| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | Janus kinase 3|The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease). [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 3718) |
| External Link | https://ncbi.nlm.nih.gov/gene/3718 |
| Similar Terms | |
| Downloads & Tools |
499 genes differentially expressed following the JAK3 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| APOD | apolipoprotein D | 0.0140357 |
| FN1 | fibronectin 1 | 0.0126206 |
| IFI44L | interferon-induced protein 44-like | 0.012562 |
| IGSF3 | immunoglobulin superfamily, member 3 | 0.0113243 |
| DYNLL1 | dynein, light chain, LC8-type 1 | 0.0113105 |
| MX1 | MX dynamin-like GTPase 1 | 0.0109364 |
| SIK1 | salt-inducible kinase 1 | 0.0108381 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0107073 |
| LAMB1 | laminin, beta 1 | 0.0106486 |
| HSPB8 | heat shock 22kDa protein 8 | 0.0106089 |
| MMP1 | matrix metallopeptidase 1 | 0.0105576 |
| SRPX | sushi-repeat containing protein, X-linked | 0.0104329 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0104308 |
| SYNM | synemin, intermediate filament protein | 0.0104055 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0102904 |
| GNAS | GNAS complex locus | 0.00960754 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.00940217 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.00939309 |
| LY6E | lymphocyte antigen 6 complex, locus E | 0.0093243 |
| AMOTL2 | angiomotin like 2 | 0.00930956 |
| NID2 | nidogen 2 (osteonidogen) | 0.00926886 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.00921288 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 | 0.00915313 |
| GSTM3 | glutathione S-transferase mu 3 (brain) | 0.00894264 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.00879349 |
| SYNGR3 | synaptogyrin 3 | 0.00877769 |
| PLAAT3 | phospholipase A and acyltransferase 3 | 0.00877753 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.00875891 |
| PMP22 | peripheral myelin protein 22 | 0.00858967 |
| SIDT2 | SID1 transmembrane family, member 2 | 0.00850336 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | 0.00841189 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.00831787 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | 0.00816544 |
| IER5 | immediate early response 5 | 0.00809709 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | 0.0080872 |
| KDM5D | lysine (K)-specific demethylase 5D | 0.00805522 |
| STK10 | serine/threonine kinase 10 | 0.00794864 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 | 0.00793617 |
| GNG11 | guanine nucleotide binding protein (G protein), gamma 11 | 0.00776935 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | 0.00776671 |
| TCTA | T-cell leukemia translocation altered | 0.00769588 |
| SLC38A1 | solute carrier family 38, member 1 | 0.0076928 |
| KANK1 | KN motif and ankyrin repeat domains 1 | 0.00768972 |
| ITM2A | integral membrane protein 2A | 0.007659 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | 0.00765565 |
| TNS3 | tensin 3 | 0.00759557 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.00757698 |
| LOXL2 | lysyl oxidase-like 2 | 0.00756935 |
| AREG | amphiregulin | 0.00746229 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.00741824 |
| ABCC1 | ATP-binding cassette, sub-family C (CFTR/MRP), member 1 | 0.00740812 |
| NOTCH2NL | notch 2 N-terminal like | 0.00739544 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.00737227 |
| STC2 | stanniocalcin 2 | 0.00733266 |
| KRT18 | keratin 18, type I | 0.00727062 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) | 0.00727012 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | 0.00725097 |
| COL9A3 | collagen, type IX, alpha 3 | 0.00723228 |
