase 2 0.00793201
CTSD cathepsin D 0.00782973
TMEM158 transmembrane protein 158 (gene/pseudogene) 0.00780466
CRABP2 cellular retinoic acid binding protein 2 0.00767806
VTCN1 V-set domain containing T cell activation inhibitor 1 0.00760022
OLFM4 olfactomedin 4 0.00744754
PAX5 paired box 5 0.00741169
AOC1 amine oxidase, copper containing 1 0.00739762
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) 0.0073813
CEMIP cell migration inducing protein, hyaluronan binding 0.00728337
MT1F metallothionein 1F 0.00715982
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 0.00710384
DEFA4 defensin, alpha 4, corticostatin 0.00700043
ZNF91 zinc finger protein 91 0.00697361
H1-10 H1.10 linker histone 0.00687777
BAMBI BMP and activin membrane-bound inhibitor 0.00682692
MMP9 matrix metallopeptidase 9 0.00680056
SNAI2 snail family zinc finger 2 0.00672623
ADD3 adducin 3 (gamma) 0.00662006
CLDN3 claudin 3 0.00657865
RND3 Rho family GTPase 3 0.0063594
NOTCH1 notch 1 0.0063449
WDR7 WD repeat domain 7 0.00633785
RBM34 RNA binding motif protein 34 0.00632288
MZB1 marginal zone B and B1 cell-specific protein 0.0063044
CD19 CD19 molecule 0.00628737
MT2A metallothionein 2A 0.00625916
SCGB1D2 secretoglobin, family 1D, member 2 0.00625693
ECM1 extracellular matrix protein 1 0.00623604
S100A8 S100 calcium binding protein A8 0.00623434
HIST1H2BD histone cluster 1, H2bd 0.00623156
ADM adrenomedullin 0.0062185
NDRG1 N-myc downstream regulated 1 0.00611816
CALB1 calbindin 1, 28kDa 0.00587506
CCNA2 cyclin A2 0.00585712
JCHAIN joining chain of multimeric IgA and IgM 0.00585331
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5 0.00585018
BTF3P11 basic transcription factor 3 pseudogene 11 0.00584635
GADD45A growth arrest and DNA-damage-inducible, alpha 0.00584181
MAGEA3 melanoma antigen family A3 0.00582786
HMOX1 heme oxygenase 1 0.0058175
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1 0.00574341
XYLT1 xylosyltransferase I 0.00571406
MARCKS myristoylated alanine-rich protein kinase C substrate 0.00571388
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 0.00569237
MAMLD1 mastermind-like domain containing 1 0.00568647
GJA1 gap junction protein, alpha 1, 43kDa 0.00568341
BLNK B-cell linker 0.00567735
TNFRSF17 tumor necrosis factor receptor superfamily, member 17 0.00566713
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1 0.00563098
KDM5C lysine (K)-specific demethylase 5C 0.00562562
CD79B CD79b molecule, immunoglobulin-associated beta 0.0056007
TGFB1 transforming growth factor, beta 1 0.0055825
MINK1 misshapen-like kinase 1 0.0055809
SWAP70 SWAP switching B-cell complex 70kDa subunit 0.00551994
TMEM176A transmembrane protein 176A 0.0055178
ATP2A3 ATPase, Ca++ transporting, ubiquitous 0.00548357
MOK MOK protein kinase 0.00544966
PRKX protein kinase, X-linked 0.00544071
TCL1A T-cell leukemia/lymphoma 1A 0.00542371
COL9A2 collagen, type IX, alpha 2 0.00539707
CX3CL1 chemokine (C-X3-C motif) ligand 1 0.00537529
VPREB3 pre-B lymphocyte 3 0.00537241
CDKN2A cyclin-dependent kinase inhibitor 2A 0.00534692
KANK1 KN motif and ankyrin repeat domains 1 0.00531193
RGS16 regulator of G-protein signaling 16 0.00526675
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1 0.00523856
FOLR1 folate receptor 1 (adult) 0.00523097
SCG5 secretogranin V 0.00522292
INA internexin neuronal intermediate filament protein, alpha 0.00520972
CD9 CD9 molecule 0.00518166
