JAK2_knockout_79_GSE26188 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Kinase Perturbations
Category transcriptomics
Type kinase perturbation
Description kinase perturbation identified as [kinase gene symbol]_[perturbation]_[perturbation ID]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE26188
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Genes

600 genes differentially expressed following the JAK2_knockout_79_GSE26188 kinase perturbation from the GEO Signatures of Differentially Expressed Genes for Kinase Perturbations dataset.

increased expression

Symbol Name Standardized Value
CHDH choline dehydrogenase 3.67733
WBP1L WW domain binding protein 1-like 3.00208
LGALSL lectin, galactoside-binding-like 3.00023
HDAC8 histone deacetylase 8 2.99459
DSTYK dual serine/threonine and tyrosine protein kinase 2.85976
CREG1 cellular repressor of E1A-stimulated genes 1 2.8475
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) 2.82402
PMPCB peptidase (mitochondrial processing) beta 2.82318
LUZP1 leucine zipper protein 1 2.81949
APOE apolipoprotein E 2.78519
NUDT12 nudix (nucleoside diphosphate linked moiety X)-type motif 12 2.74104
TMEM239 transmembrane protein 239 2.73494
MSRA methionine sulfoxide reductase A 2.73216
ARL1 ADP-ribosylation factor-like 1 2.72433
FAM151B family with sequence similarity 151, member B 2.65521
CNBP CCHC-type zinc finger, nucleic acid binding protein 2.62341
HDHD2 haloacid dehalogenase-like hydrolase domain containing 2 2.59913
CHMP2B charged multivesicular body protein 2B 2.593
CNTNAP1 contactin associated protein 1 2.58309
PEX11G peroxisomal biogenesis factor 11 gamma 2.54722
HYAL2 hyaluronoglucosaminidase 2 2.54376
HGS hepatocyte growth factor-regulated tyrosine kinase substrate 2.53992
SLMO2 slowmo homolog 2 (Drosophila) 2.52598
ADPRHL2 ADP-ribosylhydrolase like 2 2.51302
SNTB2 syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2) 2.50672
STARD10 StAR-related lipid transfer (START) domain containing 10 2.48734
CTF1 cardiotrophin 1 2.48387
R3HDM4 R3H domain containing 4 2.46367
TMEM194A transmembrane protein 194A 2.45814
OR8G5 olfactory receptor, family 8, subfamily G, member 5 2.44788
TMEM56 transmembrane protein 56 2.4374
CHST10 carbohydrate sulfotransferase 10 2.40322
AREL1 apoptosis resistant E3 ubiquitin protein ligase 1 2.39133
SLC30A8 solute carrier family 30 (zinc transporter), member 8 2.38954
NCOA1 nuclear receptor coactivator 1 2.38063
ACAA2 acetyl-CoA acyltransferase 2 2.3805
GINS4 GINS complex subunit 4 (Sld5 homolog) 2.36506
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) 2.36203
TPD52L2 tumor protein D52-like 2 2.35073
NDUFS2 NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase) 2.34539
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3 2.33327
KIAA1109 KIAA1109 2.3271
RAB21 RAB21, member RAS oncogene family 2.3271
BNIP1 BCL2/adenovirus E1B 19kDa interacting protein 1 2.2848
TTR transthyretin 2.28034
WDFY3 WD repeat and FYVE domain containing 3 2.27261
DUSP10 dual specificity phosphatase 10 2.25703
FOXJ2 forkhead box J2 2.25621
C19ORF53 chromosome 19 open reading frame 53 2.25323
RARA retinoic acid receptor, alpha 2.25209
ASCL3 achaete-scute family bHLH transcription factor 3 2.2503
GALNT13 polypeptide N-acetylgalactosaminyltransferase 13 2.24019
KLHL5 kelch-like family member 5 2.226
GTPBP1 GTP binding protein 1 2.22039
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 2.21094
KSR1 kinase suppressor of ras 1 2.21036
RNF10 ring finger protein 10 2.20859
BTBD1 BTB (POZ) domain containing 1 2.20294
SAPCD2 suppressor APC domain containing 2 2.19471
SLC39A1 solute carrier family 39 (zinc transporter), member 1 2.19004
EPN3 epsin 3 2.17599
GGA1 golgi-associated, gamma adaptin ear containing, ARF binding protein 1 2.17457
CDK18 cyclin-dependent kinase 18 2.17014
LNX2 ligand of numb-protein X 2 2.16708
ZFP57 ZFP57 zinc finger protein 2.16353
UQCRC1 ubiquinol-cytochrome c reductase core protein I 2.15844