| TUFT1 | tuftelin 1 | 0.00719278 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.00717388 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | 0.00709631 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 | 0.0070637 |
| CTSD | cathepsin D | 0.00702825 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | 0.00701052 |
| GPX3 | glutathione peroxidase 3 | 0.00694218 |
| NETO2 | neuropilin (NRP) and tolloid (TLL)-like 2 | 0.00692636 |
| RTN2 | reticulon 2 | 0.0069141 |
| CADM1 | cell adhesion molecule 1 | 0.00689877 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.00687917 |
| PLXNB2 | plexin B2 | 0.00687517 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.00684725 |
| S100A10 | S100 calcium binding protein A10 | 0.00683367 |
| CRISPLD2 | cysteine-rich secretory protein LCCL domain containing 2 | 0.00681665 |
| KRT14 | keratin 14, type I | 0.00681638 |
| MX2 | MX dynamin-like GTPase 2 | 0.00680717 |
| HSPA1A | heat shock 70kDa protein 1A | 0.00675879 |
| FSTL1 | follistatin-like 1 | 0.00671418 |
| COL3A1 | collagen, type III, alpha 1 | 0.00668383 |
| NID1 | nidogen 1 | 0.00668202 |
| HEY1 | hes-related family bHLH transcription factor with YRPW motif 1 | 0.00667593 |
| MGLL | monoglyceride lipase | 0.00662475 |
| ACADVL | acyl-CoA dehydrogenase, very long chain | 0.00661911 |
| PEG10 | paternally expressed 10 | 0.00659734 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0065899 |
| ITGAV | integrin, alpha V | 0.00657844 |
| MICAL1 | microtubule associated monooxygenase, calponin and LIM domain containing 1 | 0.0065525 |
| MXRA7 | matrix-remodelling associated 7 | 0.00647748 |
| PIEZO2 | piezo-type mechanosensitive ion channel component 2 | 0.00645003 |
| KYNU | kynureninase | 0.0064422 |
| OBSL1 | obscurin-like 1 | 0.00639134 |
| CD36 | CD36 molecule (thrombospondin receptor) | 0.00634442 |
| CCL19 | chemokine (C-C motif) ligand 19 | 0.00633899 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | 0.00632285 |
| IFI44 | interferon-induced protein 44 | 0.00631841 |
| PTK2B | protein tyrosine kinase 2 beta | 0.00630756 |
| RFTN1 | raftlin, lipid raft linker 1 | 0.00627098 |
| SPATA20 | spermatogenesis associated 20 | 0.00626057 |
| RGS16 | regulator of G-protein signaling 16 | 0.00624181 |
| CX3CR1 | chemokine (C-X3-C motif) receptor 1 | 0.00623857 |
| TXLNA | taxilin alpha | 0.00621674 |
| OLFML2A | olfactomedin-like 2A | 0.0062038 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | 0.006198 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 | 0.00615284 |
| TENM3 | teneurin transmembrane protein 3 | 0.00615176 |
| CSAD | cysteine sulfinic acid decarboxylase | 0.00613486 |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) | 0.00612178 |
| VCL | vinculin | 0.00609406 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.00608311 |
| IRF7 | interferon regulatory factor 7 | 0.00607621 |
| LDOC1 | leucine zipper, down-regulated in cancer 1 | 0.00607095 |
| RABEP2 | rabaptin, RAB GTPase binding effector protein 2 | 0.00604498 |
| CXCL10 | chemokine (C-X-C motif) ligand 10 | 0.00598569 |
| TUBB2B | tubulin, beta 2B class IIb | 0.00595698 |
| CSRP1 | cysteine and glycine-rich protein 1 | 0.00595508 |
| ANGPT1 | angiopoietin 1 | 0.00595457 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.00595441 |
| DLK1 | delta-like 1 homolog (Drosophila) | 0.00594808 |
| PEG3 | paternally expressed 3 | 0.00594384 |
| PGRMC2 | progesterone receptor membrane component 2 | 0.00592005 |
| COL15A1 | collagen, type XV, alpha 1 | 0.00591619 |
| JAM3 | junctional adhesion molecule 3 | 0.00591432 |
| SKIV2L | superkiller viralicidic activity 2-like (S. cerevisiae) | 0.00591286 |
| ANGPTL2 | angiopoietin-like 2 | 0.00585925 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.00584832 |