ZG16 zymogen granule protein 16 0.00518142
OSBPL10 oxysterol binding protein-like 10 0.00516844
MUC2 mucin 2, oligomeric mucus/gel-forming 0.00516307
SMAD7 SMAD family member 7 0.00515876
PLS3 plastin 3 0.00508931
CLCN7 chloride channel, voltage-sensitive 7 0.00508358
CTNND1 catenin (cadherin-associated protein), delta 1 0.0050692
EFHD1 EF-hand domain family, member D1 0.00504014
CD44 CD44 molecule (Indian blood group) 0.0050367
RFTN1 raftlin, lipid raft linker 1 0.00501832
CXCL13 chemokine (C-X-C motif) ligand 13 0.00501317
ZNF580 zinc finger protein 580 0.00500941
HOMER3 homer scaffolding protein 3 0.00496369
CDH17 cadherin 17, LI cadherin (liver-intestine) 0.0049394
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 0.00493406
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) 0.00493383
IPO13 importin 13 0.00492392
AURKB aurora kinase B 0.00490704
PBLD phenazine biosynthesis-like protein domain containing 0.00489647
SGCE sarcoglycan, epsilon 0.00489285
AMOTL2 angiomotin like 2 0.00488585
SCN3A sodium channel, voltage gated, type III alpha subunit 0.0048854
STC2 stanniocalcin 2 0.00487648
UGT8 UDP glycosyltransferase 8 0.00486567
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6 0.0048646
KDM6A lysine (K)-specific demethylase 6A 0.00485139
EXT1 exostosin glycosyltransferase 1 0.00484721
MS4A1 membrane-spanning 4-domains, subfamily A, member 1 0.0048442
RGS4 regulator of G-protein signaling 4 0.00482205
CD72 CD72 molecule 0.00478535
NECTIN3 nectin cell adhesion molecule 3 0.00476125
CEACAM7 carcinoembryonic antigen-related cell adhesion molecule 7 0.00472939
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1 0.00471923
MBD2 methyl-CpG binding domain protein 2 0.00470516
MAP1LC3B microtubule-associated protein 1 light chain 3 beta 0.00470407
ASS1 argininosuccinate synthase 1 0.0047005
SCPEP1 serine carboxypeptidase 1 0.00466632
NDUFS7 NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase) 0.00465959
PLK1 polo-like kinase 1 0.00464946
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding) 0.00464261
KRT17 keratin 17, type I 0.00463834
PLXNA1 plexin A1 0.00463794
SPINK1 serine peptidase inhibitor, Kazal type 1 0.00463238
FZD2 frizzled class receptor 2 0.00462354
ANGPTL4 angiopoietin-like 4 0.00462113
HIP1R huntingtin interacting protein 1 related 0.00461111
CNOT3 CCR4-NOT transcription complex, subunit 3 0.00459855
SPINK4 serine peptidase inhibitor, Kazal type 4 0.00459764
VAC14 Vac14 homolog (S. cerevisiae) 0.00459323
WNT5B wingless-type MMTV integration site family, member 5B 0.00456998
CD22 CD22 molecule 0.00456764
IER5 immediate early response 5 0.00455732
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 0.00454967
ACTN4 actinin, alpha 4 0.004547
DGKZ diacylglycerol kinase, zeta 0.00454044
SLC39A8 solute carrier family 39 (zinc transporter), member 8 0.00453368
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5 0.00453317
TPBG trophoblast glycoprotein 0.00453303
COL6A3 collagen, type VI, alpha 3 0.00453208
POSTN periostin, osteoblast specific factor 0.00452236
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble 0.00451473
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 0.0045127
CLIC3 chloride intracellular channel 3 0.00451061
PALM paralemmin 0.00447911
SMC1A structural maintenance of chromosomes 1A 0.00447538
PCSK1 proprotein convertase subtilisin/kexin type 1 0.00445494
NOX1 NADPH oxidase 1 0.00444897
