Dataset | MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations |
Category | transcriptomics |
Type | gene perturbation |
Description | gene perturbation identified as [gene symbol]_[perturbation or condition] (Molecular Signatures Database) |
External Link | http://www.broadinstitute.org/gsea/msigdb/cards/JNK_DN.V1_UP |
Similar Terms | |
Downloads & Tools |
379 genes differentially expressed following the JNK_DN.V1 gene perturbation from the MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations dataset.
Symbol | Name |
---|---|
ABCD1 | ATP-binding cassette, sub-family D (ALD), member 1 |
ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase |
ACADL | acyl-CoA dehydrogenase, long chain |
ACKR3 | atypical chemokine receptor 3 |
ADAM12 | ADAM metallopeptidase domain 12 |
ADAMTS3 | ADAM metallopeptidase with thrombospondin type 1 motif, 3 |
AGRP | agouti related neuropeptide |
AGTPBP1 | ATP/GTP binding protein 1 |
AGXT | alanine-glyoxylate aminotransferase |
AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) |
AKR1C3 | aldo-keto reductase family 1, member C3 |
ALOX12B | arachidonate 12-lipoxygenase, 12R type |
ANXA13 | annexin A13 |
APBA1 | amyloid beta (A4) precursor protein-binding, family A, member 1 |
ARL4A | ADP-ribosylation factor-like 4A |
ARMC8 | armadillo repeat containing 8 |
ARSF | arylsulfatase F |
B3GALT5 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 5 |
BAG2 | BCL2-associated athanogene 2 |
BEAN1 | brain expressed, associated with NEDD4, 1 |
BIRC3 | baculoviral IAP repeat containing 3 |
BMP7 | bone morphogenetic protein 7 |
BMX | BMX non-receptor tyrosine kinase |
C1S | complement component 1, s subcomponent |
C8G | complement component 8, gamma polypeptide |
CACNA1H | calcium channel, voltage-dependent, T type, alpha 1H subunit |
CACNB2 | calcium channel, voltage-dependent, beta 2 subunit |
CBX4 | chromobox homolog 4 |
CCL1 | chemokine (C-C motif) ligand 1 |
CCL15 | chemokine (C-C motif) ligand 15 |
CCL22 | chemokine (C-C motif) ligand 22 |
CCL4 | chemokine (C-C motif) ligand 4 |
CD37 | CD37 molecule |
CD83 | CD83 molecule |
CEACAM4 | carcinoembryonic antigen-related cell adhesion molecule 4 |
CGA | glycoprotein hormones, alpha polypeptide |
CLCN4 | chloride channel, voltage-sensitive 4 |
CLDN18 | claudin 18 |
CLIP3 | CAP-GLY domain containing linker protein 3 |
CRMP1 | collapsin response mediator protein 1 |
CTSZ | cathepsin Z |
CXCL11 | chemokine (C-X-C motif) ligand 11 |
CXCL8 | chemokine (C-X-C motif) ligand 8 |
DDIT3 | DNA-damage-inducible transcript 3 |
DEFA4 | defensin, alpha 4, corticostatin |
DGCR9 | DiGeorge syndrome critical region gene 9 (non-protein coding) |
DGKQ | diacylglycerol kinase, theta 110kDa |
DIAPH2-AS1 | DIAPH2 antisense RNA 1 |
DRD1 | dopamine receptor D1 |
ECM2 | extracellular matrix protein 2, female organ and adipocyte specific |
EFHD1 | EF-hand domain family, member D1 |
ELN | elastin |
EPHA3 | EPH receptor A3 |
EPHA4 | EPH receptor A4 |
EPM2A | epilepsy, progressive myoclonus type 2A, Lafora disease (laforin) |
ERVK-6 | endogenous retrovirus group K, member 6 |
EYA2 | EYA transcriptional coactivator and phosphatase 2 |
F11 | coagulation factor XI |
FAM161A | family with sequence similarity 161, member A |
FAM65B | family with sequence similarity 65, member B |
FOXA2 | forkhead box A2 |
GABRP | gamma-aminobutyric acid (GABA) A receptor, pi |
GABRR2 | gamma-aminobutyric acid (GABA) A receptor, rho 2 |
GCH1 | GTP cyclohydrolase 1 |
GHRH | growth hormone releasing hormone |
GNAZ | guanine nucleotide binding protein (G protein), alpha z polypeptide |
GPR31 | G protein-coupled receptor 31 |
GPR37L1 | G protein-coupled receptor 37 like 1 |
GPR45 | G protein-coupled receptor 45 |