| COBLL1 | cordon-bleu WH2 repeat protein-like 1 | 0.00584761 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.00584303 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | 0.00580593 |
| FAM13A | family with sequence similarity 13, member A | 0.00577334 |
| HTRA1 | HtrA serine peptidase 1 | 0.005745 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa | 0.0057153 |
| DCT | dopachrome tautomerase | 0.00570275 |
| XAF1 | XIAP associated factor 1 | 0.00569301 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | 0.00568919 |
| ECM1 | extracellular matrix protein 1 | 0.00568865 |
| CBS | cystathionine-beta-synthase | 0.00568519 |
| SDC3 | syndecan 3 | 0.00566872 |
| CTSA | cathepsin A | 0.00565479 |
| GOLGA8A | golgin A8 family, member A | 0.00564536 |
| FST | follistatin | 0.00563747 |
| ZNF512B | zinc finger protein 512B | 0.00559927 |
| STK25 | serine/threonine kinase 25 | 0.00559527 |
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide | 0.00559008 |
| CDV3 | CDV3 homolog (mouse) | 0.00559006 |
| NNMT | nicotinamide N-methyltransferase | 0.00558798 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | 0.00558525 |
| KRT7 | keratin 7, type II | 0.00558297 |
| GGT1 | gamma-glutamyltransferase 1 | 0.00556603 |
| MID1 | midline 1 | 0.00556334 |
| PCOLCE | procollagen C-endopeptidase enhancer | 0.0055527 |
| NOTCH1 | notch 1 | 0.00553666 |
| FOXJ3 | forkhead box J3 | 0.0055333 |
| SOX10 | SRY (sex determining region Y)-box 10 | 0.00550308 |
| COL7A1 | collagen, type VII, alpha 1 | 0.00549462 |
| PXDC1 | PX domain containing 1 | 0.00549451 |
| MAF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog | 0.00548595 |
| CXCL13 | chemokine (C-X-C motif) ligand 13 | 0.00548203 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | 0.00544481 |
| COL5A2 | collagen, type V, alpha 2 | 0.00542213 |
| QSOX1 | quiescin Q6 sulfhydryl oxidase 1 | 0.00540764 |
| GBP1 | guanylate binding protein 1, interferon-inducible | 0.00540033 |
| PXDN | peroxidasin | 0.00539476 |
| C3 | complement component 3 | 0.00539026 |
| IGFBP4 | insulin-like growth factor binding protein 4 | 0.00537845 |
| DUSP5 | dual specificity phosphatase 5 | 0.00536697 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.00532533 |
| POLR3E | polymerase (RNA) III (DNA directed) polypeptide E (80kD) | 0.00528843 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.00527144 |
| KRT5 | keratin 5, type II | 0.0052565 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | 0.00524182 |
| PCDH9 | protocadherin 9 | 0.0052358 |
| PARP12 | poly (ADP-ribose) polymerase family, member 12 | 0.00522184 |
| PABPC4 | poly(A) binding protein, cytoplasmic 4 (inducible form) | 0.00516931 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0051629 |
| BEX4 | brain expressed, X-linked 4 | 0.00515627 |
| SPINK2 | serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) | 0.00515551 |
| KRT8 | keratin 8, type II | 0.00515477 |
| COTL1 | coactosin-like F-actin binding protein 1 | 0.0051447 |
| MAPK1IP1L | mitogen-activated protein kinase 1 interacting protein 1-like | 0.00511699 |
| TPM1 | tropomyosin 1 (alpha) | 0.00511669 |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | 0.00511093 |
| MTCL1 | microtubule crosslinking factor 1 | 0.00510902 |
| MET | MET proto-oncogene, receptor tyrosine kinase | 0.00510839 |
| PKD1P1 | polycystic kidney disease 1 (autosomal dominant) pseudogene 1 | 0.00508765 |
| NPY1R | neuropeptide Y receptor Y1 | 0.00508699 |
| IRS1 | insulin receptor substrate 1 | 0.005085 |
| RGS1 | regulator of G-protein signaling 1 | 0.00507492 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.00507202 |
| TSPAN4 | tetraspanin 4 | 0.00506156 |
