JURL-MK1 Gene Set

Dataset COSMIC Cell Line Gene Mutation Profiles
Category genomics
Type cell line
Description cell line derived from haematopoietic and lymphoid tissue (Cancer Cell Line Encyclopedia)
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Genes

345 genes mutated in the JURL-MK1 cell line from the COSMIC Cell Line Gene Mutation Profiles dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1
ACP5 acid phosphatase 5, tartrate resistant
ADGRF4 adhesion G protein-coupled receptor F4
ADPRHL1 ADP-ribosylhydrolase like 1
ADRB1 adrenoceptor beta 1
ALDH3B2 aldehyde dehydrogenase 3 family, member B2
ALS2 amyotrophic lateral sclerosis 2 (juvenile)
AMY2B amylase, alpha 2B (pancreatic)
ANKMY2 ankyrin repeat and MYND domain containing 2
ANKRD27 ankyrin repeat domain 27 (VPS9 domain)
ANKRD36C ankyrin repeat domain 36C
ANXA10 annexin A10
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B
AQP7 aquaporin 7
ARFGEF1 ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited)
ARHGAP5 Rho GTPase activating protein 5
ARID1B AT rich interactive domain 1B (SWI1-like)
ARMC2 armadillo repeat containing 2
ASCC3 activating signal cointegrator 1 complex subunit 3
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
ATP6V0A4 ATPase, H+ transporting, lysosomal V0 subunit a4
B3GNTL1 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1
BAG5 BCL2-associated athanogene 5
BAHCC1 BAH domain and coiled-coil containing 1
BCHE butyrylcholinesterase
BCOR BCL6 corepressor
BIRC6 baculoviral IAP repeat containing 6
BRDT bromodomain, testis-specific
BTBD9 BTB (POZ) domain containing 9
C6 complement component 6
CACNA2D1 calcium channel, voltage-dependent, alpha 2/delta subunit 1
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CACNG4 calcium channel, voltage-dependent, gamma subunit 4
CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
CADPS Ca++-dependent secretion activator
CALB2 calbindin 2
CALR3 calreticulin 3
CAMK2D calcium/calmodulin-dependent protein kinase II delta
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2
CC2D1A coiled-coil and C2 domain containing 1A
CCDC146 coiled-coil domain containing 146
CCDC80 coiled-coil domain containing 80
CCDC94 coiled-coil domain containing 94
CCNJL cyclin J-like
CD1B CD1b molecule
CDK10 cyclin-dependent kinase 10
CEP350 centrosomal protein 350kDa
CEP76 centrosomal protein 76kDa
CEP89 centrosomal protein 89kDa
CES5A carboxylesterase 5A
CFAP70 cilia and flagella associated protein 70
CHD1L chromodomain helicase DNA binding protein 1-like
CHD7 chromodomain helicase DNA binding protein 7
CHIA chitinase, acidic
CHRNA6 cholinergic receptor, nicotinic, alpha 6 (neuronal)
CKAP5 cytoskeleton associated protein 5
CLEC1A C-type lectin domain family 1, member A
CLPTM1 cleft lip and palate associated transmembrane protein 1
CMYA5 cardiomyopathy associated 5
COL13A1 collagen, type XIII, alpha 1
COL21A1 collagen, type XXI, alpha 1
CORO7 coronin 7
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CREG2 cellular repressor of E1A-stimulated genes 2
CRIPAK cysteine-rich PAK1 inhibitor
CRISP1 cysteine-rich secretory protein 1
CSMD1 CUB and Sushi multiple domains 1
CSMD2 CUB and Sushi multiple domains 2
CSNK1G1 casein kinase 1, gamma 1
CTAGE1 cutaneous T-cell lymphoma-associated antigen 1
CTDSPL2 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
CUL9 cullin 9
CYB561D1 cytochrome b561 family, member D1
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
DLC1 DLC1 Rho GTPase activating protein
DMBT1 deleted in malignant brain tumors 1
DMTF1 cyclin D binding myb-like transcription factor 1
DNAH5 dynein, axonemal, heavy chain 5
DOCK10 dedicator of cytokinesis 10
