| Dataset | DeepCoverMOA Drug Mechanisms of Action |
| Category | proteomics |
| Type | drug perturbation |
| External Link | https://pubchem.ncbi.nlm.nih.gov/compound/10223146 |
| Similar Terms | |
| Downloads & Tools |
199 proteins with high or low expression in JTE 013 relative to other proteins from the DeepCoverMOA Drug Mechanisms of Action dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CELSR3 | cadherin, EGF LAG seven-pass G-type receptor 3 | 1.14 |
| ALK | anaplastic lymphoma receptor tyrosine kinase | 1.11 |
| DENND4B | DENN/MADD domain containing 4B | 1.07 |
| PTPRB | protein tyrosine phosphatase, receptor type, B | 1.06 |
| ADCY10 | adenylate cyclase 10 (soluble) | 0.96 |
| TIGD1 | tigger transposable element derived 1 | 0.88 |
| DCHS1 | dachsous cadherin-related 1 | 0.88 |
| HMCN1 | hemicentin 1 | 0.88 |
| WWC3 | WWC family member 3 | 0.79 |
| GALNT5 | polypeptide N-acetylgalactosaminyltransferase 5 | 0.75 |
| SLC16A6 | solute carrier family 16, member 6 | 0.64 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | 0.63 |
| MT2A | metallothionein 2A | 0.62 |
| ZSCAN26 | zinc finger and SCAN domain containing 26 | 0.61 |
| OIP5 | Opa interacting protein 5 | 0.57 |
| GVINP1 | GTPase, very large interferon inducible pseudogene 1 | 0.56 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 | 0.54 |
| STC2 | stanniocalcin 2 | 0.54 |
| ZC3H12C | zinc finger CCCH-type containing 12C | 0.54 |
| B4GAT1 | beta-1,4-glucuronyltransferase 1 | 0.53 |
| NR1D2 | nuclear receptor subfamily 1, group D, member 2 | 0.51 |
| CCDC9B | coiled-coil domain containing 9B | 0.51 |
| MKRN4P | makorin ring finger protein 4, pseudogene | 0.51 |
| DSCAM | Down syndrome cell adhesion molecule | 0.5 |
| RAD52 | RAD52 homolog (S. cerevisiae) | 0.5 |
| PLA2G6 | phospholipase A2, group VI (cytosolic, calcium-independent) | 0.49 |
| PPP4R4 | protein phosphatase 4, regulatory subunit 4 | 0.48 |
| TMEM106C | transmembrane protein 106C | 0.48 |
| MT1X | metallothionein 1X | 0.47 |
| GDF15 | growth differentiation factor 15 | 0.46 |
| PDGFA | platelet-derived growth factor alpha polypeptide | 0.45 |
| ZNF189 | zinc finger protein 189 | 0.45 |
| ALG8 | ALG8, alpha-1,3-glucosyltransferase | 0.45 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.44 |
| MT1E | metallothionein 1E | 0.43 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | 0.41 |
| LARP6 | La ribonucleoprotein domain family, member 6 | 0.41 |
| TET2 | tet methylcytosine dioxygenase 2 | 0.41 |
| SMAD3 | SMAD family member 3 | 0.4 |
| TBP | TATA box binding protein | 0.4 |
| E2F2 | E2F transcription factor 2 | 0.4 |
| TMEM179B | transmembrane protein 179B | 0.4 |
| CTDNEP1 | CTD nuclear envelope phosphatase 1 | 0.4 |
| ANAPC11 | anaphase promoting complex subunit 11 | 0.4 |
| NDUFA11 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 11, 14.7kDa | 0.4 |
| GTPBP2 | GTP binding protein 2 | 0.38 |
| MT1L | metallothionein 1L (gene/pseudogene) | 0.38 |
| SEL1L3 | sel-1 suppressor of lin-12-like 3 (C. elegans) | 0.38 |
| FBLIM1 | filamin binding LIM protein 1 | 0.38 |
| RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | 0.37 |
| CUL7 | cullin 7 | 0.37 |
| TMEM200A | transmembrane protein 200A | 0.36 |
| ULBP1 | UL16 binding protein 1 | 0.36 |
| OSTM1 | osteopetrosis associated transmembrane protein 1 | 0.36 |
| MRPL52 | mitochondrial ribosomal protein L52 | 0.36 |
| PROSER3 | proline and serine rich 3 | 0.35 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 | 0.35 |
| FOSL1 | FOS-like antigen 1 | 0.35 |
| CYBA | cytochrome b-245, alpha polypeptide | 0.35 |
| DUSP4 | dual specificity phosphatase 4 | 0.34 |
| TRIM9 | tripartite motif containing 9 | 0.34 |
| ABHD17B | abhydrolase domain containing 17B | 0.33 |
| SLF1 | SMC5-SMC6 complex localization factor 1 | 0.33 |