FANCB Fanconi anemia, complementation group B 2.15758
MROH7 maestro heat-like repeat family member 7 2.15732
FZD1 frizzled class receptor 1 2.15294
C1ORF54 chromosome 1 open reading frame 54 2.14968
CARKD carbohydrate kinase domain containing 2.14288
CCNG2 cyclin G2 2.13204
IPPK inositol 1,3,4,5,6-pentakisphosphate 2-kinase 2.13103
LIX1L Lix1 homolog (chicken) like 2.12594
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial 2.12386
VCP valosin containing protein 2.11953
BOLA1 bolA family member 1 2.11731
ANKRD40 ankyrin repeat domain 40 2.11479
ATE1 arginyltransferase 1 2.11271
CYHR1 cysteine/histidine-rich 1 2.11012
MIEF2 mitochondrial elongation factor 2 2.0977
AMPH amphiphysin 2.097
MC4R melanocortin 4 receptor 2.09665
C11ORF85 chromosome 11 open reading frame 85 2.09441
CA3 carbonic anhydrase III 2.09135
NCF4 neutrophil cytosolic factor 4, 40kDa 2.08825
TTLL10 tubulin tyrosine ligase-like family member 10 2.08717
ITPA inosine triphosphatase (nucleoside triphosphate pyrophosphatase) 2.08689
EGR2 early growth response 2 2.07785
NDUFA10 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa 2.07
MCEE methylmalonyl CoA epimerase 2.06043
SPIDR scaffolding protein involved in DNA repair 2.06013
NDUFS3 NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase) 2.04587
FBXO4 F-box protein 4 2.03174
NUMBL numb homolog (Drosophila)-like 2.03162
CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin 2.02616
TACC2 transforming, acidic coiled-coil containing protein 2 2.02322
NPAT nuclear protein, ataxia-telangiectasia locus 2.02047
ESD esterase D 2.01928
TOMM40 translocase of outer mitochondrial membrane 40 homolog (yeast) 2.00061
REEP2 receptor accessory protein 2 1.99971
SLC9A3 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 1.99799
IGF2R insulin-like growth factor 2 receptor 1.99493
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha 1.99
AGPAT5 1-acylglycerol-3-phosphate O-acyltransferase 5 1.98564
GLE1 GLE1 RNA export mediator 1.98522
ISCA1 iron-sulfur cluster assembly 1 1.9851
HMGCL 3-hydroxymethyl-3-methylglutaryl-CoA lyase 1.98406
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha 1.98362
SLC22A15 solute carrier family 22, member 15 1.98243
OR8B12 olfactory receptor, family 8, subfamily B, member 12 1.98
TNFSF8 tumor necrosis factor (ligand) superfamily, member 8 1.97088
IDH3G isocitrate dehydrogenase 3 (NAD+) gamma 1.96885
NCAPH2 non-SMC condensin II complex, subunit H2 1.96543
CMTM4 CKLF-like MARVEL transmembrane domain containing 4 1.96487
LYST lysosomal trafficking regulator 1.95928
PGGT1B protein geranylgeranyltransferase type I, beta subunit 1.95845
COASY CoA synthase 1.95812
CSTF1 cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa 1.95108
RTEL1 regulator of telomere elongation helicase 1 1.94406
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha 1.94201
EPT1 ethanolaminephosphotransferase 1 1.94135
MRPL44 mitochondrial ribosomal protein L44 1.94096
MPDU1 mannose-P-dolichol utilization defect 1 1.93411
SOD2 superoxide dismutase 2, mitochondrial 1.92917
COQ9 coenzyme Q9 1.92806
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) 1.92572
EFEMP2 EGF containing fibulin-like extracellular matrix protein 2 1.92483
FAM118A family with sequence similarity 118, member A 1.92208
CHMP1B charged multivesicular body protein 1B 1.92027
GPSM2 G-protein signaling modulator 2 1.91978
PCBD2 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 2 1.91847
ECH1 enoyl CoA hydratase 1, peroxisomal 1.91665
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) 1.91388
HP haptoglobin 1.91188
ITM2B integral membrane protein 2B 1.91152
MRPL10 mitochondrial ribosomal protein L10 1.90989
ZDHHC5 zinc finger, DHHC-type containing 5 1.90691
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3 1.90645
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 1.90494
CLCN3 chloride channel, voltage-sensitive 3 1.90428
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 1.90061