DOCK2 dedicator of cytokinesis 2
DOCK9 dedicator of cytokinesis 9
DSPP dentin sialophosphoprotein
DVL3 dishevelled segment polarity protein 3
DYNC1I1 dynein, cytoplasmic 1, intermediate chain 1
DYSF dysferlin
ECT2L epithelial cell transforming 2 like
EFR3A EFR3 homolog A (S. cerevisiae)
EIF3M eukaryotic translation initiation factor 3, subunit M
EPHA3 EPH receptor A3
ERBB4 erb-b2 receptor tyrosine kinase 4
EXT1 exostosin glycosyltransferase 1
EYA2 EYA transcriptional coactivator and phosphatase 2
EYS eyes shut homolog (Drosophila)
FAM169A family with sequence similarity 169, member A
FAM186B family with sequence similarity 186, member B
FAM19A3 family with sequence similarity 19 (chemokine (C-C motif)-like), member A3
FARP2 FERM, RhoGEF and pleckstrin domain protein 2
FBXL4 F-box and leucine-rich repeat protein 4
FCRL3 Fc receptor-like 3
FILIP1 filamin A interacting protein 1
FLNA filamin A, alpha
FOXO1 forkhead box O1
FTCD formimidoyltransferase cyclodeaminase
GABRR1 gamma-aminobutyric acid (GABA) A receptor, rho 1
GFI1B growth factor independent 1B transcription repressor
GH2 growth hormone 2
GLI2 GLI family zinc finger 2
GLT1D1 glycosyltransferase 1 domain containing 1
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
GNB4 guanine nucleotide binding protein (G protein), beta polypeptide 4
GNPTAB N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
GP6 glycoprotein VI (platelet)
GPRIN2 G protein regulated inducer of neurite outgrowth 2
GSTT1 glutathione S-transferase theta 1
GZMH granzyme H (cathepsin G-like 2, protein h-CCPX)
HAPLN3 hyaluronan and proteoglycan link protein 3
HIPK4 homeodomain interacting protein kinase 4
HJURP Holliday junction recognition protein
HLA-A major histocompatibility complex, class I, A
HOOK2 hook microtubule-tethering protein 2
HPS6 Hermansky-Pudlak syndrome 6
HSD17B13 hydroxysteroid (17-beta) dehydrogenase 13
HUNK hormonally up-regulated Neu-associated kinase
ICAM3 intercellular adhesion molecule 3
IFNL1 interferon, lambda 1
IFT81 intraflagellar transport 81
IKZF1 IKAROS family zinc finger 1 (Ikaros)
INSL5 insulin-like 5
INTS8 integrator complex subunit 8
IPP intracisternal A particle-promoted polypeptide
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit)
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
KCNC3 potassium channel, voltage gated Shaw related subfamily C, member 3
KCNH1 potassium channel, voltage gated eag related subfamily H, member 1
KCNU1 potassium channel, subfamily U, member 1
KDM4B lysine (K)-specific demethylase 4B
KIAA0141 KIAA0141
KIAA1324 KIAA1324
KIAA1683 KIAA1683
KIAA1755 KIAA1755
KIAA2026 KIAA2026
KIF21A kinesin family member 21A
KLK7 kallikrein-related peptidase 7
KMT2D lysine (K)-specific methyltransferase 2D
KPTN kaptin (actin binding protein)
KRT35 keratin 35, type I
KRT7 keratin 7, type II
LCK LCK proto-oncogene, Src family tyrosine kinase
LEPR leptin receptor
LETM1 leucine zipper-EF-hand containing transmembrane protein 1
LMAN2L lectin, mannose-binding 2-like
LPP LIM domain containing preferred translocation partner in lipoma
LRRCC1 leucine rich repeat and coiled-coil centrosomal protein 1
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
LYST lysosomal trafficking regulator
LZTS1 leucine zipper, putative tumor suppressor 1
MAN1C1 mannosidase, alpha, class 1C, member 1
MAN2B1 mannosidase, alpha, class 2B, member 1
MCM5 minichromosome maintenance complex component 5
MCM9 minichromosome maintenance complex component 9
MCPH1 microcephalin 1
MED23 mediator complex subunit 23
MED26 mediator complex subunit 26
MFAP4 microfibrillar-associated protein 4
MFSD10 major facilitator superfamily domain containing 10
MGAM maltase-glucoamylase