GPX7 | glutathione peroxidase 7 |
HIST1H1E | histone cluster 1, H1e |
HIST1H2AK | histone cluster 1, H2ak |
HIST1H2AM | histone cluster 1, H2am |
HIST1H2BN | histone cluster 1, H2bn |
HNF1B | HNF1 homeobox B |
HOXA2 | homeobox A2 |
HOXA4 | homeobox A4 |
HOXC4 | homeobox C4 |
HR | hair growth associated |
HSD3B1 | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 |
HSPA12A | heat shock 70kDa protein 12A |
HTR6 | 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled |
IFNA2 | interferon, alpha 2 |
IGFBP3 | insulin-like growth factor binding protein 3 |
IGLV6-57 | immunoglobulin lambda variable 6-57 |
IL10RA | interleukin 10 receptor, alpha |
IL12RB1 | interleukin 12 receptor, beta 1 |
IL13RA2 | interleukin 13 receptor, alpha 2 |
INPP5J | inositol polyphosphate-5-phosphatase J |
KCND3 | potassium channel, voltage gated Shal related subfamily D, member 3 |
KCNJ5 | potassium channel, inwardly rectifying subfamily J, member 5 |
KCNJ9 | potassium channel, inwardly rectifying subfamily J, member 9 |
KCNN3 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 3 |
KCNS1 | potassium voltage-gated channel, modifier subfamily S, member 1 |
KDM5C | lysine (K)-specific demethylase 5C |
KIAA0368 | KIAA0368 |
KIAA1211L | KIAA1211-like |
KLK7 | kallikrein-related peptidase 7 |
KRT34 | keratin 34, type I |
KRT37 | keratin 37, type I |
KRT9 | keratin 9, type I |
MAN2A2 | mannosidase, alpha, class 2A, member 2 |
MAP7 | microtubule-associated protein 7 |
MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase |
MED13 | mediator complex subunit 13 |
MICU2 | mitochondrial calcium uptake 2 |
MMP17 | matrix metallopeptidase 17 (membrane-inserted) |
MPL | MPL proto-oncogene, thrombopoietin receptor |
MRAS | muscle RAS oncogene homolog |
MS4A1 | membrane-spanning 4-domains, subfamily A, member 1 |
MVD | mevalonate (diphospho) decarboxylase |
MYOM1 | myomesin 1 |
N4BP2L2 | NEDD4 binding protein 2-like 2 |
NID2 | nidogen 2 (osteonidogen) |
NLE1 | notchless homolog 1 (Drosophila) |
NOX1 | NADPH oxidase 1 |
OR2B6 | olfactory receptor, family 2, subfamily B, member 6 |
OR2J2 | olfactory receptor, family 2, subfamily J, member 2 |
PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 |
PDE4B | phosphodiesterase 4B, cAMP-specific |
PDE6A | phosphodiesterase 6A, cGMP-specific, rod, alpha |
PDK3 | pyruvate dehydrogenase kinase, isozyme 3 |
PECAM1 | platelet/endothelial cell adhesion molecule 1 |
PHKG1 | phosphorylase kinase, gamma 1 (muscle) |
PIP4K2A | phosphatidylinositol-5-phosphate 4-kinase, type II, alpha |
PLAA | phospholipase A2-activating protein |
PMCH | pro-melanin-concentrating hormone |
PMEL | premelanosome protein |
PNOC | prepronociceptin |
PPFIA4 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 |
PPP1R8 | protein phosphatase 1, regulatory subunit 8 |
PROZ | protein Z, vitamin K-dependent plasma glycoprotein |
PRR3 | proline rich 3 |
PRRG2 | proline rich Gla (G-carboxyglutamic acid) 2 |
PTPN22 | protein tyrosine phosphatase, non-receptor type 22 (lymphoid) |
PTPRCAP | protein tyrosine phosphatase, receptor type, C-associated protein |
RAB35 | RAB35, member RAS oncogene family |
RAD17 | RAD17 homolog (S. pombe) |
RASSF2 | Ras association (RalGDS/AF-6) domain family member 2 |
RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 |
RGL1 | ral guanine nucleotide dissociation stimulator-like 1 |
RNF8 | ring finger protein 8, E3 ubiquitin protein ligase |
ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 |
RRAD | Ras-related associated with diabetes |
RUNX2 | runt-related transcription factor 2 |
RUNX3 | runt-related transcription factor 3 |
S1PR1 | sphingosine-1-phosphate receptor 1 |
SCN2B | sodium channel, voltage gated, type II beta subunit |
