JAK2 Gene Set

Dataset PhosphoSitePlus Substrates of Kinases
Category physical interactions
Type kinase
Description Janus kinase 2|This gene product is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 3717)
External Link http://www.ncbi.nlm.nih.gov/gene/3717
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Genes

25 substrates of the kinase JAK2 from the curated PhosphoSitePlus Substrates of Kinases dataset.

Symbol Name
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
CCR2 chemokine (C-C motif) receptor 2
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CTLA4 cytotoxic T-lymphocyte-associated protein 4
EPOR erythropoietin receptor
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
GAB2 GRB2-associated binding protein 2
GRB2 growth factor receptor-bound protein 2
GTF2I general transcription factor IIi
HIST1H3A histone cluster 1, H3a
JAK2 Janus kinase 2
MAP3K5 mitogen-activated protein kinase kinase kinase 5
MAPK1 mitogen-activated protein kinase 1
MAPK3 mitogen-activated protein kinase 3
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PRLR prolactin receptor
PRMT5 protein arginine methyltransferase 5
PTPN11 protein tyrosine phosphatase, non-receptor type 11
SOCS3 suppressor of cytokine signaling 3
STAP2 signal transducing adaptor family member 2
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT5A signal transducer and activator of transcription 5A
STAT5B signal transducer and activator of transcription 5B