| GLDC | glycine dehydrogenase (decarboxylating) | 0.00505403 |
| YTHDF1 | YTH N(6)-methyladenosine RNA binding protein 1 | 0.00504543 |
| ARHGEF7 | Rho guanine nucleotide exchange factor (GEF) 7 | 0.005017 |
| PLD3 | phospholipase D family, member 3 | 0.00500134 |
| MPDZ | multiple PDZ domain protein | 0.0049984 |
| CGA | glycoprotein hormones, alpha polypeptide | 0.00497337 |
| COL6A1 | collagen, type VI, alpha 1 | 0.00496495 |
| SGK1 | serum/glucocorticoid regulated kinase 1 | 0.00495415 |
| NOTCH2 | notch 2 | 0.00495372 |
| PHLDA2 | pleckstrin homology-like domain, family A, member 2 | 0.00495311 |
| CCNA2 | cyclin A2 | 0.00494473 |
| NRCAM | neuronal cell adhesion molecule | 0.00494339 |
| SPON2 | spondin 2, extracellular matrix protein | 0.0049309 |
| COLEC12 | collectin sub-family member 12 | 0.00492991 |
| PDGFD | platelet derived growth factor D | 0.00490037 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | 0.0048899 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.00488946 |
| PLCXD1 | phosphatidylinositol-specific phospholipase C, X domain containing 1 | 0.00487062 |
| PLS3 | plastin 3 | 0.00486834 |
| RHBDF1 | rhomboid 5 homolog 1 (Drosophila) | 0.00486517 |
| L1CAM | L1 cell adhesion molecule | 0.00484151 |
| TAP1 | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) | 0.00482819 |
| ARHGEF2 | Rho/Rac guanine nucleotide exchange factor (GEF) 2 | 0.00482422 |
| OLFML3 | olfactomedin-like 3 | 0.00482077 |
| WWC3 | WWC family member 3 | 0.00482059 |
| DDX21 | DEAD (Asp-Glu-Ala-Asp) box helicase 21 | 0.00481963 |
| MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 | 0.00481656 |
| KLF11 | Kruppel-like factor 11 | 0.00481231 |
| RBL2 | retinoblastoma-like 2 | 0.0048059 |
| MAMLD1 | mastermind-like domain containing 1 | 0.00480579 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.00479521 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | 0.00479451 |
| TGFBR3 | transforming growth factor, beta receptor III | 0.0047818 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.00477278 |
| CEBPB | CCAAT/enhancer binding protein (C/EBP), beta | 0.00477117 |
| MFAP3L | microfibrillar-associated protein 3-like | 0.00476219 |
| PLLP | plasmolipin | 0.00475983 |
| AHR | aryl hydrocarbon receptor | 0.00475268 |
| JMJD6 | jumonji domain containing 6 | 0.00475121 |
| ADIRF | adipogenesis regulatory factor | 0.0047445 |
| PLXNA1 | plexin A1 | 0.00471669 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0047142 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.00471371 |
| APBA2 | amyloid beta (A4) precursor protein-binding, family A, member 2 | 0.00470539 |
| CCND3 | cyclin D3 | 0.00469681 |
| CTSK | cathepsin K | 0.00468951 |
| PIEZO1 | piezo-type mechanosensitive ion channel component 1 | 0.00467478 |
| MATN2 | matrilin 2 | 0.0046635 |
| S100B | S100 calcium binding protein B | 0.00466311 |
| SCUBE2 | signal peptide, CUB domain, EGF-like 2 | 0.00465449 |
| ZDHHC7 | zinc finger, DHHC-type containing 7 | 0.00464244 |
| MIR22HG | MIR22 host gene | 0.00461916 |
| ANPEP | alanyl (membrane) aminopeptidase | 0.00461134 |
| EHD2 | EH-domain containing 2 | 0.0046111 |
| DEGS1 | delta(4)-desaturase, sphingolipid 1 | 0.00460231 |
| DDR2 | discoidin domain receptor tyrosine kinase 2 | 0.00460118 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.00459579 |
| POGLUT2 | protein O-glucosyltransferase 2 | 0.00458417 |
| IFNAR1 | interferon (alpha, beta and omega) receptor 1 | 0.00457862 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | 0.00457653 |
| FBN2 | fibrillin 2 | 0.00456822 |
| SLC2A6 | solute carrier family 2 (facilitated glucose transporter), member 6 | 0.00456699 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PAK1 | p21 protein (Cdc42/Rac)-activated kinase 1 | -0.0152023 |
