JUN Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description jun proto-oncogene|This gene is the putative transforming gene of avian sarcoma virus 17. It encodes a protein which is highly similar to the viral protein, and which interacts directly with specific target DNA sequences to regulate gene expression. This gene is intronless and is mapped to 1p32-p31, a chromosomal region involved in both translocations and deletions in human malignancies. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 3725)
External Link https://ncbi.nlm.nih.gov/gene/3725
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Genes

500 genes differentially expressed following the JUN gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
PROM1 prominin 1 0.0124894
IFI27 interferon, alpha-inducible protein 27 0.0112137
POSTN periostin, osteoblast specific factor 0.0106641
FABP4 fatty acid binding protein 4, adipocyte 0.0101201
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 0.0101065
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase) 0.00967896
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 0.00965266
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein 0.00949677
CYTL1 cytokine-like 1 0.00946724
IGFBP2 insulin-like growth factor binding protein 2, 36kDa 0.0093227
FCGBP Fc fragment of IgG binding protein 0.00905757
EGR1 early growth response 1 0.00864025
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila) 0.00862392
TENT5A terminal nucleotidyltransferase 5A 0.00844832
COL4A1 collagen, type IV, alpha 1 0.00842935
PLXND1 plexin D1 0.0084269
CCL2 chemokine (C-C motif) ligand 2 0.00837094
OLFML2A olfactomedin-like 2A 0.00835423
CCNA2 cyclin A2 0.00812793
ACTA2 actin, alpha 2, smooth muscle, aorta 0.0079004
HLA-B major histocompatibility complex, class I, B 0.00777239
DUSP6 dual specificity phosphatase 6 0.00774403
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 0.00772291
GPX2 glutathione peroxidase 2 0.00769676
TFPI2 tissue factor pathway inhibitor 2 0.00763628
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 0.00754446
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein 0.0075139
SYNM synemin, intermediate filament protein 0.00748217
GNAS GNAS complex locus 0.00746232
CFB complement factor B 0.00743366
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) 0.00742201
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 0.00740756
IFITM1 interferon induced transmembrane protein 1 0.00727093
SLC27A3 solute carrier family 27 (fatty acid transporter), member 3 0.0071225
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10 0.0070991
COL15A1 collagen, type XV, alpha 1 0.00707082
RGS16 regulator of G-protein signaling 16 0.00701751
AQP1 aquaporin 1 (Colton blood group) 0.00700579
STAT1 signal transducer and activator of transcription 1, 91kDa 0.00698659
G6PD glucose-6-phosphate dehydrogenase 0.00697927
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.00697425
MBNL2 muscleblind-like splicing regulator 2 0.00695363
NID1 nidogen 1 0.00695276
CXCL2 chemokine (C-X-C motif) ligand 2 0.00695009
HSPA2 heat shock 70kDa protein 2 0.00690605
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9 0.00689861
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28 0.00687228
IRS2 insulin receptor substrate 2 0.00682646
COG7 component of oligomeric golgi complex 7 0.00679004
IFI6 interferon, alpha-inducible protein 6 0.00677432
GPRC5B G protein-coupled receptor, class C, group 5, member B 0.00676513
CREG1 cellular repressor of E1A-stimulated genes 1 0.00675835
UBE2L6 ubiquitin-conjugating enzyme E2L 6 0.00675522
HSPA1A heat shock 70kDa protein 1A 0.00674374
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 0.00673326
SOBP sine oculis binding protein homolog (Drosophila) 0.00669081
RHOBTB3 Rho-related BTB domain containing 3 0.00668263