HSF1 heat shock transcription factor 1 0.00444634
SF3A2 splicing factor 3a, subunit 2, 66kDa 0.00443921
CAMP cathelicidin antimicrobial peptide 0.0044378
SGK1 serum/glucocorticoid regulated kinase 1 0.00442952
TSPAN12 tetraspanin 12 0.00442761
KCNK12 potassium channel, two pore domain subfamily K, member 12 0.00440588
RRBP1 ribosome binding protein 1 0.00439928
HSPA1A heat shock 70kDa protein 1A 0.00439098
SOCS2 suppressor of cytokine signaling 2 0.00437846
FSD1 fibronectin type III and SPRY domain containing 1 0.00436957
CCNG2 cyclin G2 0.0043679
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A 0.00434809
LGALS4 lectin, galactoside-binding, soluble, 4 0.00433812
CRABP1 cellular retinoic acid binding protein 1 0.00432787
IGFBP4 insulin-like growth factor binding protein 4 0.00431483
PDLIM1 PDZ and LIM domain 1 0.00430881
PIGR polymeric immunoglobulin receptor 0.00430421
RCAN1 regulator of calcineurin 1 0.00429973
ALAS1 5'-aminolevulinate synthase 1 0.00429281
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 0.00427772
LEFTY1 left-right determination factor 1 0.0042759
DEF8 differentially expressed in FDCP 8 homolog (mouse) 0.00426704
NCF1C neutrophil cytosolic factor 1C pseudogene 0.00425601
CLIP2 CAP-GLY domain containing linker protein 2 0.00425522
BMP2 bone morphogenetic protein 2 0.00425511
ABHD17A abhydrolase domain containing 17A 0.00424719
PXDC1 PX domain containing 1 0.0042368
CA12 carbonic anhydrase XII 0.00422944
CEACAM8 carcinoembryonic antigen-related cell adhesion molecule 8 0.00419711
PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor 0.00419332
BCL7A B-cell CLL/lymphoma 7A 0.00417918
GRINA glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding) 0.00417454
CLASRP CLK4-associating serine/arginine rich protein 0.00417428
FXYD5 FXYD domain containing ion transport regulator 5 0.00416255
UPP1 uridine phosphorylase 1 0.00416152
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 0.00415935
BTG1 B-cell translocation gene 1, anti-proliferative 0.00414894
CEBPG CCAAT/enhancer binding protein (C/EBP), gamma 0.00412893
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3 0.00412641
CAPG capping protein (actin filament), gelsolin-like 0.0041195
PRRC2A proline-rich coiled-coil 2A 0.00411639
SPIB Spi-B transcription factor (Spi-1/PU.1 related) 0.00410979
ZIC1 Zic family member 1 0.00410629
EN1 engrailed homeobox 1 0.00410135
ARL4C ADP-ribosylation factor-like 4C 0.00409677
HSPA6 heat shock 70kDa protein 6 (HSP70B') 0.00408508
DSP desmoplakin 0.00408168
MYB v-myb avian myeloblastosis viral oncogene homolog 0.00406823
EXOSC4 exosome component 4 0.00406708
PARM1 prostate androgen-regulated mucin-like protein 1 0.00405913
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2 0.00405696
GNAS GNAS complex locus 0.00405176
MAGEA12 melanoma antigen family A12 0.00404671
DDAH1 dimethylarginine dimethylaminohydrolase 1 0.00404568
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2 0.00404181
SH2B2 SH2B adaptor protein 2 0.00403534
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2 0.00403501
TP53I3 tumor protein p53 inducible protein 3 0.00403446
TMEM243 transmembrane protein 243, mitochondrial 0.00403037
REG1A regenerating islet-derived 1 alpha 0.0040238
NPTX1 neuronal pentraxin I 0.00401806
IRAG2 inositol 1,4,5-triphosphate receptor associated 2 0.00401262
TCTA T-cell leukemia translocation altered 0.00401112
TENT4A terminal nucleotidyltransferase 4A 0.00399569