HEXA hexosaminidase A (alpha polypeptide) 1.8914
LRSAM1 leucine rich repeat and sterile alpha motif containing 1 1.88868
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4 1.88605
PSMD11 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 1.88602
KCNH7 potassium channel, voltage gated eag related subfamily H, member 7 1.88495
MRPL4 mitochondrial ribosomal protein L4 1.87996
SLC35F5 solute carrier family 35, member F5 1.87946
TANGO2 transport and golgi organization 2 homolog (Drosophila) 1.87573
DHX32 DEAH (Asp-Glu-Ala-His) box polypeptide 32 1.87144
BCL2L1 BCL2-like 1 1.87104
PSMD3 proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 1.86981
SLC7A14 solute carrier family 7, member 14 1.86783
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1 1.86092
PGM1 phosphoglucomutase 1 1.85432
CYC1 cytochrome c-1 1.85415
PKP4 plakophilin 4 1.85224
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 1.85157
CRAMP1L Crm, cramped-like (Drosophila) 1.85156
GTF2H1 general transcription factor IIH, polypeptide 1, 62kDa 1.85102
PSMD8 proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 1.84841
FAF1 Fas (TNFRSF6) associated factor 1 1.84826
CDHR3 cadherin-related family member 3 1.84512
CPT2 carnitine palmitoyltransferase 2 1.8433
PKP3 plakophilin 3 1.84218
HTRA2 HtrA serine peptidase 2 1.84208
ACAT1 acetyl-CoA acetyltransferase 1 1.84038
LMNB2 lamin B2 1.83998
OR4C12 olfactory receptor, family 4, subfamily C, member 12 1.83966
NDUFB4 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4, 15kDa 1.83955
C2CD2 C2 calcium-dependent domain containing 2 1.83955
GPBAR1 G protein-coupled bile acid receptor 1 1.83769
MYO9B myosin IXB 1.83331
RASA4 RAS p21 protein activator 4 1.82654
ADCK1 aarF domain containing kinase 1 1.82572
PSME3 proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki) 1.82511
CORO1B coronin, actin binding protein, 1B 1.82349
MRPL46 mitochondrial ribosomal protein L46 1.82152
IDNK idnK, gluconokinase homolog (E. coli) 1.82145
CENPT centromere protein T 1.82025
BICD1 bicaudal D homolog 1 (Drosophila) 1.81988
METTL22 methyltransferase like 22 1.81885
GRK6 G protein-coupled receptor kinase 6 1.81704
POLR2G polymerase (RNA) II (DNA directed) polypeptide G 1.8147
TPPP tubulin polymerization promoting protein 1.80772
HEXDC hexosaminidase (glycosyl hydrolase family 20, catalytic domain) containing 1.8042
AP2A1 adaptor-related protein complex 2, alpha 1 subunit 1.80326
NELFCD negative elongation factor complex member C/D 1.80296
UNCX UNC homeobox 1.80169
DUSP22 dual specificity phosphatase 22 1.79964
CERK ceramide kinase 1.79829
AGXT2 alanine--glyoxylate aminotransferase 2 1.79761
TPGS1 tubulin polyglutamylase complex subunit 1 1.7976
RAB11FIP1 RAB11 family interacting protein 1 (class I) 1.7954
OCRL oculocerebrorenal syndrome of Lowe 1.79532
EHF ets homologous factor 1.79503
CWC25 CWC25 spliceosome-associated protein homolog (S. cerevisiae) 1.79256
CD300C CD300c molecule 1.79184
PSMF1 proteasome (prosome, macropain) inhibitor subunit 1 (PI31) 1.79067
PI4KB phosphatidylinositol 4-kinase, catalytic, beta 1.78896
RHBDF2 rhomboid 5 homolog 2 (Drosophila) 1.78493
TUBB2B tubulin, beta 2B class IIb 1.78433
TMEM109 transmembrane protein 109 1.78173
STAT5A signal transducer and activator of transcription 5A 1.77852
STAU2 staufen double-stranded RNA binding protein 2 1.77751
RWDD3 RWD domain containing 3 1.77683
HIPK1 homeodomain interacting protein kinase 1 1.77673
MAP3K11 mitogen-activated protein kinase kinase kinase 11 1.7721
DUS3L dihydrouridine synthase 3-like (S. cerevisiae) 1.7705
EPHB4 EPH receptor B4 1.7647
TMEM176B transmembrane protein 176B 1.76231
HIST3H2A histone cluster 3, H2a 1.75814
RBP4 retinol binding protein 4, plasma 1.75727
GABPB2 GA binding protein transcription factor, beta subunit 2 1.75358
NOS1 nitric oxide synthase 1 (neuronal) 1.75316
PSAP prosaposin 1.74777
SLC26A2 solute carrier family 26 (anion exchanger), member 2 1.7465