| E2F2 | E2F transcription factor 2 | -0.0123603 |
| ZDHHC6 | zinc finger, DHHC-type containing 6 | -0.0109417 |
| WDR7 | WD repeat domain 7 | -0.0106334 |
| LTF | lactotransferrin | -0.00972788 |
| GCA | grancalcin, EF-hand calcium binding protein | -0.00950353 |
| SLPI | secretory leukocyte peptidase inhibitor | -0.00932182 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | -0.00903217 |
| WFDC2 | WAP four-disulfide core domain 2 | -0.00889685 |
| ESR1 | estrogen receptor 1 | -0.00879114 |
| TXNDC9 | thioredoxin domain containing 9 | -0.00869318 |
| FOXG1 | forkhead box G1 | -0.00863463 |
| TXNL1 | thioredoxin-like 1 | -0.00860413 |
| AKR1C3 | aldo-keto reductase family 1, member C3 | -0.00853002 |
| NAT1 | N-acetyltransferase 1 (arylamine N-acetyltransferase) | -0.00852493 |
| SYT1 | synaptotagmin I | -0.00850336 |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit | -0.0081498 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | -0.00809805 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | -0.00804463 |
| CA2 | carbonic anhydrase II | -0.0079702 |
| EMX2 | empty spiracles homeobox 2 | -0.00781581 |
| NRGN | neurogranin (protein kinase C substrate, RC3) | -0.00759111 |
| COMMD10 | COMM domain containing 10 | -0.00756478 |
| CALML4 | calmodulin-like 4 | -0.00739368 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 | -0.00729124 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | -0.00721821 |
| MSLN | mesothelin | -0.0071873 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | -0.00716803 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | -0.00712545 |
| ITGB1BP1 | integrin beta 1 binding protein 1 | -0.00707383 |
| OLFM4 | olfactomedin 4 | -0.00697882 |
| DLST | dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) | -0.00697259 |
| ATG5 | autophagy related 5 | -0.0068597 |
| RNF167 | ring finger protein 167 | -0.00681931 |
| TSPAN6 | tetraspanin 6 | -0.00677748 |
| MECOM | MDS1 and EVI1 complex locus | -0.00677185 |
| KLK6 | kallikrein-related peptidase 6 | -0.00676392 |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit | -0.00663938 |
| COG5 | component of oligomeric golgi complex 5 | -0.00658717 |
| GRIA2 | glutamate receptor, ionotropic, AMPA 2 | -0.00655694 |
| ARMC1 | armadillo repeat containing 1 | -0.00646647 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | -0.00641975 |
| MPO | myeloperoxidase | -0.00641099 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 | -0.00640463 |
| DACH1 | dachshund family transcription factor 1 | -0.00640265 |
| BANK1 | B-cell scaffold protein with ankyrin repeats 1 | -0.00635918 |
| COMMD8 | COMM domain containing 8 | -0.00635369 |
| MAP2K6 | mitogen-activated protein kinase kinase 6 | -0.00630659 |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 | -0.00627338 |
| MMP12 | matrix metallopeptidase 12 | -0.00621873 |
| PEX2 | peroxisomal biogenesis factor 2 | -0.00620869 |
| OTULINL | OTU deubiquitinase with linear linkage specificity like | -0.00620334 |
| ST6GALNAC5 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 | -0.00619603 |
| CLNS1A | chloride channel, nucleotide-sensitive, 1A | -0.00618509 |
| SNAP25 | synaptosomal-associated protein, 25kDa | -0.00618408 |
| ZNF277 | zinc finger protein 277 | -0.00618368 |
| ACTB | actin, beta | -0.00618201 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | -0.00617701 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | -0.00614078 |
| CPOX | coproporphyrinogen oxidase | -0.00612254 |
| CLIC5 | chloride intracellular channel 5 | -0.00610213 |
| SOX17 | SRY (sex determining region Y)-box 17 | -0.00609418 |
| WDR61 | WD repeat domain 61 | -0.006066 |