GSTA1 glutathione S-transferase alpha 1 0.0039846
TCF7L1 transcription factor 7-like 1 (T-cell specific, HMG-box) 0.00397372
ITGB7 integrin, beta 7 0.00394699
NRXN2 neurexin 2 0.00394569
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 0.00393907
SHB Src homology 2 domain containing adaptor protein B 0.00393634
ARHGAP22 Rho GTPase activating protein 22 0.00393131
SNX7 sorting nexin 7 0.0039289
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1) 0.003923
FABP1 fatty acid binding protein 1, liver 0.00391626
LRRC19 leucine rich repeat containing 19 0.00391159
ARMCX2 armadillo repeat containing, X-linked 2 0.00390664
TMEM176B transmembrane protein 176B 0.00390186
RRAGC Ras-related GTP binding C 0.00389987
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble) 0.00389783
AP3D1 adaptor-related protein complex 3, delta 1 subunit 0.00388759
SAFB scaffold attachment factor B 0.00388688
MAP7 microtubule-associated protein 7 0.00388383
HYOU1 hypoxia up-regulated 1 0.00388129
WASL Wiskott-Aldrich syndrome-like 0.00387126
EDN1 endothelin 1 0.0038679

decreased expression

Symbol Name Standardized Value
RPS4Y1 ribosomal protein S4, Y-linked 1 -0.0310416
EIF1AY eukaryotic translation initiation factor 1A, Y-linked -0.0216869
KDM5D lysine (K)-specific demethylase 5D -0.0203073
AKAP8 A kinase (PRKA) anchor protein 8 -0.0127844
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked -0.0117018
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -0.00941625
ALDH1A3 aldehyde dehydrogenase 1 family, member A3 -0.00911123
LY6D lymphocyte antigen 6 complex, locus D -0.00880393
RGCC regulator of cell cycle -0.00877703
SORBS1 sorbin and SH3 domain containing 1 -0.00871777
ANOS1 anosmin 1 -0.00867808
ADO 2-aminoethanethiol (cysteamine) dioxygenase -0.00864289
CD99 CD99 molecule -0.00860052
CHRDL1 chordin-like 1 -0.00856758
DES desmin -0.00850355
CTSH cathepsin H -0.00827706
CFH complement factor H -0.00823089
PLN phospholamban -0.0081315
MYBPC1 myosin binding protein C, slow type -0.00796588
SYNM synemin, intermediate filament protein -0.00788513
ALDH3A1 aldehyde dehydrogenase 3 family, member A1 -0.00778224
C1S complement component 1, s subcomponent -0.00774816
NIBAN1 niban apoptosis regulator 1 -0.0077432
CD93 CD93 molecule -0.00742981
PGC progastricsin (pepsinogen C) -0.00731672
MOXD1 monooxygenase, DBH-like 1 -0.00731244
ACTG2 actin, gamma 2, smooth muscle, enteric -0.00715393
ARID4A AT rich interactive domain 4A (RBP1-like) -0.00710833
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 -0.00709644
SPARCL1 SPARC-like 1 (hevin) -0.00707649
COQ8A coenzyme Q8A -0.00705301
CNPY3 canopy FGF signaling regulator 3 -0.00701513
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2 -0.00697126
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 -0.00692761
PDE4B phosphodiesterase 4B, cAMP-specific -0.00690366
GPX3 glutathione peroxidase 3 -0.00687753
TSPAN8 tetraspanin 8 -0.0066918
STOM stomatin -0.00665642
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 -0.00659511
HOPX HOP homeobox -0.0065889
A2M alpha-2-macroglobulin -0.00658877
RAMP1 receptor (G protein-coupled) activity modifying protein 1 -0.00656391
MYH11 myosin, heavy chain 11, smooth muscle -0.00656031
SPP1 secreted phosphoprotein 1 -0.00652613
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase) -0.00646641
PTGIS prostaglandin I2 (prostacyclin) synthase -0.00645812