F3 coagulation factor III (thromboplastin, tissue factor) 0.00667083
HLA-F major histocompatibility complex, class I, F 0.00660158
MXRA5 matrix-remodelling associated 5 0.0065693
TPM1 tropomyosin 1 (alpha) 0.00654898
PODXL podocalyxin-like 0.00653992
ATP9A ATPase, class II, type 9A 0.00653879
CTSA cathepsin A 0.00652347
ERBB2 erb-b2 receptor tyrosine kinase 2 0.00652162
ACTG2 actin, gamma 2, smooth muscle, enteric 0.00647994
RFTN1 raftlin, lipid raft linker 1 0.00646733
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding) 0.00646471
CXCL8 chemokine (C-X-C motif) ligand 8 0.0064519
NPIPB3 nuclear pore complex interacting protein family, member B3 0.00642593
LAMC1 laminin, gamma 1 (formerly LAMB2) 0.00641963
C3 complement component 3 0.00640044
GANAB glucosidase, alpha; neutral AB 0.00639737
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 0.00639258
CP ceruloplasmin (ferroxidase) 0.00639099
C1S complement component 1, s subcomponent 0.00639057
PIP prolactin-induced protein 0.00638949
MTUS1 microtubule associated tumor suppressor 1 0.00637551
IER5 immediate early response 5 0.00634368
LAMA4 laminin, alpha 4 0.0063244
TNFRSF21 tumor necrosis factor receptor superfamily, member 21 0.00631778
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 0.00631247
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) 0.00628278
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 0.00627706
TIMP1 TIMP metallopeptidase inhibitor 1 0.00622001
CEBPB CCAAT/enhancer binding protein (C/EBP), beta 0.00620486
MGP matrix Gla protein 0.0061184
APOD apolipoprotein D 0.00608952
MRC2 mannose receptor, C type 2 0.00608131
FSTL1 follistatin-like 1 0.00607292
LAMB1 laminin, beta 1 0.0060576
HLA-C major histocompatibility complex, class I, C 0.00604972
HES1 hes family bHLH transcription factor 1 0.00603715
RPN2 ribophorin II 0.00602816
BTN3A3 butyrophilin, subfamily 3, member A3 0.00600578
ITM2A integral membrane protein 2A 0.00596883
AMIGO2 adhesion molecule with Ig-like domain 2 0.00596534
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) 0.00594238
IFITM3 interferon induced transmembrane protein 3 0.00593841
TAGLN transgelin 0.00593344
FKBP11 FK506 binding protein 11, 19 kDa 0.0059152
TAPBP TAP binding protein (tapasin) 0.00591316
ISG15 ISG15 ubiquitin-like modifier 0.00590776
IL6 interleukin 6 0.00589562
APOLD1 apolipoprotein L domain containing 1 0.00588693
BTN3A2 butyrophilin, subfamily 3, member A2 0.00588605
RNASET2 ribonuclease T2 0.00588352
SORL1 sortilin-related receptor, L(DLR class) A repeats containing 0.00585895
ADGRF5 adhesion G protein-coupled receptor F5 0.00585876
CD34 CD34 molecule 0.00584623
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila) 0.00584597
TGOLN2 trans-golgi network protein 2 0.00584509
A2M alpha-2-macroglobulin 0.00583664
AKR1C2 aldo-keto reductase family 1, member C2 0.00582537
CX3CL1 chemokine (C-X3-C motif) ligand 1 0.00581473
S100P S100 calcium binding protein P 0.00580026
CHI3L2 chitinase 3-like 2 0.00579629
NUPR1 nuclear protein, transcriptional regulator, 1 0.00578236
SLPI secretory leukocyte peptidase inhibitor 0.00577143
AKR1C3 aldo-keto reductase family 1, member C3 0.00576489
CRABP1 cellular retinoic acid binding protein 1 0.00574694
BST2 bone marrow stromal cell antigen 2 0.00573528
CASP8 caspase 8, apoptosis-related cysteine peptidase 0.00573491
OXA1L oxidase (cytochrome c) assembly 1-like 0.00573005
PXDN peroxidasin 0.00571701
ZNF91 zinc finger protein 91 0.00570454
ASS1 argininosuccinate synthase 1 0.00569623
TRIM14 tripartite motif containing 14 0.00567029
CA2 carbonic anhydrase II 0.00566251
ELF5 E74-like factor 5 (ets domain transcription factor) 0.00564684
JUN jun proto-oncogene 0.00564032
COL9A3 collagen, type IX, alpha 3 0.0056315
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 0.00562758
