JAK3 Gene Set

Dataset MSigDB Cancer Gene Co-expression Modules
Category transcriptomics
Type co-expressed gene
Description Janus kinase 3|The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease). [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 3718)
External Link http://www.broadinstitute.org/gsea/msigdb/cards/MORF_JAK3
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Genes

95 co-expressed genes for JAK3 from the MSigDB Cancer Gene Co-expression Modules dataset.

Symbol Name
ADAM15 ADAM metallopeptidase domain 15
AFF2 AF4/FMR2 family, member 2
AGER advanced glycosylation end product-specific receptor
AGPS alkylglycerone phosphate synthase
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase
AQP5 aquaporin 5
ARC activity-regulated cytoskeleton-associated protein
ARSE arylsulfatase E (chondrodysplasia punctata 1)
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2
BAHD1 bromo adjacent homology domain containing 1
BCL2 B-cell CLL/lymphoma 2
CAMK2G calcium/calmodulin-dependent protein kinase II gamma
CCKAR cholecystokinin A receptor
CD8B CD8b molecule
CDK13 cyclin-dependent kinase 13
CMA1 chymase 1, mast cell
CNTN2 contactin 2 (axonal)
CRCP CGRP receptor component
CYP11A1 cytochrome P450, family 11, subfamily A, polypeptide 1
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)
DPT dermatopontin
ECE2 endothelin converting enzyme 2
EXTL3 exostosin-like glycosyltransferase 3
F7 coagulation factor VII (serum prothrombin conversion accelerator)
FAM189A2 family with sequence similarity 189, member A2
FDXR ferredoxin reductase
GRIK5 glutamate receptor, ionotropic, kainate 5
GRIP2 glutamate receptor interacting protein 2
HAUS5 HAUS augmin-like complex, subunit 5
HNRNPL heterogeneous nuclear ribonucleoprotein L
HOXD4 homeobox D4
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
HTR7 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled
IGSF9B immunoglobulin superfamily, member 9B
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
IRF2 interferon regulatory factor 2
IRF2BP1 interferon regulatory factor 2 binding protein 1
ITIH4 inter-alpha-trypsin inhibitor heavy chain family, member 4
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
JAK3 Janus kinase 3
JRK Jrk homolog (mouse)
KCTD20 potassium channel tetramerization domain containing 20
KIAA0195 KIAA0195
KIFC3 kinesin family member C3
KLHL18 kelch-like family member 18
KRT33A keratin 33A, type I
LBP lipopolysaccharide binding protein
LOC166994 integral membrane glycoprotein-like
LSM12 LSM12 homolog (S. cerevisiae)
LTK leukocyte receptor tyrosine kinase
MC2R melanocortin 2 receptor (adrenocorticotropic hormone)
MLN motilin
MMP25 matrix metallopeptidase 25
MPP2 membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)
MSX1 msh homeobox 1
MT4 metallothionein 4
MYO9B myosin IXB
NEURL1 neuralized E3 ubiquitin protein ligase 1
NFRKB nuclear factor related to kappaB binding protein
PAIP2B poly(A) binding protein interacting protein 2B
PAX8 paired box 8
PAX9 paired box 9
PCBP3 poly(rC) binding protein 3
PIGB phosphatidylinositol glycan anchor biosynthesis, class B
PIGR polymeric immunoglobulin receptor
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PML promyelocytic leukemia
PVT1 Pvt1 oncogene (non-protein coding)
RANBP2 RAN binding protein 2
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RBBP8 retinoblastoma binding protein 8
SEZ6L seizure related 6 homolog (mouse)-like
SH2B1 SH2B adaptor protein 1
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SLC13A2 solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2
SLC16A5 solute carrier family 16 (monocarboxylate transporter), member 5
SLC22A24 solute carrier family 22, member 24
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SLC30A3 solute carrier family 30 (zinc transporter), member 3
SLC4A3 solute carrier family 4 (anion exchanger), member 3
SLC6A7 solute carrier family 6 (neurotransmitter transporter), member 7
SLC6A9 solute carrier family 6 (neurotransmitter transporter, glycine), member 9
SPEF1 sperm flagellar 1
SSTR5 somatostatin receptor 5
TBC1D22A TBC1 domain family, member 22A
TLN2 talin 2
TM4SF5 transmembrane 4 L six family member 5
TMEM11 transmembrane protein 11
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
WDR62 WD repeat domain 62
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZNF500 zinc finger protein 500
ZNF592 zinc finger protein 592