FBLN1 fibulin 1 -0.00644926
LAMA4 laminin, alpha 4 -0.00643501
HSPB8 heat shock 22kDa protein 8 -0.00638455
EGR3 early growth response 3 -0.00633659
AKAP12 A kinase (PRKA) anchor protein 12 -0.00632251
SERPINB6 serpin peptidase inhibitor, clade B (ovalbumin), member 6 -0.00630786
RARRES1 retinoic acid receptor responder (tazarotene induced) 1 -0.00630361
IFI44L interferon-induced protein 44-like -0.0062613
GPR183 G protein-coupled receptor 183 -0.00622411
PER2 period circadian clock 2 -0.00621207
CLU clusterin -0.00618424
WWTR1 WW domain containing transcription regulator 1 -0.00618135
MX1 MX dynamin-like GTPase 1 -0.00614991
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9 -0.00610249
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) -0.00607281
SPRED2 sprouty-related, EVH1 domain containing 2 -0.00601581
EGR2 early growth response 2 -0.00600425
TPM2 tropomyosin 2 (beta) -0.00600076
SYBU syntabulin (syntaxin-interacting) -0.00598063
EEF1A2 eukaryotic translation elongation factor 1 alpha 2 -0.00594838
AHR aryl hydrocarbon receptor -0.00593526
HOMER2 homer scaffolding protein 2 -0.00591073
VCAN versican -0.00589424
C1R complement component 1, r subcomponent -0.00588836
MXRA5 matrix-remodelling associated 5 -0.0058827
RAPSN receptor-associated protein of the synapse -0.00587152
SVIL supervillin -0.00586614
USP9Y ubiquitin specific peptidase 9, Y-linked -0.00586275
SPARC secreted protein, acidic, cysteine-rich (osteonectin) -0.00585486
ITM2A integral membrane protein 2A -0.00583562
MLF1 myeloid leukemia factor 1 -0.00579638
DEGS1 delta(4)-desaturase, sphingolipid 1 -0.00579458
TGM2 transglutaminase 2 -0.00579234
BAG2 BCL2-associated athanogene 2 -0.00578953
ASPN asporin -0.00575662
MX2 MX dynamin-like GTPase 2 -0.00575483
MSMB microseminoprotein, beta- -0.00573978
COL15A1 collagen, type XV, alpha 1 -0.00569132
NID1 nidogen 1 -0.00566091
MOCOS molybdenum cofactor sulfurase -0.00564809
PMP22 peripheral myelin protein 22 -0.00557137
MGP matrix Gla protein -0.00556692
ZBTB18 zinc finger and BTB domain containing 18 -0.00556608
XPO7 exportin 7 -0.00551277
SIK1 salt-inducible kinase 1 -0.00545166
GSTT1 glutathione S-transferase theta 1 -0.0054476
NHS Nance-Horan syndrome (congenital cataracts and dental anomalies) -0.00543732
LAMP2 lysosomal-associated membrane protein 2 -0.0053801
NIPSNAP2 nipsnap homolog 2 -0.00537518
SELENOW selenoprotein W -0.00536895
PCGF2 polycomb group ring finger 2 -0.00536674
DHRS3 dehydrogenase/reductase (SDR family) member 3 -0.00533454
PER3 period circadian clock 3 -0.0053163
NR4A2 nuclear receptor subfamily 4, group A, member 2 -0.0053063
DEFB1 defensin, beta 1 -0.00528299
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32) -0.00526526
PER1 period circadian clock 1 -0.00524958
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) -0.00524565
TTN titin -0.00521641
GSTA4 glutathione S-transferase alpha 4 -0.00520391
ALDH1A2 aldehyde dehydrogenase 1 family, member A2 -0.00519707
PALMD palmdelphin -0.00519477
IRS2 insulin receptor substrate 2 -0.0051783
CALML5 calmodulin-like 5 -0.00517697
BST2 bone marrow stromal cell antigen 2 -0.00517511
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog -0.00517389
SLURP1 secreted LY6/PLAUR domain containing 1 -0.00513519
COL21A1 collagen, type XXI, alpha 1 -0.00511677
KIAA0232 KIAA0232 -0.00510315
NCAPD3 non-SMC condensin II complex, subunit D3 -0.00509444
CD14 CD14 molecule -0.00507769