| OTUB2 | OTU deubiquitinase, ubiquitin aldehyde binding 2 | 0.33 |
| STX1A | syntaxin 1A (brain) | 0.32 |
| ADGRF1 | adhesion G protein-coupled receptor F1 | 0.32 |
| SVIP | small VCP/p97-interacting protein | 0.32 |
| ZNRF2 | zinc and ring finger 2, E3 ubiquitin protein ligase | 0.32 |
| B4GALNT1 | beta-1,4-N-acetyl-galactosaminyl transferase 1 | 0.32 |
| MDM1 | Mdm1 nuclear protein homolog (mouse) | 0.32 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.32 |
| SETD3 | SET domain containing 3 | 0.31 |
| SERPING1 | serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 | 0.31 |
| GTF3A | general transcription factor IIIA | 0.31 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.31 |
| TTC17 | tetratricopeptide repeat domain 17 | 0.31 |
| C11ORF68 | chromosome 11 open reading frame 68 | 0.31 |
| KLHL5 | kelch-like family member 5 | 0.31 |
| PSMB9 | proteasome (prosome, macropain) subunit, beta type, 9 | 0.31 |
| ABAT | 4-aminobutyrate aminotransferase | 0.31 |
| ZNF205 | zinc finger protein 205 | 0.31 |
| RNF41 | ring finger protein 41, E3 ubiquitin protein ligase | 0.31 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.31 |
| PABPN1 | poly(A) binding protein, nuclear 1 | 0.31 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.31 |
| TNFRSF6B | tumor necrosis factor receptor superfamily, member 6b, decoy | 0.3 |
| FASTK | Fas-activated serine/threonine kinase | 0.3 |
| TRIB3 | tribbles pseudokinase 3 | 0.3 |
| JUN | jun proto-oncogene | 0.3 |
| SELENOK | selenoprotein K | 0.3 |
| ODC1 | ornithine decarboxylase 1 | 0.29 |
| ARMC7 | armadillo repeat containing 7 | 0.29 |
| TRIM62 | tripartite motif containing 62 | 0.29 |
| MPV17L2 | MPV17 mitochondrial membrane protein-like 2 | 0.29 |
| GPR180 | G protein-coupled receptor 180 | 0.29 |
| PRRX2 | paired related homeobox 2 | 0.29 |
| NDUFA3 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa | 0.29 |
| PSEN2 | presenilin 2 | 0.29 |
| EIF3C | eukaryotic translation initiation factor 3, subunit C | 0.29 |
| B3GALNT1 | beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group) | 0.28 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FGGY | FGGY carbohydrate kinase domain containing | -0.86 |
| AHR | aryl hydrocarbon receptor | -0.85 |
| FDFT1 | farnesyl-diphosphate farnesyltransferase 1 | -0.55 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | -0.55 |
| FGB | fibrinogen beta chain | -0.52 |
| ELK3 | ELK3, ETS-domain protein (SRF accessory protein 2) | -0.5 |
| TAPT1 | transmembrane anterior posterior transformation 1 | -0.49 |
| FAM171A1 | family with sequence similarity 171, member A1 | -0.48 |
| TSPAN3 | tetraspanin 3 | -0.47 |
| FAM117B | family with sequence similarity 117, member B | -0.45 |
| MSMO1 | methylsterol monooxygenase 1 | -0.45 |
| ZNF518B | zinc finger protein 518B | -0.45 |
| PFKFB1 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 | -0.45 |
| DUSP6 | dual specificity phosphatase 6 | -0.45 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | -0.44 |
| FN1 | fibronectin 1 | -0.43 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | -0.43 |
| FXN | frataxin | -0.43 |
| PROS1 | protein S (alpha) | -0.43 |
| KITLG | KIT ligand | -0.42 |
| JAG1 | jagged 1 | -0.42 |
| SLC29A2 | solute carrier family 29 (equilibrative nucleoside transporter), member 2 | -0.42 |
| POMGNT1 | protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-) | -0.4 |
| ARL16 | ADP-ribosylation factor-like 16 | -0.4 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 | -0.36 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.36 |
| DNAJC24 | DnaJ (Hsp40) homolog, subfamily C, member 24 | -0.35 |
| MCFD2 | multiple coagulation factor deficiency 2 | -0.35 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.35 |
| SS18 | synovial sarcoma translocation, chromosome 18 | -0.35 |