SCNN1B | sodium channel, non voltage gated 1 beta subunit |
SERPINB3 | serpin peptidase inhibitor, clade B (ovalbumin), member 3 |
SHC3 | SHC (Src homology 2 domain containing) transforming protein 3 |
SKAP1 | src kinase associated phosphoprotein 1 |
SLC16A2 | solute carrier family 16, member 2 (thyroid hormone transporter) |
SLC22A5 | solute carrier family 22 (organic cation/carnitine transporter), member 5 |
SLC25A20 | solute carrier family 25 (carnitine/acylcarnitine translocase), member 20 |
SLC25A24 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24 |
SLC26A10 | solute carrier family 26, member 10 |
SLC34A1 | solute carrier family 34 (type II sodium/phosphate cotransporter), member 1 |
SLC6A1 | solute carrier family 6 (neurotransmitter transporter), member 1 |
SLC7A7 | solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 |
SLCO2B1 | solute carrier organic anion transporter family, member 2B1 |
SNAI2 | snail family zinc finger 2 |
SPICE1 | spindle and centriole associated protein 1 |
STARD13 | StAR-related lipid transfer (START) domain containing 13 |
STC2 | stanniocalcin 2 |
SYNE1 | spectrin repeat containing, nuclear envelope 1 |
SZRD1 | SUZ RNA binding domain containing 1 |
TACR1 | tachykinin receptor 1 |
TBX2 | T-box 2 |
TDO2 | tryptophan 2,3-dioxygenase |
TEK | TEK tyrosine kinase, endothelial |
TET3 | tet methylcytosine dioxygenase 3 |
TFEC | transcription factor EC |
TGM1 | transglutaminase 1 |
TNFSF14 | tumor necrosis factor (ligand) superfamily, member 14 |
TNFSF4 | tumor necrosis factor (ligand) superfamily, member 4 |
TNNC1 | troponin C type 1 (slow) |
TNNT2 | troponin T type 2 (cardiac) |
TRIM24 | tripartite motif containing 24 |
TRIM31 | tripartite motif containing 31 |
TSN | translin |
UGT2B15 | UDP glucuronosyltransferase 2 family, polypeptide B15 |
UHRF2 | ubiquitin-like with PHD and ring finger domains 2, E3 ubiquitin protein ligase |
UNG | uracil-DNA glycosylase |
YAP1 | Yes-associated protein 1 |
ZFHX2 | zinc finger homeobox 2 |
ZNF204P | zinc finger protein 204, pseudogene |
ZNF280B | zinc finger protein 280B |
ZNF79 | zinc finger protein 79 |
Symbol | Name |
---|---|
ABCA4 | ATP-binding cassette, sub-family A (ABC1), member 4 |
ABHD2 | abhydrolase domain containing 2 |
ACVRL1 | activin A receptor type II-like 1 |
ADAM3A | ADAM metallopeptidase domain 3A (pseudogene) |
AGO2 | argonaute RISC catalytic component 2 |
ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) |
APLP1 | amyloid beta (A4) precursor-like protein 1 |
APOBEC3F | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3F |
AR | androgen receptor |
ARHGAP4 | Rho GTPase activating protein 4 |
ARR3 | arrestin 3, retinal (X-arrestin) |
ASGR1 | asialoglycoprotein receptor 1 |
ATP2A3 | ATPase, Ca++ transporting, ubiquitous |
BCL2L11 | BCL2-like 11 (apoptosis facilitator) |
BCL9 | B-cell CLL/lymphoma 9 |
BLM | Bloom syndrome, RecQ helicase-like |
BTK | Bruton agammaglobulinemia tyrosine kinase |
C10ORF10 | chromosome 10 open reading frame 10 |
CA5BP1 | carbonic anhydrase VB pseudogene 1 |
CABP1 | calcium binding protein 1 |
CAPN11 | calpain 11 |
CCL11 | chemokine (C-C motif) ligand 11 |
CDC42EP2 | CDC42 effector protein (Rho GTPase binding) 2 |
CDC45 | cell division cycle 45 |
CDKN3 | cyclin-dependent kinase inhibitor 3 |
CHD1L | chromodomain helicase DNA binding protein 1-like |
COL13A1 | collagen, type XIII, alpha 1 |
CRX | cone-rod homeobox |
CRYBA1 | crystallin, beta A1 |
CRYM | crystallin, mu |
CTRC | chymotrypsin C (caldecrin) |
CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
DAAM2 | dishevelled associated activator of morphogenesis 2 |
DEFA3 | defensin, alpha 3, neutrophil-specific |
DENND5A | DENN/MADD domain containing 5A |