DPH5 diphthamide biosynthesis 5 1.74532
PSMA6 proteasome (prosome, macropain) subunit, alpha type, 6 1.7436
ETFA electron-transfer-flavoprotein, alpha polypeptide 1.741
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) 1.7402
LRRC36 leucine rich repeat containing 36 1.73922
FBLN7 fibulin 7 1.73716
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1 1.73673
PPP1R21 protein phosphatase 1, regulatory subunit 21 1.73622
FAM210A family with sequence similarity 210, member A 1.7361
TMEM143 transmembrane protein 143 1.73422
SUCLG1 succinate-CoA ligase, alpha subunit 1.73202
BOLL boule-like RNA-binding protein 1.73191
ALDH5A1 aldehyde dehydrogenase 5 family, member A1 1.73178
CDC42SE1 CDC42 small effector 1 1.73161
SLC29A2 solute carrier family 29 (equilibrative nucleoside transporter), member 2 1.7273
HECTD2 HECT domain containing E3 ubiquitin protein ligase 2 1.72613
TRAM2 translocation associated membrane protein 2 1.72592
DUSP16 dual specificity phosphatase 16 1.72543
ZDHHC11 zinc finger, DHHC-type containing 11 1.725
AKR1C3 aldo-keto reductase family 1, member C3 1.72118
PSMD4 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 1.72027
LDHA lactate dehydrogenase A 1.71994
ATP5H ATP synthase, H+ transporting, mitochondrial Fo complex, subunit d 1.71974
ECE1 endothelin converting enzyme 1 1.71842
SS18L1 synovial sarcoma translocation gene on chromosome 18-like 1 1.71709
PPM1B protein phosphatase, Mg2+/Mn2+ dependent, 1B 1.71397
RAB7A RAB7A, member RAS oncogene family 1.71347
DLST dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) 1.71303
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase 1.71221
MKS1 Meckel syndrome, type 1 1.71214
TMEM55A transmembrane protein 55A 1.71133
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) 1.70841
ETFDH electron-transferring-flavoprotein dehydrogenase 1.70734
MKRN3 makorin ring finger protein 3 1.70653
CASP6 caspase 6, apoptosis-related cysteine peptidase 1.70504
PEX14 peroxisomal biogenesis factor 14 1.70462
PTPN11 protein tyrosine phosphatase, non-receptor type 11 1.7033
GOLGA5 golgin A5 1.70135
ADAM11 ADAM metallopeptidase domain 11 1.70126
ZW10 zw10 kinetochore protein 1.69977
TDO2 tryptophan 2,3-dioxygenase 1.69709
TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 1.69508
MRPL37 mitochondrial ribosomal protein L37 1.6939
SRD5A3 steroid 5 alpha-reductase 3 1.69388
IFNA4 interferon, alpha 4 1.69289
CPNE5 copine V 1.69287
HSD17B4 hydroxysteroid (17-beta) dehydrogenase 4 1.6898
MAN1A1 mannosidase, alpha, class 1A, member 1 1.68794
TMEM125 transmembrane protein 125 1.68629
NUP50 nucleoporin 50kDa 1.68547
COX16 COX16 cytochrome c oxidase assembly homolog (S. cerevisiae) 1.68516
POMGNT2 protein O-linked mannose N-acetylglucosaminyltransferase 2 (beta 1,4-) 1.68279
ANGEL1 angel homolog 1 (Drosophila) 1.6815
IMMT inner membrane protein, mitochondrial 1.68031
FNTA farnesyltransferase, CAAX box, alpha 1.6802
IFRD2 interferon-related developmental regulator 2 1.68018
KIAA0141 KIAA0141 1.67861
SUMO3 small ubiquitin-like modifier 3 1.67859
LRRC39 leucine rich repeat containing 39 1.67829
ORMDL3 ORMDL sphingolipid biosynthesis regulator 3 1.67818
ADGRV1 adhesion G protein-coupled receptor V1 1.6767
PRKCI protein kinase C, iota 1.67489
TLN2 talin 2 1.67448
MAEA macrophage erythroblast attacher 1.67285
GINS3 GINS complex subunit 3 (Psf3 homolog) 1.67265
APOA2 apolipoprotein A-II 1.67161
LRWD1 leucine-rich repeats and WD repeat domain containing 1 1.66816
KCNJ13 potassium channel, inwardly rectifying subfamily J, member 13 1.6677
ENDOD1 endonuclease domain containing 1 1.66717
MPP2 membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) 1.66529
DUSP3 dual specificity phosphatase 3 1.66526
GPR151 G protein-coupled receptor 151 1.66431
EFNB1 ephrin-B1 1.66323
PACSIN2 protein kinase C and casein kinase substrate in neurons 2 1.66263
SHISA7 shisa family member 7 1.66069
RGS14 regulator of G-protein signaling 14 1.66013