| KDELR2 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 | -0.35 |
| CFAP47 | cilia and flagella associated protein 47 | -0.35 |
| ZNRD2 | zinc ribbon domain containing 2 | -0.35 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.34 |
| CHST7 | carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7 | -0.34 |
| SATB2 | SATB homeobox 2 | -0.33 |
| E2F1 | E2F transcription factor 1 | -0.33 |
| ENTR1 | endosome associated trafficking regulator 1 | -0.32 |
| S100A14 | S100 calcium binding protein A14 | -0.32 |
| DBI | diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) | -0.32 |
| IRF5 | interferon regulatory factor 5 | -0.31 |
| TSEN15 | TSEN15 tRNA splicing endonuclease subunit | -0.31 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.31 |
| ZNF594 | zinc finger protein 594 | -0.3 |
| SLC37A4 | solute carrier family 37 (glucose-6-phosphate transporter), member 4 | -0.3 |
| TVP23C | trans-golgi network vesicle protein 23 homolog C (S. cerevisiae) | -0.3 |
| ZMAT3 | zinc finger, matrin-type 3 | -0.3 |
| ATP11A | ATPase, class VI, type 11A | -0.3 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | -0.3 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.3 |
| TECPR1 | tectonin beta-propeller repeat containing 1 | -0.3 |
| ZC3H12A | zinc finger CCCH-type containing 12A | -0.3 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.29 |
| PPTC7 | PTC7 protein phosphatase homolog (S. cerevisiae) | -0.29 |
| SGK3 | serum/glucocorticoid regulated kinase family, member 3 | -0.29 |
| CD320 | CD320 molecule | -0.29 |
| SQLE | squalene epoxidase | -0.29 |
| FAM193A | family with sequence similarity 193, member A | -0.29 |
| ADAT3 | adenosine deaminase, tRNA-specific 3 | -0.29 |
| KRT222 | keratin 222, type II | -0.28 |
| FTL | ferritin, light polypeptide | -0.28 |
| ZNF469 | zinc finger protein 469 | -0.28 |
| TMCO6 | transmembrane and coiled-coil domains 6 | -0.28 |
| UQCRH | ubiquinol-cytochrome c reductase hinge protein | -0.28 |
| MXRA7 | matrix-remodelling associated 7 | -0.28 |
| CLDN3 | claudin 3 | -0.28 |
| EVL | Enah/Vasp-like | -0.28 |
| GALT | galactose-1-phosphate uridylyltransferase | -0.28 |
| MTHFR | methylenetetrahydrofolate reductase (NAD(P)H) | -0.27 |
| CNTNAP1 | contactin associated protein 1 | -0.27 |
| NARF | nuclear prelamin A recognition factor | -0.27 |
| FKBP2 | FK506 binding protein 2, 13kDa | -0.27 |
| DPCD | deleted in primary ciliary dyskinesia homolog (mouse) | -0.27 |
| ACSM3 | acyl-CoA synthetase medium-chain family member 3 | -0.27 |
| ELK4 | ELK4, ETS-domain protein (SRF accessory protein 1) | -0.27 |
| ZFP36 | ZFP36 ring finger protein | -0.26 |
| CYTH2 | cytohesin 2 | -0.26 |
| MYO15A | myosin XVA | -0.26 |
| VAV1 | vav 1 guanine nucleotide exchange factor | -0.26 |
| ANKS6 | ankyrin repeat and sterile alpha motif domain containing 6 | -0.26 |
| PSAP | prosaposin | -0.26 |
| TMEM51 | transmembrane protein 51 | -0.26 |
| PEF1 | penta-EF-hand domain containing 1 | -0.26 |
| MOCS1 | molybdenum cofactor synthesis 1 | -0.26 |
| F10 | coagulation factor X | -0.26 |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase | -0.25 |
| SH3BGRL | SH3 domain binding glutamate-rich protein like | -0.25 |
| TK2 | thymidine kinase 2, mitochondrial | -0.25 |
| TMEM98 | transmembrane protein 98 | -0.25 |
| SPIDR | scaffolding protein involved in DNA repair | -0.25 |
| EPHA1 | EPH receptor A1 | -0.25 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -0.25 |
| MEGF8 | multiple EGF-like-domains 8 | -0.24 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.24 |
| ARHGAP22 | Rho GTPase activating protein 22 | -0.24 |
| LDLR | low density lipoprotein receptor | -0.24 |
| KALRN | kalirin, RhoGEF kinase | -0.24 |
| GID4 | GID complex subunit 4 | -0.24 |
| CLSTN1 | calsyntenin 1 | -0.24 |