| OLA1 | Obg-like ATPase 1 | -0.00600313 |
| LIPT1 | lipoyltransferase 1 | -0.00599444 |
| SLC44A4 | solute carrier family 44, member 4 | -0.00598705 |
| LSM1 | LSM1, U6 small nuclear RNA associated | -0.00591756 |
| LSM2 | LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -0.00591603 |
| ADD3 | adducin 3 (gamma) | -0.00591274 |
| RHOA | ras homolog family member A | -0.00587301 |
| NEK2 | NIMA-related kinase 2 | -0.00586186 |
| CRYM | crystallin, mu | -0.00586123 |
| BCL11A | B-cell CLL/lymphoma 11A (zinc finger protein) | -0.00586117 |
| ANG | angiogenin, ribonuclease, RNase A family, 5 | -0.00579788 |
| ADPRM | ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent | -0.00578019 |
| SPON1 | spondin 1, extracellular matrix protein | -0.00572037 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming | -0.00571726 |
| ERAP2 | endoplasmic reticulum aminopeptidase 2 | -0.00571602 |
| TMEM106B | transmembrane protein 106B | -0.00566278 |
| DNTT | DNA nucleotidylexotransferase | -0.00566069 |
| CDC6 | cell division cycle 6 | -0.00565899 |
| MYB | v-myb avian myeloblastosis viral oncogene homolog | -0.00564224 |
| RSL24D1 | ribosomal L24 domain containing 1 | -0.0056151 |
| PTPN2 | protein tyrosine phosphatase, non-receptor type 2 | -0.00559369 |
| CSRP3 | cysteine and glycine-rich protein 3 (cardiac LIM protein) | -0.00558401 |
| TIMM9 | translocase of inner mitochondrial membrane 9 homolog (yeast) | -0.00558012 |
| ENPP4 | ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative) | -0.00554025 |
| PRDX2 | peroxiredoxin 2 | -0.0055342 |
| ESD | esterase D | -0.00552047 |
| DCUN1D1 | DCN1, defective in cullin neddylation 1, domain containing 1 | -0.00551473 |
| RPRD1A | regulation of nuclear pre-mRNA domain containing 1A | -0.00551058 |
| TPGS2 | tubulin polyglutamylase complex subunit 2 | -0.00550852 |
| CDC42 | cell division cycle 42 | -0.00549097 |
| SPTSSA | serine palmitoyltransferase, small subunit A | -0.00547 |
| AQP9 | aquaporin 9 | -0.00546666 |
| UGP2 | UDP-glucose pyrophosphorylase 2 | -0.00545777 |
| SDHAF3 | succinate dehydrogenase complex assembly factor 3 | -0.00544172 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | -0.00543971 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 | -0.00543687 |
| CLDND1 | claudin domain containing 1 | -0.00543368 |
| FKBP5 | FK506 binding protein 5 | -0.0054305 |
| ELANE | elastase, neutrophil expressed | -0.00542833 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.00542736 |
| ASNSD1 | asparagine synthetase domain containing 1 | -0.00541072 |
| S100A12 | S100 calcium binding protein A12 | -0.00539999 |
| ACYP2 | acylphosphatase 2, muscle type | -0.00535933 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.00532865 |
| GSTO1 | glutathione S-transferase omega 1 | -0.00532105 |
| CGRRF1 | cell growth regulator with ring finger domain 1 | -0.00531957 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.0053118 |
| HP | haptoglobin | -0.00529133 |
| PIP5K1B | phosphatidylinositol-4-phosphate 5-kinase, type I, beta | -0.00528803 |
| COX7A2L | cytochrome c oxidase subunit VIIa polypeptide 2 like | -0.00526943 |
| AK4 | adenylate kinase 4 | -0.00524102 |
| MRPL19 | mitochondrial ribosomal protein L19 | -0.00523717 |
| SH3YL1 | SH3 and SYLF domain containing 1 | -0.00522405 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | -0.0052112 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0052074 |
| RBM3 | RNA binding motif (RNP1, RRM) protein 3 | -0.00519645 |
| ZNF443 | zinc finger protein 443 | -0.0051962 |
| PLN | phospholamban | -0.00517422 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.00517247 |
| ME2 | malic enzyme 2, NAD(+)-dependent, mitochondrial | -0.0051602 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | -0.0051501 |