SPP1 secreted phosphoprotein 1 0.00562404
PLXDC1 plexin domain containing 1 0.00559337
ANGPT2 angiopoietin 2 0.00559064
ZC3H11A zinc finger CCCH-type containing 11A 0.00558438
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12 0.00554201
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 0.0055413
NEDD9 neural precursor cell expressed, developmentally down-regulated 9 0.00553256
CMAHP cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene 0.00549762
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 0.00549556
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 0.00548474
PKD1P1 polycystic kidney disease 1 (autosomal dominant) pseudogene 1 0.00548002
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1 0.00547689
INHBB inhibin, beta B 0.00545517
PEG10 paternally expressed 10 0.00545166
PMP22 peripheral myelin protein 22 0.00543597
SPRY4 sprouty homolog 4 (Drosophila) 0.00543483
MYH10 myosin, heavy chain 10, non-muscle 0.00540978
GPI glucose-6-phosphate isomerase 0.00539283
IFI44L interferon-induced protein 44-like 0.00538002
ADGRG6 adhesion G protein-coupled receptor G6 0.00537806
PAN2 PAN2 poly(A) specific ribonuclease subunit 0.00537347
CARHSP1 calcium regulated heat stable protein 1, 24kDa 0.0053649
OSBPL10 oxysterol binding protein-like 10 0.0053602
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2 0.00535857
USP11 ubiquitin specific peptidase 11 0.0053565
TNS3 tensin 3 0.00535203
IFIT3 interferon-induced protein with tetratricopeptide repeats 3 0.00535193
GOLGA8A golgin A8 family, member A 0.00534091
SLC6A14 solute carrier family 6 (amino acid transporter), member 14 0.00532894
FOSB FBJ murine osteosarcoma viral oncogene homolog B 0.00532617
CTSH cathepsin H 0.0053192
BAMBI BMP and activin membrane-bound inhibitor 0.00531023
SGK1 serum/glucocorticoid regulated kinase 1 0.005295
LIMCH1 LIM and calponin homology domains 1 0.00527809
PLXNA1 plexin A1 0.00527742
HIST1H2BD histone cluster 1, H2bd 0.00526569
ARHGEF40 Rho guanine nucleotide exchange factor (GEF) 40 0.00525695
CA12 carbonic anhydrase XII 0.00524937
FNDC3B fibronectin type III domain containing 3B 0.00524722
ERAP2 endoplasmic reticulum aminopeptidase 2 0.00522308
ZC3HAV1 zinc finger CCCH-type, antiviral 1 0.00522209
GUSB glucuronidase, beta 0.00519117
AKR1C1 aldo-keto reductase family 1, member C1 0.0051691
AZGP1 alpha-2-glycoprotein 1, zinc-binding 0.00516895
BCHE butyrylcholinesterase 0.00516286
SGCE sarcoglycan, epsilon 0.0051479
NUAK1 NUAK family, SNF1-like kinase, 1 0.00513673
NPIPA1 nuclear pore complex interacting protein family, member A1 0.00512313
TSPAN8 tetraspanin 8 0.00511963
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) 0.00511172
AQP3 aquaporin 3 (Gill blood group) 0.00510274
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa 0.00510045
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2 0.00509641
PDXDC1 pyridoxal-dependent decarboxylase domain containing 1 0.00509577
DMD dystrophin 0.00509041
WWC3 WWC family member 3 0.0050799
QPRT quinolinate phosphoribosyltransferase 0.00507798
GSDMB gasdermin B 0.00506533
PDGFD platelet derived growth factor D 0.00505617
ITPKB inositol-trisphosphate 3-kinase B 0.00503242
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1 0.00502684
CCND3 cyclin D3 0.00501596
KRT23 keratin 23, type I 0.00501566
DMTF1 cyclin D binding myb-like transcription factor 1 0.00500709
PGAP3 post-GPI attachment to proteins 3 0.00499898
JUNB jun B proto-oncogene 0.00498869
IFI44 interferon-induced protein 44 0.0049722
SOD2 superoxide dismutase 2, mitochondrial 0.00494985
RGS1 regulator of G-protein signaling 1 0.00493303
MXRA7 matrix-remodelling associated 7 0.00492892
BGN biglycan 0.00492814
MYO1B myosin IB 0.00491214
MX2 MX dynamin-like GTPase 2 0.00487898
TP53BP1 tumor protein p53 binding protein 1 0.00487744