TRMT10C tRNA methyltransferase 10 homolog C (S. cerevisiae) 1.6591
RETSAT retinol saturase (all-trans-retinol 13,14-reductase) 1.6569
PTGES2 prostaglandin E synthase 2 1.65658
TACO1 translational activator of mitochondrially encoded cytochrome c oxidase I 1.65437
EGLN1 egl-9 family hypoxia-inducible factor 1 1.65217
PRKCD protein kinase C, delta 1.65102

decreased expression

Symbol Name Standardized Value
CTSG cathepsin G -2.65463
FAM135B family with sequence similarity 135, member B -2.55355
SLC38A9 solute carrier family 38, member 9 -2.55025
ARIH2 ariadne RBR E3 ubiquitin protein ligase 2 -2.53929
RABL6 RAB, member RAS oncogene family-like 6 -2.47063
TMEM231 transmembrane protein 231 -2.44527
PMEPA1 prostate transmembrane protein, androgen induced 1 -2.36963
KIF26B kinesin family member 26B -2.36413
RBP3 retinol binding protein 3, interstitial -2.32289
TMEM154 transmembrane protein 154 -2.31894
MCOLN1 mucolipin 1 -2.28388
DLGAP4 discs, large (Drosophila) homolog-associated protein 4 -2.26177
SIDT2 SID1 transmembrane family, member 2 -2.25511
IFT57 intraflagellar transport 57 -2.24533
TF transferrin -2.21943
PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1 -2.20178
TMC2 transmembrane channel-like 2 -2.16924
KIAA0556 KIAA0556 -2.15379
ZNF213 zinc finger protein 213 -2.13528
LRRC8A leucine rich repeat containing 8 family, member A -2.12569
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5 -2.12526
TBC1D10B TBC1 domain family, member 10B -2.11949
PTH parathyroid hormone -2.10439
DDX19B DEAD (Asp-Glu-Ala-Asp) box polypeptide 19B -2.10364
NOD2 nucleotide-binding oligomerization domain containing 2 -2.09126
IRF5 interferon regulatory factor 5 -2.0871
OR4E2 olfactory receptor, family 4, subfamily E, member 2 -2.05897
CCDC175 coiled-coil domain containing 175 -2.05683
GOPC golgi-associated PDZ and coiled-coil motif containing -2.04168
HTRA4 HtrA serine peptidase 4 -2.03553
KBTBD3 kelch repeat and BTB (POZ) domain containing 3 -2.03517
CEP131 centrosomal protein 131kDa -2.03481
SGCZ sarcoglycan, zeta -2.02287
DYRK4 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4 -2.02157
COA4 cytochrome c oxidase assembly factor 4 homolog (S. cerevisiae) -2.02137
FOXB1 forkhead box B1 -2.0202
KCNG3 potassium channel, voltage gated modifier subfamily G, member 3 -2.00785
WNT11 wingless-type MMTV integration site family, member 11 -2.0042
DAB1 Dab, reelin signal transducer, homolog 1 (Drosophila) -1.99865
KIAA1462 KIAA1462 -1.99395
NEK5 NIMA-related kinase 5 -1.98945
ACAP3 ArfGAP with coiled-coil, ankyrin repeat and PH domains 3 -1.98137
SOGA1 suppressor of glucose, autophagy associated 1 -1.98079
CAPNS2 calpain, small subunit 2 -1.97807
FAM63A family with sequence similarity 63, member A -1.97636
OGDHL oxoglutarate dehydrogenase-like -1.97167
EARS2 glutamyl-tRNA synthetase 2, mitochondrial -1.96488
VGF VGF nerve growth factor inducible -1.9622
TTLL5 tubulin tyrosine ligase-like family member 5 -1.94438
VGLL4 vestigial-like family member 4 -1.92756
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta -1.92677
CSGALNACT2 chondroitin sulfate N-acetylgalactosaminyltransferase 2 -1.9267
LECT1 leukocyte cell derived chemotaxin 1 -1.92633
TACC1 transforming, acidic coiled-coil containing protein 1 -1.92575
TET1 tet methylcytosine dioxygenase 1 -1.92177
ANKRD7 ankyrin repeat domain 7 -1.91144
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 -1.91107
SDR16C5 short chain dehydrogenase/reductase family 16C, member 5 -1.89753
RASEF RAS and EF-hand domain containing -1.89587
ILDR1 immunoglobulin-like domain containing receptor 1 -1.89373
SCN11A sodium channel, voltage gated, type XI alpha subunit -1.89072
RGS3 regulator of G-protein signaling 3 -1.88454
CA4 carbonic anhydrase IV -1.88249
EVC2 Ellis van Creveld syndrome 2 -1.87589
GCAT glycine C-acetyltransferase -1.8709
RUNDC3A RUN domain containing 3A -1.86686
C11ORF88 chromosome 11 open reading frame 88 -1.86331
NAIF1 nuclear apoptosis inducing factor 1 -1.86014