| CDK14 | cyclin-dependent kinase 14 | -0.00514324 |
| TERF2 | telomeric repeat binding factor 2 | -0.00512449 |
| VBP1 | von Hippel-Lindau binding protein 1 | -0.00512308 |
| MICU2 | mitochondrial calcium uptake 2 | -0.00510977 |
| ESRP1 | epithelial splicing regulatory protein 1 | -0.00510575 |
| HOXB6 | homeobox B6 | -0.00510066 |
| PDCD10 | programmed cell death 10 | -0.00509143 |
| RAD51AP1 | RAD51 associated protein 1 | -0.00507905 |
| CNOT8 | CCR4-NOT transcription complex, subunit 8 | -0.00507234 |
| POT1 | protection of telomeres 1 | -0.00506065 |
| CLDN10 | claudin 10 | -0.00505156 |
| PEX3 | peroxisomal biogenesis factor 3 | -0.0050448 |
| SSR3 | signal sequence receptor, gamma (translocon-associated protein gamma) | -0.00502692 |
| ETNPPL | ethanolamine-phosphate phospho-lyase | -0.00501951 |
| GALNT3 | polypeptide N-acetylgalactosaminyltransferase 3 | -0.0049937 |
| TSPAN8 | tetraspanin 8 | -0.00499298 |
| RESF1 | retroelement silencing factor 1 | -0.00498932 |
| H1-0 | H1.0 linker histone | -0.00498517 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | -0.00498062 |
| COX7A1 | cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) | -0.00496198 |
| CETN2 | centrin, EF-hand protein, 2 | -0.00495302 |
| IFT52 | intraflagellar transport 52 | -0.00494643 |
| WIF1 | WNT inhibitory factor 1 | -0.00494491 |
| ZNF267 | zinc finger protein 267 | -0.00493981 |
| SULT1B1 | sulfotransferase family, cytosolic, 1B, member 1 | -0.00493706 |
| RPS5 | ribosomal protein S5 | -0.00492088 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | -0.00491796 |
| MRPL48 | mitochondrial ribosomal protein L48 | -0.00491538 |
| LRIG1 | leucine-rich repeats and immunoglobulin-like domains 1 | -0.00491099 |
| JCHAIN | joining chain of multimeric IgA and IgM | -0.00489476 |
| EPHA1 | EPH receptor A1 | -0.00489334 |
| AGPS | alkylglycerone phosphate synthase | -0.00489268 |
| CCK | cholecystokinin | -0.00488876 |
| PI3 | peptidase inhibitor 3, skin-derived | -0.00488739 |
| CLEC4A | C-type lectin domain family 4, member A | -0.00488376 |
| ZNF430 | zinc finger protein 430 | -0.00488352 |
| MAGT1 | magnesium transporter 1 | -0.0048738 |
| RAB32 | RAB32, member RAS oncogene family | -0.00486828 |
| PBK | PDZ binding kinase | -0.00486459 |
| HMGB1 | high mobility group box 1 | -0.0048529 |
| ABHD10 | abhydrolase domain containing 10 | -0.00484503 |
| LAGE3 | L antigen family, member 3 | -0.00484433 |
| ARID4A | AT rich interactive domain 4A (RBP1-like) | -0.00482633 |
| ARPC5 | actin related protein 2/3 complex, subunit 5, 16kDa | -0.00481376 |
| RAB25 | RAB25, member RAS oncogene family | -0.00481036 |
| TMEM38B | transmembrane protein 38B | -0.00480762 |
| HBB | hemoglobin, beta | -0.00478922 |
| CCNB1IP1 | cyclin B1 interacting protein 1, E3 ubiquitin protein ligase | -0.00478578 |
| TMEM100 | transmembrane protein 100 | -0.00478116 |
| RGS10 | regulator of G-protein signaling 10 | -0.00473747 |
| ORC4 | origin recognition complex, subunit 4 | -0.00473744 |
| HAUS4 | HAUS augmin-like complex, subunit 4 | -0.00472649 |
| KRCC1 | lysine-rich coiled-coil 1 | -0.00472638 |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | -0.00472396 |
| TREM1 | triggering receptor expressed on myeloid cells 1 | -0.00472372 |
| HIGD1A | HIG1 hypoxia inducible domain family, member 1A | -0.00472015 |
| CLDN7 | claudin 7 | -0.00470627 |
| RMI1 | RecQ mediated genome instability 1 | -0.00470425 |
| TSPAN1 | tetraspanin 1 | -0.00469704 |
| SLC2A5 | solute carrier family 2 (facilitated glucose/fructose transporter), member 5 | -0.00469671 |
| PCSK1 | proprotein convertase subtilisin/kexin type 1 | -0.00469271 |
| CH25H | cholesterol 25-hydroxylase | -0.00468231 |