MIOX myo-inositol oxygenase
MLH1 mutL homolog 1
MMACHC methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria
MNDA myeloid cell nuclear differentiation antigen
MRPL38 mitochondrial ribosomal protein L38
MS4A5 membrane-spanning 4-domains, subfamily A, member 5
MTL5 metallothionein-like 5, testis-specific (tesmin)
MTMR8 myotubularin related protein 8
MUC12 mucin 12, cell surface associated
MUC16 mucin 16, cell surface associated
MUC4 mucin 4, cell surface associated
MYOM3 myomesin 3
MYT1 myelin transcription factor 1
N4BP2L1 NEDD4 binding protein 2-like 1
NCAPD3 non-SMC condensin II complex, subunit D3
NDST1 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
NEB nebulin
NEU2 sialidase 2 (cytosolic sialidase)
NFU1 NFU1 iron-sulfur cluster scaffold
NISCH nischarin
NKIRAS1 NFKB inhibitor interacting Ras-like 1
NLRX1 NLR family member X1
NOTCH2NL notch 2 N-terminal like
NPY5R neuropeptide Y receptor Y5
NRXN3 neurexin 3
NTAN1 N-terminal asparagine amidase
NTRK1 neurotrophic tyrosine kinase, receptor, type 1
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
NUDT6 nudix (nucleoside diphosphate linked moiety X)-type motif 6
OBSCN obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
ODF2 outer dense fiber of sperm tails 2
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
OGN osteoglycin
OR4A16 olfactory receptor, family 4, subfamily A, member 16
OR4N2 olfactory receptor, family 4, subfamily N, member 2
OR5H6 olfactory receptor, family 5, subfamily H, member 6 (gene/pseudogene)
PACS2 phosphofurin acidic cluster sorting protein 2
PAPOLG poly(A) polymerase gamma
PAPSS1 3'-phosphoadenosine 5'-phosphosulfate synthase 1
PARK2 parkin RBR E3 ubiquitin protein ligase
PCDH1 protocadherin 1
PCDH15 protocadherin-related 15
PCDHGA8 protocadherin gamma subfamily A, 8
PCNT pericentrin
PCNXL3 pecanex-like 3 (Drosophila)
PCSK9 proprotein convertase subtilisin/kexin type 9
PDPR pyruvate dehydrogenase phosphatase regulatory subunit
PELI2 pellino E3 ubiquitin protein ligase family member 2
PENK proenkephalin
PEX19 peroxisomal biogenesis factor 19
PEX6 peroxisomal biogenesis factor 6
PF4 platelet factor 4
PIAS4 protein inhibitor of activated STAT, 4
PIEZO2 piezo-type mechanosensitive ion channel component 2
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PITPNM2 phosphatidylinositol transfer protein, membrane-associated 2
PITRM1 pitrilysin metallopeptidase 1
PKD1 polycystic kidney disease 1 (autosomal dominant)
PKD1L1 polycystic kidney disease 1 like 1
PKMYT1 protein kinase, membrane associated tyrosine/threonine 1
PLEKHD1 pleckstrin homology domain containing, family D (with coiled-coil domains) member 1
PLEKHN1 pleckstrin homology domain containing, family N member 1
PMM1 phosphomannomutase 1
POLR3E polymerase (RNA) III (DNA directed) polypeptide E (80kD)
POR P450 (cytochrome) oxidoreductase
POSTN periostin, osteoblast specific factor
PPIP5K2 diphosphoinositol pentakisphosphate kinase 2
PRDM6 PR domain containing 6
PRDM9 PR domain containing 9
PREB prolactin regulatory element binding
PRG4 proteoglycan 4
PRSS21 protease, serine, 21 (testisin)
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTPRS protein tyrosine phosphatase, receptor type, S
RB1CC1 RB1-inducible coiled-coil 1
RBPJ recombination signal binding protein for immunoglobulin kappa J region
REL v-rel avian reticuloendotheliosis viral oncogene homolog
RGAG1 retrotransposon gag domain containing 1
RHBDD1 rhomboid domain containing 1
RIMBP3 RIMS binding protein 3
RNF17 ring finger protein 17
RP1L1 retinitis pigmentosa 1-like 1
RPIA ribose 5-phosphate isomerase A
RRP8 ribosomal RNA processing 8, methyltransferase, homolog (yeast)