BTN3A1 butyrophilin, subfamily 3, member A1 0.00487695
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 0.00487174
GNE glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase 0.00486887
HLA-E major histocompatibility complex, class I, E 0.0048529
ATP2A3 ATPase, Ca++ transporting, ubiquitous 0.00485139
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 0.00484024
ERAP1 endoplasmic reticulum aminopeptidase 1 0.00481768
TRANK1 tetratricopeptide repeat and ankyrin repeat containing 1 0.00479871
ABHD4 abhydrolase domain containing 4 0.0047836
PDE4B phosphodiesterase 4B, cAMP-specific 0.0047835
AGTR1 angiotensin II receptor, type 1 0.00477474
P4HB prolyl 4-hydroxylase, beta polypeptide 0.00476875
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) 0.00475745
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 0.00474921
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A 0.0047421
PYCARD PYD and CARD domain containing 0.00474166
ENAH enabled homolog (Drosophila) 0.00472681
GYPC glycophorin C (Gerbich blood group) 0.0047102
PLVAP plasmalemma vesicle associated protein 0.00470944
PADI2 peptidyl arginine deiminase, type II 0.00470501
PPIC peptidylprolyl isomerase C (cyclophilin C) 0.00469881
VEGFA vascular endothelial growth factor A 0.00469693
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 0.00469376
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) 0.004688
PON3 paraoxonase 3 0.00468649
LTF lactotransferrin 0.00468321
HLA-G major histocompatibility complex, class I, G 0.0046828
ALAS1 5'-aminolevulinate synthase 1 0.00468005
C5 complement component 5 0.00467704
RBPMS RNA binding protein with multiple splicing 0.00465103
SOX4 SRY (sex determining region Y)-box 4 0.00464858
PRPS2 phosphoribosyl pyrophosphate synthetase 2 0.00464107
GDF15 growth differentiation factor 15 0.0046401
C1R complement component 1, r subcomponent 0.00463329
HOMER1 homer scaffolding protein 1 0.00461687
RARRES3 retinoic acid receptor responder (tazarotene induced) 3 0.00461391
CLEC2B C-type lectin domain family 2, member B 0.00461007
FNBP1 formin binding protein 1 0.00459449
COCH cochlin 0.00458913
NKG7 natural killer cell granule protein 7 0.00456971
UBA7 ubiquitin-like modifier activating enzyme 7 0.00454946
ERP29 endoplasmic reticulum protein 29 0.00454662
BAX BCL2-associated X protein 0.0045429

decreased expression

Symbol Name Standardized Value
LAMP5 lysosomal-associated membrane protein family, member 5 -0.0102507
BEX1 brain expressed, X-linked 1 -0.00950702
SPON1 spondin 1, extracellular matrix protein -0.00893771
GSTO1 glutathione S-transferase omega 1 -0.00837516
GLIPR1 GLI pathogenesis-related 1 -0.00831714
CD9 CD9 molecule -0.00793522
STEAP1 six transmembrane epithelial antigen of the prostate 1 -0.0078656
AHNAK2 AHNAK nucleoprotein 2 -0.00786047
ESR1 estrogen receptor 1 -0.00776489
WASHC4 WASH complex subunit 4 -0.00754911
MAL mal, T-cell differentiation protein -0.00753223
HOXB6 homeobox B6 -0.00744793
HOXC6 homeobox C6 -0.00735874
HOXB2 homeobox B2 -0.00720992
AOC1 amine oxidase, copper containing 1 -0.00716147
NTS neurotensin -0.00715409
SFN stratifin -0.00704317
LTBP1 latent transforming growth factor beta binding protein 1 -0.00700258
SNAP25 synaptosomal-associated protein, 25kDa -0.00687561
REG1A regenerating islet-derived 1 alpha -0.00683895
ME2 malic enzyme 2, NAD(+)-dependent, mitochondrial -0.00683234
ADIRF adipogenesis regulatory factor -0.00675906
CXCL14 chemokine (C-X-C motif) ligand 14 -0.00659921
PDZK1 PDZ domain containing 1 -0.00651975
ACP3 acid phosphatase 3 -0.0064861
TBX3 T-box 3 -0.00646691
SQOR sulfide quinone oxidoreductase -0.00637758
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6 -0.00636469
MSLN mesothelin -0.00629916
EPHB2 EPH receptor B2 -0.00626808
NEFH neurofilament, heavy polypeptide -0.00624387