| PFDN5 | prefoldin subunit 5 | -0.0046817 |
| CYP4F3 | cytochrome P450, family 4, subfamily F, polypeptide 3 | -0.00467915 |
| NUP37 | nucleoporin 37kDa | -0.00467816 |
| MRPS18B | mitochondrial ribosomal protein S18B | -0.00467691 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | -0.00466948 |
| GLUL | glutamate-ammonia ligase | -0.00466536 |
| EIF5A | eukaryotic translation initiation factor 5A | -0.00465957 |
| EAF2 | ELL associated factor 2 | -0.00464816 |
| AAGAB | alpha- and gamma-adaptin binding protein | -0.00464454 |
| ANXA3 | annexin A3 | -0.00463615 |
| HIST1H2AC | histone cluster 1, H2ac | -0.00462465 |
| DOP1B | DOP1 leucine zipper like protein B | -0.00461937 |
| ANKRD49 | ankyrin repeat domain 49 | -0.00460841 |
| CRBN | cereblon | -0.00460029 |
| GSTA1 | glutathione S-transferase alpha 1 | -0.00459709 |
| MYT1L | myelin transcription factor 1-like | -0.00459653 |
| GTPBP8 | GTP-binding protein 8 (putative) | -0.00459207 |
| GTF2H4 | general transcription factor IIH, polypeptide 4, 52kDa | -0.00459126 |
| CLDN3 | claudin 3 | -0.00458782 |
| POLB | polymerase (DNA directed), beta | -0.00458506 |
| DCK | deoxycytidine kinase | -0.00458183 |
| XK | X-linked Kx blood group | -0.00458172 |
| FHIT | fragile histidine triad | -0.00458152 |
| PRMT1 | protein arginine methyltransferase 1 | -0.00458046 |
| DNAJC7 | DnaJ (Hsp40) homolog, subfamily C, member 7 | -0.00457805 |
| TCEA1 | transcription elongation factor A (SII), 1 | -0.00456459 |
| P2RY2 | purinergic receptor P2Y, G-protein coupled, 2 | -0.00454283 |
| ATP5F1C | ATP synthase F1 subunit gamma | -0.00453816 |
| CLDN8 | claudin 8 | -0.00453776 |
| PTH2R | parathyroid hormone 2 receptor | -0.00453699 |
| YIPF5 | Yip1 domain family, member 5 | -0.00453505 |
| THAP12 | THAP domain containing 12 | -0.00450851 |
| GET3 | guided entry of tail-anchored proteins factor 3, ATPase | -0.00450629 |
| SELENOT | selenoprotein T | -0.00450141 |
| GADD45G | growth arrest and DNA-damage-inducible, gamma | -0.00449493 |
| PPP2R3C | protein phosphatase 2, regulatory subunit B'', gamma | -0.00448129 |
| BMP4 | bone morphogenetic protein 4 | -0.00448023 |
| TPD52L1 | tumor protein D52-like 1 | -0.00447964 |
| PALLD | palladin, cytoskeletal associated protein | -0.00447944 |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B | -0.00447726 |
| SCGB1A1 | secretoglobin, family 1A, member 1 (uteroglobin) | -0.0044697 |
| PCLO | piccolo presynaptic cytomatrix protein | -0.00446911 |
| ZNHIT3 | zinc finger, HIT-type containing 3 | -0.00446268 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase | -0.00444662 |
| DMBT1 | deleted in malignant brain tumors 1 | -0.0044416 |
| MED6 | mediator complex subunit 6 | -0.00444008 |
| IL1B | interleukin 1, beta | -0.00441301 |
| ACP1 | acid phosphatase 1, soluble | -0.00441054 |
| PLIN3 | perilipin 3 | -0.00440407 |
| PDZK1IP1 | PDZK1 interacting protein 1 | -0.0043936 |
| PARPBP | PARP1 binding protein | -0.00439082 |
| TMEM70 | transmembrane protein 70 | -0.00438766 |
| LY6H | lymphocyte antigen 6 complex, locus H | -0.00438214 |
| SDF2L1 | stromal cell-derived factor 2-like 1 | -0.00437695 |
| PRKACB | protein kinase, cAMP-dependent, catalytic, beta | -0.00436413 |
| GSTT1 | glutathione S-transferase theta 1 | -0.00435016 |
| MSX1 | msh homeobox 1 | -0.00434403 |
| ALDOB | aldolase B, fructose-bisphosphate | -0.00434215 |
| CRABP2 | cellular retinoic acid binding protein 2 | -0.00433633 |
| GUCY2C | guanylate cyclase 2C | -0.00433514 |
| LILRA2 | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2 | -0.00433284 |
| ANO1 | anoctamin 1, calcium activated chloride channel | -0.00433143 |
| DEFA4 | defensin, alpha 4, corticostatin | -0.00432797 |