RYR2 ryanodine receptor 2 (cardiac)
SAMD4B sterile alpha motif domain containing 4B
SAR1B secretion associated, Ras related GTPase 1B
SCNN1B sodium channel, non voltage gated 1 beta subunit
SDAD1 SDA1 domain containing 1
SDCBP2 syndecan binding protein (syntenin) 2
SEMA5B sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B
SETX senataxin
SGSM1 small G protein signaling modulator 1
SH2D2A SH2 domain containing 2A
SH2D3C SH2 domain containing 3C
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SIDT2 SID1 transmembrane family, member 2
SIN3A SIN3 transcription regulator family member A
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
SLC13A1 solute carrier family 13 (sodium/sulfate symporter), member 1
SLC13A2 solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2
SLC24A5 solute carrier family 24 (sodium/potassium/calcium exchanger), member 5
SLC25A46 solute carrier family 25, member 46
SLC30A3 solute carrier family 30 (zinc transporter), member 3
SLC35F2 solute carrier family 35, member F2
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5
SLC6A1 solute carrier family 6 (neurotransmitter transporter), member 1
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SLFN12L schlafen family member 12-like
SLFN13 schlafen family member 13
SLX4 SLX4 structure-specific endonuclease subunit
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
SORBS3 sorbin and SH3 domain containing 3
SPAM1 sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding)
SPTA1 spectrin, alpha, erythrocytic 1
SPTBN5 spectrin, beta, non-erythrocytic 5
SQLE squalene epoxidase
SRSF5 serine/arginine-rich splicing factor 5
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
SUSD4 sushi domain containing 4
SUV420H1 suppressor of variegation 4-20 homolog 1 (Drosophila)
SYT15 synaptotagmin XV
SYT3 synaptotagmin III
TARSL2 threonyl-tRNA synthetase-like 2
TAS1R3 taste receptor, type 1, member 3
TBC1D2 TBC1 domain family, member 2
TET3 tet methylcytosine dioxygenase 3
TGM6 transglutaminase 6
TLR10 toll-like receptor 10
TM2D1 TM2 domain containing 1
TMEM215 transmembrane protein 215
TMPRSS4 transmembrane protease, serine 4
TMPRSS7 transmembrane protease, serine 7
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNXB tenascin XB
TOP2B topoisomerase (DNA) II beta 180kDa
TOR1AIP1 torsin A interacting protein 1
TP53 tumor protein p53
TPR translocated promoter region, nuclear basket protein
TPRN taperin
TRANK1 tetratricopeptide repeat and ankyrin repeat containing 1
TRAPPC3 trafficking protein particle complex 3
TRIM5 tripartite motif containing 5
TRIM73 tripartite motif containing 73
TSLIG3B tRNA splicing ligase complex subunit 3B
TSPYL6 TSPY-like 6
TTN titin
TXNRD1 thioredoxin reductase 1
UNC93A unc-93 homolog A (C. elegans)
USF2 upstream transcription factor 2, c-fos interacting
USP49 ubiquitin specific peptidase 49
VCAM1 vascular cell adhesion molecule 1
VILL villin-like
VSIG4 V-set and immunoglobulin domain containing 4
VWA5B1 von Willebrand factor A domain containing 5B1
VWDE von Willebrand factor D and EGF domains
WDR11 WD repeat domain 11
WDR76 WD repeat domain 76
WHSC1L1 Wolf-Hirschhorn syndrome candidate 1-like 1
WWOX WW domain containing oxidoreductase
YAP1 Yes-associated protein 1
YJEFN3 YjeF N-terminal domain containing 3
ZBED4 zinc finger, BED-type containing 4
ZBTB43 zinc finger and BTB domain containing 43
ZDHHC17 zinc finger, DHHC-type containing 17
ZMYM6 zinc finger, MYM-type 6
ZNF223 zinc finger protein 223
ZNF292 zinc finger protein 292
ZNF44 zinc finger protein 44
ZNF529 zinc finger protein 529
ZNF764 zinc finger protein 764
ZNF862 zinc finger protein 862
ZNF91 zinc finger protein 91
ZNF99 zinc finger protein 99