CAPZA2 capping protein (actin filament) muscle Z-line, alpha 2 -0.00621836
KRT6A keratin 6A, type II -0.00617616
MKNK1 MAP kinase interacting serine/threonine kinase 1 -0.00614465
ARL3 ADP-ribosylation factor-like 3 -0.00605974
LPXN leupaxin -0.00605926
LDOC1 leucine zipper, down-regulated in cancer 1 -0.00600574
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 -0.00594316
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1 -0.00592222
UGCG UDP-glucose ceramide glucosyltransferase -0.00580485
ILK integrin-linked kinase -0.00577553
C7 complement component 7 -0.0057534
ANPEP alanyl (membrane) aminopeptidase -0.00572587
FHOD3 formin homology 2 domain containing 3 -0.00570135
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1 -0.00568188
HMG20B high mobility group 20B -0.00566468
MTERF3 mitochondrial transcription termination factor 3 -0.00565974
ST6GALNAC5 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 -0.00558777
PLEKHF2 pleckstrin homology domain containing, family F (with FYVE domain) member 2 -0.0055756
ARMT1 acidic residue methyltransferase 1 -0.00553944
G0S2 G0/G1 switch 2 -0.00548632
RGS4 regulator of G-protein signaling 4 -0.00547608
CCK cholecystokinin -0.0053632
LAMC2 laminin, gamma 2 -0.00535951
VBP1 von Hippel-Lindau binding protein 1 -0.00535726
SMS spermine synthase -0.00533496
TNNT1 troponin T type 1 (skeletal, slow) -0.00532323
TCF21 transcription factor 21 -0.00531071
SSBP2 single-stranded DNA binding protein 2 -0.00528005
STMN2 stathmin 2 -0.00525573
SORD sorbitol dehydrogenase -0.00524975
LY86 lymphocyte antigen 86 -0.00522578
C3ORF14 chromosome 3 open reading frame 14 -0.0052257
TXNDC9 thioredoxin domain containing 9 -0.00520603
NDP Norrie disease (pseudoglioma) -0.00509344
COPS7A COP9 signalosome subunit 7A -0.00507117
TBC1D9 TBC1 domain family, member 9 (with GRAM domain) -0.00506712
RPS4Y1 ribosomal protein S4, Y-linked 1 -0.00504495
THBS1 thrombospondin 1 -0.00504397
GINS2 GINS complex subunit 2 (Psf2 homolog) -0.00502216
SYT1 synaptotagmin I -0.00500572
SUB1 SUB1 homolog (S. cerevisiae) -0.00495308
GPX1 glutathione peroxidase 1 -0.00492083
CTSZ cathepsin Z -0.00489168
MGAM maltase-glucoamylase -0.00488528
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3 -0.00486715
MRPL39 mitochondrial ribosomal protein L39 -0.00486698
ENO2 enolase 2 (gamma, neuronal) -0.00486421
KIF1B kinesin family member 1B -0.0048086
DHDDS dehydrodolichyl diphosphate synthase -0.0048
S100A6 S100 calcium binding protein A6 -0.00479615
PEG3 paternally expressed 3 -0.00479351
S100A2 S100 calcium binding protein A2 -0.00477527
NBL1 neuroblastoma 1, DAN family BMP antagonist -0.00477204
RETREG1 reticulophagy regulator 1 -0.00476904
MAMLD1 mastermind-like domain containing 1 -0.00475222
STMN1 stathmin 1 -0.00474964
SEPP1 selenoprotein P, plasma, 1 -0.00473699
PEA15 phosphoprotein enriched in astrocytes 15 -0.004736
RBX1 ring-box 1, E3 ubiquitin protein ligase -0.00473101
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit -0.00472091
PPP3CB protein phosphatase 3, catalytic subunit, beta isozyme -0.00471437
TPM4 tropomyosin 4 -0.00470197
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit -0.00470104
NR2F1 nuclear receptor subfamily 2, group F, member 1 -0.00469931
SMTN smoothelin -0.00467578
GLRX3 glutaredoxin 3 -0.00467188
TLR4 toll-like receptor 4 -0.00466786
RNF19B ring finger protein 19B -0.0046616
RAI2 retinoic acid induced 2 -0.00465919
LSR lipolysis stimulated lipoprotein receptor -0.00465237
MAPKAPK3 mitogen-activated protein kinase-activated protein kinase 3 -0.0046463
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta -0.00464412
SDHAF3 succinate dehydrogenase complex assembly factor 3 -0.00460507
NELL1 NEL-like 1 (chicken) -0.00459549
CRYM crystallin, mu -0.00459141
CDC42 cell division cycle 42 -0.00458833