PCTP phosphatidylcholine transfer protein -0.00507076
TXLNA taxilin alpha -0.00506707
PCSK5 proprotein convertase subtilisin/kexin type 5 -0.00505473
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) -0.00504269
STAT5B signal transducer and activator of transcription 5B -0.00503995
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) -0.00503772
ACACA acetyl-CoA carboxylase alpha -0.00501506
F13A1 coagulation factor XIII, A1 polypeptide -0.00500072
TTTY15 testis-specific transcript, Y-linked 15 (non-protein coding) -0.00500052
MB myoglobin -0.00500007
MFAP4 microfibrillar-associated protein 4 -0.00499287
MAOB monoamine oxidase B -0.00498993
KLHL23 kelch-like family member 23 -0.00498625
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) -0.0049849
NPL N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase) -0.00496316
TBL1X transducin (beta)-like 1X-linked -0.00496232
SGMS1 sphingomyelin synthase 1 -0.00494529
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32) -0.00494198
RAB4A RAB4A, member RAS oncogene family -0.00493451
SFN stratifin -0.00493149
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4 -0.00491955
RARRES2 retinoic acid receptor responder (tazarotene induced) 2 -0.00489707
SNX10 sorting nexin 10 -0.00486579
CRIP1 cysteine-rich protein 1 (intestinal) -0.00486541
NKX3-1 NK3 homeobox 1 -0.00486319
RBBP4 retinoblastoma binding protein 4 -0.00485989
TMEM204 transmembrane protein 204 -0.00482054
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila) -0.00481419
C3 complement component 3 -0.00481198
KANK2 KN motif and ankyrin repeat domains 2 -0.00480127
CDK6 cyclin-dependent kinase 6 -0.00478862
COL4A5 collagen, type IV, alpha 5 -0.00478089
TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa -0.00477743
LAMC1 laminin, gamma 1 (formerly LAMB2) -0.00476451
DMAC2L distal membrane arm assembly component 2 like -0.00475723
ZSCAN31 zinc finger and SCAN domain containing 31 -0.00475537
OLFM1 olfactomedin 1 -0.00475025
ELOVL5 ELOVL fatty acid elongase 5 -0.00471988
PTGES prostaglandin E synthase -0.00470307
BCHE butyrylcholinesterase -0.00467041
PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1 -0.00466475
GPC3 glypican 3 -0.00466053
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3 -0.00463947
PTN pleiotrophin -0.00463557
CES1 carboxylesterase 1 -0.00462058
FBXO11 F-box protein 11 -0.00460216
TMEM255A transmembrane protein 255A -0.00459757
GIMAP4 GTPase, IMAP family member 4 -0.0045934
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2 -0.00459112
PGD phosphogluconate dehydrogenase -0.00458539
YBX3 Y box binding protein 3 -0.00458269
TP73-AS1 TP73 antisense RNA 1 -0.00457578
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) -0.00456792
RLN1 relaxin 1 -0.00456593
TPPP3 tubulin polymerization-promoting protein family member 3 -0.00455798
HAL histidine ammonia-lyase -0.0045553
TPM3 tropomyosin 3 -0.00454975
PDLIM3 PDZ and LIM domain 3 -0.00454331
PLAT plasminogen activator, tissue -0.00453521
ACP3 acid phosphatase 3 -0.00452211
ASH2L ash2 (absent, small, or homeotic)-like (Drosophila) -0.00452115
SFTPB surfactant protein B -0.00450556
SACS sacsin molecular chaperone -0.00449782
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A -0.00448852
ECI2 enoyl-CoA delta isomerase 2 -0.00448294
ZEB1 zinc finger E-box binding homeobox 1 -0.00445781
ACTA2 actin, alpha 2, smooth muscle, aorta -0.0044472