TM4SF20 transmembrane 4 L six family member 20 -1.85632
KCNE5 potassium channel, voltage gated subfamily E regulatory beta subunit 5 -1.85249
IL20RA interleukin 20 receptor, alpha -1.84906
CCS copper chaperone for superoxide dismutase -1.84801
ARL6IP4 ADP-ribosylation factor-like 6 interacting protein 4 -1.84668
ISG20 interferon stimulated exonuclease gene 20kDa -1.84313
FAT4 FAT atypical cadherin 4 -1.83459
TPCN1 two pore segment channel 1 -1.82368
SLC5A8 solute carrier family 5 (sodium/monocarboxylate cotransporter), member 8 -1.82281
CDK20 cyclin-dependent kinase 20 -1.8172
TMEM39B transmembrane protein 39B -1.81105
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1 -1.81065
GTF2F2 general transcription factor IIF, polypeptide 2, 30kDa -1.80848
KRTAP1-3 keratin associated protein 1-3 -1.80361
ADGRL1 adhesion G protein-coupled receptor L1 -1.80122
ZSCAN25 zinc finger and SCAN domain containing 25 -1.79173
USH2A Usher syndrome 2A (autosomal recessive, mild) -1.79068
DNAH3 dynein, axonemal, heavy chain 3 -1.78872
SERPINB12 serpin peptidase inhibitor, clade B (ovalbumin), member 12 -1.78755
CAPN10 calpain 10 -1.78383
ATP9B ATPase, class II, type 9B -1.7821
RASGRF2 Ras protein-specific guanine nucleotide-releasing factor 2 -1.77902
HELQ helicase, POLQ-like -1.77736
TMEM89 transmembrane protein 89 -1.77631
APLNR apelin receptor -1.77189
GPR146 G protein-coupled receptor 146 -1.77059
DBX2 developing brain homeobox 2 -1.76994
DNAJC5B DnaJ (Hsp40) homolog, subfamily C, member 5 beta -1.76718
KCNH1 potassium channel, voltage gated eag related subfamily H, member 1 -1.76673
BATF basic leucine zipper transcription factor, ATF-like -1.76579
F10 coagulation factor X -1.7636
TMEM196 transmembrane protein 196 -1.76294
SP2 Sp2 transcription factor -1.75895
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha -1.74671
CKAP4 cytoskeleton-associated protein 4 -1.74586
RNF149 ring finger protein 149 -1.74216
MED25 mediator complex subunit 25 -1.73849
QTRT1 queuine tRNA-ribosyltransferase 1 -1.73702
DEPDC5 DEP domain containing 5 -1.73636
ACTR1B ARP1 actin-related protein 1 homolog B, centractin beta (yeast) -1.72958
UNC13C unc-13 homolog C (C. elegans) -1.72887
WIPF1 WAS/WASL interacting protein family, member 1 -1.72624
RPRD1B regulation of nuclear pre-mRNA domain containing 1B -1.72044
PLEC plectin -1.71968
HSD3B2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 -1.71927
BARHL2 BarH-like homeobox 2 -1.71826
ZNF205 zinc finger protein 205 -1.71746
PTPN18 protein tyrosine phosphatase, non-receptor type 18 (brain-derived) -1.71547
DNAJC2 DnaJ (Hsp40) homolog, subfamily C, member 2 -1.7147
CASP7 caspase 7, apoptosis-related cysteine peptidase -1.71265
NRXN1 neurexin 1 -1.70983
RPS3 ribosomal protein S3 -1.70767
PCDHB6 protocadherin beta 6 -1.7009
MPND MPN domain containing -1.70087
BARD1 BRCA1 associated RING domain 1 -1.70047
ADGRF1 adhesion G protein-coupled receptor F1 -1.69655
PLEKHH3 pleckstrin homology domain containing, family H (with MyTH4 domain) member 3 -1.69637
MAGEB17 melanoma antigen family B17 -1.69278
GREB1L growth regulation by estrogen in breast cancer-like -1.68718
KCNC2 potassium channel, voltage gated Shaw related subfamily C, member 2 -1.68512
GPM6B glycoprotein M6B -1.68376
NAV1 neuron navigator 1 -1.67895
IPMK inositol polyphosphate multikinase -1.67864
FAM63B family with sequence similarity 63, member B -1.67864
UPP2 uridine phosphorylase 2 -1.67794
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1 -1.67742
CEP152 centrosomal protein 152kDa -1.67712
CNGA3 cyclic nucleotide gated channel alpha 3 -1.67611
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -1.6754
KLHL30 kelch-like family member 30 -1.66653
GPR157 G protein-coupled receptor 157 -1.66529
SERPINB7 serpin peptidase inhibitor, clade B (ovalbumin), member 7 -1.66209
BPIFC BPI fold containing family C -1.66125
RBM44 RNA binding motif protein 44 -1.6601
VEGFA vascular endothelial growth factor A -1.65384