DSCR4 | Down syndrome critical region 4 |
DUSP4 | dual specificity phosphatase 4 |
DUSP8 | dual specificity phosphatase 8 |
DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 |
EFNA5 | ephrin-A5 |
EPHB1 | EPH receptor B1 |
ERVW-1 | endogenous retrovirus group W, member 1 |
ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 |
FABP6 | fatty acid binding protein 6, ileal |
FAM110B | family with sequence similarity 110, member B |
FAM131B | family with sequence similarity 131, member B |
FAM182B | family with sequence similarity 182, member B |
FASLG | Fas ligand (TNF superfamily, member 6) |
FBP2 | fructose-1,6-bisphosphatase 2 |
FER | fer (fps/fes related) tyrosine kinase |
FLRT1 | fibronectin leucine rich transmembrane protein 1 |
FXYD2 | FXYD domain containing ion transport regulator 2 |
G0S2 | G0/G1 switch 2 |
GCGR | glucagon receptor |
GCNT1 | glucosaminyl (N-acetyl) transferase 1, core 2 |
GGCX | gamma-glutamyl carboxylase |
GIT2 | G protein-coupled receptor kinase interacting ArfGAP 2 |
GJA4 | gap junction protein, alpha 4, 37kDa |
GPR12 | G protein-coupled receptor 12 |
GPR171 | G protein-coupled receptor 171 |
GRIN2C | glutamate receptor, ionotropic, N-methyl D-aspartate 2C |
HMGB3P30 | high mobility group box 3 pseudogene 30 |
HSD17B3 | hydroxysteroid (17-beta) dehydrogenase 3 |
IDUA | iduronidase, alpha-L- |
IL2RB | interleukin 2 receptor, beta |
INPPL1 | inositol polyphosphate phosphatase-like 1 |
INS | insulin |
IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
IRF8 | interferon regulatory factor 8 |
IRGC | immunity-related GTPase family, cinema |
ITGA10 | integrin, alpha 10 |
ITGB2 | integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) |
JPH3 | junctophilin 3 |
KAT5 | K(lysine) acetyltransferase 5 |
KCNA4 | potassium channel, voltage gated shaker related subfamily A, member 4 |
KCNJ8 | potassium channel, inwardly rectifying subfamily J, member 8 |
KCNV2 | potassium channel, voltage gated modifier subfamily V, member 2 |
KIF22 | kinesin family member 22 |
KIR3DL3 | killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 3 |
KLHL35 | kelch-like family member 35 |
KMT2A | lysine (K)-specific methyltransferase 2A |
KNTC1 | kinetochore associated 1 |
KPNA3 | karyopherin alpha 3 (importin alpha 4) |
KRT75 | keratin 75, type II |
LINC00342 | long intergenic non-protein coding RNA 342 |
LINC00588 | long intergenic non-protein coding RNA 588 |
LRIG2 | leucine-rich repeats and immunoglobulin-like domains 2 |
LRP8 | low density lipoprotein receptor-related protein 8, apolipoprotein e receptor |
LY86 | lymphocyte antigen 86 |
MAFK | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K |
MAP1B | microtubule-associated protein 1B |
MAT1A | methionine adenosyltransferase I, alpha |
MBNL2 | muscleblind-like splicing regulator 2 |
MCAT | malonyl CoA:ACP acyltransferase (mitochondrial) |
MFSD7 | major facilitator superfamily domain containing 7 |
MIA | melanoma inhibitory activity |
MMP2 | matrix metallopeptidase 2 |
MYL9 | myosin, light chain 9, regulatory |
NAT8 | N-acetyltransferase 8 (GCN5-related, putative) |
NDRG2 | NDRG family member 2 |
NELL2 | NEL-like 2 (chicken) |
NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
NMB | neuromedin B |
NOVA1 | neuro-oncological ventral antigen 1 |
NPR1 | natriuretic peptide receptor 1 |
NPY1R | neuropeptide Y receptor Y1 |
NR2E1 | nuclear receptor subfamily 2, group E, member 1 |
NRGN | neurogranin (protein kinase C substrate, RC3) |
NRP2 | neuropilin 2 |
OPRK1 | opioid receptor, kappa 1 |
OR7A5 | olfactory receptor, family 7, subfamily A, member 5 |
P2RX3 | purinergic receptor P2X, ligand gated ion channel, 3 |
PACRG | PARK2 co-regulated |
PAQR4 | progestin and adipoQ receptor family member IV |