TIGAR TP53 induced glycolysis regulatory phosphatase -0.00458305
SHOX2 short stature homeobox 2 -0.00456977
SLIT2 slit homolog 2 (Drosophila) -0.00456217
KRT19 keratin 19, type I -0.00455525
COMMD8 COMM domain containing 8 -0.0045516
HPF1 histone PARylation factor 1 -0.00455091
IRF8 interferon regulatory factor 8 -0.00454762
GPRC5A G protein-coupled receptor, class C, group 5, member A -0.00453997
SPRR1B small proline-rich protein 1B -0.00452171
KLK6 kallikrein-related peptidase 6 -0.00450851
MRPL13 mitochondrial ribosomal protein L13 -0.00450683
CCND2 cyclin D2 -0.0044983
EMP1 epithelial membrane protein 1 -0.00449433
PAGE4 P antigen family, member 4 (prostate associated) -0.00449317
AP1S2 adaptor-related protein complex 1, sigma 2 subunit -0.00448343
REG1B regenerating islet-derived 1 beta -0.00444615
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 -0.00444363
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 -0.00443753
FRG1 FSHD region gene 1 -0.00442812
RBBP8 retinoblastoma binding protein 8 -0.00442226
BANK1 B-cell scaffold protein with ankyrin repeats 1 -0.00441977
ADK adenosine kinase -0.00441923
FAIM Fas apoptotic inhibitory molecule -0.00439825
FOXF1 forkhead box F1 -0.00439609
BPGM 2,3-bisphosphoglycerate mutase -0.00439517
NIT2 nitrilase family, member 2 -0.00438791
KLK7 kallikrein-related peptidase 7 -0.00437538
REG3A regenerating islet-derived 3 alpha -0.00437491
C12ORF29 chromosome 12 open reading frame 29 -0.00437096
TMEM126B transmembrane protein 126B -0.00435624
EREG epiregulin -0.00432643
TCL1A T-cell leukemia/lymphoma 1A -0.00431737
SELENOW selenoprotein W -0.00430254
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase) -0.00429401
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme -0.00429113
ZBTB18 zinc finger and BTB domain containing 18 -0.00429082
RPA2 replication protein A2, 32kDa -0.004283
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide -0.00426106
ZC2HC1A zinc finger, C2HC-type containing 1A -0.0042448
PDCD10 programmed cell death 10 -0.00424206
CHKB choline kinase beta -0.0042352
RNF41 ring finger protein 41, E3 ubiquitin protein ligase -0.00422462
RAB23 RAB23, member RAS oncogene family -0.00422441
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) -0.00422416
GCA grancalcin, EF-hand calcium binding protein -0.00422399
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 -0.00420746
SLIRP SRA stem-loop interacting RNA binding protein -0.00420383
DEFA4 defensin, alpha 4, corticostatin -0.00420247
ELOVL6 ELOVL fatty acid elongase 6 -0.00419999
ITGB1BP1 integrin beta 1 binding protein 1 -0.00419954
VRK1 vaccinia related kinase 1 -0.00418024
YEATS4 YEATS domain containing 4 -0.00416504
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D -0.00413929
SLC25A14 solute carrier family 25 (mitochondrial carrier, brain), member 14 -0.00413672
TMEM14A transmembrane protein 14A -0.00413571
S100A12 S100 calcium binding protein A12 -0.0041312
WWP1 WW domain containing E3 ubiquitin protein ligase 1 -0.00412601
CLNS1A chloride channel, nucleotide-sensitive, 1A -0.00412391
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 -0.00411916
SRC SRC proto-oncogene, non-receptor tyrosine kinase -0.00411429
RHCG Rh family, C glycoprotein -0.00411303
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7 -0.00410847
FBXO3 F-box protein 3 -0.00410828
CETN2 centrin, EF-hand protein, 2 -0.00410812
IPO13 importin 13 -0.00410685
SELL selectin L -0.0041059
ENC1 ectodermal-neural cortex 1 (with BTB domain) -0.00409965
NT5DC2 5'-nucleotidase domain containing 2 -0.00409872
CRYZ crystallin, zeta (quinone reductase) -0.00407883
DHRS9 dehydrogenase/reductase (SDR family) member 9 -0.00407058
NREP neuronal regeneration related protein -0.00406868
TNFAIP8 tumor necrosis factor, alpha-induced protein 8 -0.00405878