CYP4F11 cytochrome P450, family 4, subfamily F, polypeptide 11 -1.65306
FLNC filamin C, gamma -1.65253
PRUNE2 prune homolog 2 (Drosophila) -1.65163
ALDOC aldolase C, fructose-bisphosphate -1.64805
EPSTI1 epithelial stromal interaction 1 (breast) -1.6439
CRHR2 corticotropin releasing hormone receptor 2 -1.64362
AKAP13 A kinase (PRKA) anchor protein 13 -1.64268
EN2 engrailed homeobox 2 -1.64132
TLE4 transducin-like enhancer of split 4 -1.64072
C16ORF87 chromosome 16 open reading frame 87 -1.63883
CEP89 centrosomal protein 89kDa -1.63679
ALOX5AP arachidonate 5-lipoxygenase-activating protein -1.6314
GMDS GDP-mannose 4,6-dehydratase -1.63117
PADI4 peptidyl arginine deiminase, type IV -1.63081
ZNF319 zinc finger protein 319 -1.62852
ZNF12 zinc finger protein 12 -1.6278
OOSP2 oocyte secreted protein 2 -1.6277
WDR6 WD repeat domain 6 -1.62508
GGA3 golgi-associated, gamma adaptin ear containing, ARF binding protein 3 -1.62393
CCDC176 coiled-coil domain containing 176 -1.62309
ZNF287 zinc finger protein 287 -1.6194
PPP1R16B protein phosphatase 1, regulatory subunit 16B -1.61843
HDGF hepatoma-derived growth factor -1.61544
DUSP15 dual specificity phosphatase 15 -1.61406
C3ORF67 chromosome 3 open reading frame 67 -1.61399
ATP1A4 ATPase, Na+/K+ transporting, alpha 4 polypeptide -1.61189
BCR breakpoint cluster region -1.61059
DLG4 discs, large homolog 4 (Drosophila) -1.60988
SYNPR synaptoporin -1.6097
LMTK2 lemur tyrosine kinase 2 -1.60965
ESRP1 epithelial splicing regulatory protein 1 -1.60866
APOA5 apolipoprotein A-V -1.60571
TSPAN4 tetraspanin 4 -1.60491
G6PC2 glucose-6-phosphatase, catalytic, 2 -1.60361
SLC4A3 solute carrier family 4 (anion exchanger), member 3 -1.60316
RPL10 ribosomal protein L10 -1.60315
FCER2 Fc fragment of IgE, low affinity II, receptor for (CD23) -1.60183
MYL6B myosin, light chain 6B, alkali, smooth muscle and non-muscle -1.59754
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9 -1.59253
OR2A12 olfactory receptor, family 2, subfamily A, member 12 -1.59203
RABGGTA Rab geranylgeranyltransferase, alpha subunit -1.591
FGF16 fibroblast growth factor 16 -1.58741
RIT1 Ras-like without CAAX 1 -1.58724
MYZAP myocardial zonula adherens protein -1.58702
AKT1 v-akt murine thymoma viral oncogene homolog 1 -1.58464
RAB38 RAB38, member RAS oncogene family -1.5792
SPIN1 spindlin 1 -1.57623
PRKD2 protein kinase D2 -1.57562
ZBP1 Z-DNA binding protein 1 -1.57542
FKBPL FK506 binding protein like -1.57366
TSHB thyroid stimulating hormone, beta -1.57359
DNAH8 dynein, axonemal, heavy chain 8 -1.57258
ARHGAP33 Rho GTPase activating protein 33 -1.57252
MYH7B myosin, heavy chain 7B, cardiac muscle, beta -1.56901
OTX1 orthodenticle homeobox 1 -1.56888
C18ORF25 chromosome 18 open reading frame 25 -1.56504
CLCN6 chloride channel, voltage-sensitive 6 -1.56353
SERPINA10 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10 -1.56302
DDX56 DEAD (Asp-Glu-Ala-Asp) box helicase 56 -1.56154
TMEM86A transmembrane protein 86A -1.56067
MRPL30 mitochondrial ribosomal protein L30 -1.55831
CRX cone-rod homeobox -1.55686
ARID4B AT rich interactive domain 4B (RBP1-like) -1.5562
RRH retinal pigment epithelium-derived rhodopsin homolog -1.55608
SPINK5 serine peptidase inhibitor, Kazal type 5 -1.5547
MBD3L1 methyl-CpG binding domain protein 3-like 1 -1.55379
ANO3 anoctamin 3 -1.55306
NSUN2 NOP2/Sun RNA methyltransferase family, member 2 -1.5505
ARMC2 armadillo repeat containing 2 -1.55009
CDH9 cadherin 9, type 2 (T1-cadherin) -1.55003
IL10RB interleukin 10 receptor, beta -1.54888
ACSL6 acyl-CoA synthetase long-chain family member 6 -1.54836
CYB5R1 cytochrome b5 reductase 1 -1.54809
PYCR1 pyrroline-5-carboxylate reductase 1 -1.54808
STARD5 StAR-related lipid transfer (START) domain containing 5 -1.54679
TMEM52B transmembrane protein 52B -1.54589
GFI1 growth factor independent 1 transcription repressor -1.54479
ZNF623 zinc finger protein 623 -1.54376
FLT3 fms-related tyrosine kinase 3 -1.54345