PCDH9 | protocadherin 9 |
PCYT1B | phosphate cytidylyltransferase 1, choline, beta |
PDE6H | phosphodiesterase 6H, cGMP-specific, cone, gamma |
PDGFB | platelet-derived growth factor beta polypeptide |
PFAS | phosphoribosylformylglycinamidine synthase |
PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
PIP | prolactin-induced protein |
PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) |
PLCD1 | phospholipase C, delta 1 |
PLK1 | polo-like kinase 1 |
PML | promyelocytic leukemia |
POLD1 | polymerase (DNA directed), delta 1, catalytic subunit |
POP1 | processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae) |
PTP4A3 | protein tyrosine phosphatase type IVA, member 3 |
PTPN18 | protein tyrosine phosphatase, non-receptor type 18 (brain-derived) |
QSOX1 | quiescin Q6 sulfhydryl oxidase 1 |
RAB11FIP3 | RAB11 family interacting protein 3 (class II) |
RAB40A | RAB40A, member RAS oncogene family |
RAB6B | RAB6B, member RAS oncogene family |
RARA | retinoic acid receptor, alpha |
RCAN2 | regulator of calcineurin 2 |
RGS14 | regulator of G-protein signaling 14 |
RGS16 | regulator of G-protein signaling 16 |
RIMS1 | regulating synaptic membrane exocytosis 1 |
RND1 | Rho family GTPase 1 |
SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B |
SERPINF2 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 |
SERPING1 | serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 |
SGCG | sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) |
SHB | Src homology 2 domain containing adaptor protein B |
SIPA1 | signal-induced proliferation-associated 1 |
SLC12A5 | solute carrier family 12 (potassium/chloride transporter), member 5 |
SLC14A2 | solute carrier family 14 (urea transporter), member 2 |
SLC2A2 | solute carrier family 2 (facilitated glucose transporter), member 2 |
SLC6A5 | solute carrier family 6 (neurotransmitter transporter), member 5 |
SMAD9 | SMAD family member 9 |
SMAP1 | small ArfGAP 1 |
SMARCD3 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 |
SMYD2 | SET and MYND domain containing 2 |
SOGA1 | suppressor of glucose, autophagy associated 1 |
SOX10 | SRY (sex determining region Y)-box 10 |
SPINK4 | serine peptidase inhibitor, Kazal type 4 |
SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) |
SRC | SRC proto-oncogene, non-receptor tyrosine kinase |
SSX3 | synovial sarcoma, X breakpoint 3 |
STEAP1 | six transmembrane epithelial antigen of the prostate 1 |
STK35 | serine/threonine kinase 35 |
STON1 | stonin 1 |
SV2B | synaptic vesicle glycoprotein 2B |
SVEP1 | sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 |
SYT17 | synaptotagmin XVII |
TBKBP1 | TBK1 binding protein 1 |
THY1 | Thy-1 cell surface antigen |
TM4SF4 | transmembrane 4 L six family member 4 |
TNIK | TRAF2 and NCK interacting kinase |
TNS2 | tensin 2 |
TRAF6 | TNF receptor-associated factor 6, E3 ubiquitin protein ligase |
TRIM10 | tripartite motif containing 10 |
TRO | trophinin |
TSPAN2 | tetraspanin 2 |
TTLL3 | tubulin tyrosine ligase-like family member 3 |
TTTY1 | testis-specific transcript, Y-linked 1 (non-protein coding) |
TULP1 | tubby like protein 1 |
TYMP | thymidine phosphorylase |
UBE2C | ubiquitin-conjugating enzyme E2C |
UBL4A | ubiquitin-like 4A |
VASP | vasodilator-stimulated phosphoprotein |
VEGFC | vascular endothelial growth factor C |
WIPF1 | WAS/WASL interacting protein family, member 1 |
XIST | X inactive specific transcript (non-protein coding) |
YPEL1 | yippee-like 1 (Drosophila) |
ZC2HC1A | zinc finger, C2HC-type containing 1A |
ZCCHC14 | zinc finger, CCHC domain containing 14 |
ZIC2 | Zic family member 2 |
ZNF549 | zinc finger protein 549 |
ZRSR1 | zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 1 |