RIMBP2 RIMS binding protein 2 -0.00405145
FKBP14 FK506 binding protein 14, 22 kDa -0.00403857
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 -0.00403341
MMP10 matrix metallopeptidase 10 -0.00403314
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O -0.00402716
PSMD13 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 -0.00402557
RPA3 replication protein A3, 14kDa -0.00401708
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A -0.00400862
CLCA1 chloride channel accessory 1 -0.00400634
LSM1 LSM1, U6 small nuclear RNA associated -0.00399997
SAMHD1 SAM domain and HD domain 1 -0.00398817
DPYSL3 dihydropyrimidinase-like 3 -0.00398731
S100A13 S100 calcium binding protein A13 -0.00398546
NEBL nebulette -0.00398294
KLF10 Kruppel-like factor 10 -0.00397941
ELMO3 engulfment and cell motility 3 -0.0039741
ARID4A AT rich interactive domain 4A (RBP1-like) -0.00397015
AMD1 adenosylmethionine decarboxylase 1 -0.0039696
NUDT2 nudix (nucleoside diphosphate linked moiety X)-type motif 2 -0.00395875
NPEPPS aminopeptidase puromycin sensitive -0.00395286
OLFM4 olfactomedin 4 -0.00394831
PPID peptidylprolyl isomerase D -0.00394706
LSM4 LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) -0.00394634
ANKS1B ankyrin repeat and sterile alpha motif domain containing 1B -0.00393272
NUDT21 nudix (nucleoside diphosphate linked moiety X)-type motif 21 -0.00393252
AIMP1 aminoacyl tRNA synthetase complex-interacting multifunctional protein 1 -0.00392922
ALDOB aldolase B, fructose-bisphosphate -0.00392537
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 -0.00392406
RIMS3 regulating synaptic membrane exocytosis 3 -0.00391884
POLR2L polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa -0.00391645
MDFIC MyoD family inhibitor domain containing -0.0039092
HIGD1A HIG1 hypoxia inducible domain family, member 1A -0.0039075
CCNA1 cyclin A1 -0.00390431
MRPL19 mitochondrial ribosomal protein L19 -0.00390154
DACH1 dachshund family transcription factor 1 -0.003898
SKP1 S-phase kinase-associated protein 1 -0.00389776
NCF2 neutrophil cytosolic factor 2 -0.00389486
FPR3 formyl peptide receptor 3 -0.00389436
CPNE3 copine III -0.0038897
DDX52 DEAD (Asp-Glu-Ala-Asp) box polypeptide 52 -0.0038832
NUDT11 nudix (nucleoside diphosphate linked moiety X)-type motif 11 -0.00388081
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1 -0.00387901
CDC45 cell division cycle 45 -0.00387231
GNAI3 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 -0.00387023
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 -0.00386288
PDLIM7 PDZ and LIM domain 7 (enigma) -0.00386167
IL15 interleukin 15 -0.00386004
GET1 guided entry of tail-anchored proteins factor 1 -0.00385149
MYCBP MYC binding protein -0.00385071
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2 -0.00383329
DERA deoxyribose-phosphate aldolase (putative) -0.00383228
ECI2 enoyl-CoA delta isomerase 2 -0.00382552
ACOT7 acyl-CoA thioesterase 7 -0.00382482
ACE2 angiotensin I converting enzyme 2 -0.00382188
TOX3 TOX high mobility group box family member 3 -0.00381893
EFHD2 EF-hand domain family, member D2 -0.00381195
CHN1 chimerin 1 -0.00381188
BIN1 bridging integrator 1 -0.00380737
NAV3 neuron navigator 3 -0.00380115
SLC30A9 solute carrier family 30 (zinc transporter), member 9 -0.00378745
PAK1IP1 PAK1 interacting protein 1 -0.00378541
CDA cytidine deaminase -0.00378267
QDPR quinoid dihydropteridine reductase -0.0037765
ODC1 ornithine decarboxylase 1 -0.00376665
UPK1B uroplakin 1B -0.00376567
CCR2 chemokine (C-C motif) receptor 2 -0.00376052
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) -0.00375948
MT1M metallothionein 1M -0.00375868
SSX2IP synovial sarcoma, X breakpoint 2 interacting protein -0.00375346
CIAPIN1 cytokine induced apoptosis inhibitor 1 -0.00374394
ATP5IF1 ATP synthase inhibitory factor subunit 1 -0.00374387