PIP prolactin-induced protein -0.00441831
MYH2 myosin, heavy chain 2, skeletal muscle, adult -0.00441791
PDGFRL platelet-derived growth factor receptor-like -0.00441196
MS4A4A membrane-spanning 4-domains, subfamily A, member 4A -0.00438932
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide -0.00438122
METRN meteorin, glial cell differentiation regulator -0.00437483
RGS5 regulator of G-protein signaling 5 -0.0043747
LIMCH1 LIM and calponin homology domains 1 -0.00436775
SPON1 spondin 1, extracellular matrix protein -0.00435242
RASSF2 Ras association (RalGDS/AF-6) domain family member 2 -0.0043419
LAGE3 L antigen family, member 3 -0.00433977
AGTPBP1 ATP/GTP binding protein 1 -0.00433351
FADS1 fatty acid desaturase 1 -0.00433157
ASPH aspartate beta-hydroxylase -0.00431051
FYB1 FYN binding protein 1 -0.00430934
SEPP1 selenoprotein P, plasma, 1 -0.00429559
COPS7A COP9 signalosome subunit 7A -0.00428845
TMEM100 transmembrane protein 100 -0.00428268
CD302 CD302 molecule -0.00428237
SMPX small muscle protein, X-linked -0.00427653
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 -0.00427591
GSR glutathione reductase -0.00427366
SPON2 spondin 2, extracellular matrix protein -0.00426439
DCTN4 dynactin 4 (p62) -0.00426423
TNNC2 troponin C type 2 (fast) -0.00426417
FEZ1 fasciculation and elongation protein zeta 1 (zygin I) -0.00425961
CH25H cholesterol 25-hydroxylase -0.00425324
DMXL1 Dmx-like 1 -0.0042515
CD46 CD46 molecule, complement regulatory protein -0.00424255
LPP LIM domain containing preferred translocation partner in lipoma -0.00423761
HOXA5 homeobox A5 -0.00422081
CNN1 calponin 1, basic, smooth muscle -0.00422079
WSB2 WD repeat and SOCS box containing 2 -0.00422053
COL4A6 collagen, type IV, alpha 6 -0.00421855
TMX4 thioredoxin-related transmembrane protein 4 -0.00421246
ACSL1 acyl-CoA synthetase long-chain family member 1 -0.00421204
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1 -0.00421171
SHTN1 shootin 1 -0.0041955
AOC3 amine oxidase, copper containing 3 -0.00419389
ULK2 unc-51 like autophagy activating kinase 2 -0.00418978
FOSL2 FOS-like antigen 2 -0.00417057
RXYLT1 ribitol xylosyltransferase 1 -0.00416984
ENSA endosulfine alpha -0.00416796
CHEK2 checkpoint kinase 2 -0.00416454
SLIT2 slit homolog 2 (Drosophila) -0.0041636
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 -0.0041609
C1QTNF3 C1q and tumor necrosis factor related protein 3 -0.00414756
MYL1 myosin, light chain 1, alkali; skeletal, fast -0.00414214
DPYSL3 dihydropyrimidinase-like 3 -0.00413288
COL14A1 collagen, type XIV, alpha 1 -0.00412916
TMC5 transmembrane channel-like 5 -0.00412365
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa -0.00412129
TYRP1 tyrosinase-related protein 1 -0.00412053
KLK8 kallikrein-related peptidase 8 -0.00410933
CCL13 chemokine (C-C motif) ligand 13 -0.00410925
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide -0.00410805
CEL carboxyl ester lipase -0.00409963
GIMAP5 GTPase, IMAP family member 5 -0.004098
COLEC12 collectin sub-family member 12 -0.00408823
CDH5 cadherin 5, type 2 (vascular endothelium) -0.00408402
KAT7 K(lysine) acetyltransferase 7 -0.00408177
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) -0.00407639
TGFBI transforming growth factor, beta-induced, 68kDa -0.00406738
CD2 CD2 molecule -0.00406494
APOC2 apolipoprotein C-II -0.00406099
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein) -0.00405403