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 -1.54318
ERI3 ERI1 exoribonuclease family member 3 -1.54185
ARID5A AT rich interactive domain 5A (MRF1-like) -1.53744
RNF183 ring finger protein 183 -1.5373
RUFY2 RUN and FYVE domain containing 2 -1.53426
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4 -1.53274
GDF2 growth differentiation factor 2 -1.53261
TMEM255B transmembrane protein 255B -1.53231
AADACL2 arylacetamide deacetylase-like 2 -1.5286
CD70 CD70 molecule -1.52836
RFX1 regulatory factor X, 1 (influences HLA class II expression) -1.52764
HHLA1 HERV-H LTR-associating 1 -1.52573
CTNNBL1 catenin, beta like 1 -1.52464
ODF3L1 outer dense fiber of sperm tails 3-like 1 -1.52225
CRABP2 cellular retinoic acid binding protein 2 -1.52189
MSANTD3 Myb/SANT-like DNA-binding domain containing 3 -1.5216
SOGA3 SOGA family member 3 -1.5204
SHROOM3 shroom family member 3 -1.52024
OPCML opioid binding protein/cell adhesion molecule-like -1.51759
ZDHHC23 zinc finger, DHHC-type containing 23 -1.51696
NKX1-2 NK1 homeobox 2 -1.51599
SLCO4C1 solute carrier organic anion transporter family, member 4C1 -1.51507
EVC Ellis van Creveld protein -1.51446
WRNIP1 Werner helicase interacting protein 1 -1.51398
ONECUT1 one cut homeobox 1 -1.51336
LCA5L Leber congenital amaurosis 5-like -1.51326
CCDC117 coiled-coil domain containing 117 -1.51276
COL2A1 collagen, type II, alpha 1 -1.51159
CENPJ centromere protein J -1.51005
CETN3 centrin, EF-hand protein, 3 -1.50901
OS9 osteosarcoma amplified 9, endoplasmic reticulum lectin -1.50844
AP3M2 adaptor-related protein complex 3, mu 2 subunit -1.50249
MAP3K9 mitogen-activated protein kinase kinase kinase 9 -1.50188
GLP1R glucagon-like peptide 1 receptor -1.50147
OR6S1 olfactory receptor, family 6, subfamily S, member 1 -1.49979
CASQ1 calsequestrin 1 (fast-twitch, skeletal muscle) -1.49944
PSME2 proteasome (prosome, macropain) activator subunit 2 (PA28 beta) -1.49933
ZDHHC12 zinc finger, DHHC-type containing 12 -1.49641
DCT dopachrome tautomerase -1.49641
ONECUT2 one cut homeobox 2 -1.49598
ZNF688 zinc finger protein 688 -1.49546
FBXO16 F-box protein 16 -1.4947
CELSR2 cadherin, EGF LAG seven-pass G-type receptor 2 -1.49135
DLG2 discs, large homolog 2 (Drosophila) -1.49126
LVRN laeverin -1.49097
RYR3 ryanodine receptor 3 -1.4902
OLFM1 olfactomedin 1 -1.48756
DXO decapping exoribonuclease -1.48575
NSL1 NSL1, MIS12 kinetochore complex component -1.48276
KIF1BP KIF1 binding protein -1.4827
TDRD6 tudor domain containing 6 -1.48188
ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 -1.48186
INTS1 integrator complex subunit 1 -1.48138
GNS glucosamine (N-acetyl)-6-sulfatase -1.48098
MANBA mannosidase, beta A, lysosomal -1.48062
PTX3 pentraxin 3, long -1.47564
RPS6KC1 ribosomal protein S6 kinase, 52kDa, polypeptide 1 -1.47563
LEFTY1 left-right determination factor 1 -1.47443
MLLT6 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6 -1.47406
WIPI2 WD repeat domain, phosphoinositide interacting 2 -1.47301
APLP1 amyloid beta (A4) precursor-like protein 1 -1.47274
WAS Wiskott-Aldrich syndrome -1.47264
RPS14 ribosomal protein S14 -1.47247
RFK riboflavin kinase -1.47126
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) -1.47107
HAGH hydroxyacylglutathione hydrolase -1.46968
MARCH11 membrane-associated ring finger (C3HC4) 11 -1.46918
PAG1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1 -1.46845
SPPL3 signal peptide peptidase like 3 -1.46749
ZNF665 zinc finger protein 665 -1.46484
PLEKHO2 pleckstrin homology domain containing, family O member 2 -1.46388
OR11G2 olfactory receptor, family 11, subfamily G, member 2 -1.4622
NDST3 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3 -1.46132
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3 -1.4612
ZPLD1 zona pellucida-like domain containing 1 -1.46119
TCF25 transcription factor 25 (basic helix-loop-helix) -1.46031
LTB4R2 leukotriene B4 receptor 2 -1.45977
TWIST2 twist family bHLH transcription factor 2 -1.45863